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Research Article

Yeast Lipids: Extraction, Quality Analysis, and Acceptability

Pages 463-491 | Published online: 27 Sep 2008

References

  • Jacob Z. Recovery of lipids and proteins from yeast biomass. Yeast Biotechnology-2. Proceedings of the National Symposium on Yeast for Alcohol and Fat Production, S. C. Basappa, P. Tauro. CFTRI, Mysore 1989; 175
  • Miller Yeasts M. W. Prescott & Dunns' Industrial Microbiology, 4th ed., G. Reed. AVI Publishing, Westport, CT 1982; 15
  • Catley B. J. Isolation and analysis of cell walls. Yeast a Practical Approach, I. Campbell, J. H. Duffs. IRL Press, Oxford 1988; 163
  • Phaff H. J. Structure and biosynthesis of the yeast cell envelope. The Yeasts, A. H. Rose, J. S. Harisson. Academic Press, New York 1971; Vol. II: 135
  • Gorin P. A. J., Spencer J. F. T., Mackenzie S. L. Estimated molecular weight of amylase from the yeast. Rhodotorula peneaus, Can. J. Chem. 1966; 44: 2087
  • Gorin P. A. J., Horitsu K., Spencer J. F. T. An exocellular mannan, alternatively linked 1, 3-B and 1,4-B from. Rhodotorula glutinis, Can. J. Chem. 1965; 43: 950
  • Master L., Sikl D., Bauer S., Sandula J. Extracellular polysaccharide-protein complexes produced by. Candida albicans, Folia Microbiol. 1966; 11: 373
  • Slodki M. E. Hydrolysis products from an extracellular tremella polysaccharide. Can. J. Microbiol. 1966; 12: 495
  • Gorin P. A. J., Spencer J. F. T. A novel pentosyl-mannan arising from the yeast. Trichosporon cutaneum. Can. J. Chem. 1967; 45: 1543
  • Denobel J. G., Barnett J. A. Passage of molecules through yeast cell walls: a brief essay-review. Yeast 1991; 7: 313
  • Matile P. H., Moor H., Robinow C. F. Yeast cytology. The Yeasts, Biology of Yeasts, A. H. Rose, J. S. Harrison. Academic Press, New York 1969; Vol. I: 219
  • Duell E. A., Inoue S., Utter M. F. Isolation and properties of intact mitochondria from sphero-plasts of yeast. J. Bacteriol. 1964; 88: 1762
  • Manners D. J., Masson A. J., Patterson J. C., Bjorndall H., Lindberg B. The structure of a B-(1–3)-D-glucan from yeast cell walls. Biochem. J. 1973; 135: 19
  • Manners D. J., Masson A. J., Patterson J. C., Bjorndall H., Lindberg B. The structure of a B-(1–6)-D-glucan from yeast cell walls. Biochem. J. 1973; 135: 31
  • Northcote W. J. The structure and organization of the polysaccharides of yeast. Pure Appl. Chem. 1963; 7: 669
  • Houwink A. L., Kreger D. R. The cell wall of yeasts – electron microscope and X-ray differ-action study. Antonie van Leeuwenhoek J. Microbiol. Serol. 1953; 19: 1
  • Falcone G., Nickerson W. J. Cell-wall man-nan protein of baker's yeast. Science 1956; 124: 272
  • Fleet G. H., Phaff J. H. Glucanases in Schi-zosaccharomyces. Isolation and properties of the cell wall-associated B(l–3)-glucanases. J. Biol. Chem. 1974; 249: 1717
  • Ballou C. E. Yeast cell wall and cell surface. The Molecular Biology of Yeast Saccharomyces, J. N. Strathen, E. W. Jones, J. R. Broach. Cold Spring Harbor, New York 1982; 335
  • Wheals A. E. Biology of the cell cycle in yeasts. The Yeasts, 2nd ed., A. H. Rose, J. S. Harrison. Academic Press, New York 1987; Vol. I: 283
  • Ruinen J., Deinema M. H., Van Der Scheer C. Cellular and extracellular structures in Crypto-coccus laurentii and Rhodotorula species. Can. J. Microbiol. 1968; 14: 1133
  • Beran K. Budding of yeast cells, their scars and ageing. Adv. Microbiol. Physiol. 1968; 2: 143
  • Hunter K., Rose A. H. Yeast lipids and membranes. The Yeast Physiology and Biochemistry of Yeasts, A. H. Rose, J. S. Harrison. Academic Press, New York 1971; Vol. II: 211
  • Ratledge C., Evans C. T. Lipids and their metabolism. The Yeasts. Metabolism and Physiology of Yeasts, 2nd ed., A. H. Rose, J. S. Harrison. Academic Press, New York 1989; Vol. 3: 367
  • Rattray J. B. M. Yeasts. Microbial lipids, C. Ratledge, S. G. Wilkinson. Academic Press, New York 1988; Vol. 1: 555
  • Rose A. H., Veazey F. J. Membranes and lipids of yeasts. Yeast a Practical Approach, I. Campbell, J. H. Duffus. IRL press, Oxford 1988; 255
  • Carman G. M. Phospholipid biosynthesis in yeast. Ann. Rev. Biochem. 1989; 58: 635
  • Bloch K. Sterol structure and membrane function. Crit. Rev. Biochem. 1989; 14: 47
  • Woodbine M. Microbial fat: microorganisms as potential fat producers. Prog. Ind. Microbiol. 1959; 1: 181
  • Marchant R., Smith D. G. Membraneous structures in yeasts. Camb. Philos. Soc. Biol. Rev. 1968; 43: 459
  • Letters R. Aspects of yeast metabolism. Phospholipids of yeasts, A. K. Mills. Blackwell Scientific, Oxford 1968; 303
  • Henry S. A. Membrane lipids of yeasts: biochemical and genetic studies. Molecular Biology of the YeastSaccharomyces, J. N. Strathern, E. W. Jones, J. R. Broach. Coldspring Harbor, New York 1982; 101
  • Vitols E., North R. J., Linnane A. W. Studies on the dative metabolism of Saccharomyces cervisiae. I. Observations on the fine structure of the yeasts cell. J. Biophys. Biochem. Cytol. 1961; 9: 689
  • Nuriminen T., Suomalainen H. Occurrence of long chain fatty acids and glycolipids in the cell envelope fraction of baker's yeasts. Biochem. J. 1971; 125: 963
  • Heinz E., Tulloch A. P., Spencer J. F. T. Stereospecific hydroxylation of long chain compounds by a species of. Torulopsis, J. Biol. Chem. 1969; 244: 882
  • Fulco A. J. Chain elongation, 2-hydroxylation and decarboxylation of long chain fatty acids by yeasts. J. Biol. Chem. 1967; 242: 3608
  • Law S. W. T., Burton D. N. Lipid metabolism in Achlya: changes in lipid composition during development. Can. J. Microbiol. 1976; 22: 1716
  • Viljoen B. D., Kock J. L. F., Lategan P. M. Fatty acid composition as a guide to the classification of selected genera of yeasts belonging to the Endo-mycetales. J. Gen. Microbiol. 1986; 132: 2397
  • Smit E. J., Westhuizen J. P. T., Kock J. L. F., Lategan A. Yeast identification method: the influence of culture on the cellular long chain fatty acid composition of three selected Basidiomycetous yeasts. Syst. Appl. Microbiol. 1987; 10: 38
  • Viljoen B. D., Kock J. L. F., Muller H. B., Lategan P. M. Long chain fatty acids of some sporogenous yeasts and their respective ascosporo-genous state. J. Gen. Microbiol. 1987; 133: 1019
  • Smit E. J., Kock J. L. F., Vanderwe J. P., Britz T. J. Taxonomic relationships of Cryptococ-cus and Tremetta based on fatty acid composition and otherphenotypic characters, 7. Gen. Microbiol. 1988; 134: 2849
  • Keith A. D., Wiesieski B. J., Henry S., Williams J. C. Membranes of yeast neurospora: lipid mutants and physical studies. Lipids and Bio-membranes of Eukaryotic Microorganisms, J. A. Erwin. Academic Press, New York 1973; 259
  • Rattray B. M., Schibeci A., Kidby D. K. Lipids of yeasts. Bacteriol. Rev. 1975; 39: 197
  • Watson K., Sertoli E., Griffiths D. E. Phase transitions in yeast mitochondrial membranes. The transition temperatures of succinic dehydrogenase and Fl-ATPase in mitochondria of aerobic and anaerobic cells. FEBS Lett. 1973; 30: 120
  • Bertoli E., Chapman D., Griffiths D. E., Strach S. J. Organization of yeast mitochondrial membranes fluidity and phase transition studied by colorimetry and spin label methods. Biochem. Soc. Trans. 1974; 2: 964
  • Lanyi J. K., Plachy W. Z., Kates M. Lipid interactions in membranes of extremely halophilic bacteria. II. Modification of the bilayer structure by squalene. Biochemistry 1974; 13: 4914
  • Fedele E., Jacini G. Lipid composition of vegetable oils. Adv. Lipid Res. 1971; 9: 335
  • Suzuki T., Hasegawa K. Lipid molecular species of. Lipomyces starkeyi, Agric. Biol. Chem. 1974; 38: 1371
  • Nurminen T., Konttinek S., Suomalainen H. Neutral lipids in cells and cell envelope fractions of aerobic bakers yeast and anaerobic brewer's yeast. Chem. Phys. Lipids 1975; 15
  • Yoon S. H., Rhee J. S. Quantitative physiology of Rhodotorula graciliis for microbial lipid production. Process. Biochem. 1983; 18: 2
  • Yoon S. H., Rhee J. S. Lipid from yeast fermentation: effects of cultural conditions on lipid production and its characteristics of. Rhodotorula glutinis, J. Am. Oil Chem. Soc 1983; 60: 1281
  • Suzuki T., Hasegawa K. Variations in the lipid composition and in the lipid molecular species of Lipomyces starkeyi cultivated in the glucose sufficient and deficient media. Agric. Biol. Chem. 1974; 38: 1485
  • Johnson B., Brown C. M. A possible relationship between the fatty acid composition of yeasts and the peptide mutation. Antonie van Leeuwenhoek J. Microbiol. Serol. 1972; 38: 137
  • Thorpe R. F., Ratledge C. Fatty acid distribution in triglycerides of yeasts grown on glucose or n-alkanes. J. Gen. Microbiol. 1972; 72: 151
  • Bracco U., Horisberger M., Horman I., Viani R. Lipidic fractions in yeasts and bacteria. Riv. Ital. Sostanze Grasse 1971; 48: 242
  • Ng K. H., Laneelle M. A. Lipids of the yeast. Hansenula anomala, Biochimie 1977; 59: 97
  • Chopra A., Khuller G. K. Lipid metabolism in fungi. Crit. Rev. Microbiol 1984; 11: 209
  • Smith S. W., Lester R. L. Inositol phos-phorylceramide, a novel substance and the chief member of a major group of yeast sphingolipids containing a single inositol phosphate. J. Biol. Chem. 1974; 249: 3395
  • Angus W. W., Lester R. L. Turn over of inositol and phosphorus containing lipids in Saccha-romyces cervisiae: extracellular accumulation of gly-cerophosphoenositol derived from phosphatidyl inositol. Arch. Biochem. Biophys. 1972; 151: 483
  • Steiner M. R., Lester R. L. In vitro studies of phospholipid biosynthesis in. Saccharomyces cervisiae, Biochim. Biophys. Acta 1972; 260: 222
  • Bergelson L. D., Vaver V. A., Prokazova N. V., Ushakov A. N., Popkova G. A. Diol lipids. Biochim. Biophys. Acta 1966; 116: 511
  • Tyorinoja K., Nurminen T., Suomalainen H. The cell envelope glycolipids of baker's yeast. Biochem. J. 1974; 141: 133
  • Braud J., Maurice A., Napias C. Composition et repartition des lipides au sein des cellules de. Saccharomyces cervisiae, Bull. Soc. Biol. 1970; 52: 421
  • Tulloch A. P., Spencer J. F. T. Extracellular glycolipids of Rhodotorula species. The isolation and synthesis of 3-D-hydroxypalmitic and 3-D-hydrox-ystearic acids. Can. J. Chem. 1964; 42: 830
  • Stodola F. H., Deinema M. H., Spencer J. E. T. Extracellular lipids of yeasts. Bacterid. Rev. 1967; 31: 194
  • Hootman U., Bisping B., Rhem H. J. Physiology of polyol formation by free and immobilized cells of the esmotolerant yeast. Pichiafarinosa, Appl. Microbiol. Biotechnol. 1991; 35: 258
  • Ninet L., Renaut J. Microbial Technology, 2nd ed., H. J. Peppier, D. Perlman, 1979; Vol. I: 529
  • Goodwin T. W. The biochemistry of carotenoids. Plants, 2nd eds. Chapman and Hall, New York 1980; Vol. I
  • Andrewes A. G., Phaff H. J., Starr M. P. Carotenoids of Phaffia rhodozyma, a red-pigmented fermenting yeast. Phytochemistry 1976; 15: 1003
  • Rehm H. J., Hortmann L., Reiff I. Regulation of the formation of fatty acids at the microbial oxidation of alkanes. Acta. Biotech. 1983; 3: 279
  • Buhler M., Schindler J. Biotechnology, H. J. Rehm, G. Reed. VCH Ver-lagsgesellschaft, Weinheim 1984; Vol. 6A: 329
  • White M. J., Hammond R. C., Rose A. H. Production of long-chain alcohols by yeasts. J. Gen. Microbiol. 1987; 133: 2181
  • Weete J. D. Lipid Biochemistry of Fungi and Other Organisms. Plenum Press, New York 1980
  • Guerzoni M. E., Lambertini P., Lercker G., Marchetti R. Observation preliminaires sur l'accumulation d'hydrocarbures chez Candida stea-tolytica: relation avec la synthise des lipides. Can. J. Microbiol. 1985; 31: 620
  • Dunphy P. J., Kerr J. D., Pennock J. F., Whittle K. J., Feeney J. The plurality of long chain isoprenoid alcohols (polyprenols) from natural sources. Biochim. Biophys. Acta 1967; 136: 136
  • Batrakov S. G., Panosyan A. G., Konova I. V., Bergelson L. D. Diol lipids. XXVI. Identification of a threo-butane-2,3-diol phospholipid from. Actinomyces olivaceus, Biochim. Biophys. Acta 1974; 337: 29
  • Suzuki T., Hasegawa K. Structure of hex-adecenoic acid and octadecenoic acid. Agric. Biol. Chem. 1974; 38: 2269
  • Finnerty W. R. The application of hydrocarbon utilizing microorganisms for lipid production. Biotechnology for the Oils and Fats Industry, C Ratledge, P. Dawson, B. M. Rattray. AOCS Monogr. 1984; 11: 199
  • Finnerty W. R., Singer M. E. Microbial enhancement of oil recovery. Biotechnology 1983; 1: 47
  • Parielleux A. Hydrocarbon assimilation by Candida lipolytica: formation of a biosurfactant; effects on respiratory activity and growth. Eur. J. Appl. Microbiol. Biotechnol. 1979; 8: 91
  • Boloy A. P., Loginova T. M., Tyurin V. S., Golobov A. D. Prikl. Biokhim. Microbiolog. 1983; 19: 82, (int. ed.).
  • Iguchi T., Takeda I., Ohsawa H. Emulsifying factor of hydrocarbon produced by hydrocarbon-assimilating yeast. Agric. Biol. Chem. 1969; 33: 1657
  • Tulloch A. P., Spencer J. F. T., Dienema M. H. A new hydroxy fatty acids sophoroside from. Candidabogoriensis, Can. J. Chem. 1968; 46: 345
  • Demi G., Anke T., Oberwinkler F., Giannetti B. M., Steglich W. Schizonellin A and B, new glycolipids from. Schizonella melanogramma, Phytochemistry 1980; 19: 83
  • Kawashima H., Nakahara T., Oogaki M., Tabuchi T. Extracellular production of mannosyl-erythritol lipid of mutant of Candida sp. from n-alkanes and triacylglycerols. J. Ferment. Technol. 1983; 61: 143
  • Fujii T., Tonomura K. Fatty acids extracel-lularly produced by a Candida sp. grown on ethanol. Agric. Biol. Chem. 1971; 35: 1188
  • Tulloch A. P., Spencer J. F. T. Fermentation of long chain compounds by Torulopsis apicola. IV. Products from esters and hydrocarbons with 14 and 15 carbon atoms and from the methyl palmitoleate. Can. J. Chem. 1968; 40: 1523
  • Tulloch A. P., Hill A., Spencer J. F. T. A new type of macrocyclic lactone from. Torulopsis ap-icola, Chem. Commun. 1967; 12: 584
  • Gobbert U., Lang S., Wagner F. Sophorose lipid formation by resting cells of. Torulopsis bom-bicola, Biotechnol. Lett. 1984; 6: 225
  • Lang S., Wagner F. Structure and properties of biosurfactants. Biosurfactants and Biotechnology, N. Kosaric, W. L. Cairns, N. C. C Gray. Marcel Dekker, New York 1987; 21
  • Hommel R. DD-WP 2692598,08.11.1984 (cross reference Haiferburg, D., Hommel, R., Claus, R., and Kleber, H. P.), Extracellular Microbial Lipids as Biosurfactants. Adv. Biochem. Eng.–Biotechnol. 1984; 33: 53, 1986
  • Inoue S., Ito S. Sophorolipids from Torulopsis bombicola as microbial surfactants in alkane fermentation. Biotechnol. Lett. 1982; 4: 3
  • Cooper D. G., Paddock D. A. Production of a biosurfactant from. Torulopsisbombicola, Appl. Environ. Microbiol. 1984; 47: 173
  • Spencer J. F. T. US-P. 3445337, 1969, 20.05.1969; Haferburg, D., Hommel, R., Claus, R., and Kleber, H. P., Extracellular microbial lipids as biosurfactants, Adv. Biochem. Eng.–Biotechnol., 33, 53, 1986
  • Roy P. K., Singh H. D., Bhagat S. D., Baruah J. N. Characterization of hydrocarbon emulsification and solubilization occurring the growth of Endomycopsis lipolytica on hydrocarbons. Biotechnol. Bioeng. 1979; 21: 955
  • Tulloch A. P., Hill A., Spencer J. F. T. Structure and reactions of lactonic and acidic sopho-rosides of 17-hydroxyoctadecanoic acid. Can. J. Chem. 1968; 46: 3337
  • Cirigliand M. C., Carman G. M. Isolation of a bioemulsifier from. Candida lipolytica, Appl. Environ. Microbiol. 1984; 48: 747
  • Tulloch A. P., Spencer J. F. T. Extracellular glycolipids of Rhodotorula species. The isolation and synthesis of 3-D-hydroxypalmitic and 3-D-hydrox-ystearic acids. Can. J. Chem. 1964; 42: 830
  • Shiio I., Uchio R. Microbial production of long-chain dicarboxylic acids from n-alkanes. I. Screening and properties of microorganisms producing dicarboxylic acids. Agric. Biol. Chem. 1971; 35: 2033
  • Spencer J. F. T., Spencer D. M. Economic Microbiology, A. H. Rose. Academic Press, New York 1979; Vol. II: 523
  • Kappeli O., Fiechter A. Component from the cell surface of the hydrocarbon utilizing yeast Candida tropicalis with possible relation to hydrocarbon transport. J. Bacteriol. 1917; 131
  • Cooper D. G., Zajic J. E. Surface active compounds from microorganisms. Adv. Appl. Microbiol. 1980; 26: 229
  • Kossaric N., Cairns W. L., Gray N. C. C. Biotechnology and surfactants. Biosurfactants and Biotechnology. Marcel Dekker, New York 1987; 1
  • Zajic J. E., Saffens W. Biosurfactants, Crit. Rev. Biotechnol. 1984; 1: 87
  • Zajic J. E., Panchal C. J. Bioemulsifiers. Crit. Rev. Microbiol. 1976; 5: 39
  • Folch J., Lees M. and Sloanley Stanley, G. H., A simple method for the isolation of total lipids from animal tissues. J. Biol. Chem. 1957; 226: 497
  • Bligh E. G., Dyer W. J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol 1959; 37: 911
  • Jacob Z., Priyaddarshini S. R. B., Misra M. C., Upadhayay S. N. Some aspects of recovery of oils and fats from the yeast Rhodotorula gracilis CFR-1. Proc. Symp. Semin. Recent Advances in Biochemical Engineering. BHU, Varanasi February 16 to 18, 1989
  • Ratledge C. Microbial oils and fats: an assessment of their commercial potential. Prog. Ind. Microbiol. 1982; 16: 119
  • Moreton R. S. Physiology of lipid accumulating yeasts. Single cell oil, R. S. Moreton. Longman, copublished with John Wiley & Sons, New York, New York 1988; 1
  • Bagchi S., Dutta J. Methods for yeast lipid extraction. J. Ind. Chem. Soc 1979; 56: 726
  • Letters R., Snell B. K. The structure of a lysophosphatidylcholine. J. Chem. Soc 1963; 5127
  • Zhukov A. V., Vereshchagin A. G. Current techniques of extraction, purification and preliminary fractionation of polar lipids of neutral origin. Adv. Lipid Res. 1981; 18: 247
  • Suzuki T., Takigawa A., Hasegawa K. Lipid extraction methods for. Lipomyces starkeyi, Agric. Biol. Chem. 1973; 37: 2653
  • Sobus M. T., Holmlund C. E. Extraction of lipids from yeast. Lipids 1976; 11: 341
  • Fung B. Some effects of selected hypocholester-emic compounds on yeast growth and lipid metabolism, Masters thesis. University of Maryland, College Park 1973; 27, (cross reference 116. Sobus, M. T. and Holmund, C. E., Lipids, 11, 341, 1976)
  • Deierkauf F., Booiji H. Changes in the phosphate pattern of yeast cells in relation to active carbohydrate transport. Biochim. Biophys. Acta 1968; 150: 214
  • Pedersen T. A. Lipid formation in Cryptococcus terricolus. III. Extraction and purification of lipids. Acta Chem. Scand. 1962; 16: 374
  • Letters R. Phospholipids of yeast. II. Extraction, isolation and characterization of yeast phospholipids. Biochim. Biophys. Acta 1966; 16: 489
  • Itoh T., Kaneko H. Yeast lipid in species variations. I. Simple method for estimating the cellular lipids. Yakagaku 1976; 23: 350
  • Wix P., Hopton J. W. A semi-micro method of fat extraction. Chem. Ind. (Rev.) 1957; 805
  • Hopton J. W., Woodbine M. Fat synthesis by yeasts. I. A comparative assessment of Hansenula species. J. Appl. Bacteriol. 1960; 23: 283
  • Maclean S. I., Hoffert D. The carbohydrate and fat metabolism in yeast. III. The nature of intermediate stages. Biochem. J. 1926; 20: 343
  • Shigyo F., Takeuchi M. Fat in yeast grown hydrocarbon substrates. II. Complete extraction and separation of lipids. Nippon Nogeikagaku Kaishi 1972; 46: 27
  • AOCS methods of Analysis, 3rd ed. 1970; 214
  • Starkey R. L. Lipid production by a soil yeast. J. Bacteriol. 1946; 51: 33
  • Botham P. A., Ratledge C. A biochemical explanation for lipid accumulation in Candida 107 and other oleaginous yeasts. J. Gen. Microbiol. 1979; 114: 361
  • Wingard M. R., Shand W. C. The determination of the rate of extraction of crude lipids from oil seeds with solvent. J. Am. Oil Chem. Soc. 1949; 26: 422
  • Maclean S. I. The conditions influencing the formation of fat by the yeast cell. Biochem. J. 1922; 26: 370
  • Jacob Z. Selective medium for the production of lipids by Rhodotorula gracilis CFR-1. J. Food Sci. Technol. 1988; 25: 373
  • Gill C. O., Hall M. J., Ratledge C. Lipid accumulation in an oleaginous yeast (Candida 107) growing on glucose in single-stage continuous culture. Appl. Environ. Microbiol. 1977; 33: 231
  • Moreton R. S. Yeast lipid estimation by enzymatic and nuclear magnetic resonance methods. Appl. Environ. Microbiol 1989; 55: 3009
  • Kaneko H., Hososhara M., Tanaka M., Itoh T. Lipid composition of 30 species of yeast. Lipids 1976; 11: 837
  • Moon N. J., Hammond E. G. Oil production by fermentation of lactose and the effect of temperature on the fatty acid composition. J. Am. Oil Chem. Soc 1978; 55: 683
  • Fedotkin I. M., Bugaeva O. P., Banashek V. E. Recovery of fats from biomass by extraction with fluoroalkanes (transl). Izv. Vyssh. Uchenbn. Zaved. Pishch. Tekhnol. 1987; 6: 46
  • Ratledge C., Wilkinson S. G. Microbial Lipids, C. Ratledge, S. G. Wilkinson. Academic Press, New York 1988; Vol. 1: 123
  • Hara A., Radin N. S. Lipid extraction of tissues with a low-toxicity solvent. Anal. Biochem. 1978; 90: 420
  • Saunders R. D., Horrocks L. A. Simultaneous extraction and preparation for high-performance liquid chromatography of prostaglandins and phospholipids. Anal. Biochem. 1984; 143: 71
  • Bailey R. B., Parks L. W. Potassium translocation in yeast mitochondria and its relationship to ergosterol biosynthesis. J. Bacteriol. 1975; 122: 606
  • Gonzales R. A., Parks L. W. Acid stabilization of sterols for extraction from yeast. Biochim. Biophys. Acta 1977; 489: 507
  • Taylor F. R., Parks L. W. An assessment of the specificity of sterol uptake and esterification in. Saccharomyces cervisiae, J. Biol. Chem. 1981; 256: 13048
  • Mannikin D. E., O'Donnell A. G., Goofellow M., Alderson T., Athalye M., Sachaal A., Parlett J. H. J. Microbiol. Methods 1984; 2: 233
  • Arima K., Kakinuma A., Tamura G. Sur-factin, a crystalline peptidelipid surfactant produced by Bacillus subtilis: isolation, characterization and its inhibition of fibrin clot formation. Biochem. Biophys. Res. Commun. 1968; 31: 488
  • Syldatk C., Wagner F. Production of bio-surfactants. Biosurfactants and Biotechnology, N. Kosaric, W. L. Cairns, N. C. C Gray. Marcel Decker, New York 1987; 89
  • Adams B. G., Parks L. W. Isolation from yeast of a metabolically active water-soluble form of ergosterol. J. Lipid Res. 1968; 9: 8
  • Ratledge C., Evans C. T. The yeasts. Metabolism and Physiology of Yeasts, 2nd ed., A. H. Rose, J. S. Harrison. Academic Press, New York, Vol. 3: 367
  • Ratledge C., Wilkinson S. G. An overview of microbial lipids. Microbial lipids, C. Ratledge, S. G. Wilkinson. Academic Press, New York 1988; Vol. I: 3
  • Tinoco J., Miljanich P., Lyman. Stability of lipids in lyophilized rat livers. J. Lipid Res. 1963; 4: 359
  • Zbukov A. V., Vereshchagin A. G. Apparatus for the quantitative extraction of lipids from plant materials. Fiziol. Rast. 1974; 21: 659
  • Croteau R., Fagerson J. S. Seed lipids of the American cranberry. (Vaccinum macrocarpon), Phy-tochemistry 1968; 8: 2219
  • Kates M. Plant phospholipids and glycolipids. Adv. Lipid Res. 1970; 8: 225
  • Mys G. T., Verrips C. T., Van Gorp R. T. S. U.S. Patent. 3995066, 1976
  • Gyorgy P. U.S. Patents. 3855256, 1974, and 3762933, 1973
  • Nyns E. J., Chiang N., Wiaux A. L. Comparative lipid content of Candidalypolitica grown on glucose and on n-hexadecane. Antonie van Leeuwen-hoek 1968; 34: 197
  • Kahane E. Lipid extraction by means of an azeo-tropic mixture. Comput. Rend. 1966; 257, 1963
  • Kumagawa M., Suto K. A new process for the quantitative determination of fats and unsaponi-fiable substances in animal material, also a critique of some of the ordinary methods (i). Biochem. Z. 1908; 8: 212, (cross-reference, Chem. Abstr., 2, 2560).
  • Kahane E., Regord M. T. Extracting lipid from yeast. Ann. Nutr. Aliment. 1964; 18: 1
  • Letters R. J. Inst. Brew. 1962; 68: 318, (cross reference 120. Letter, R., Biochim. Biophys. Acta, 16, 489, 1966).
  • Hanahan D. J., Jayko M. E. The isolation of dipalmitoleyl-L-0<-glycerylphosphory]choline from yeast. A new route to (dipalmitoyl)-L0<-leci-thin. J. Am. Chem. Soc 1952; 74: 5070
  • Hussain S. S., Hardin M. M. Influence of carbohydrate and nitrogen source upon lipid production by certain yeasts. Food Res. 1952; 17: 60
  • Thakur M. S., Prapulla S. G., Karanth N. G. Microscopic observation of sudan black B staining to monitor lipid production by microbes. J. Chem. Tech. Biotecknol. 1988; 42: 129
  • Pomoshchnikova G. A., Medvedeva N. F., Levchenko Meisel M. N., Kraseitskii B. M. Use of fluorescent technique for detection and quantitative determination of lipids in cells of microorganisms. Microbiologia 1980; 50: 129
  • Fiorentini R., Anelli G., Lepidi A. A., Galoppini C. Biomass from fat byproducts. III. Lipid composition of yeast cells (transl.). Rev. Ital. Sost. Gr. 1976; 53: 102
  • Official and tentative methods of the American Oil Chemists' Society, 3rd ed. 1975
  • Paquoat C., Hautfenne A. Standard methods for the Analysis of Oils, Fats and Derivatives, 7th eds. Blackwell Scientific, Oxford 1987; 1
  • Christie W. W. Lipid analysis, 2nd eds. Pergamon Press, Oxford 1982; 1
  • Edntan P. Method for determination of the amino acid sequence in peptides. Acta Chem. Scand. 1950; 4: 283
  • Naganuma T., Uzuka Y., Tanaka K. Quantitative estimation of intracellular neutral lipids of the yeast. Lipomyces starkeyi, Agric. Biol. Chem. 1982; 46: 1213
  • Naganuma T., Uzuka Y., Tanaka K. Simple and small scale break down of yeast. Anal. Biochem. 1984; 141: 74
  • Watson K., Rose A. H. Fatty-acyl composition of the lipids of Saccharomyces cervisiae grown aerobically or anaerobically in media containing different fatty acids. J. Gen. Microbiol 1980; 117: 225
  • Ratledge C., Saxton R. K. Quantitative extraction of lipid and fatty acids from a Candida species. Anal. Biochem. 1968; 26: 288
  • Thorpe R. F., Ratledge C. Fatty acids of triglycerides and phospholipids from a thermotolerant strain of Candida tropicalis grown on n-alkanes at 30 and 40 C. J. Gen. Microbiol 1973; 78: 203
  • Engler C. R., Robinson C. W. Disruption of Candida utilis cells in high-pressure flow devices. Biotechnol. Bioeng. 1981; 23: 765
  • Pan S. C., Andreasen A. A., Koolachov P. Factors influencing fat synthesis by. Rhodotorula gracilis, Arch. Biochem. 1949; 23: 419
  • Jacob Z., Krisnamurthy M. N. Studies on physicochemical characteristics and fatty acid composition of lipids produced by a strain of Rhodotorula gracilis CFR-1. J. Am. Oil Chem. Soc 1990; 67: 642
  • Duwe H., Sonnenkalb W., Roethe K. P., Rosahl B. Destraktion von lipiden aus mikrobillen eiweissisolaten. Nahrung 1986; 30: 667
  • Linder P. The results obtained in fermentation and assimilation experiments with yeasts. Chem. Ztg. 1950; 34: 1144
  • U.K. Patents. 1501355, 1976, and 1555000, 1978 Fuji Oil Co. Ltd.
  • U.K. Patent. 1579632, 1977, Mitsui Engineering and Ship Building Co. Ltd.
  • Alexander D. G., Forster A., Farmery D. W. U.K. Patent. 1466853, 1977
  • U.K. Patent Applications. 2091985 and 2091286, 1982, CPC International Inc.
  • Moreton R. S., Clode D. M. Microbial de-saturase enzyme inhibitors and their use in a method of producing lipids, U.K. Patent Application. 8407195, 1985
  • Eur. Patent Application. 0005277, 1979, CPC International Inc.
  • Niedleman S. L., Erwin J. L. (assigned to Cetus, California) Eur. Patent. 0103408, 1984
  • Tatsumi C. T., Hashimoto Y., Terashima M., Matsuo T. (assigned to Fuji Oil, Japan) U.S. Patent. 4032405, 1977
  • Moon N. J., Hammond E. G. U.S. Patent. 4235933, 1980
  • Niedleman S. L., Geigert J. (assigned to Standard Oil, Indiana), U.S. Patent. 4404283, 1984
  • Gierhart D. L. U.S. Patent. 4485172, 1984
  • U.S. Patent. 4308350, 1981, Fuji Oil Co. Ltd.
  • Davies R. J. Yeast oil from cheese whey-process development. Single Cell Oil, R. S. Moreton. Longman, copublished with John Wiley & Sons, New York, New York 1988; 99
  • Akhinyan R. M., Erzinkyan L. A., Petrosyan L. G. Method of Determining Lipids in a Dry Yeast Biomass (transl.), U.S.S.R. Patent. 558936, 1977
  • Japanese Patents. J-59130191-A, 1984, and J-60075292, 1985
  • Muller H., Voigt B., Worbs M., Winkler F. East Germany Patent DD. 154448, 1981
  • Carlile N. J., Van Selm T. J. (assigned to Lever Brothers) U.S. Patent. 3939282, 1976
  • Wieske T., Witte I., Hannewyk J., Willems M. A. G. (assigned to Lever Brothers), U.S. Patent. 3949105, 1976
  • Frommhold K. (assigned to Lever Brothers), U.S. Patent. 3796581, 1974
  • Kattenberg H. R., Verburg C. C. (assigned to Lever Brothers), U.S. Patent. 4055679, 1977
  • Read C. B. (assigned to Lever Brothers), U.S. Patent. 3889011, 1975
  • Thakur M. S., Misra M. C., Karanth N. G. Enzymatic treatment for downstream processing of microbial oils, Abstract No. IL30. Int. Semin on Downstream Processing in Biotechnol., Calcutta, 19–21, Dec, 1991
  • Lundin H. Fat synthesis by microorganisms and possible applications in industry. J. Inst. Brew. 1950; 56: 17
  • Tornqvist E., Lundin H. Inst. Sug. J. L III 1951; 53: 23–127, (cross-reference Hunter, K. and Rose, A. H., Yeast lipids and membranes, in The Yeast. Physiology and Biochemistry of Yeasts, Vol. II, Rose A. H. and Harrison, J. S., Eds, Academic Press, New York, 1971, 211)
  • The Prevention of Food Adulteration Act 1954 and Rules, Lucknow, 12th ed. Eastern Book Company. 1990; 162
  • Specifications and Criteria for Biochemical Compounds, 3rd eds. National Academy of Sciences, Washington, DC 1972; 119
  • Food and Drug Administration. Code of Federal Regulations (CFR). U.S. Government Printing Office, Washington, DC 1989; 409

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