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Research Article

Influence of capsule shell composition on the performance indicators of hypromellose capsule in comparison to hard gelatin capsules

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Pages 1726-1737 | Received 24 Jul 2014, Accepted 20 Dec 2014, Published online: 14 Jan 2015

References

  • Jones BE. Manufacture and properties of two-piece hard capsules. In: Podczeck F, Jones BE, eds. Pharmaceutical capsules. 2nd ed. London: Pharmaceutical Press; 2004:79–88
  • Ogura T, Furuya Y, Matsuura S. HPMC capsules: an alternative to gelatin. Pharm Tech Eur 1998; Publication No. 0310
  • Ku MS, Li W, Dulin W, et al. Performance qualification of a new hypromellose capsule: part I. Comparative evaluation of physical, mechanical and processability quality attributes of Vcaps Plus, Quali-V and gelatin capsules. Int J Pharm 2010;386:30–41
  • Al-Tabakha MM. HPMC capsules: current status and future prospects. J Pharm Pharmaceut Sci 2010;13:428–42
  • Torrisi BM, Birchall JC, Jones BE, et al. The development of a sensitive methodology to characterise hardshell capsule puncture by dry powder inhaler pins. Int J Pharm 2013;456:545–52
  • Al-Tabakha MM, Arida AI. A study of the effect of jet milling process with or without pre-treatment on aerosolisation characteristics of FITC-dextran particles. J Med J 2006;40:250–61
  • Nakate T, Yoshida H, Ohike A, et al. Formulation development of inhalation powders for FK888 using the E-haler to improve the inhalation performance at a high dose, and its absorption in healthy volunteers. Eur J Pharm Biopharm 2005;59:25–33
  • Ku MS, Lu Q, Li W, Chen Y. Performance qualification of a new hypromellose capsule: part II. Disintegration and dissolution comparison between two types of hypromellose capsules. Int J Pharm 2011;416:16–24
  • Jones BE, Podczeck F. Letter to the Editor: on the performance qualification of hypromellose capsules. Int J Pharm 2012;434:503–6
  • Jones BE, Podczeck F. “Performance qualification of a new hypromellose capsule. Part I. Comparative evaluation of physical, mechanical and processability quality attributes of Vcaps Plus, Quali-V and gelatincapsules and Part II. Disintegration and dissolution comparison between two types of hypromellosecapsules” by M. Sherry Ku et al. Int J Pharm 2012;423:589–92
  • Hard gelatin capsules, USP General Test Chapters on DISINTEGRATION <701>, USP 37-NF 32, The United States Pharmacopeial Convention, Rockville, MD
  • Immediate Release Dosage forms, Apparatus 1 (Basket Method), USP General Test Chapters on DISSOLUTION <711>, USP 37-NF 32, The United States Pharmacopeial Convention, Rockville, MD
  • Jones BE, Basit AW, Tuleu C. The disintegration behaviour of capsules in fed subjects: a comparison of hypromellose (carrageenan) capsules and standard gelatin capsules. Int J Pharm 2012;424:40–3
  • Tuleu C, Khela MK, Evans DF, et al. A scintigraphic investigation of the disintegration behaviour of capsules in fasting subjects: a comparison of hypromellose capsules containing carrageenan as a gelling agent and standard gelatin capsules. Int J Pharm 2012;423:589–92
  • Garbacz G, Cadé D, Benameur H, Weitschies W. Bio-relevant dissolution testing of hard capsules prepared from different shell materials using the dynamic open flow through test apparatus. Eur J Pharm Sci 2014;57:264–72
  • Chiwele I, Jones BE, Podczeck F. The shell dissolution of various empty hard capsules. Chem Pharm Bull 2000;48:951–6
  • El-Malah Y, Nazzal S, Bottom CB. Hard gelatin and hypromellose (HPMC) capsules: estimation of rupture time by real-time dissolution spectroscopy. Drug Dev Ind Pharm 2007;33:27–34
  • Cao QR, Choi JS, Liu Y, et al. A formulation approach for development of HPMC-based sustained release tablets for tolterodine tartrate with a low release variation. Drug Dev Ind Pharm 2013;39:1720–30
  • Rogers TL, Wallick D. Reviewing the use of ethylcellulose, methylcellulose and hypromellose in microencapsulation. Part 3: applications for microcapsules. Drug Dev Ind Pharm 2012;38:521–39
  • Rogers TL, Wallick D. Reviewing the use of ethylcellulose, methylcellulose and hypromellose in microencapsulation. Part 1: materials used to formulate microcapsules. Drug Dev Ind Pharm 2012;38:129–57
  • Rogers TL, Wallick D. Reviewing the use of ethylcellulose, methylcellulose and hypromellose in microencapsulation. Part 2: techniques used to make microcapsules. Drug Dev Ind Pharm 2011;37:1259–71
  • Zhang L, Wang Y, Liu H, et al. Developing hydroxypropyl methylcellulose/hydroxypropyl starch blends for use as capsule materials. Carbohydr Polym 2013;98:73–9
  • Donauer N, Löbenberg R. Historical perspective: a mini review of scientific and pharmacopeial requirements for the disintegration test. Int J Pharm 2007;345:2–8
  • Ouellet D, Grossmann KF, Limentani G, et al. Effects of particle size, food, and capsule shell composition on the oral bioavailability of dabrafenib, a BRAF inhibitor, in patients with BRAF mutation-positive tumors. J Pharm Sci 2013;102:3100–9

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