15
Views
44
CrossRef citations to date
0
Altmetric
Original Article

Localization of Glutamate in Trigeminothalamic Projection Neurons: A Combined Retrograde Transport-Immunohistochemical Study

, , , &
Pages 177-190 | Published online: 10 Jul 2009

References

  • Akers R. M., Killackey H. P. Segregation of cortical and trigeminal afferents to the ventrobasal complex of the neonatal rat. Brain Res. 1979; 161: 527–532
  • Albe‐Fessard D., Berkley K. J., Kruger L., Ralston H. J., III, Willis W. D., Jr. Diencephalic mechanisms of pain sensation. Brain Res. Rev. 1985; 9: 217–296
  • Anderson P., Curtis D. R. The excitation of thalamic neurons by acetylcholine. Acta Physiol. Scand. 1964; 64: 85–99
  • Aldes L. D., Boone T. B. Organization of projections from the principal sensory trigeminal nucleus to the hypoglossal nucleus in the rat: An experimental light and electron microscopic study with axonal tracer techniques. Exp. Brain Res. 1985; 59: 16–29
  • Azerad J., Woda A., Albe‐Fessard D. Physiological properties of neurons in different parts of the cat trigeminal sensory complex. Brain Res. 1982; 246: 7–21
  • Beitz A. J. The sites of origin of brain stem neurotensin and serotonin projections to the rodent nucleus raphe magnus. J. Neurosci. 1982a; 2: 829–842
  • Beitz A. J. The nuclei of origin of brainstem enkephalin and substance P projections to the rodent nucleus raphe magnus. Neuroscience 1982b; 7: 2753–2768
  • Beitz A. J., Larson A. A., Monaghan P., Altschuler R. A., Mullett M. A., Madl J. E. Immunohistochemical localization of glutamate, glutaminase and aspartate amino‐transferase in neurons of the pontine nuclei of the rat. Neuroscience 1986; 17: 741–753
  • Bromberg M. B., Penney J. B., Jr., Stephenson B. S., Young A. B. Evidence for glutamate as the neurotransmitter of corticothalamic and corticorubral pathways. Brain Res. 1981; 215: 369–374
  • Burton H., Craig A. D., Jr. Distribution of trigeminothalamic projection cells in cat and monkey. Brain Res. 1979; 161: 515–521
  • Burton H., Craig A. D., Jr., Poulos D. A., Molt J. T. Efferent projections from temperature sensitive recording loci within the marginal zone of the nucleus caudalis of the spinal trigeminal complex in the cat. J. Comp. Neurol. 1979; 183: 753–778
  • Cechetto D. F., Standaert D. G., Saper C. B. Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat. J. Comp. Neurol. 1985; 240: 153–160
  • Craig A. D., Jr., Burton H. Spinal and medullary lamina I projection to nucleus submedius in medial thalamus: A possible pain center. J. Neurophysiol. 1981; 45: 443–466
  • Darian‐Smith I. The trigeminal system. Handbook of Sensory Physiology, Vol. 2, Somatosensory System, A. Iggo. Springer‐Verlag, Berlin 1973; 271–314
  • Dubner R., Hayes R. L., Hoffman D. S. Neural and behavioral correlates of pain in the trigeminal system. Pain, J. J. Bonica. Raven Press, New York 1980; 63–72
  • Erzurumlu R. S., Bates C. A., Killackey H. P. Differential organization of thalamic projection cells in the brain stem trigeminal complex of the rat. Brain Res. 1980; 198: 427–433
  • Fagg C. E., Foster A. C. Amino acid neurotransmitters and their pathways in the mammalian central nervous system. Neuroscience 1983; 9: 701–719
  • Falls W. M. A golgi type II neuron in trigeminal nucleus oralis: A Golgi study in the rat. Neurosci. Lett. 1983; 41: 1–7
  • Falls W. M. The morphology of neurons in trigeminal nucleus oralis projecting to the medullary dorsal horn (trigeminal nucleus caudalis): A retrograde horseradish peroxidase and Golgi study. Neuroscience 1984a; 13: 1279–1298
  • Falls W. M. Termination in trigeminal nucleus oralis of ascending intratrigeminal axons originating from neurons in the medullary dorsal horn: An HRP study in the rat employing light and electron microscopy. Brain Res. 1984b; 290: 136–140
  • Fonnum F. Glutamate: A neurotransmitter in mammalian brain. J. Neurochem. 1984; 42: 1–11
  • Fonnum F., Storm‐Mathisen J., Divac I. Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain. Neuroscience 1981; 6: 863–873
  • Fukushima T., Kerr F. W.L. Organization of trigeminothalamic tracts and other thalamic afferent systems of the brainstem in the rat: Presence of gelatinosa neurons with thalamic connections. J. Comp. Neurol. 1979; 183: 169–184
  • Greenamyre J. T., Young A. B., Penney J. B. Quantitative autoradiographic distribution of L‐[3H] glutamate binding sites in rat central nervous system. J. Neurosci. 1984; 4: 2133–2144
  • Halpain S., Wieczorek C. M., Rainbow T. C. Localization of L‐glutamate receptors in rat brain by quantitative autoradiography. J. Neurosci. 1984; 4: 2247–2258
  • Hayashi H., Sumino R., Sessle B. J. Functional organization of trigeminal subnucleus interpolaris: Nociceptive and innocuous afferent inputs, projections to thalamus, cerebellum, and spinal cord, and descending modulation from periaqueductal gray. J. Neurophysiol. 1984; 51: 890–905
  • Hockfield S., Gobel S. Neurons in and near nucleus caudalis with long ascending projection axons demonstrated by retrograde labeling with horseradish peroxidase. Brian Res. 1978; 139: 333–339
  • Hockfield S., Gobel S. An anatomical demonstration of projections to the medullary dorsal horn (trigeminal nucleus caudalis) from rostral trigeminal nuclei and the contralateral caudal medulla. Brain Res. 1982; 252: 203–211
  • Huerta M. F., Frankfurter A., Harting J. K. Studies of the principal sensory and spinal trigeminal nuclei of the rat: Projections to the superior colliculus, inferior olive, and cerebellum. J. Comp. Neurol. 1983; 220: 147–167
  • Huerta M. F., Hashikawa T., Gayoso M. J., Harting J. K. The trigemino‐olivary projection in the cat: Contributions of individual subnuclei. J. Comp. Neurol. 1985; 241: 180–190
  • Ikeda M., Tanami T., Matsushita M. Ascending and descending connection of the trigeminal sensory nuclei in the cat: A study with the retrograde and anterograde horseradish peroxidase technique. Neuroscience 1984; 12: 1243–1260
  • Jacobson S., Trojanowski J. Q. Corticothalamic neurons and thalamocortical terminal fields: An investigation in rat using horseradish peroxidase and autoradiography. Brain Res. 1975; 85: 385–401
  • Jacquin M. F., Mooney R. D., Rhoades R. W. Morphology, response properties, and collateral projections of trigeminothalamic neurons in brainstem subnucleus interpolaris of rat. Exp. Brain Res. 1986; 61: 457–468
  • Kirkpatrick D., Kruger L. Physiological properties of neurons in the principal trigeminal nucleus in the cat. Exp. Neurol. 1975; 48: 664–690
  • Kruger L. Functional subdivision of the brainstem sensory trigeminal nuclear complex. Advances in Pain Research and Therapy, J. J. Bonica, D. G. Albe‐Fessard. Raven Press, New York 1979; Vol. 3: 197–209
  • Lund R. D., Webster K. E. Thalamic afferents from the spinal cord and trigeminal nuclei: An experimental anatomical study in the rat. J. Comp. Neurol. 1967; 130: 313–328
  • Madl J. E., Larson A. A., Beitz A. J. Monoclonal antibody specific for carbodiimide‐fixed glutamate: Immunocytochemical localization in the rat CNS. J. Histochem. Cytochem. 1986; 34: 317–326
  • Magnusson K. R., Beitz A. J., Larson A. A., Madl J. E., Altschuler R. A. Immunohistochemical localization of glutamate, glutaminase, and aspartyl aminotransferase neurons in the spinal trigeminal nucleus of the rat. Soc. Neurosci. Abstr. 1985; 11: 579
  • Magnusson K. R., Larson A. A., Madl J. E., Altschuler R. A., Beitz A. J. Co‐localization of fixative‐modified glutamate and glutaminase in neurons of the spinal trigeminal nucleus of the rat: An immunohistochemical and immunoradiochemical analysis. J. Comp. Neurol. 1986a; 247: 477–490
  • Magnusson K. R., Larson A. A., Madl J. E., Beitz A. J. Combined retrograde transport‐immunohistochemical localization of glutamatergic trigeminothalamic and trigemino‐spinal projection neurons. Anat. Rec. 1986b; 214: 81A
  • Matsushita M., Ikeda M., Okado N. The cells of origin of the trigeminothalamic, trige‐minospinal and trigeminocerebellar projections in the cat. Neuroscience 1982; 7: 1439–1454
  • Mosso J. A., Kruger L. Receptor categories represented in spinal trigeminal nucleus caudalis. J. Neurophysiol. 1973; 36: 472–488
  • Olszewski J. On the anatomical and functional organization of the spinal trigeminal nucleus. J. Comp. Neurol. 1950; 92: 404–413
  • Ottersen O. P., Storm‐Mathisen J. Neurons containing or accumulating transmitter amino acids. Handbook of Chemical Neuroanatomy, Vol. 3, Classical Transmitters and Transmitter Receptors in the CNS, Part II, A. Bjorklund, T. Hokfelt, M. J. Kuhar. Elsevier, New York 1984; 141–246
  • Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. Academic Press, New York 1982
  • Peschanski M. Trigeminal afferents to the diencephalon in the rat. Neuroscience 1984; 12: 465–487
  • Price D. D., Dubner R., Hu J. W. Trigeminothalamic neurons in nucleus caudalis responsive to tactile, thermal, and nociceptive stimulation of monkey's face. J. Neurophysiol. 1976; 39: 936–953
  • Ruggiero D. A., Ross C. A., Reis D. J. Projections from the spinal trigeminal nucleus to the entire length of the spinal cord in the rat. Brain Res. 1981; 225: 225–233
  • Rye D. B., Saper C. B., Wainer B. H. Stabilization of the tetramethylbenzidine (TMB) reaction product: Application for retrograde and anterograde tracing, and combination with immunohistochemistry. J. Histochem. Cytochem. 1984; 32: 1145–1153
  • Shigenaca Y., Nakatani Z., Nishimori T., Suemune S., Kuroda R., Matano S. The cells of origin of cat trigeminothalamic projections: Especially in the caudal medulla. Brain Res. 1983; 277: 201–222
  • Shigenaga Y., Okamoto T., Nishimori T., Suemune S., Nasution I. D., Chen I. C., Tsuru K., Yoshida A., Tabuchi K., Hosoi M., Tsuru H. Oral and facial representation in the trigeminal principal and rostral spinal nuclei of the cat. J. Comp. Neurol. 1986; 244: 1–18
  • Shigenaga Y., Takabake M., Sugimoto T., Sakai A. Neurons in marginal layer of trigeminal nucleus caudalis projecting to ventro‐basal complex (VB) and posterior nuclear group (PO) demonstrated by retrograde labeling with horseradish peroxidase. Brain Res. 1979; 166: 391–396
  • Silverman J. D., Kruger L. Projection of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport. Brain Res. 1985; 361: 383–388
  • Somers D., Panneton W. M. Heterogeneity of neurons in the subnucleus interpolaris of the cat. Brain Res. 1984; 309: 335–340
  • Tracey D. J. Somatosensory system. The Rat Nervous System Vol. 2, Hindbrain and Spinal Cord, G. Paxinos. Academic Press, New York 1985; 129–152
  • Wainer B. H., Rye D. B. Retrograde horseradish peroxidase tracing combined with localization of choline acetyltransferase immunoreactivity. J. Histochem. Cytochem. 1984; 32: 439–443
  • Walker J. E., Fonnum F. Regional cortical glutamatergic and aspartergic projections to the amygdala and thalamus of the rat. Brain Res. 1983; 267: 371–374
  • Yokota T., Nishikawa N. Reappraisal of somatotopic tactile representation within trigeminal subnucleus caudalis. J. Neurophysiol. 1980; 43: 700–712
  • Yokota T., Nishikawa N., Nishikawa Y. Trigeminal nociceptive neurons in the trigeminal subnucleus caudalis and bulbar lateral reticular formation. Advances in Pain Research and Therapy, J. J. Bonica, D. G. Albe‐Fessard. Raven Press, New York 1979; Vol. 3: 211–217

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.