Leukotrienes Antagonize the Antiproliferative Effect of Larrea divaricata Cav. on a Lymphoma Cell Line Interfering with cAMP Intracellular Level and PKC Activity

REFERENCES

• Anesini C, Genaro A, Cremaschi G, Sterin Borda L, Cazux C, Borda E. Immunomodulatory activity of Larrea divaricata Cav. Fitoterapia 1996;67(4):329–334.
   Google Scholar
• Anesini C, Genaro A, Cremaschi G, Boccio J, Zubillaga M, Sterin Borda L, Borda E. “In vivo” antitumor activity of Larrea divaricata Cav. Comparison of two routes of administration extract. Phytomedicine 1998;5:41–45.
   PubMed Web of Science ®Google Scholar
• Anesini C, Genaro A, Cremaschi G, Zubillaga M, Boccio J, Sterin Borda L, Borda E. “In vivo” and “in vitro” antitumoral action of Larrea divaricata Cav. Acta Physiologica Pharmacologica et Therapeutica Latinoamericana 1996;46(1):33–40.
   Google Scholar
• Anesini C, Genaro A, Cremaschi G, Sterin Borda L, Borda E. Antimitogenic effect of Larrea divaricata Cav.: participation in arachidonate metabolism. Comp Biochem Physiol Part C 1999; 122(2):245–252.
   PubMed Web of Science ®Google Scholar
• Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1988;334:661–665.
   PubMed Web of Science ®Google Scholar
• Parker PJ, Kour G, Marais RM, Mitchell F, Pears C, Schaap D, Stabel S, Webster C. Protein kinase C—a family affair. Mol Cell Endocrinol 1989;65(1–2):1–11.
   PubMed Web of Science ®Google Scholar
• Kennedy MJ, Prestigiacomo LJ, Tyler G, Mayand WS, Davidson NE. Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Cancer Res 1992;5:1278–1283.
   Google Scholar
• Kolivunen J, Aaltonen V, Peltonen J. Protein kinase C (PKC) family in cancer progression. Cancer Lett 2006;235(1):1–10.
   PubMed Web of Science ®Google Scholar
• Dumont JE, Jauniaux JC, Roger PP. The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem Sci 1989;14(2): 67–71.
   PubMed Web of Science ®Google Scholar
• Stork PJ, Schmitt JM. Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol 2002;12(6):258–266.
   PubMed Web of Science ®Google Scholar
• Van Oirschot BA, Stahl M, Lens SM, Medema RH. Protein kinase A regulates expression of p27(kip1) and cyclin D3 to suppress proliferation of leukemic T cell lines. J Biol Chem 2001;276(36): 33854–33860.
   PubMed Web of Science ®Google Scholar
• Stege P, Davicino R, Vega A, Casali Y, Correa S, Micalizzi B. Antimicrobial activity of aqueous extracts of Larrea divaricata Cav. (Jarilla) against Helicobacter pylori. Phytomedicine 2006;13(9–10):724–727.
   PubMed Web of Science ®Google Scholar
• Davicino R, Mattar A, Casali Y, Porporatto C, Correa S, Micalizzi B. Activation and apoptosis of mouse peritoneal macrophages by extracts of Larrea divaricata Cav. (Jarilla). Int Immunopharmacol 2006;13–14(6):2047–2056.
   Google Scholar
• Genaro AM, Bosca L. Early signals in alloantigen-induced B-cell proliferation. J Immunol 1993;151(4):1832–1843.
   PubMed Web of Science ®Google Scholar
• Junco, M, Diaz-Guerra MJM, Bosca L. Substrate-dependent inhibitors of protein kinase C by specific inhibitors. FEBS Lett 1990;263(1):169–174.
   PubMed Web of Science ®Google Scholar
• Diaz-Guerra MJM, Bosca L. Lack of translocation of protein kinase C from the cytosol to the membrane in vasopresin-stimulated hepatocytes. Biochem J 1990;269(1):163–176.
   PubMed Web of Science ®Google Scholar
• Jasuda I, Kishimoto A, Tanaka S, Masahiro T, Sokurai A, Nishizuka A. Synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun 1990;166(3):1220–1227.
   PubMed Web of Science ®Google Scholar
• Edgar VA, Sterin-Borda L, Cremaschi G, Genaro AM. Role of protein kinase C and cAMP in fluoxetine effects on human T-cell proliferation. Eur J Pharmacol 1999;372(1):65–73.
   PubMed Web of Science ®Google Scholar
• Shimizu T, Wolfe LS. Arachidonic acid cascade and signal transduction. J Neurochem 1990;55(1):1–15.
   PubMed Web of Science ®Google Scholar
• Vore SJ, Eling TE, Danolowicz M, Turker AN. Regulation of murine hematopoiesis by arachidonic acid metabolites. Int J Immunopharmacol 1989;11(5):435–442.
   PubMed Web of Science ®Google Scholar
• Drazen JM, Austen KF. Leukotrienes and airway responses. Am Rev Respir Dis 1987;136(4):985–998.
   PubMed Web of Science ®Google Scholar
• Ford-Hutchinson AW. Leukotriene B4 in inflammation. Crit Rev Immunol 1990;10:1–12.
   PubMed Web of Science ®Google Scholar
• El-Hakim IE, Langdon JD, Zakrzewski JT, Costello JF. Leukotriene B4 and oral cancer. Br J Oral Maxillofac Surg 1990;28(3):155–159.
   PubMed Web of Science ®Google Scholar
• Bortuzzo C, Hanif R, Kashfi K, Staiano-Coico L, Shift SJ, Rigas B. The effect of leukotrienes B and selected HETEs on the proliferation of colon cancer cells. Biochim Biophys Acta 1996;1300(3): 240–246.
   PubMed Web of Science ®Google Scholar
• Wei-Gang T, Xian-Zhong D, Talamonti MS, Bell RH, Adrian TE. LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways. Biochem Biophys Res Commun 2005;335(3):949–956.
   PubMed Web of Science ®Google Scholar
• Wei-Gang T, Xian-Zhong D, Adrian TE. The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells. Biochem Biophys Res Commun 2002;296(4): 942–948.
   PubMed Web of Science ®Google Scholar
• Wei-Gang T, Xian-Zhong D, Standop WJ, Pour PM, Adrian TE. Leukotriene B4 receptor antagonist LY293111 inhibits proliferation and induces apoptosis in human pancreatic cancer cells. Clin Cancer Res 2002;8(10):3232–3242.
   PubMed Web of Science ®Google Scholar
• Hennig R, Ventura J, Segersvard R, Ward E, Ding XZ, Rao SM, Jovanovic BD, Iwamura T, Talamonti MS, Bell Jr., RH, Adrian TE. LY293111 improves efficacy of gemcitabine therapy on pancreatic cancer in a fluorescent orthotopic model in athymic mice. Neoplasia 2005;7(4):417–425.
   PubMed Web of Science ®Google Scholar
• Ralph P. Retention of lymphocyte characteristics by mielomas and θ +- lymphomas: sensitivity to cortisol and phytohemagglutinin. J Immunol 1973;110:1470–1475.
   PubMed Web of Science ®Google Scholar
• Estes G, Solomon SS, Norton WL. Inhibition of lymphocyte stimulation by cyclic and non-cyclic nucleotides. J Immunol 1971;107:1489–1492.
   PubMed Web of Science ®Google Scholar
• Katsaros D, Tortora G, Tagliaferri P, Clair T, Ally S, Neckers L, Robins RK, Cho-Chung YS. Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth. FEBS Lett 1987;223(1):97–103.
   PubMed Web of Science ®Google Scholar
• Tortora G, Clair T, Katsaros D, Ally S, Colamonici O, Neckers LM, Tagliaferri P, Jahnsen T, Robins RK, Cho-Chung YS. Induction of megakaryocytic differentiation and modulation of protein kinase gene expression by site-selective cAMP analogs in K-562 human leukemic cells. Proc Natl Acad Sci USA 1989;86(8):2849–2852.
   PubMed Web of Science ®Google Scholar
• Cho-Chung YS. Site-selective 8-chloro-cyclic adenosine 3′,5′-monophosphate as a biologic modulator of cancer: restoration of normal control mechanisms. J Natl Cancer Inst 1989;81(13): 982–987.
   PubMed Web of Science ®Google Scholar
• Davicino R, Manuele MG, Turner S, Ferraro G, Anesini C. Antiproliferative activity of Larrea divaricata Cav. on a lymphoma cell line: participation of hydrogen peroxide in its action. Cancer Invest 2010;28(1):13–22.
   PubMed Web of Science ®Google Scholar
• Wang S, Gustafson E, Pang L, Qiao X, Behan J, Maguire M, Bayne M, Laz T. A novel hepatointestinal leukotriene B4 receptor: cloning and functional characterization. J Biol Chem 2000;275(52):40686–40694.
   PubMed Web of Science ®Google Scholar
• Sporn P, Marshall T, Peters-Golden M. Differential dependence on protein kinase C of arachidonic acid metabolism stimulated by hydrogen peroxide and zymosan in the alveolar macrophage. Biochem Biophys Acta 1990;1074(2):127–135.
   Google Scholar
• Anesini C, Ferraro G, Lopez P, Borda E. Different intracellular signals coupled to the antiproliferative action of aqueous crude extract from Larrea divaricata Cav. and nor-dihydroguaiaritic acid on lymphoma cell line. Phytomedicine 2001;8(1):1–7.
   PubMed Web of Science ®Google Scholar
• Young S, Parker PJ, Ullrich A, Stabel S. Down-regulation of protein kinase C is due to an increased rate of degradation. Biochem J 1987;244(3):775–779.
   PubMed Web of Science ®Google Scholar
• Yang YM, Wang XX, Chen JZ, Wang SJ, Hu H, Wang HQ. Resveratrol attenuates adenosine diphosphate-induced platelet activation by reducing protein kinase C activity. Am J Chin Med 2008;36(3):603–613.
   PubMed Web of Science ®Google Scholar
• Kim HY, Yu R, Kim JS, Kim YK, Sung MK. Antiproliferative crude soy saponin extract modulates the expression of IkappaBalpha, protein kinase C, and cyclooxygenase-2 in human colon cancer cells. Cancer Lett 2004;210(1):1–6.
   PubMed Web of Science ®Google Scholar
• Sánchez-Yague J, Rodríguez M, Hernandez A, Llanillo M. Inhibition of prostaglandin E2 responsive adenylcyclase in embryonal human kidney 293 cells by phorbol esthers. J Lipid Mediat Cell Signal 1995;11(1):25–39.
   PubMedGoogle Scholar