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Research Article

Formulation and pharmacokinetics of gelucire solid dispersions of flurbiprofen

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Pages 1254-1262 | Received 10 Mar 2014, Accepted 26 Jun 2014, Published online: 21 Jul 2014

References

  • Emara LH, Badr RM, Abd EA. Improving the dissolution and bioavailability of nifidepine using solid dispersion and solubilizers. Drug Dev Ind Pharm 2002;28:795–807
  • Kaushik D, Dureja H, Saini TR. Mouth dissolving tablets: a review. Indian Drugs 2004;41:187–93
  • Chang R, Guo X, Burnside B, Couch R. A review of fast dissolving tablets. Pharm Tech 2000;24:52–8
  • Bhaskar C, Shyam S, Anant P. Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique. Eur J Pharm Sci 2005;26:219–30
  • Patil MP, Gaikwad NJ. Preparation and characterization of gliclazide-polyethylene glycol 4000 solid dispersions. Acta Pharm 2009;59:57–65
  • Vippagunta SR, Maul KA, Tallavajhala S, Grant DJW. Solid state characterization of nifedipine solid dispersions. Int J Pharm 2002;236:111–23
  • Veerareddy PR, Vemula SK. Formulation, evaluation and pharmacokinetics of colon targeted pulsatile system of flurboprofen. J Drug Target 2012;20:703–14
  • Vemula SK, Veerareddy PR. Fast disintegrating tablets of flurbiprofen: formulation and characterization. Lat Am J Pharm 2011;30:1135–41
  • Mettu SR, Veerareddy PR. Formulation, evaluation and pharmacokinetics of flurbiprofen fast dissolving tablets. Brit J Pharm Res 2013;3:617–31
  • Patel JH, Tiwari P, Patel JS. Solid dispersion based tablets of poorly soluble drug flurbiprofen. Am J Pharmtech Res 2011;1:18–24
  • Chauhan B, Shimpi S, Paradkar A. Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique. Eur J Pharm Sci 2005;26:219–30
  • Devireddy SR, Veerareddy PR. Solubility and bioavailability improvement of glcclazide by solid dispersions using novel carriers. Int J Drug Del 2012;4:455–61
  • Potluri RHK, Bandari S, Jukanti R, Veerareddy PR. Solubility enhancement and physicochemical characterization of carvedilol solid dispersion with gelucire 50/13. Arch Pharm Res 2011;34:51–7
  • Sinha S, Ali M, Baboota S, et al. Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir. AAPS PharmSciTech 2010;11:518–27
  • Faisal W, O’Hora TR, O’Driscoll CMM, Griffin BT. A novel lipid-based solid dispersion for enhancing oral bioavailability of lycopene-in vivo evaluation using a pig model. Int J Pharm 2013;453:307–14
  • Vemula SK, Veerareddy PR. Formulation, evaluation and pharmacokinetics of ketorolac tromethamine time-dependent colon targeted drug delivery system. Exp Opin Drug Del 2013;10:33–45
  • Gohel M, Patel M, Amin A, et al. Formulation design and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique. AAPS PharmSciTech 2004;5:36–41
  • Mathews BR. Regulatory aspects of stability testing in Europe. Drug Dev Ind Pharm 1999;25:831–56
  • Vemula SK, Bontha VK. Colon targeted gaur gm compression coated tablets of flrbiprofen: formulation, development and pharmacokinetics. Bio Med Res Int 2013;Article ID 287919 (Article in Press)
  • Staniforth JN, Aulton ME. Aulton’s pharmaceutics – the design and manufacture of medicines. New York: Churchill Livingstone; 2007
  • Grahnen A. Design of bioavailability studies. Pharm Int 1984;5:100–3
  • Dordunoo SK, Ford JL, Rubinstein MH. Preformulation studies on solid dispersions containing triamterene or temazepam in polyethylene glycols or gelucire 44/14 for liquid filling of hard gelatin capsules. Drug Dev Ind Pharm 1991;17:1685–713
  • Passerini N, Perissutti B, Moneghini M, et al. Characterization of carmazepinegelucire 50/13 microparticles prepared by a spray-congealing process using ultrasounds. J Pharm Sci 2002;91:699–707
  • Bandarkar SF, Ibrahim SK. Lyophilized gliclazidepoloxamer, solid dispersions for enhancement of in vitro dissolution and in vivo bioavailability. Int J Pharm Pharm Sci 2011;3:122–7

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