Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 9, 1992 - Issue 4
10
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Behavioral and Morphological Studies of Fetal Neural Transplants into SCN-Lesioned Rats

, &
Pages 278-296 | Received 01 Jun 1991, Accepted 05 Aug 1991, Published online: 07 Jul 2009

References

  • Moore RY, Eichler VB. Loss of circadian corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 1972; 42: 201–6
  • Stephan FK, Zucker I. Circadian rhythms in drinking behavior and locomotor activity are eliminated by suprachiasmatic lesions. Proc Natl Acad Sci USA 1972; 54: 1521–7
  • Moore RY. Organization and function of a central nervous system circadian oscillator: the suprachiasmatic hypothalamic nucleus. Fed Proc 1983; 42: 2783–9
  • Van den Pol AN. The hypothalamic suprachiasmatic nucleus of rat: intrinsic anatomy. JComp Neurol 1980; 191: 661–702
  • Card JP, Moore RY. The suprachiasmatic nucleus of the golden hamster: immunohistochemical analysis of cell and fiber distribution. Neuroscience 1984; 13: 415–31
  • Watts AG, Swanson LW, Sanchez-Watts G. The efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of phaseolus vulgaris leucoaaglutinin (PHA-L) in the rat. J Comp Neurol 1987; 258: 204–29
  • Russak B, Gross G. Suprachiasmatic stimulation phase shifts rodent circadian rhythm. Science 1982; 215: 1407–9
  • Inouye S JT, Kawamura H. Persistence of circadian rhythmicity in a mammalian hypothalamic “island” containing the suprachiasmatic nucleus. Proc Natl Acad Sci USA 1979; 76: 5962–6
  • Inouye S TJ, Kawamura H. Characteristics of a circadian pacemaker in the suprachiasmatic nucleus. J Comp Physiol [B] 1982; 146: 153–60
  • Shibata S, Oomura Y, Kita H, Hattore K. Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice. Brain Res 1982; 247: 154–8
  • Green DJ, Gillete R. Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice. Brain Res 1982; 245: 198–200
  • Newman GC, Hospod FE. Rhythm of suprachiasmatic nucleus 2-deoxyglucose uptake in vitro. Brain Res 1986; 381: 345–50
  • Earnest DJ, Sladek CD. Circadian rhythms of vasopressin release from individual rat suprachiasmatic explants in vitro. Brain Res 1986; 382: 129–33
  • Drucker-Colin R, Aguilar-Roblero R, Garcia-Hernandez F, Fernandez-Cancino F, Bermudez-Rattoni F. Fetal suprachiasmatic nucleus transplants: diurnal rhythm recovery of lesioned rats. Brain Res 1984; 311: 353–7
  • Sawaki Y, Nihonmatsu I, Kawamura H. Transplantation of the neonatal suprachiasmatic nuclei into rats with complete bilateral suprachiasmatic lesions. Neurosci Res 1984; 1: 67–72
  • Aguilar-Roblero R, Garcia-Hernandez F, Aguilar R, Arankowsky-Sandoval G, Drucker-Colin R. Suprachiasmatic nucleus transplants functions as endogenous oscillator only in constant darkness. Neurosci Lett 1986; 69: 47–52
  • Lehman MN, Silver R, Gladstone WR, Kahn RM, Gibson M, Bitman EL. Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain. J Neurosci 1987; 7: 1626–38
  • DeCoursey PJ, Buggy J. Circadian rhythmicity after neural transplant to hamster third ventricle: specificity of suprachiasmatic nuclei. Brain Res 1989; 500: 263–75
  • Ralph MR, Foster RG, Davis F, Menaker M. Transplanted suprachiasmatic nucleus determines circadian period. Science 1990; 247: 975–8
  • Garcia-Hernandez F, Aguilar-Roblero R, Drucker-Colin R. Transplantation of the fetal occipital cortex to the third ventricle of SCN-lesioned rats induces a diurnal rhythm in drinking behavior. Brain Res 1987; 418: 193–7
  • Mesulam MM. Tetramethyl benzidine for horseradish peroxidase neurochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. J. Histochem Cytochem 1978; 26: 106–17
  • Hsu SM, Raine L, Fanger H. The use of avidin-biotin-peroxidase complex (ABC) in immunoperoxi-dase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29: 577–89
  • Harrington ME, DeCoursey PJ, Buggy J. Circadian pacemaker (SCN) transplants into lateral ventricles fail to restore locomotor rhythmicity in arrhythmic hamsters. Soc Neurosci Abstracts 1987; 13: 213
  • Aguilar-Roblero R, Morin LP, Moore RY. Is the fetal SCN sufficient to induce rhythm recovery when transplanted to the SCN-lesioned hamsters?. Soc Neurosci Abstracts 1988; 14: 49
  • Honma K, Hiroshige T. Endogenous ultradian rhythms in rats exposed to prolonged continuous light. Am J Physiol 1978; 235: R250–6
  • Schwartz WJ, Davidsen LC, Smith CB. In vivo metabolic activity of a putative circadian oscillator, the rat suprachiasmatic nucleus. J Comp Neurol 1980; 189: 157–67
  • Shibata S, Oomura Y, Liou SY, Veki S. Electrophysiological studies on the development of suprachiasmatic neuronal activity in hypothalamic slice preparation. Dev Brain Res 1984; 13: 29–35
  • Halberg F. Physiologic 24-hrs periodicity in human beings and mice, the lighting regimen and daily routine. Photoperiodism and related phenomena in plants and animals, RB Withrow. AAAS, Washington 1959; 803–78
  • DeCoursey PJ. Phase control of activity in a rodent. Cold Spring Harbor Symp Quant Biol 1960; 25: 49–54
  • Roberts MH, Bernstein MF, Moore RY. Differentiation of the suprachiasmatic nucleus in fetal rat anterior hypothalamic transplants in oculo. Dev Brain Res 1987; 32: 59–66
  • Wiegand SJ, Gash DM. Organization and efferent connections of transplanted suprachiasmatic nuclei. J Comp Neurol 1988; 267: 562–79
  • Altman J, Bayer SA. Development of the diencephalon in the rat I. Autoradiographic study of the time of origin and settling patterns of neurons of the hypothalamus. J Comp Neurol 1978; 182: 945–71
  • Bernstein JJ, Connor JR. Somatostatin-like neurons are expressed in fetal neocortical homografts in adult rats spinal cord. Brain Res 1986; 374: 147–52
  • Connor JR, Bernstein JJ. Vasoactive intestinal polypeptide neurons in fetal cortical homografts to adult rat spinal cord. Brain Res 1986; 367: 214–21
  • Jaeger CB, Lund RD. Transplantation of embryonic occipital cortex to the brain of newborn rats: an autoradiographic study of transplanted histogenesis. Exp Brain Res 1980; 40: 265–72
  • Das GD, Ross DT. Neural transplantation: autoradiographic analysis of histogenesis in neocortical transplants. Int J Dev Neurosci 1986; 4: 69–79
  • Moore RY, Klein DC. Visual pathways and the central neural control of a circadian rhythm in the pineal N-acetyl transferase activity. Brain Res 1974; 71: 17–33
  • Shibata S, Aguilar-Roblero R, Moore RY. Los transplantes del nucleo supraquiasmatico presentan ritmos circadicos de actividad electrica y metabolica. Resumenes del congreso de la Sociedad Mexi-cana de Ciencias Fisiologicas. 1988; 31, C-160
  • Aguilar-Roblero R, Shibata S, Speh JC, Drucker-Colín R, Moore RY. Morphological and functional development of the suprachiasmatic nucleus in transplanted fetal hypothalamus. Brain Res 1992, (in press)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.