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ORIGINAL ARTICLE: CELLULAR AND MOLECULAR BIOLOGY

The Protective Effect of Cu/Zn-SOD Against Oxidative Stress After PTEN Deletion

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Pages 253-256 | Published online: 23 Feb 2011

REFERENCES

  • Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943–1947.
  • Stokoe D. PTEN. Curr Biol 2001;11:R502.
  • Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998;273:13375–13378.
  • Skrzycki M, Scibior D, Podsiad M, Czeczot H. Activity and protein level of CuZnSOD and MnSOD in benign and malignant liver tumors. Clin Biochem 2008;41:91–96.
  • Zhang Y, Zhao W, Zhang HJ, Domann FE, Oberley LW. Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth. Cancer Res 2002;62:1205–1212.
  • Oberley LW. Anticancer therapy by overexpression of superoxide dismutase. Antioxid Redox Signal 2001;3:461–472.
  • Weydert CJ, Waugh TA, Ritchie JM, Iyer KS, Smith JL, Li L, Spitz DR, Oberley LW. Overexpression of manganese or copper–zinc superoxide dismutase inhibits breast cancer growth. Free Radic Biol Med 2006;41:226–237.
  • Weydert CJ, Zhang Y, Sun W, Waugh TA, Teoh ML, Andringa KK, Aykin-Burns N, Spitz DR, Smith BJ, Oberley LW. Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth. Free Radic Biol Med 2008;44:856–867.
  • Li G, Hu Y, Huo Y, Liu M, Freeman D, Gao J, Liu X, Wu DC, Wu H. PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin. J Biol Chem 2006;281:10663–10668.
  • Liliental J, Moon SY, Lesche R, Mamillapalli R, Li D, Zheng Y, Sun H, Wu H. Genetic deletion of the PTEN tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases. Curr Biol 2000;10:401–404.
  • Sutherland MW, Learmonth BA. The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase. Free Radic Res 1997;27:283–289.
  • Li G, Robinson GW, Lesche R, Martinez-Diaz H, Jiang Z, Rozengurt N, Wagner KU, Wu DC, Lane TF, Liu X, Henninghausen L, Wu H. Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. Development 2002;129:4159–4170.
  • Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, Kornblum HI, Liu X, Wu H. Negative regulation of neural stem/progenitor cell proliferation by the PTEN tumor suppressor gene in vivo. Science 2001;294:2186–2189.
  • Wong GH, Goeddel DV. Induction of manganese superoxide dismutase by tumor necrosis factor: possible protective mechanism. Science 1988;242:941–944.
  • Ray G, Husain SA. Oxidants, antioxidants and carcinogenesis. Indian J Exp Biol 2002;40:1213–1232.
  • Yu D, Berlin JA, Penning TM, Field J. Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53. Chem Res Toxicol 2002;15:832–842.
  • Morgan C, Jenkins GJ, Ashton T, Griffiths AP, Baxter JN, Parry EM, Parry JM. Detection of p53 mutations in precancerous gastric tissue. Br J Cancer 2003;89:1314–1319.
  • Mates JM, Perez-Gomez C, Blanca M. Chemical and biological activity of free radical “scavengers” in allergic diseases. Clin Chim Acta 2000;296:1–15.
  • Adzic M, Niciforovic A, Neskovic-Konstantinovic Z, Radojcic MB. Superoxide dismutases and p53 protein levels in blood cells of breast cancer patients. J BUON 2004;9:283–287.
  • Lin Y, Kikuchi S, Obata Y, Yagyu K. Serum copper/zinc superoxide dismutase (Cu/Zn SOD) and gastric cancer risk: a case-control study. Jpn J Cancer Res 2002;93:1071–1075.
  • Liu YM, Li XD, Guo X, Liu B, Lin AH, Rao SQ. Association between polymorphisms in SOD1 and noise-induced hearing loss in Chinese workers. Acta Otolaryngol 2010;130:477–486.
  • Lahair MM, Howe CJ, Rodriguez-Mora O, McCubrey JA, Franklin RA. Molecular pathways leading to oxidative stress-induced phosphorylation of Akt. Antioxid Redox Signal 2006;8:1749–1756.
  • Lee SR, Yang KS, Kwon J, Lee C, Jeong W, Rhee SG. Reversible inactivation of the tumor suppressor PTEN by H2O2. J Biol Chem 2002;277:20336–20342.
  • Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, Downes CP. Redox regulation of PI 3-kinase signalling via inactivation of PTEN. EMBO J 2003;22:5501–5510.
  • Rojo AI, Salinas M, Martin D, Perona R, Cuadrado A. Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-κB. J Neurosci 2004;24:7324–7334.
  • Endo H, Nito C, Kamada H, Yu F, Chan PH. Reduction in oxidative stress by superoxide dismutase overexpression attenuates acute brain injury after subarachnoid hemorrhage via activation of Akt/glycogen synthase kinase-3β survival signaling. J Cereb Blood Flow Metab 2007;27:975–982.

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