Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting

References

• Paulus W, Jellinger K. The neuropathologic basis of different clinical subgroups of Parkinson’s disease. J Neuropathol Exp Neurol 1991;50:743–55
   PubMed Web of Science ®Google Scholar
• Hely MA, Morris J, Reid WGJ. Sydney multicenter study of Parkinson’s disease: non-motor problems dominate at 15 years. Mov Disord 2005;20:190–9
   PubMed Web of Science ®Google Scholar
• Md S, Haque S, Sahni JK, et al. New non-oral drug delivery systems for Parkinson’s disease treatment. Expert Opin Drug Deliv 2011;8:359–74
   PubMed Web of Science ®Google Scholar
• Kaye CM, Nicholls B. Clinical pharmacokinetics of ropinirole. Clin Pharmacokinet 2000;39:243–54
   PubMed Web of Science ®Google Scholar
• Md S, Kumar M, Baboota S, et al. Preparation, characterization and evaluation of bromocriptine loaded chitosan nanoparticles for intranasal delivery. Sci Adv Mater 2012;4:961–5
   Web of Science ®Google Scholar
• Ugwoke MI, Verbeke N, Kinget R. The biopharmaceutical aspects of nasal mucoadhesive drug delivery. J Pharm Pharmacol 2001;53:3–21
   PubMed Web of Science ®Google Scholar
• Critchley H, Davis SS, Farraj NF. Nasal absorption of desmopressin in rats and sheep. Effect of a bioadhesive microsphere delivery system. J Pharm Pharmacol 1994;46:651–6
   PubMed Web of Science ®Google Scholar
• Khan S, Patil K, Bobade N, et al. Formulation of intranasal mucoadhesive temperature-mediated in situ gel containing ropinirole and evaluation of brain targeting efficiency in rats. J Drug Target 2010;18:223–34
   PubMed Web of Science ®Google Scholar
• Mustafa G, Baboota S, Ali J, Ahuja A. Formulation development of chitosan coated intra nasal ropinirole nanoemulsion for better management option of Parkinson: an in vitro–ex vivo evaluation. Curr Nanosci 2012;29:293–300
   Google Scholar
• Dondeti P, Zia H, Needham TE. Bioadhesive and formulation parameters affecting nasal absorption. Int J Pharm 1996;127:115–33
   Web of Science ®Google Scholar
• Illum L, Farraj N, Critchley H. Nasal administration of gentamicin using a novel microsphere delivery system. Int J Pharm 1988;46:261–5
   Web of Science ®Google Scholar
• Fazil M, Md S, Haque S, et al. Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting. Eur J Pharm Sci 2012;47:6–15
   PubMed Web of Science ®Google Scholar
• Haque S, Md S, Fazil M, et al. Venlafaxine loaded chitosan NPs for brain targeting: pharmacokinetic and pharmacodynamic evaluation. Carbohydr Polym 2012;89:72–9
   PubMed Web of Science ®Google Scholar
• Md S, Khan RA, Mustafa G, et al. Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model. Eur J Pharm Sci 2013;48:393–405
   PubMed Web of Science ®Google Scholar
• Calvo P, Remunan-Lopez C, Vila-Jata JL, Alonso MJ. Chitosan and chitosan: ethylene oxide–propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharm Res 1997;14:1431–6
   PubMed Web of Science ®Google Scholar
• Papadimitriou S, Bikiaris D, Avgoustakis K, et al. Chitosan nanoparticles loaded with dorzolamide and pramipexole. Carbohydr Polym 2008;73:44–54
   Web of Science ®Google Scholar
• Marchal-Heussler L, Maincent P, Hoffman M, et al. Antiglaucomatous activity of betaxolol chlorhydrate sorbed onto different isobutyl cyanoacrylate nanoparticles preparations. Int J Pharm 1990;58:115–22
   Web of Science ®Google Scholar
• Korsemeyer RW, Gurny R, Docler E, et al. Mechanism of solute release from porous hydrophilic polymer. Int J Pharm 1983;15:25–35
   Web of Science ®Google Scholar
• Ritger PL, Peppas NA. A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Control Release 1987;5:37–42
   Google Scholar
• Samad A, Sultana Y, Khar RK, et al. Radiolabeling and evaluation of alginate blend-isoniazid microspheres by 99mTc for the treatment of tuberculosis in rabbit model. J Drug Target 2008;16:509–15
   PubMed Web of Science ®Google Scholar
• Saha GB, ed. Methods of radiolabeling. In: Physics and radiobiology of nuclear medicine. New York: Springer-verlag; 1993:100–6
   Google Scholar
• Koziara JM, Lockman PR, Allen DD, Mumper RJ. In situ blood–brain barrier transport of nanoparticles. Pharm Res 2003;20:1772–8
   PubMed Web of Science ®Google Scholar
• Pietrowky R, Thieman A, Kern W, et al. A nose–brain pathway for psychotropic peptides, evidence from a brain evolved potential study with cholecystokinin. Psychoneuroendocrinology 1996;21:559–72
   PubMed Web of Science ®Google Scholar
• Avadi MR, Sadeghi AMM, Mohammadpour N, et al. Preparation and characterization of insulin nanoparticles using chitosan and Arabic gum with ionic gelation method. Nanomed: Nanotech Biol Med 2010;6:58–63
   PubMed Web of Science ®Google Scholar
• Motwani SK, Chopra S, Talegaonkar S, et al. Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: formulation, optimization and in vitro characterization. Eur J Pharm Biopharm 2008;68:513–25
   PubMed Web of Science ®Google Scholar
• Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci 2002;6:319–27
   Web of Science ®Google Scholar
• Muller RH, Jacobs C, Kayser O. Nanosuspensions as particulate drug formulations in therapy, rationale for development and what we can expect for the future. Adv Drug Deliv Rev 2001;47:3–19
   PubMed Web of Science ®Google Scholar
• Wang X, Chi N, Tang X. Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting. Eur J Pharm Biopharm 2008;70:735–40
   PubMed Web of Science ®Google Scholar
• Wan A, Gao Li SY, Huili L. Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study. Carbohydr Polym 2009;75:566–74
   Web of Science ®Google Scholar
• Zhou SB, Deng XM, Li XH. Investigation on a novel core-coated microspheres protein delivery system. J Control Release 2001;75:27–36
   PubMed Web of Science ®Google Scholar
• Sadeghi A, Dorkoosh FA, Avadi MR, et al. Preparation, characterization and antibacterial activities of chitosan, TMC and DEMC nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods. Int J Pharm 2008;355:299–306
   PubMed Web of Science ®Google Scholar
• Qizhi Z, Jiang X, Xiang W, et al. Preparation of nimodipine loaded microemulsion for intranasal delivery and evaluation of the targeting efficiency to brain. Int J Pharm 2004;275:85–96
   PubMed Web of Science ®Google Scholar
• Vyas TK, Shahiwala A, Marathe S, Misra A. Intranasal drug delivery for brain targeting. Curr Drug Deliv 2005;2:165–75
   PubMedGoogle Scholar
• Vyas TK, Babber AK, Sharma RK, et al. Preliminary brain targeting studies on intranasal mucoadhesive microemulsions of sumatriptan. AAPS PharmSciTech 2006;7:1–9
   PubMed Web of Science ®Google Scholar