Solvent Selection for Whole Cell Biotransformations in Organic Media

References

• Abraham M. H. Hydrogen-bonding, XXVII. Solvation parameters for functionally substituted aromatic-compounds and heterocyclic-com-pounds, from gas-liquid-chromatographic data. J. Chromatogr. 1993a; 644: 95–139
   Web of Science ®Google Scholar
• Abraham M. H. Scales of solute hydrogen-bonding — their construction and application to physico-chemical and biochemical processes. Chem. Soc. Rev. 1993b; 22: 73–83
   Web of Science ®Google Scholar
• Abraham M. H. Hydrogen bonding. XXXI. Construction of a scale of solute effective or summation hydrogen bond-basicity. J. Phys. Org. Chem. 1993c; 6: 660–684
   Web of Science ®Google Scholar
• Abraham M. H., Andonian-Haftvan J., Hamerton I., Poole C. F., Kollie T. O. Hydrogen bonding. XXVIII. Comparison of the solvation theories of Abraham and Poole, using a new acidic gas-liquid chromatography stationary phase. J. Chromatogr. 1993; 646: 351–360
   Web of Science ®Google Scholar
• Abraham M. H., Chadha H. S., Whiting G. S., Mitchell R. C. Hydrogen bonding. XXXII. An analysis of water-octanol and water-alkane partitioning, and the logP parameter of Seiler. J. Pharm. Sci. 1994; 83: 1085–1100
   PubMed Web of Science ®Google Scholar
• Abraham M. H., Lieb W. R., Franks N. P. Role of hydrogen bonding in general anaesthesia. J. Pharm. Sci. 1991a; 80: 719–724
   PubMed Web of Science ®Google Scholar
• Abraham M. H., McGowan J. C. The use of characteristic volumes to measure cavity terms in reversed phase liquid-chromatography. Chromatographia 1987; 23: 243–246
   Web of Science ®Google Scholar
• Abraham M. H., Whiting G. S. Hydrogen-bonding. XXI. Solvation parameters for alkylaromatic hydrocarbons from gas-liquid-chromatographic data. J. Chromatogr. 1992; 594: 229–241
   Web of Science ®Google Scholar
• Abraham W. H., Whiting G. S., Doherty R. M., Shuely W. J. Hydrogen-bonding. XIII. A new method for the characterization of GLC stationary phases — the Laffort data set. JCS Perkin Trans. II 1990; 1990: 1451–1460
   Google Scholar
• Abraham M. H., Whiting G. S., Dohetty R. M., Shuely W. J. Hydrogen-bonding, XVI. A new solute solvation parameter, p2H, from gas-chromatographic data. J. Chromatogr. 1991b; 587: 213–228
   Web of Science ®Google Scholar
• Adlercreutz P., Mattiasson B. Aspects of biocatalyst stability in organic solvents. Bio-catalysis 1987; 1: 99–108
   Google Scholar
• Agudo L. C. Lipid content of Saccharomyces cerevisiae strains with different degrees of ethanol tolerance. Appl. Microbiol. Biotechnol. 1992; 37: 647–651
   Web of Science ®Google Scholar
• Anderson E., Hahn-Hägerdahl B. Bioconversions in aqueous 2-phase systems. Enzyme Microb. Technol. 1990; 12: 242–254
   PubMed Web of Science ®Google Scholar
• Bacterial Energy Transduction, C. J. Anthony. Academic Press, London 1988
   Google Scholar
• Arnold F. H. Engineering enzymes for nonaqueous solvents. TIBTech 1990; 8: 244–249
   PubMed Web of Science ®Google Scholar
• Asami K., Hanai T., Koizumi N. Dielectric properties of yeast cells: effect of some ionic detergents on the plasma membranes. J. Membr. Biol. 1977; 34: 145–156
   Web of Science ®Google Scholar
• Bar R. Phase toxicity in a water-solvent two-phase microbial system. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 147–153
   Google Scholar
• Barros M. R. A., Cabral J. M. S., Novais. Production of ethanol by immobilized Saccharomyces bayanus in an extractive fermentation system. Biotechnol. Bioeng. 1987; 29: 1097–1104
   PubMed Web of Science ®Google Scholar
• Barros M. R., Carvalho M. G. V., Garcia F. A. P., Pires E. M. V. Stability performance of Cynara cardunculus L. acid protease in aqueous-organic biphasic systems. Biotechnol. Lett. 1992; 14: 179–184
   Web of Science ®Google Scholar
• Bassetti L., Tramper J. Effect of organic solvents on growth and anthraquinone production in Morinda citrifolia cell cultures. Biocatalysis in Non-Conventional Media., J. Tramper, M. H. Vermtie, H. H. Beeftink, U. von Stockar. Elsevier, Amsterdam 1992; 617–622
   Google Scholar
• Bettmann H., Rehm H. J. Degradation of phenol by polymer entrapped microorganisms. Appl. Microbiol. Biotechnol. 1984; 20: 285–290
   Web of Science ®Google Scholar
• Bettmann H., Rehm H. J. Continuous degradation of phenol(s) by Pseudomonas putida P8 entrapped in polyacrylamide-hydrazide. Appl. Microbiol. Biotechnol. 1985; 22: 389–393
   Web of Science ®Google Scholar
• Boeren S., Laane C., Hilhorst R. Viability and activity of Flavobacterium dehydrogenans in organic solvent/culture two-liquid-phase systems. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 303–310
   Google Scholar
• Bonneau P. R., Eyer ML, Graycar T. P., Estell D. A., Jones J. B. The effects of organic solvents on wild-type and mutant subtilisin-catalysed hydropses. Bioorgan. Chem. 1993; 21: 431–438
   Google Scholar
• Bowman W. C., Rand M. J., West G. B. Textbook of Pharmacology. Blackwell, London 1968
   Google Scholar
• Brink L. E. S., Tramper J. Optimization of organic solvent in multiphase biocatalysis. Biotechnol. Bioeng. 1985; 27: 1258–1269
   PubMed Web of Science ®Google Scholar
• Brink L. E. S., Tramper J. Facilitated mass transfer in a packed-bed immobilized-cell reactor by using an organic solvent as substrate reservoir. J. Chem. Tech. Biotechnol. 1987a; 37: 21–44
   Web of Science ®Google Scholar
• Brink L. E. S., Tramper J. Design of an organic-liquid-phase/immobilized-cell reactor for the microbial epoxidation of propene. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987b; 133–146
   Google Scholar
• Brink L. E. S., Tramper J., Luyben K., Ch A. M., van't Riet K. Biocatalysis in organic media. Enzyme Microb. Technol. 1988; 10: 736–743
   Web of Science ®Google Scholar
• Brown S. W., Oliver S. G. The effect of temperature on the ethanol tolerance of the yeast. Saccharomyces uvarum. Biotechnol. Lett. 1982; 4: 269–274
   Web of Science ®Google Scholar
• Bruce L. J., Daugulis A. J. Solvent selection strategies for extractive biocatalysis. Biotechnol. Progr. 1991; 7: 116–124
   PubMed Web of Science ®Google Scholar
• Bull M. H., Bull B. S., Brailsford J. D., Korpman R. A. Decoupled bilayer theory of general anaesthesia. Prog. Anesthesiol. 1980; 2: 251–259
   Google Scholar
• Butler L. G. Enzymes in non-aqueous solvents. Enzyme Microb. Technol. 1979; 1: 253–259
   Web of Science ®Google Scholar
• Carlson R., Lundstedt T. Scope of organic synthetic reactions. Multivariate methods for exploring the reaction space. An example with the Willgerodt-Kindler reaction. Acta Chem. Scand. B. 1987; 41: 164–173
   Google Scholar
• Carlson R., Lundstedt T., Albano C. Screening of suitable solvents in organic synthesis — strategies for solvent selection. Acta Chem. Scand. B 1985; 39: 79–91
   Google Scholar
• Carlson H. N., Degn H., Lloyd D. Effects of alcohols on the respiration and fermentation of aerated suspensions of bakers yeast. J. Gen. Microbiol. 1991; 137: 2879–2883
   PubMedGoogle Scholar
• Cassells J. M., Hailing P. J. Protease-catalyzed peptide-synthesis in aqueous-organic 2-phase systems: reactant precipitation and interfacial inacti-vation. Enzyme Microb. Technol. 1990; 12: 755–759
   PubMed Web of Science ®Google Scholar
• Ceen E. G., Herrmann J. P. R., Dunnill P. Solvent damage during immobilised cell catalysis and its avoidance: studies of 11α-hydroxylation of progesterone by. Aspergillus ochraceus. Appl. Microbiol. Biotechnol. 1987; 25: 491–494
   Web of Science ®Google Scholar
• Chastrette M., Rajzmann M., Chanon M., Purcell K. F. Approach to a general classification of solvents using a multivariate statistical treatment of quantitative solvent parameters. J. Am. Chem. Soc. 1985; 107: 1–11
   Web of Science ®Google Scholar
• Chiou J.-S., Ma S.-M., Kamaya H., Ueda I. Anaesthesia cutoff phenomenon: interfacial hydrogen bonding. Science 1990; 248: 583–585
   PubMed Web of Science ®Google Scholar
• Christen M., Crout D. H. G. Enzymic reductions of beta-ketoesters using immobilised yeasts. Bioreactors and Biotransformations., G. W. Moody, P. B. Baker. Elsevier, Amsterdam 1987; 213–218
   Google Scholar
• Clarke D. J., Blake-Coleman B. C., Carr R. J. G., Calder M. R., Atkinson T. Monitoring reactor biomass. Trends Biotechnol. 1986; 4: 173–178
   Web of Science ®Google Scholar
• Corre I., Lucchini J. J., Mercier G. M., Cremieux A. Antibacterial activity of phenethyl alcohol and resulting membrane alterations. Res. Microbiol. 1990; 141: 483–497
   PubMed Web of Science ®Google Scholar
• Cramer C. J., Famini G. R., Lowrey A. H. Use of calculated quantum chemical properties as surrogates for solvatochromic parameters in structure-activity relationships. Acc. Chem. Res. 1993; 26: 599–605
   Web of Science ®Google Scholar
• Creuly C., Larroche C., Gros J.-B. Byconversion of fatty acids into methyl ketones by spores of Penicillium roquefortii in a water-organic solvent, two-phase system. Enzyme Microb. Technol. 1992; 14: 669–678
   Web of Science ®Google Scholar
• Cruden D. L., Wolfram J. H., Rogers R. D., Gibson D. T. Physiological properties of a Pseudomonas strain which grows with p-xylene in a two-phase (organic-aqueous) medium. Appl. Environ. Microbiol. 1992; 58: 2723–2729
   PubMed Web of Science ®Google Scholar
• Curry S., Lieb W. R., Franks N. P. Effects of general anaesthetics on the bacterial luciferase enzyme from Vibrio harveyi: an anaesthetic target site with differential sensitivity. Biochemistry 1990; 29: 4641–4652
   PubMed Web of Science ®Google Scholar
• Dasari G., Worth M. A., Conner M. A., Pamment N. B. Reasons for the apparent difference in the effects of produced and added ethanol on culture viability during rapid fermentations by. Saccharomyces cerevisiae. Biotechnol. Bioeng. 1990; 35: 109–122
   PubMed Web of Science ®Google Scholar
• Davey C. L., Kell D. B. The low-frequency dielectric properties of biological cells. Bioelectrochemistry: Principles and Practice, H. Berg, G. Milazzo, 1995
   Google Scholar
• Davey C. L., Markx G. H., Kell D. B. On the dielectric method of monitoring cellular viability. Pure Appl. Chem. 1993; 65: 1921–1926
   Web of Science ®Google Scholar
• De Smet M. J., Kingma J., Witholt B. The effect of toluene on the structure and permeability of the outer and cytoplasmic membranes of. Escherichia coli. Biochim. Biophys. Acta 1978; 506: 64–80
   PubMedGoogle Scholar
• De Smet M. J., Kingma J., Wynberg H., Witholt B. Pseudomonas oleovorans as a tool in byconversions of hydrocarbons: growth, morphology, and conversion characteristics in different two-phase systems. Enzyme Microb. Technol. 1983; 5: 352–360
   Web of Science ®Google Scholar
• Deetz J. S., Rozzel J. D. Catalysis by alcohol dehydrogenases in organic solvents. Bio-catalysts for Industry., J. S. Dordick. Plenum Press, London 1991; 181–191
   Google Scholar
• Deutscher M. P. Preparation of cells permeable to macromolecules by treatment with toluene: studies of transfer ribonucleic acid nucleotidyltransferase. J. Bacteriol. 1974; 118: 633–639
   PubMed Web of Science ®Google Scholar
• Applied Multivariate Analysis in SAR and Environmental Studies, J. Devillers, W. Karcher. Kluwer, Dordrecht 1991
   Google Scholar
• Dickinson R., Franks N. P., Lieb W. R. Thermodynamics of anæsthetic/protein interactions. Temperature studies on firefly luciferase. Biophys. J. 1993; 64: 1264–1271
   PubMed Web of Science ®Google Scholar
• Dickinson R., Franks N. P., Lieb W. R. Can the stereoselective effects of the anesthetic isoflurane by accounted for by lipid solubility?. Biophys. J. 1994; 66: 2019–2023
   PubMed Web of Science ®Google Scholar
• Dixon N. M., Kell D. B. The inhibition by CO2 of the growth and metabolism of microorganisms. J. Appl. Bacteriol. 1989; 67: 109–136
   PubMedGoogle Scholar
• Dordick J. S. Enzymatic catalysis in monophasic organic solvents. Enzyme Microb. Technol. 1989; 11: 194–211
   Web of Science ®Google Scholar
• Dordick J. S. Principles and applications of nonaqueous enzymology. Applied Biocatalysis., H. W. Blanch, D. S. Clark. Marcel Dekker, Basel 1991; 1–52
   Google Scholar
• Dordick J. S. Designing enzymes for use in organic solvents. Biotechnol. Progr. 1992a; 8: 259–267
   PubMed Web of Science ®Google Scholar
• Dordick J. S. Enzymic and chemoenzymatic approaches to polymer synthesis. Tibtech 1992b; 10: 287–293
   PubMed Web of Science ®Google Scholar
• Dror Y., Cohen O., Freeman A. Stabilization effects on immobilised yeast: effect of gel composition on tolerance to water miscible solvents. Enzyme Microb. Technol. 1988; 10: 273–279
   Web of Science ®Google Scholar
• Dunn W. J., III. Quantitative structure-activity relationships (QSAR). Chemometrics Intell. Lab. Syst. 1989; 6: 181–190
   Web of Science ®Google Scholar
• Efroymson R. A., Alexander M. Biodegradation by an Arthrobacter species of hydrocarbons partitioned into an organic solvent. Appl. Environ. Microbiol. 1991; 57: 1441–1447
   PubMed Web of Science ®Google Scholar
• El-Tayar N., Tsai R.-S., Testa B., Carrupt P.-A., Leo A. Partitioning of solutes in different solvent systems: the contribution of hydrogen-bonding capacity and polarity. J. Pharmaceut. Sci. 1991; 80: 590–598
   PubMed Web of Science ®Google Scholar
• Escobar L., Escamilla E. Respiratory electron transfer activity in an asolectin-isooctane reverse micellar system. Biochimie 1992; 74: 161–169
   PubMed Web of Science ®Google Scholar
• Evans P. J., Wang H. Y. Response of Clostridium acetobutylicum to the presence of mixed extractants. Appl. Biochem. Biotechnol. 1988; 17: 175–192
   Web of Science ®Google Scholar
• Famini G. R., Penski C. A., Wilson L. Using theoretical descriptors in quantitative structure activity relationships: some physicochemical properties. J. Phys. Org. Chem. 1992; 5: 395–408
   Web of Science ®Google Scholar
• Favre-Bulle O., Schouten T., Kingma J., Witholt B. Bioconversion of n-octane to octanoic acid by a recombinant Escherichia coli cultured in a two-liquid phase bioreactor. Bio/Technology 1991; 9: 367–371
   PubMed Web of Science ®Google Scholar
• Favre-Bulle O., Witholt B. Biooxidation of n-octane by a recombinant Escherichia coli in a two-liquid-phase system: effect of medium components on cell growth and alkane oxidation activity. Enzyme Microb. Technol. 1992; 14: 931–937
   Web of Science ®Google Scholar
• Favre-Bulle O., Weenink E., Vos T., Preusting H., Witholt B. Continuous bioconversion of n-octane to octanoic acid by recombinant Escherichia coli (alk+) growing in a two-liquid-phase chemostat. Biotechnol. Bioeng. 1993; 41: 263–272
   PubMed Web of Science ®Google Scholar
• Felix H. Permeabilised cells. Anal. Biochem. 1982; 120: 211–234
   PubMed Web of Science ®Google Scholar
• Felix H., Nüesch J., Werhli W. A convenient method for permeabilising the fungus. Cephalosporium acermonium. Anal. Biochem. 1980; 103: 81–86
   PubMed Web of Science ®Google Scholar
• Fendler J. H. 3. Membrane Mimetic Chemistry. John Wiley & Sons, New York 1982
   Google Scholar
• Finn R. K. Inhibitory cell products: their formation and some new methods of removal. J. Ferm. Technol. 1966; 44: 305–310
   Google Scholar
• Fitzpatrick P. A., Klibanov A. M. How can the solvent affect enzyme enantioselectivity?. J. Am. Chem. Soc. 1991; 113: 3166–3171
   Web of Science ®Google Scholar
• Flores M. V., Voget C. E., Ertola R. J. J. Permeabilization of yeast cells (Kluyveromyces lactis) with organic solvents. Enzyme Microb. Technol. 1994; 16: 340–346
   Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. Is membrane expansion relevant to anassthesia?. Nature 1981; 292: 248–251
   PubMed Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. Molecular mechanisms of general anaesthesia. Nature 1982; 300: 487–493
   PubMed Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. Mapping of general anaesthetic target sites provides a molecular basis for cutoff effects. Nature 1985a; 316: 349–351
   PubMed Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. The firefly throws light on anaesthesia. Chem. Br. 1985b; 21: 919–921
   Google Scholar
• Franks N. P., Lieb W. R. Partitioning of long-chain alcohols into lipid bilayers: implications for mechanisms of general anaesthesia. Proc. Natl. Acad. Set. USA. 1986; 83: 5116–5120
   PubMed Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. What is the molecular nature of general anaesthetic target sites. Trends Pharmacol. Sci. 1987; 8: 169–174
   Web of Science ®Google Scholar
• Franks N. P., Lieb W. R. Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367: 607–614
   PubMed Web of Science ®Google Scholar
• Freeman A., Lilly M. D. The effect of water-miscible solvents on the 1-dehydrogenase activity of free and PAAH-entrapped. Arthrobacter simplex. Appl. Microbiol. Biotechnol. 1987; 25: 495–501
   Web of Science ®Google Scholar
• Frenz J., Largeau C., Casadevall E. Hydrocarbon recovery by extraction with a biocompatible solvent from free and immobilized cultures of. Botryococcus braunii. Enzyme Microb. Technol. 1989; 11: 717–724
   Web of Science ®Google Scholar
• Fukui S., Ahmed S. A., Omata T., Tanaka A. Bioconversion of lipophilic compounds in nonaqueous solvent. Effect of gel hydrophobicity on diverse conversions of testosterone by gel-entrapped Nocardia rhodocrous cells. Eur. J. Appl. Microbiol. Biotechnol. 1980; 10: 289–301
   Google Scholar
• Fukui S., Tanaka A., Iida T. Immobilization of biocatalysts for bioprocesses in organic solvent media. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 21–41
   Google Scholar
• Garza-Ramos G., Darszon A., de Gomez-Puyou Tuena M., Gomez-Puyou A. Catalysis and thermostability of mitochondrial F1-ATPase in toluene-phospholipid-low-water systems. Biochemistry 1989; 28: 3177–3182
   PubMed Web of Science ®Google Scholar
• Gill C. O., Ratledge C. Toxicity of n-alkanes, n-alk-1-enes, n-alkan-1-ols and n-alkyl-1-bromides towards yeast. J. Gen. Microbiol. 1972; 72: 165–172
   Google Scholar
• Glajch J. L., Kirkland J. J., Squire K. M., Minor J. M. Optimization of solvent strength and selectivity for reversed-phase liquid chromatography using an interactive mixture-design statistical technique. J. Chromatogr. 1980; 199: 57–79
   Web of Science ®Google Scholar
• Goldberg S., Konis Y., Rosenberg M. Effect of cetylpyridinium chloride on microbial adhesion to hexadecane and polystyrene. Appl. Environ. Microbiol. 1990; 56: 1678–1682
   PubMed Web of Science ®Google Scholar
• Gorman L. A. S., Dordick J. S. Organic solvents strip water off enzymes. Biotechnol Bioeng. 1992; 39: 392–397
   PubMed Web of Science ®Google Scholar
• Grant E. H., Sheppard R. J., South G. P. Dielectric Properties of Biological Molecules in Solution. Oxford University Press, Oxford 1978
   Google Scholar
• Grate J. W., Abraham M. H. Solubility interactions and the design of chemically selective sor-bent coatings for chemical sensors and arrays. Sensors and Actuators B 1991; 3: 85–111
   Web of Science ®Google Scholar
• Groot W. J., van der Lans R. G. J. M., Luyben K. Ch. A. M. Technologies for butanol recovery integrated with fermentations. Process Biochem. 1992; 27: 61–75
   Web of Science ®Google Scholar
• Gupta M. N. Enzyme function in organic solvents. Eur. J. Biochem. 1992; 203: 25–32
   PubMedGoogle Scholar
• Hailing P. J. Biocatalysis in multi-phase reaction mixtures containing organic liquids. Biotechnol. Adv. 1987a; 5: 47–84
   PubMed Web of Science ®Google Scholar
• Hailing P. J. Rates of enzymic reactions in predominantly organic, low water systems. Biocatalysis 1987b; 1: 109–115
   Google Scholar
• Hailing P. J. Solvent selection for biocatalysis in mainly organic-systems: predictions of effects on equilibrium position. Biotechnol. Bioeng. 1990; 35: 691–701
   PubMed Web of Science ®Google Scholar
• Hailing P. J. Thermodynamic predictions for biocatalysis in nonconventional media: theory, tests and recommendations for experimental design and analysis. Enzyme Microb. Technol. 1994; 16: 178–206
   PubMed Web of Science ®Google Scholar
• Hamoir T., Massart D. L. Expert systems in chromatography. Adv. Chromatogr. 1993; 33: 97–145
   Web of Science ®Google Scholar
• Hampe M. J. Selection of solvents in liquid/liquid extraction according to physicochemical aspects. Ger. Chem. Eng. 1986; 9: 251–263
   Google Scholar
• Hansch C. Quantitative structure-activity relationships and the unnamed science. Acc. Chem. Res. 1993; 26: 147–153
   Web of Science ®Google Scholar
• Hansch C., Klein T. Molecular graphics and QSAR in the study of enzyme-ligand interactions; on the definition of bioreceptors. Acc. Chem. Res. 1986; 19: 392–400
   Web of Science ®Google Scholar
• Hansch C., Leo A. Substitution Constants for Correlation Analysis in Chemistry and Biology. John Wiley & Sons, New York 1979
   Google Scholar
• Hansen C. M. The three dimensional solubility parameter — key to paint component affinities. I. Solvents, plasticizers, polymers and resins. J. Paint Technol. 1967a; 39: 104–117
   Google Scholar
• Hansen C. M. The three dimensional solubility parameter - key to paint component affinities. II. Dyes, emulsifiers, mutual solubility and compatibility, and pigments. J. Paint Technol. 1967b; 39: 509–510
   Google Scholar
• Hansen C. M., Skaarup K. The three dimensional solubility parameter — key to paint component affinities. III. Independent calculation of the parameter components. J. Paint Technol. 1967; 39: 511–514
   Google Scholar
• Harbron S., Smith B. W., Lilly M. D. Two-liquid phase biocatalysis: epoxidation of 1′7-octadiene by. Pseudomonas putida. Enzyme Microb. Technol. 1986; 8: 85–88
   Web of Science ®Google Scholar
• Harris C. M., Kell D. B. The estimation of microbial biomass. Biosensors 1985; 1: 17–84
   PubMedGoogle Scholar
• Harris C. M., Todd R. W., Bungard S. J., Lovitt R. W., Morris J. G., Kell D. B. The dielectric permittivity of microbial suspensions at radio frequencies: a novel method for the real-time estimation of microbial biomass. Enzyme Microb. Technol. 1987; 9: 181–186
   Web of Science ®Google Scholar
• Harrop A. J., Hocknull M. D., Lilly M. D. Biotransformations in organic-solvents - a difference between Gram-positive and Gram-negative bacteria. Biotechnol. Lett. 1989; 11: 807–810
   Web of Science ®Google Scholar
• Harrop A. J., Woodley J. M., Lilly M. D. Production of naphthalene-cis-glycol by Pseudomonas putida in the presence of organic solvents. Enzyme Microb. Technol. 1992; 14: 725–730
   Web of Science ®Google Scholar
• Heipieper H.-J., Keweloh H., Rehm H.-J. Influence of phenols on growth and membrane permeability of free and immobilized. Escherichia coli. Appl. Environ. Microbiol. 1991; 57(4)1213–1217
   PubMed Web of Science ®Google Scholar
• Heipieper H. J., Weber F. J., Sikkema J., Keweloh H., de Bont J. A. M. Mechanisms of resistance of whole cells to toxic organic solvents. Tibtech 1994; 12: 409–415
   Web of Science ®Google Scholar
• Hertzberg S., Kvittingen L., Anthonsen T., Skjåk-Bræk G. Alginate as immobilization matrix and stabilizing agent in a two-phase liquid system: application in lipase-catalysed reactions. Enzyme Microb. Technol. 1992; 14: 42–47
   PubMed Web of Science ®Google Scholar
• Hilge-Rotmann B., Rehm H.-J. Comparison of fermentation properties and specific enzyme activities of free and calcium-alginate-entrapped. Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 1990; 33: 54–58
   Web of Science ®Google Scholar
• Ho C. S., Ju L.-K., Baddour R. F. Enhancing penicillin fermentations by increased oxygen solubility through the addition of n-hexadecane. Biotechnol. Bioeng. 1990; 36: 1110–1118
   PubMed Web of Science ®Google Scholar
• Hochköppler A., Luisi P. L. Solubilization of soybean mitochondria in AOT/isooctane water-in-oil microemulsions. Biotechnol. Bioeng. 1989; 33: 1477–1481
   PubMed Web of Science ®Google Scholar
• Hochköppler A., Pfammatter N., Luisi P. L. Activity of yeast cells solubilized in a water-in-oil microemulsion. Chimia 1989; 43: 348–350
   Web of Science ®Google Scholar
• Hocknull M. D., Lilly M. D. The 1-dehydrogenation of hydrocortisone by Arthrobacter simplex in organic-aqueous two-liquid phase environments. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 393–398
   Google Scholar
• Hocknull M. D., Lilly M. D. The use of free and immobilised Arthrobacter simplex in organic solvent/aqueous two-liquid-phase reactors. Appl. Microbiol. Biotechnol. 1990; 33: 148–153
   PubMed Web of Science ®Google Scholar
• Horvath A. Molecular Design: Chemical Structure Generation from the Properties of Pure Organic Compounds. Elsevier, Amsterdam 1992
   Google Scholar
• Hugo W. B. Inhibition and Destruction of the Microbial Cell. Academic Press, London 1971
   Google Scholar
• Hugo W. B. Phenols: a review of their history and development as antimicrobial agents. Microbios 1978; 23: 83–85
   PubMedGoogle Scholar
• Hwanh J. Y., Arnold F. H. Enzyme design for nonaqueous solvents. Applied Biocatalysis., H. W. Blanch, D. S. Clark. Marcel Dekker, Basel 1991; 53–86
   Google Scholar
• Ingram L. O., Buttke T. M. Effects of ethanol on microorganisms. Adv. Microbial Physiol. 1985; 25: 253
   Web of Science ®Google Scholar
• Inoue A., Horikoshi K. Estimation of solvent-tolerance of bacteria by the solvent parameter Log P. J. Perm. Bioeng. 1991; 71: 194–196
   Google Scholar
• Isaacs N. S. Physical Organic Chemistry. Longman, London 1987
   Google Scholar
• Jackson R. W., DeMoss J. A. Effects of toluene on. Escherichia coli. J. Bacteriol 1965; 90: 1420–1425
   PubMed Web of Science ®Google Scholar
• Janes N., Hsu J. W., Rubin E., Taraschi T. F. Nature of alcohol and anæsthetic action on cooperative membrane equilibria. Biochemistry 1992; 31: 9467–9472
   PubMed Web of Science ®Google Scholar
• Janoff A. S., Miller K. W. A critical assessment of the lipid theories of general anaesthetic action. Biological Membranes., D. Chapman. Academic Press, London 1982; 417–476
   Google Scholar
• Junker B. H., Reddy J., Gbewonyo K., Greasham R. On-line and in-situ monitoring technology for cell density measurement in microbial and animal cell cultures. Bioprocess Eng. 1994; 10: 195–207
   Google Scholar
• Kaliszan R. Quantitative Structure-Chromatographic Retention Relationships. John Wiley & Sons, New York 1987
   Google Scholar
• Kamlet M. J., Doherty R. M., Abboud J.-L. M., Abraham M. H., Taft R. W. Linear solvation energy relationships. XXXVI. Molecular properties governing solubilities of organic nonelectrolytes in water. J. Pharmaceut. Sci. 1986a; 75: 338–349
   PubMed Web of Science ®Google Scholar
• Kamlet M. J., Doherty R. M., Abboud J.-L. M., Abraham M. H., Taft R. W. Solubility: a new look. Chemtech. 1986b; 16: 566–576
   Google Scholar
• Kamlet M. J., Doherty R. M., Veith G. D., Taft R. W., Abraham M. H. Solubility properties in polymers and biological media. VII. An analysis of toxicant properties that influence inhibition of bioluminescence in Photobacterium phosphoreum (the Microtox test). Environ. Sci. Terhnol. 1986c; 20: 690–695
   PubMed Web of Science ®Google Scholar
• Kamlet M. J., Doherty R. M., Famini G. R., Taft R. W. Linear solvation energy relationships. Local empirical rules — or fundamental laws of chemistry? The dialogue continues. A challenge to the chemometricians. Acta Chem. Scand. B 1987a; 41: 589–598
   Google Scholar
• Kamlet M. J., Doherty R. M., Veith G. D., Taft R. W., Abraham M. H. Solubility properties in polymers and biological media. VIII. An analysis of the factors that influence toxicities of organic nonelectrolytes to the Golden Orfe fish. (Leuciscus idus melanotus). Environ. Sci. Technol. 1987b; 21: 145–155
   Web of Science ®Google Scholar
• Kamlet M. J., Doherty R. M., Abraham M. H., Taft R. W. Solubility properties in biological media. XII. Regarding the mechanism of nonspecific toxicity or narcosis by organic nonelectrolytes. Quant. Struct. Act. Relat. 1988a; 7: 71–78
   Google Scholar
• Kamlet M. J., Doherty R. M., Carr P. W., Mackay D., Abraham M. H., Taft R. W. Linear solvation energy relationships. XLIV. Parameter estimation rules that allow accurate prediction of octanol/water partition coefficients and other solubility and toxicity properties of polychlorinated biphenyls and polycyclic aromatic hydrocarbons. Environ. Sci. Technol. 1988b; 22: 503–509
   PubMed Web of Science ®Google Scholar
• Kamlet M. J., Taft R. W. Linear solvation energy relationships. Local empirical rules — or fundamental laws of chemistry? A reply to the chemometricians. Acta Chem. Scand. B 1985; 39: 611–628
   Google Scholar
• Kang W., Shukla R., Sirkar K. K. Ethanol production in a microporous hollow-fiber-based extractive fermentor with immobilised yeast. Biotechnol. Bioeng. 1990; 36: 826–833
   PubMed Web of Science ®Google Scholar
• Kaprelyants A., Gottschal J. C., Kell D. B. Dormancy in nonsporulating bacteria. FEMS Microbiol. Rev. 1993; 104: 271–286
   Google Scholar
• Kaprelyants A. S., Kell D. B. Rapid assessment of bacterial viability and vitality using rhodamine 123 and flow cytometry. J. Appl. Bacteriol. 1992; 72: 410–422
   Google Scholar
• Kawabata N., Nakagawa K. Cortisol 1-dehydrogenation by cells of Arthrobacter simplex immobilized by capture on the surface of unwoven cloth coated with a pyridinium-type polymer. J. Ferment. Bioeng. 1991; 71: 19–23
   Google Scholar
• Kawakami K., Takashi A., Yoshida T. Silicone-immobilized biocatalysts effective for bioconver-sions in nonaqueous media. Enzyme Microb. Technol. 1992; 14: 371–374
   PubMed Web of Science ®Google Scholar
• Kell D. B. Protonmotive energy transduction: some physical principles and experimental approaches. Bacterial Energy Transduction., C. J. Anthony. Academic Press, London 1988; 429–490
   Google Scholar
• Kell D. B., Harris C. M. Dielectric spectroscopy and membrane organisation. J. Bioelectricity 1985; 4: 317–348
   Web of Science ®Google Scholar
• Kell D. B., Markx G. H., Davey C. L., Todd R. W. Real-time monitoring of cellular biomass: methods and applications. Trends Anal. Chem. 1990; 9: 190–194
   Web of Science ®Google Scholar
• Kell D. B., Ryder H. M., Kaprelyants A. S., Westerhoff H. V. Quantifying heterogeneity: flow cytometry of bacterial cultures. Antonie van Leeuwenhoek 1991; 60: 145–158
   PubMed Web of Science ®Google Scholar
• Kell D. B., Samworth C. M., Todd R. W., Bungard S. J., Morris J. G. Real-time estimation of microbial biomass during fermentations, using a dielectric probe. Studia Biophys. 1987; 119: 153–156
   Google Scholar
• Kell D. B., van Dam K., Westerhoff H. V. Control analysis of microbial growth and productivity. Symp. Soc. Gen. Microbiol. 1989; 44: 61–93
   Google Scholar
• Kell D. B., Westerhoff H. V. Catalytic facilitation and membrane bioenergetics. Organized Multienzyme Systems: Catalytic Properties., G. R. Welch. Academic Press, New York 1985; 63–139
   Google Scholar
• Kelly H. A. Jules Lemaire: the first to recognise the true nature of wound infection, and the first to use carbolic acid in medicine and surgery. JAMA 1901; 36: 1083–1088
   Google Scholar
• Kennedy M. J., Thakur M. S., Wang D. I. C., Stephanopoulos G. Techniques for the estimation of cell concentration in the presence of suspended solids. Biotechnol. Progr. 1992; 8: 375–381
   PubMed Web of Science ®Google Scholar
• Keweloh H., Heipieper H. J., Rehm H. J. Phenol tolerance of immobilized cells. Physiology of Immobilized Cells, J. A. M. de Bont, J. Visser, B. Mattiasson, J. Tramper. Elsevier, Amsterdam 1990; 545–550
   Google Scholar
• Khmelnitsky Y. L., Levashov A. V., Klyachko N. L., Martinek K. Engineering biocatalytic systems in organic media with low water-content. Enzyme Microb. Technol. 1988; 10: 710–724
   Web of Science ®Google Scholar
• Khmelnitsky Y. L., Mozhaev V. V., Belova A. B., Sergeeva M. V., Martinek K. Denaturation capacity: a new quantitative criterion for selection of organic solvents as reaction media in biocatalysis. Eur. J. Biochem. 1991; 198: 31–41
   PubMedGoogle Scholar
• Kita Y., Miller K. W. Partial molar volumes of some 1-alkanols in erythrocyte ghosts and lipid bilayers. Biochemistry 1982; 21: 2840–2847
   PubMed Web of Science ®Google Scholar
• Kollerup F., Daugulis A. J. Screening and identification of extractive fermentation solvents using a database. Can. J. Chem. Eng. 1985; 63: 919–927
   Web of Science ®Google Scholar
• Kollerup F., Daugulis A. J. Ethanol production by extractive fermentation — solvent identification and prototype development. Can. J. Chem. Eng. 1986; 64: 598–606
   Web of Science ®Google Scholar
• Kollie T. O., Poole C. F., Abraham M. H., Whiting G. S. Comparison of two free energy of solvation models for characterizing selectivity of stationary phases used in gas-liquid chromatography. Anal. Chem. Acta 1992; 259: 1–13
   Web of Science ®Google Scholar
• Laane C., Boeren S., Vos K. On optimizing organic solvents in multi-liquid-phase biocatalysis. Trends Biotechnol. 1985; 3: 251–252
   Web of Science ®Google Scholar
• Laane C., Boeren S., Vos K., Veeger C. Rules for optimization of biocatalysis in organic-solvents. Biotechnol. Bioeng. 1987b; 30: 81–87
   PubMed Web of Science ®Google Scholar
• Laane C., Boeren S., Hilhorst R., Veeger C. Optimization of biocatalysis in organic media. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987c; 65–84
   Google Scholar
• Laane C., Spruijt R., Hilhorst R. Regulation and prediction of enzyme activity in reversed micelles. Biocatalysis 1988; 1: 293–299
   Google Scholar
• Biocatalysis in Organic Media, C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987a
   Google Scholar
• Laroute V., Willemot R.-M. Effect of organic solvents on stability of two glycosidases and on glucosamylase-catalysed oligosaccharide synthesis. Enzyme Microb. Technol. 1992; 14: 528–534
   Web of Science ®Google Scholar
• Larrivee M. L., Poole C. F. Solvation parameter model for the prediction of breakthrough volumes in solid-phase extraction with particle-loaded membranes. Anal. Chem. 1994; 66: 139–146
   Web of Science ®Google Scholar
• Legoy M. D., Bello M., Pulvin S., Thomas D. Multiphase reactors a new opportunity. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 97–106
   Google Scholar
• Lennie S., Hailing P. J., Bell G. Causes of emulsion formation during solvent extraction of fermentation broths and its reduction by surfactants. Biotechnol. Bioeng. 1990; 35: 948–950
   PubMed Web of Science ®Google Scholar
• Lilly M. D. Two-liquid-phase biocatalytic reactions. J. Chem. Tech. Biotechnol. 1982; 32: 162–169
   Web of Science ®Google Scholar
• Lilly M. D., Brazier A. J., Hocknull M. D., Williams A. C., Woodley J. M. Biological conversions involving water-insoluble organic compounds. Biocatalysis in Organic Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 3–17
   Google Scholar
• Lilly M. D., Dervakos G. A., Woodley J. M. Opportunities in Biotransformations., L. G. Copping, R. E. Martin, J. A. Pickett, C. Bucke, A. W. Bunch. Elsevier, London 1990; 5–16
   Google Scholar
• Lilly M. D., Woodley J. M. Biocatalytic reactions involving water-insoluble organic compounds. Biocatalysis in Organic Syntheses., J. Tramper, H. C. van der Plas, P. Linko. Elsevier, Amsterdam 1985; 179–192
   Google Scholar
• Lister J. Antiseptic principle in the practice of surgery. Br. Med. J. 1867; 2: 246–248
   PubMedGoogle Scholar
• Long A., Ward O. P. Biotransformation of ben-zaldehyde by Saccharomyces cerevisiae: characterization of the fermentation and toxicity effects of substrates and products. Biotechnol. Bioeng. 1989; 34: 933–941
   PubMed Web of Science ®Google Scholar
• van Loosdrecht M. C. M., Lyklema J., Norde W., Schraa G., Zehnder A. J. B. The role of bacterial cell wall hydrophobicity in adhesion. Appl. Environ. Microbiol. 1987; 53: 1893–1897
   PubMed Web of Science ®Google Scholar
• Lovitt R. W., Kim B. H., Shen G. J., Zeikus J. G. Solvent production by microorganisms. Crit. Rev. Biotechnol. 1988; 7: 107–186
   Google Scholar
• Lucchini J. J., Corre J., Cremieux A. Antibacterial activity of phenolic compounds and aromatic alcohols. Res. Microbiol. 1990; 141: 499–510
   PubMed Web of Science ®Google Scholar
• Luisi P. L., Laane C. Solubilization of enzymes in apolar solvents via reverse micelles. TIBTech 1986; 4: 153–161
   Web of Science ®Google Scholar
• Luisi P. L., Giomini M., Pileni M. P., Robinson B. H. Reverse micelles as hosts for proteins and small molecules. Biochim. Biophys. Acta 1988; 947: 209–246
   PubMed Web of Science ®Google Scholar
• Mager P. P. Multivariate Chemometrics in QSAR: A Dialogue. Research Studies Press, Letchworth 1988
   Google Scholar
• Malinowski J. J., Daugulis A. J. Liquid-liquid and vapor liquid behavior of oleyl alcohol applied to extractive fermentation processing. Can. J. Chem. Eng. 1993; 71: 431–436
   Web of Science ®Google Scholar
• Martinek K., Berezin I. V., Khmelnitski Y u. L., Klyachko N. L., Levashov A. V. Biocatalysis 1987; 1: 9–15
   Google Scholar
• Markx G. H., Davey C. L., Kell D. B. The permittistat: a novel type of turbidostat. J. Gen. Microbiol. 1991; 137: 735–743
   Google Scholar
• Matsumura M., Märkl H. Application of solvent extraction to ethanol fermentation. Appl Microbiol. Biotechnol. 1984; 20: 371–377
   Web of Science ®Google Scholar
• Mattiasson B., Adlercreutz P. Tailoring the microenvironment of enzymes in water-poor systems. Trends Biotechnol. 1991; 9: 394–398
   PubMed Web of Science ®Google Scholar
• De Mattos M. J. T., Plomp P. J. A. M., Neijssel O. M., Tempest D. W. Influence of metabolic end-products on the growth efficiency of Klebsiella aerogenes in anaerobic chemostat culture. Antonie van Leeuwenhoek 1984; 50: 461–472
   PubMedGoogle Scholar
• McLee A. G., Davies S. L. Linear growth of a Torulopsis sp. on n-alkanes. Can. J. Microbiol. 1972; 18: 315–319
   PubMed Web of Science ®Google Scholar
• Mendes P., Kell D. B., Welch G. R. etabolic channelling in organized enzyme systems: experiments and models. Enzymology, K. Vivo Brindle. Mol. Cell Biol., Plenum Press, New York 1995; 11: 1–19, Adv.
   Google Scholar
• Messaoudi S., Lee K.-H., Beaulieu D., Baribeau J., Boucher F. Equilibria between multiple spectral forms of bacteriorhodopsin effect of delipidation, anaesthetics and solvents on their pH dependence. Biochim. Biophys. Acta 1992; 1140: 45–52
   Google Scholar
• Miles A. Lister's contributions to microbiology. Br. J. Surg. 1967; 54: 415–418
   Web of Science ®Google Scholar
• Miller K. W., Paton W. D. M., Smith R. A., Smith E. B. The pressure reversal of general anesthesia and the critical volume hypothesis. Mol. Pharmacol 1973; 9: 131–143
   PubMed Web of Science ®Google Scholar
• Minier M., Goma G. Ethanol production by extractive fermentation. Biotechnol. Bioeng. 1982; 24: 1565–1579
   PubMed Web of Science ®Google Scholar
• Mitchell R. J., Arrowsmith A., Ashton N. Mixed solvent systems for recovery of ethanol from dilute aqueous solution by liquid-liquid extraction. Biotechnol. Bioeng. 1987; 30: 348–351
   PubMed Web of Science ®Google Scholar
• Miyashita Y., Li Z., Sasaki S. Chemical pattern recognition and multivariate analysis for QSAR studies. Trends Anal. Chem. 1993; 12: 50–60
   Web of Science ®Google Scholar
• Mozhaev V. V., Khmelnitsky Y. L., Sergeeva M. V., Belova A. B., Klyachko N. L., Levashov A. V., Martinek K. Catalytic activity and denaturation of enzymes in water/organic cosolvent mixtures: α-chymotrypsin and laccase in mixed water/alcohol, water/glycol and water/formamide solvents. Eur. J. Biochem. 1989; 184: 597–602
   PubMedGoogle Scholar
• Munson C. L., King C. J. Factors influencing solvent selection for extraction of ethanol from aqueous solutions. Int. Eng. Chem. Process Design Dev. 1984; 23: 109–115
   Web of Science ®Google Scholar
• Naglak T. J., Hettwer D. J., Wang H. Y. Chemical permeabilization of cells for intracellular product release. Separation Processes in Biotechnology., J. A. Asenjo. Marcel Dekker, New York 1990; 177–205
   Google Scholar
• Nakamura K., Inoue K., Ushio K., Oka S., Ohno A. Stereochemical control on yeast reduction of a-keto esters. Reduction by immobilized bakers' yeast in hexane. J. Org. Chem. 1988; 53: 2589–2593
   Web of Science ®Google Scholar
• Nakamura K., Kondo S.-I., Kawai Y., Ohno A. Reduction by bakers' yeast in benzene. Tetrahedron Lett. 1991; 32: 7075–7078
   Google Scholar
• Naoshima Y., Maeda J., Munakata Y. Control of enantioselectivity of the bioreduction with immobilized bakers' yeast in a hexane solvent system. J. Chem. Soc. Perkin Trans. 1992; 1: 659–660
   Google Scholar
• Narayan V. S., Klibanov A. M. Are water-immiscibility and apolarity of the solvent relevant to enzyme efficiency?. Biotechnol. Bioeng. 1993; 41: 390–393
   PubMed Web of Science ®Google Scholar
• MacNaughtan M. D., Daugulis A. J. Importance of enzyme and solvent physical properties for the biocompatibility relationship of α-amino acid ester hydrolase. Enzyme Microb. Technol. 1993; 15: 114–119
   PubMed Web of Science ®Google Scholar
• Nikolova P., Ward O. P. Reductive biotransformation by wild type and mutant strains of Saccharomyces cerevisiae in aqueous-organic solvent biphasic systems. Biotechnol. Bioeng. 1992; 39: 870–876
   PubMed Web of Science ®Google Scholar
• Nikolova P., Ward O. P. Reductive biotransformation of benzaldehyde derivatives by baker's yeast in non-conventional media: effect of substrate hydrophobicity on the biocatalytic reaction. Biocatalysis 1994; 9: 329–341
   Web of Science ®Google Scholar
• Oda S., Ohta H. Microbial transformation on interface between hydrophilic carriers and hydrophobic organic solvents. Biosci. Biotechnol. Biochem. 1992; 56: 2041–2045
   PubMed Web of Science ®Google Scholar
• Omata T., Tanaka A., Fukui S. Bioconversions under hydrophobic conditions: effect of solvent polarity on steroid transformations by gel-entrapped Nocardia rhodocrous cells. Ferment. Technol. 1980; 58: 339–343
   Google Scholar
• Osborne S. J., Leaver J., Turner M. K., Dunnill P. Correlation of biocatalytic activity in an organic aqueous 2-liquid phase system with solvent concentration in the cell-membrane. Enzyme Microb. Technol. 1990; 12: 281–291
   PubMed Web of Science ®Google Scholar
• Osborne S. J., Leaver J., Turner M. K. Membrane concentrations of primary alcohols which inhibit progesterone 11α-hydroxylase in Rhizopus nigricans. Biocatalysis in Non-Conventional Media., J. Tramper, M. H. Vermiie, H. H. Beeftink, U. von Stockar. Elsevier, London 1992; 31–36
   Google Scholar
• Petrov V. V., Okorokov L. A. Increase in the anion and proton permeability of Saccharomyces carlsbergensis plasmalemma by rc-alcohols as a possible cause of its de-energization. Yeast 1990; 6: 311–318
   PubMed Web of Science ®Google Scholar
• Pethig R. Dielectric and Electronic Properties of Biological Materials. John Wiley & Sons, New York 1979
   Google Scholar
• Pethig R., Kell D. B. The passive electrical properties of biological systems: their significance in physiology, biophysics and biotechnology. Phys. Med. Biol. 1987; 32: 933–970
   PubMed Web of Science ®Google Scholar
• Phillips R. S., Matthews M. S., Olson E., von Tersch R. L. Structural and stereochemical studies of esterification of aromatic amino acids by a-chymotrypsin in alcohol solvents. Enzyme Microb. Technol. 1990; 12: 731–735
   Web of Science ®Google Scholar
• Structure and Reactivity in Reverse Micelles, M. P. Pileni. Elsevier, Amsterdam 1989
   Google Scholar
• Pinheiro H. M., Cabral J. M. S. Effects of solvent molecular toxicity and microenvironment composition on the 1-dehydrogenation activity of Arthrobacter simplex cells. Biotechnol. Bioeng. 1991; 37: 97–102
   PubMed Web of Science ®Google Scholar
• Pinheiro H. M., Cabral J. M. S. Screening of whole-cell immobilization procedures for the 1-dehydrogenation of steroids in organic medium. Enzyme Microb. Technol. 1992; 14: 619–624
   PubMed Web of Science ®Google Scholar
• Playne M. J., Smith B. R. Toxicity of organic extraction reagents to anaerobic bacteria. Biotechnol. Bioeng. 1983; 25: 1251–1265
   PubMed Web of Science ®Google Scholar
• Poole C. F., Kollie T. O., Poole S. K. Recent advances in solvation models for stationary phase characterization and the prediction of retention in gas chromatography. Chromatographia 1992; 34: 281–302
   Web of Science ®Google Scholar
• Poole C. F., Kollie T. O. Interpretation of the influence of temperature on the solvation properties of gas chromatographic stationary phases using Abraham's solvation parameter model. Anal. Chim. Acta 1993; 282: 1–17
   Web of Science ®Google Scholar
• Prausnitz J. M., Lichtenthaler R. N., de Azevedo Gomes E. Molecular Thermodynamics of Fluid-Phase Equilibria, 2nd ed. Prentice-Hall, Engle-wood Cliffs, NJ 1986
   Google Scholar
• Preusting H., Kingma J., Witholt B. Physiology and polyester formation of Pseudomonas oleovorans in continuous two-liquid-phase cultures. Enzyme Microb. Technol. 1991; 13: 770–780
   Web of Science ®Google Scholar
• Pringle M. J., Brown K. B., Miller K. W. Can the lipid theories of anaesthesia account for the cutoff in anaesthetic potency in homologous series of alcohols. Mol. Pharmacol. 1981; 19: 49–55
   PubMed Web of Science ®Google Scholar
• Reichardt C. Solvents and Solvent Effects in Organic Chemistry, 2nd ed. Verlag Chemie, Weinheim 1990
   Google Scholar
• Reslow M., Adlercreutz P., Mattiasson B. Organic solvents for bioorganic synthesis. I. Optimization of parameters for a chymotrypsin catalyzed process. Appl. Microbiol. Biotechnol. 1987; 26: 1–8
   Web of Science ®Google Scholar
• Rezessy-Szabó J. M., Huijberts G. N. M., de Bont J. A. M. Potential of organic solvents in cultivating micro-organisms on toxic water-insoluble compounds. Biocatalysis in Organic Medium., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 295–302
   Google Scholar
• Ribeiro M. H., Cabral J. M. S., Fonseca M. M. R. Production of L-tryptophan in a two-liquid-phase system. Biocatalysis in Organic Medium., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 323–329
   Google Scholar
• Rich P. R., Harper R. Partition coefficients of quinones and hydroquinones and their relation to biochemical reactivity. FEMS Lett. 1990; 269: 139–144
   PubMed Web of Science ®Google Scholar
• Richards C. D., Martin K., Gregory S., Keightley C. A., Hesketh T. R., Smith G. A., Warren G. B., Metcalfe J. C. Degenerate perturbations of protein structure as the mechanism of anaesthetic action. Nature 1978; 276: 775–779
   PubMed Web of Science ®Google Scholar
• Roffler S. R., Blanch H. W., Wilke C. R. In situ recovery of fermentation products. Trends Biotechnol. 1984; 2: 129–136
   Web of Science ®Google Scholar
• Rosenberg M. Ammonium sulphate enhances adherence of Escherichia coli J5 to hydrocarbon and polystyrene. FEMS Microbiol. Lett. 1984; 25: 41–45
   Web of Science ®Google Scholar
• Rosenberg M. Basic and applied aspects of microbial adhesion at the hydrocarbon: water interface. Crit. Rev. Microbiol. 1991; 18: 159–173
   PubMed Web of Science ®Google Scholar
• Rosenberg M., Doyle R. J. Microbial cell surface hydrophobicity: history, measurement, and significance. Microbial Cell Surface Hydrophobicity., R. J. Doyle, M. Rosenberg. American Society for Microbiology, Washington, D.C. 1990; 1–37
   Google Scholar
• Rosenberg M., Gutnick D., Rosenberg E. Adherence of bacteria to hydrocarbons: a simple method for measuring cell-surface hydrophobicity. FEMS Microbiol Lett. 1980; 9: 29–33
   Web of Science ®Google Scholar
• Rosenberg M., Kjelleberg S. Hydrophobic interactions: role in bacterial adhesion. Advances in Microbial Ecology, K. C. Marshall. Plenum Press, London 1986; Vol. 9: 353–393
   Google Scholar
• Rupley J. A., Gratton E., Careri G. Water and globular proteins. Trends Biochem. Sci. 1983; 8: 18–22
   Web of Science ®Google Scholar
• Salter G. J., Kell D. B. New materials and technology for cell immobilisation. Curr. Opinion Biotechnol. 1991; 2: 385–389
   PubMed Web of Science ®Google Scholar
• Salter G. J., Kell D. B. Rapid determination, using dielectric spectroscopy, of the toxicity of organic solvents to intact cells. Biocatalysis in Non-Conventional Media., J. Tramper, M. H. Vermtie, H. H. Beeftink, U. von Stockar. Elsevier, Amsterdam 1992; 291–297
   Google Scholar
• Sandorfy C. Mechanism of general anesthesia: is it all hydrophobic. Prog. Anesthesiol. 1980; 2: 353–359
   Google Scholar
• Schneider L. V. A three-dimensional solubility parameter approach to nonaqueous enzymology. Biotechnol. Bioeng. 1991; 37: 627–638
   PubMed Web of Science ®Google Scholar
• Schügerl K. Solvent Extraction in Biotechnology. Springer, Heidelberg 1994
   Google Scholar
• Schwan H. P. Electrical properties of tissue and cell suspensions. Adv. Biol. Med. Phys. 1957; 5: 147–209
   PubMedGoogle Scholar
• Seasholtz M. B., Kowalski B. The parsimony principle applied to multivariate calibration. Anal. Chim. Acta 1993; 111: 165–177
   Google Scholar
• Seeman P. The membrane action of anesthetics and tranquilizers.:. Pharmacol. Rev. 1972; 24: 583–655
   PubMed Web of Science ®Google Scholar
• Semenov A. N., Khmelnitsky Y. L., Berezin I. V., Martinek K. Water-organic solvent two-phase systems as media for biocatalytic reactions: the potential for shifting chemical equilibria towards higher yield of end products. Biocatalysis 1987; 1: 3–8
   Google Scholar
• Sharon D., Bar-Ness R., Rosenberg M. Measurement of the kinetics of bacterial adherence to hexadecane in polystyrene cuvettes. FEMS Microbiol. Lett. 1986; 36: 115–118
   Web of Science ®Google Scholar
• Shibata A., Morita K., Yamashita T., Kamaya H., Ueda I. Anesthetic-protein interaction: effects of volatile anesthetics on the secondary structure of poly(L-lysine). J. Pharm. Sci. 1991; 80: 1037–1041
   PubMed Web of Science ®Google Scholar
• Shorter J. Correlation Analysis of Organic Reactivity; with Particular Reference to Multiple Regression. Research Studies Press, Chichester 1982
   Google Scholar
• Sikkema J., Poolman B., Konings W. N., de Bont J. A. M. Effects of the membrane action of tetralin on the functional and structural properties of artificial and bacterial membranes. J. Bacteriol. 1992; 174: 2986–2992
   PubMed Web of Science ®Google Scholar
• Sikkema J., Weber J. J., Heipieper H. J., de Bont J. A. M. Cellular toxicity of lipophilic compounds: mechanisms, implications, and adaptations. Biocatalysis 1994; 10: 113–122
   Web of Science ®Google Scholar
• Silbiger E., Freeman A. Continuous 1-hydrocortisone dehydrogenation with in situ product recovery. Enzyme Microb. Technol. 1991; 13: 869–872
   PubMed Web of Science ®Google Scholar
• Sjöström M., Wold S. Linear solvation energy relationships. Local empirical rules — or fundamental laws of chemistry?. Acta Chem. Scand. 1981; 35: 537–554
   Google Scholar
• Slater S. J., Cox K. J. A., Lombardi J. V., Ho C., Kelly M. B., Rubin E., Stubbs C. D. Inhibition of protein kinase C by alcohols and anaesthetics. Nature 1993; 364: 82–84
   PubMed Web of Science ®Google Scholar
• Smidsrød O., Skjåk-Bræk G. Alginate as immobilisation matrix for cells. Trends Biotechnol. 1990; 8: 71–78
   PubMed Web of Science ®Google Scholar
• Snijder-Lambers A. M., Doddema H. J., Grande H. J., van Lelyveld P. H. Log p as a hydrophobicity index for biocatalysis; cofactor regeneration during enzymic steroid oxidation in organic solvents. Biocatalysis in Organic Media, C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 87–95
   Google Scholar
• Snyder L. R. Classification of the solvent properties of common liquids. J. Chromatogr. 1974; 92: 223–230
   Web of Science ®Google Scholar
• Snyder L. R. Classification of the solvent properties of common liquids. J. Chromatogr. Sci. 1978; 16: 223–234
   Web of Science ®Google Scholar
• Sode K., Karube I., Araki R., Mikami Y. Microbial conversion of pMonone by immobilized Aspergillus niger in the presence of an organic solvent. Biotechnol. Bioeng. 1989; 33: 1191–1195
   PubMed Web of Science ®Google Scholar
• Sonnleitner B., Locher G., Fiechter A. Biomass determination. J. Biotechnol. 1992; 25: 5–22
   PubMed Web of Science ®Google Scholar
• van Sonsbeek H. M., Beeftink H. H., Tramper J. Two-liquid-phase bioreactors. Enzyme Microb. Technol. 1993; 15: 722–729
   PubMed Web of Science ®Google Scholar
• Steinert H.-J., Vorlop D. D., Klien J. Steroid side chain cleavage with immobilised living cells in organic solvents. Biocatalysis in Organic-Media., C. Laane, J. Tramper, M. D. Lilly. Elsevier, Amsterdam 1987; 51–63
   Google Scholar
• Stevens S., Hofmeyer J.-H. S. Effects of ethanol, octanoic and decanoic acids on fermentation and the passive influx of protons through the plasma membrane of. Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 1993; 38: 656–663
   Web of Science ®Google Scholar
• Stevenson D. E., Storer A. C. Papain in organic solvents: determination of conditions suitable for biocatalysis and the effect on substrate specificity and inhibition. Biotechnol. Bioeng. 1991; 37: 519–527
   PubMed Web of Science ®Google Scholar
• Stoicheva N. G., Davey C. L., Markx G. H., Kell D. B. Dielectric spectroscopy: a rapid method for the determination of solvent biocompatibility during biotransformations. Biocatalysis 1989; 2: 245–255
   Google Scholar
• Svoboda P., Pytela O., Vecera M. Solvent effect — classification of parameters describing influence of solvents. Coll. Czech. Chem. Commun. 1983; 48: 3287–3306
   Google Scholar
• Taft R. W., Abboud J.-L. M., Kamlet M. J., Abraham M. H. Linear solvation energy relations. J. Solut. Chem. 1985a; 14: 153–186
   Web of Science ®Google Scholar
• Taft R. W., Abraham M. H., Doherty R. M., Kamlet M. J. The molecular properties governing solubilities of organic nonelectrolytes in water. Nature 1985b; 313: 384–386
   Web of Science ®Google Scholar
• Takeuchi K., Koike K., Ito S. Production of cis-unsaturated hydrocarbons by a strain of Rhodococcus in repeated batch culture with a phase-inversion, hollow-fiber system. J. Biotechnol. 1997; 14: 179–186
   Google Scholar
• Tanford C. The Hydrophobic Effect: Formation of Micelles and Biological Membranes. John Wiley & Sons, New York 1980
   Google Scholar
• Thorpe R. F., Ratledge C. Fatty acid distribution in triglycerides of yeasts grown on glucose on n-alkanes. J. Gen. Microbiol. 1972; 72: 151–163
   Google Scholar
• Biocatalysis in Non-Conventional Media., J. Tramper, M. H. Vermiie, H. H. Beeftink, U. von Stockar. Elsevier, Amsterdam 1992
   Google Scholar
• Trudell J. R. Role of membrane fluidity in anesthetic action. Drug and Anesthetic Effects on Membrane Structure and Function., R. C. Aloia, C. C. Curtain, L. M. Gordon. Wiley-Liss, New York 1991; 1–14
   Google Scholar
• Ueda I. Anesthesia: an interfacial phenomenon. Colloids Surf. 1989; 38: 37–48
   Google Scholar
• Ueda I. Interfacial effects of anesthetics on membrane fluidity. Drug and Anesthetic Effects on Membrane Structure and Function., R. C. Aloia, C. C. Curtain, L. M. Gordon. Wiley-Liss, New York 1991; 15–33
   Google Scholar
• Valivety R. H., Johnston G. A., Suckling C. J., Hailing P. J. Solvent effects on biocatalysis in organic systems: equilibrium position and rates of lipase catalyzed esterification. Biotechnol. Bioeng. 1991; 38: 1137–1143
   PubMed Web of Science ®Google Scholar
• van Uden N. Effects of ethanol on the temperature relations of viability and growth in yeast. Crit. Rev. Biotechnol. 1984; 1: 263–272
   Web of Science ®Google Scholar
• Vermüe M., Sikkema J., Verheul A., Bakker R., Tramper J. Toxicity of homologous series of organic solvents for the Gram-positive bacteria Arthrobacter, Nocardia sp. and the Gram-negative Acinetobacter, Pseudomonas sp. Biotechnol. Bioeng. 1993; 42: 747–758
   PubMed Web of Science ®Google Scholar
• Vollherbst-Schneck K., Sands J. A., Montenecourt B. S. Effect of butanol on lipid composition and fluidity of Clostridium acetobutylicum ATCC 824. Appl. Environ. Microbiol. 1984; 47: 193–194
   PubMed Web of Science ®Google Scholar
• Waks M. The Enzyme Catalytic Process, A. Cooper, J. L. Houben, L. V. Chien. Plenum Press, New York 1989
   Google Scholar
• Walter R. P., Kell D. B., Morris J. G., James R., Adams J. M. Catalytic activity of Candida cylindracea lipase immobilised on ceramic supports. Biotechnol. Lett. 1989; 3: 345–348
   Google Scholar
• Westerhoff H. V., Kell D. B., Kamp F., van Dam K. The membranes involved in proton-mediated free-energy transduction: thermodynamic implications of their physical structure. Microcompartmentation., D. P. Jones. CRC Press, Boca Raton, FL 1988; 115–154
   Google Scholar
• Wilson L., Famini G. R. Using theoretical descriptors in quantitative structure activity relationships: some toxicological indices. J. Med. Chem. 1991; 34: 1668–1674
   PubMed Web of Science ®Google Scholar
• Wold S., Sjöström M. Linear free energy relationships. Local empirical rules — or fundamental laws of chemistry? A reply to Kamlet and Taft. Acta Chem. Scand. 1986; B40: 270–277
   Google Scholar
• Woldringh C. L. Effects of toluene and phenethyl alcohol on the ultrastructure of. Escherichia coli. J. Bacteriol. 1973; 114: 1359–1361
   PubMed Web of Science ®Google Scholar
• Woodley J. M., Brazier A. J., Lilly M. D. Lewis cell studies to determine reactor design data for two-liquid-phase bacterial and enzymic reactions. Biotechnol. Bioeng. 1991a; 37: 133–140
   PubMed Web of Science ®Google Scholar
• Woodley J. M., Cunnah P. J., Lilly M. D. Stirred tank two-liquid phase biocatalytic reactor studies, kinetics, evaluation and modeling of substrate mass transfer. Biocatalysis 1991b; 5: 1–12
   Web of Science ®Google Scholar
• Woodley J. M., Lilly M. D. Process engineering of two-liquid phase biocatalysis. Biocatalysis in Non-Conventional Media., J. Tramper, M. H. Vermue, H. H. Beeftink, U. von Stockar, 1992; 147–154
   Google Scholar
• Wu J. J., Clausen E. C., Gaddy J. L. A comparison of the effects of acetophenone, 1-hexanol, and hexane on S. cerevisiae, Z. mobilis in batch and continuous immobilized-cell culture. Appl. Biochem. Biotechnol. 1991; 28/29: 797–808
   Web of Science ®Google Scholar
• Yalkowsky S. H., Valvani S. C., Amidon G. L. Solubility of nonelectrolytes in polar solvents. IV. Nonpolar drugs in mixed solvents. J. Pharmaceut. Sci. 1976; 65: 1488–1494
   PubMed Web of Science ®Google Scholar
• Zaks A. Enzymes in organic solvents. Biocatalysts for Industry., J. S. Dordick. Plenum Press, London 1991; 161–180
   Google Scholar
• Zaks A. Protein-water interactions: role in protein structure and stability. Stability of Protein Pharmaceuticals, Part A: Chemical and Physical Pathways of Protein Degradation., T. J. Ahern, M. C. Manning. Plenum Press, New York 1992; 249–271
   Google Scholar
• Zaks A., Klibanov A. M. Enzyme-catalyzed processes in organic solvents. Proc. Natl. Acad. Sci. U.S.A. 1985; 82: 3192–3196
   PubMed Web of Science ®Google Scholar
• Zaks A., Klibanov A. M. Enzymatic catalysis in nonaqueous solvents. J. Biol. Chem. 1988; 263: 3194–3201
   PubMed Web of Science ®Google Scholar
• Zaks A., Russell A. J. Enzymes in organic-solvents: properties and applications. J. Biotechnol. 1988; 8: 259–270
   Web of Science ®Google Scholar