120
Views
7
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLESCellular and Molecular Biology

Nuclear Factor-Kappa B Inhibition Reduces Markedly Cell Proliferation in Epstein-Barr Virus-Infected Stomach Cancer, But Affects Variably in Epstein-Barr Virus-Negative Stomach Cancer

, , , , , , , , , & show all
Pages 113-119 | Published online: 07 Dec 2009

REFERENCES

  • Epstein, M.A.; Achong, B.G.; Barr, Y.M. Virus particles in cultured lymphoblasts from Burkitt's lymphoma. Lancet 1964, 1, 702–703.
  • Kieff, E.; Rickinson, A.B. Epstein-Barr virus and its replication. In Fields Virology , 4th, B.N. Fields, D.M. Knipe, and P. Howley, ( eds.). Philadelpia: Lippincott-Raven publishers, 2001, 2511–2573.
  • International Agency for Research on Cancer. IARC monographs on the evaluation on carcinogenic risks to humans. Vol. 70. Epstein-Barr virus and Kaposi's sarcoma Herpesvirus/Human Herpesvirus 8, Lyon, France: WHO IARC, 1997, 47–373.
  • Burke, A.P.; Yen, T.S.; Shekitka, K.M.; Sobin, L.H. Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction. Mod Pathol 1990, 3, 377–380.
  • Chang, M.S.; Lee, H.S.; Kim, C.W.; Kim, Y.I.; Kim, W.H. Clinicopathologic characteristics of Epstein-Barr virus-incorporated gastric cancers in Korea. Pathol Res Pract 2001, 197, 395–400. .
  • Shin, W.S.; Kang, M.W.; Kang, J.H.; Choi, M.K.; Ahn, B.M.; Kim, J.K.; Sun, H.S.; Min, K.W. Epstein-Barr virus-associated gastric adenocarcinomas among Koreans. Am J Clin Pathol 1996, 105, 174–181.
  • Chang, M.S.; Kim, W.H. Epstein-Bar virus in human malignancy: a special reference to Epstein-Barr virus associated gastric carcinoma. Cancer Res Treat 2005, 37, 257–267.
  • Lee, H.S.; Chang, M.S.; Yang, H.-K.; Lee, B.L.; Kim, W.H. Epstein-Barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison to Epstein-Barr virus-negative carcinoma. Clin Cancer Res 2004, 10, 1698–1705.
  • Chang, M.S.; Lee, H.S.; Jung, E.J.; Kim, C.W.; Lee, B.L.; Kim, W.H. Cell-cycle regulators, bcl-2 and NF-kappa B in Epstein-Barr virus-positive gastric carcinomas. Int J Oncol 2005, 27, 1265–1272.
  • Sheng, W.; Decaussin, G.; Sumner, S.; Ooka, T. N-terminal domain of BARF1 gene encoded by Epstein-Barr virus is essential for malignant transformation of rodent fibroblasts and activation of Bcl-2. Oncogene 2001, 20, 1176–1185.
  • Sheng, W.; Decaussin, G.; Ligout, A.; Takada, K.; Ooka, T. Malignant transformation of Epstein-Barr virus-negative Akata cells by introduction of the BARF1 gene carried by Epstein-Barr virus. J Virol 2003, 77, 3859–2865.
  • zur Hausen, A.; Brink, A.A.; Craanen, M.E.; Middeldorp, J.M.; Meijer, C.J.; van den Brule, A.J. Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene. Cancer Res 2000, 60, 2745–2748.
  • Baeuerle, P.A.; Baltimore, D. NF-kappa B: ten years after. Cell 1996, 87, 13–20.
  • Bours, V.; Bentires-Alj, M.; Hellin, A.C.; Viatour, P.; Robe, P.; Delhalle, S.; Benoit, V.; Merville, M.P. Nuclear factor-kappa B, cancer, and apoptosis. Biochem Pharmacol 2000, 60, 1085–1089.
  • Sonenshein, G.E. Rel/NF-kappa B transcription factors and the control of apoptosis. Semin Cancer Biol 1997, 8, 113–119.
  • Chan, H.; Bartos, D.P.; Owen-Schaub, L.B. Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappa B p50-p65 recruitment. Mol Cell Biol 1999, 19, 2098–2108.
  • Zheng, Y.; Ouaaz, F.; Bruzzo, P.; Singh, V.; Gerondakis, S.; Beg, A.A. NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death. J Immunol 2001, 166, 4949–5497.
  • Deng, J.; Miller, S.A.; Wang, H.Y.; Xia, W.; Wen, Y.; Zhou, B.P.; Li, Y.; Lin, S.Y.; Hung, M.C. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell 2002, 2, 323–334.
  • Ougolkov, A.; Zhang, B.; Yamashita, K.; Bilim, V.; Mai, M.; Fuchs, S.Y.; Minamoto, T. Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappa B in colorectal cancer. J Natl Cancer Inst 2004, 96, 1161–1170.
  • Spiegelman, V.S.; Slaga, T.J.; Pagano, M.; Minamoto, T.; Ronai, Z.; Fuchs, S.Y. Wnt/beta-catenin signaling induces the expression and activity of beta-TrCp ubiquitin ligase receptor. Mol Cell 2000, 5, 877–882.
  • Winston, J.T.; Strack, P.; Beer-Romero, P.; Chu, C.Y.; Elledge, S.J.; Harper, J.W. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta-catenin and stimulates Ikappa Balpha ubiquitination in vitro. Genes Dev 1999, 13, 270–283.
  • Polakis, P. Wnt signaling and cancer. Genes Dev 2000, 14, 1837–1851.
  • Barth, A.; Nathke, I.; Nelson, W.J. Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathway. Curr Opin Cell Biol 1997, 9, 683–690.
  • Tetsu, O.; McCormick, F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398, 422–426.
  • Nakanishi, C.; Toi, M. Nuclear factor-kappa B inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 2005, 5, 297–309.
  • Pikarsky, E.; Ben-Neriah, Y. NF-kappa B inhibition: a double-edged sword in cancer?. Eur J Cancer 2006, 42, 779–784.
  • Inoue, J.I.; Gohda, J.; Akiyama, T.; Semba, K. NF-kappa B activation in development and progression of cancer. Cancer Sci 2007, 98, 268–274.
  • Nabais, S.; Machado, J.C.; Lopes, C.; Seruca, R.; Carneiro, F.; Sobrinho-Simoes, M. Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome. Histopathology 2002, 41, 368–369.
  • Loercher, A.; Lee, T.L.; Ricker, J.L.; Howard, A.; Geoghegen, J.; Chen, Z.; Sunwoo, J.B.; Sitcheran, R.; Chuang, E.Y.; Mitchell, J.B.; Baldwin, A.S.; Van-Waes, C.Jr Nuclear factor-κB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Res 2004, 64, 6511–6523.
  • Sun, J.; Hobert, M.E.; Duan, Y.; Rao, A.S.; He, T.C.; Chang, E.B.; Madara, J.L. Crosstalk between NF-κB and β-catenin pathways in bacterial-colonized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2005, 289, G129–G137.
  • Baeza-Raja, B.; Munoz-Canoves, P. p38 MAPK-induced NF-κB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol Biol Cell 2004, 15, 2013–2026.
  • Nelson, D.E.; Ihekwaba, A.E.; Elliott, M.; Johnson, J.R.; Gibney, C.A.; Foreman, B.E.; Nelson, G.; See, V.; Horton, C.A.; Spiller, D.G.; Edwards, S.W.; McDowell, H.P.; Unitt, J.F.; Sullivan, E.; Grimley, R.; Benson, N.; Broomhead, D.; Kell, D.B.; White, M.R. Oscillations in NFκB signaling control the dynamics of gene expression. Science 2004, 306, 704–708.
  • Han, Y.; Meng, T.; Murray, N.R.; Fields, A.P.; Brasier, A.R. IL-1 induced NF-κB IκBαautoregulatory feedback loop hepatocytes: a role for PKCα in post-transcriptional regulation of IκBα resynthesis. J Biol Chem 1999, 274, 939–947.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.