Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 8, 1991 - Issue 1
46
Views
24
CrossRef citations to date
0
Altmetric
Original Article

Chronopharmacokinetics of Valproic Acid Following Constant-Rate Administration in Mice

, &
Pages 35-43 | Received 01 Aug 1990, Published online: 07 Jul 2009

References

  • Reinberg A, Smolensky M H. Orcadian changes of drug disposition in man. Clin Pharmacokinet 1982; 7: 401–20
  • Haus E, Halberg F, Kuhl J FW, Lakatua D J. Chronopharmacology in animals. Chronobiotogical aspects of endocrinology, J Aschoff, F Ceresa, F Halberg. Schattauer, Stuttgart 1974; 269–304
  • Bélanger P M, Labrecque G, Doré F. Rate-limiting steps in the temporal variations of the pharmacokinetics of some selected drugs. Chronobiology 1982–1983, E Haus, S Kabat. Karger, Basel 1984; 356–63
  • Nakano S, Watanabe H, Nagai K, Ogawa N. Circadian stage dependent changes in diazepam kinetics. Clin Pharmacol Ther 1984; 36: 271–7
  • Miller M A, Parker J M, Colás A E. Circadian rhythm of rat hepatic cytochrome P-450 reductase. Life Sci 1978; 23: 217–22
  • Gurr J A, Elvehjem R S, Potter V R. Diurnal variations in inducibility of rat liver tyrosine aminotransferase activity. Life Sci 1978; 23: 1301–8
  • Beckett A H, Rowland M. Rhythmic urinary excretion of amphetamine in man. Nature (Lond) 1964; 204: 1203–4
  • Reinberg A, Zagula-Mally Z, Ghata J, Halberg F. Circadian rhythm in duration of salicylate excretion referred to phase of excretory rhythm and routine. Proc Soc Exp Biol Med 1967; 124: 826–32
  • Labrecque G, Bélanger P M, Dore F, Lalande M. 24-hour variations in the distribution of labeled microspheres to the intestine, liver and kidneys. Annu Rev Chronopharmacol 1988; 5: 445–8
  • Reinberg A, Gervais P, Chaussade M, Fraboulet C, Duburque B. Circadian changes in effectiveness of corticosteroids in 8 patients with allergic asthma. J Allergy Clin Immunol 1983; 71: 425–33
  • Hrushesky W JM. Circadian timing of cancer chemotherapy. Science 1985; 228: 73–5
  • Ohdo S, Nakano S, Ogawa N. Chronopharmacological study of sodium valproate in mice: dose-concentration-response relationship. Jpn J Pharmacol 1988; 47: 11–9
  • Ohdo S, Nakano S, Ogawa N. Chronotoxicity of sodium valproate and its mechanisms in mice: dose-concentration-response relationship. Chronobiol Int 1989; 6: 229–35
  • Shargel L, Yu A BC. Intravenous infusion. Applied biopharmaceutics and pharmacokinetics, 2nd edition, L Shargel, A BC Yu. Appleton-Century-Crofts, East Norwalk 1985; 213–27
  • Nau H, Zierer R, Spielmann H, Neubert D, Gansau Ch. A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations. Life Sci 1981; 29: 2803–14
  • Benet L Z, Sheiner L B. Pharmacokinetics: the dynamics of drug absorption, distribution, and elimination. Goodman and Oilman's the pharmacological basis of therapeutics, 7th edition, A G Gilman, L S Goodman, T W Rail, F Murad. Macmillan, New York 1985; 3–34
  • Kohda Y, Nishihara K, Saitoh Y, Nakagawa F, Tamura Z. Clinical evaluation of homogeneous enzyme immunoassay technique for determination of valproic acid in plasma. J Clin Exp Med 1980; 115: 813–5, (in Japanese)
  • Alzet osmotic pump technical information manual. Alza Corp, Palo Alto 1989
  • Abrams R, Hammel H T. Hypothalamic temperature in unanesthetized albino rats during feeding and sleeping. Am J Physiol 1964; 206: 641–6
  • Halberg F, Halberg E. Chronopharmacology and further steps toward chronotherapy. Pharmacokinetic basis for drug treatment, L Z Benet, N Massoud, J G Gambertoglio. Raven Press, New York 1984; 221–48
  • Gugler R, Von Unruh G E. Clinical pharmacokinetics of valproic acid. Clin Pharmacokinel 1980; 5: 67–83
  • Scheving L E, Pauly S E, Hutsai T. Circadian fluctuation in plasma proteins of the rat. Am J Physiol 1968; 215: 1096–101
  • Vachon C, Savoie L. Circadian variation of food intake and digestive tract contents in the rat. Physiol Behav 1987; 39: 629–32
  • Armstrong S, Clarke J, Coleman G. Light-dark variation in laboratory rat stomach and small intestine content. Physiol Behav 1978; 21: 785–8
  • Bourdel G, Kande J, Robin D, Robin P. Quantitative and qualitative circadian variations of amino acid intestinal efflux in mixed-fed and in protein-meal-fed rats. J Nutr 1981; 111: 1528–35
  • Dickinson R G, Harland R C, Rodgers R M, Gordon W P, Lynn R K, Gerber N. Dose dependent metabolism and enterohepatic recirculation of valproic acid in the rat. Proc West Pharmacol Soc 1978; 21: 217–20
  • Tulloch I F, Walter D S, Howe G M, Howe S J. The relationship between plasma concentration of valproic acid and its anticonvulsant and behavioural effects in the rat. Neuropharmacology 1982; 21: 555–62

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.