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Drug Development and Industrial Pharmacy Volume 24, 1998 - Issue 9

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Research Article

A Mixture Experiment Approach for Controlling the Dissolution Rate of a Sustained-Release Tablet

Jean-Marie Geoffroy Abbott Laboratories, North Chicago, Illinois, 0064-4000

Jennifer K. Fredrickson Perrigo, Allegan, Michigan, 49010

John T. Shelton Hoechst Marion Roussel, Kansas City, Missouri, 64134-0627

Pages 799-806 | Published online: 20 Oct 2008

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https://doi.org/10.3109/03639049809088524

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Higuchi T. Mechanism of sustained-action medication- Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci. 1963; 52: 1145–1149
PubMed Web of Science ®Google Scholar
Cornell J. A. Experiments with Mixtures: Designs, Models, and the Analysis of Mixture Data, 2nd ed. John Wiley & Sons, Inc., New York 1990, Chapters 4 and 7
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