Oligonucleotide DNA Microarray Profiling of Lung Adenocarcinoma Revealed Significant Downregulation and Deletions of Vasoactive Intestinal Peptide Receptor 1

REFERENCES

• Parkin, D.M.; Bray, F.I.; Devesa, S.S. Cancer burden in the year 2000. The global picture. Eur J Cancer 2001, 37, S4–S66.
   PubMed Web of Science ®Google Scholar
• Minna, J.D.; Toth, J.A.; Gazdar, A.F. Focus on lung cancer. Cancer Cell 2002, 1, 49–52.
   PubMed Web of Science ®Google Scholar
• Schena, M.; Shalon, D.; Davis, R.W.; Brown, P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270(5235), 467–470.
   PubMed Web of Science ®Google Scholar
• Beer, D.G.; Kardia, S.L.R.; Huang, C.-C.; Giordano, T.J.; Levin, A.M.; Misek, D.E.; Lin, L.; Chen, G.; Gharib, T.G.; Thomas, D.G.; Lizyness, M.L.; Kuick, R.; Hayasaka, S.; Taylor, J.M.G.; Iannettoni, M.D.; Orringer, M.B.; Hanash, S. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002, 8(8), 816–824.
   PubMed Web of Science ®Google Scholar
• Liu, H.; Kho, A.T.; Kohane, I.S.; Sun, Y. Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development. PLoS Med 2006, 3(7), 1090–1102.
   Web of Science ®Google Scholar
• Bhattacharjee, A.; Richards, W.; Staunton, J.; Li, C.; Monti, S.; Vasa, P.; Ladd, C.; Beheshti, J.; Bueno, R.; Gillette, M.; Loda, M.; Weber, G.; Mark, E.J.; Lander, E.S.; Wong, W.; Johnson, B.E.; Golub, T.R. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Nat Acad Sci USA 2001, 98(24), 13790–13795.
   PubMed Web of Science ®Google Scholar
• Garber, M.E.; Troyanskaya, O.G.; Schluens, K.; Petersen, S.; Thaesler, Z.; Pacyna-Gengelbach, M.; van de Rijn, M.; Rosen, G.D.; Perou, C.M.; Whyte, R.I.; Altman, R.B.; Brown, P.O.; Botstein, D.; Petersen, I. Diversity of gene expression in adenocarcinoma of the lung. Proc Nat Acad Sci USA 2001, 98, 13784–13789.
   PubMed Web of Science ®Google Scholar
• Raponi, M.; Zhang, Y.; Yu, J.; Chen, G.; Lee, G.; Taylor, J.M.G.; MacDonald, J.; Thomas, D.; Moskaluk, C.; Wang, Y.; Beer, D.G. Gene expression signature for predicting prognosis of squamous cell and adenocarcinomas of the lung. Cancer Res 2006, 66(15), 7466–7472.
   PubMed Web of Science ®Google Scholar
• Stearman, R.S.; Dwyer-Nield, L.; Zerbe, L.; Blaine, S.A.; Chan, Z.; Bunn Jr, P.A.; Johnson, G.L.; Hirsch, F.R.; Merrick, D.T.; Franklin, W.A.; Baron, A.E.; Keith, R.L.; Nemenoff, R.A.; Malkinson, A.M.; Geraci, M.W. Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model. Am J Pathol 2005, 167, 1763–1775.
   PubMed Web of Science ®Google Scholar
• Powell, C.A.; Spira, A.; Derti, A.; De Lisi, C.; Liu, G.; Borczuk, A.; Busch, S.; Sahasrabudhe, S.; Chen, Y.; Sugarbaker, D.; Bueno, R.; Richards, W.G.; Brody, J.S. Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol 2003, 29, 157–162.
   PubMed Web of Science ®Google Scholar
• Jiang, F.; Yin, Z.; Caraway, N.P.; Li, R.; Katz, R.L. Genomic profiles in stage I primary non small cell lung cancer using comparative genomic hybridization analysis of cDNA microarrays. Neoplasia 2004, 6(5), 623–635.
   PubMed Web of Science ®Google Scholar
• Inamuro, K.; Shimoji, T.; Ninomiya, H.; Hiramatsu, M.; Okui, M.; Satoh, Y.; Okumura, S.; Nakagawa, K.; Noda, T.; Fukayama, M.; Ishikawa, Y.A. Metastatic signature in entire lung adenocarcinomas irrespective of morphological heterogeneity. Hum Pathol 2007, 38, 702–709.
   PubMed Web of Science ®Google Scholar
• Weir, B.A.; Woo, M.S.; Getz, G.; Perner, S.; Ding, L.; Beroukhim, R.; Lin, W.M.; Province, M.A.; Kraja, A.; Johnson, L.A.; Shah, K.; Sato, M.; Thomas, R.K.; Barletta, J.A.; Borecki, I.B.; Broderick, S.; Chang, A.C.; Chiang, D.Y.; Chirieac, L.R.; Cho, J.; Fujii, Y.; Gazdar, A.F.; Giordano, T.; Greulich, H.; Hanna, M.; Johnson, B.E.; Kris, M.G.; Lash, A.; Lin, L.; Lindeman, N.; Mardis, E.R.; McPherson, J.D.; Minna, J.D.; Morgan, M.B.; Nadel, M.; Orringer, M.B.; Osborne, J.R.; Ozenberger, B.; Ramos, A.H.; Robinson, J.; Roth, J.A.; Rusch, V.; Sasaki, H.; Shepherd, F.; Sougnez, C.; Spitz, M.R.; Tsao, M.-S.; Twomey, D.; Verhaak, R.G.W.; Weinstock, G.M.; Wheeler, D.A.; Winckler, W.; Yoshizawa, A.; Yu, S.; Zakowski, M.F.; Zhang, Q.; Beer, D.G.; Wistuba, I.I.; Watson, M.A.; Garraway, L.A.; Ladanyi, M.; Travis, W.D.; Pao, W.; Rubin, M.A.; Gabriel, S.B.; Gibbs, R.A.; Varmus, H.E.; Wilson, R.K.; Lander, E.S.; Meyerson, M. Characterizing the cancer genome in lung adenocarcinoma. Nature 2007, 450, 893–898.
   PubMed Web of Science ®Google Scholar
• Bianchi, F.; Nuciforo, P.; Vecchi, M.; Bernard, L.; Tizzoni, L.; Marchetti, A.; Buttitta, F.; Felicioni, L.; Nicassio, F.; DiFiore, P.P. Survival prediction of stage I lung adenocarcinomas by expression of 10 genes. J Clin Invest 2007, 117(11), 3436–3444.
   PubMed Web of Science ®Google Scholar
• Ein-Dor, L.; Zuk, O.; Domany, E. Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc Nat Acad Sci USA 2006, 103(15), 5923–5928.
   PubMed Web of Science ®Google Scholar
• Cleveland, W.S.; Devlin, S.J. Locally weighted regression: an approach to regresion analysis by local fitting. J Am Stat Assoc 1988, 83, 596–610.
   Web of Science ®Google Scholar
• Sreedharan, S.P.; Huang, J.-X.; Cheung, M.-C.; Goetzl, E.J. Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene. Proc Nat Acad Sci USA 1995, 92, 2939–2943.
   PubMed Web of Science ®Google Scholar
• Blaster, D.A.; O’Dorisio, M.S.; Albers, A.R.; Park, S.K.; Qualman, S.J. Suppression of tumorigenicity in neuroblastoma cells by upregulation of human vasoactive intestinal peptide receptor type 1. Regul Pept 2002, 109, 155–165.
   PubMed Web of Science ®Google Scholar
• Fruhwald, M.C.; O’Dorisio, M.S.; Fleitz, J.; Pietsch, T.; Reubi, J.C. Vasoactive intestinal peptide (VIP) and VIP receptors: gene expression and growth modulation in medulloblastoma and other central primitive neuroectodermal tumors of childhood. Int J Cancer 2002, 81, 165–173.
   Google Scholar
• Garcia-Fernandez, M.O.; Solano, R.M.; Carmena, M.J.; Busto, R.; Bodega, G.; Ruiz-Villaespesa, A.; Prieto, J.; Sanchez-Chapado, M. Expression of functional PACAP/VIP receptors in human prostate cancer and healthy tissue. Peptides 2003, 24,893–902.
   PubMed Web of Science ®Google Scholar
• Reubi, J.C.; Läderach, U.; Waser, B.; Gebbers, J.O.; Robberecht, P.; Laissue, J.A. Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin. Cancer Res 2000, 60, 3105–3112.
   PubMed Web of Science ®Google Scholar
• Maruno, K.; Absood, A.; Said, S.I. Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo. Proc Nat Acad Sci USA 1998, 95, 14373–14378.
   PubMed Web of Science ®Google Scholar
• Hung, J.; Kishimoto, Y.; Sugio, K.; Virmani, A.; McIntire, D.D.; Minna, J.D.; Gazdar, A.F. Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma. J Am Med Assoc 1995, 273, 558–563.
   PubMed Web of Science ®Google Scholar
• Denhardt, D.T.; Mistretta, D.; Chambers, A.F.; Krishna, S.; Porter, J.F.; Raghuram, S.; Rittling, S.R. Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter. Clin Exp Metastasis 2003, 20, 77–84.
   PubMed Web of Science ®Google Scholar
• Schneider, S.; Yochim, J.; Barabender, J.; Uchida, K.; Danenberg, K.D.; Metzger, R.; Scneider, P.M.; Salonga, D.; Holscher, A.H.; Danenberg, P.V. Osteopontin but not osteonectin messenger RNA expression is a prognostic marker in curatively resected non-small cell lung cancer. Clin Cancer Res 2004, 10, 1588–1596.
   PubMed Web of Science ®Google Scholar