Complement activation in Puumala hantavirus infection correlates with disease severity

References

• Vaheri A, Mills JN, Spiropoulou CF, Hjelle B. Hantaviruses. Palmer SR, Lord Soulsby, Torgerson PR, Brown DWG, Oxford Textbook of Zoonoses—Biology, Clinical Practice and Public Health Control. 2nd Oxford: Oxford University Press; 2011:307–322.
   Google Scholar
• Makary P, Kanerva M, Ollgren J, Virtanen MJ, Vapalahti O, Lyytikainen O. Disease burden of Puumala virus infections, 1995–2008. Epidemiol Infect. 2010: 138:1484–92.
   PubMed Web of Science ®Google Scholar
• Vapalahti O, Mustonen J, Lundkvist A, Henttonen H, Plyusnin A, Vaheri A. Hantavirus infections in Europe. Lancet Infect Dis. 2003;310:653–61.
   Google Scholar
• Mustonen J, Partanen J, Kanerva M, Pietila K, Vapalahti O, Pasternack A, . Genetic susceptibility to severe course of nephropathia epidemica caused by Puumala hantavirus. Kidney Int. 1996;49:217–21.
   PubMed Web of Science ®Google Scholar
• Kanerva M, Paakkala A, Mustonen J, Paakkala T, Lahtela J, Pasternack A. Pulmonary involvement in nephropathia epidemica: radiological findings and their clinical correlations. Clin Nephrol. 1996;46:369–78.
   PubMed Web of Science ®Google Scholar
• Paakkala A, Makela S, Hurme M, Partanen J, Huhtala H, Mustonen J. Association of chest radiography findings with host-related genetic factors in patients with nephropathia epidemica. Scand J Infect Dis. 2008;40:254–8.
   PubMed Web of Science ®Google Scholar
• Paakkala A, Mustonen J. Radiological findings and their clinical correlations in nephropathia epidemica. Acta Radiol. 2007; 48:345–50.
   PubMed Web of Science ®Google Scholar
• Clement J, Colson P, McKenna P. Hantavirus pulmonary syndrome in New England and Europe. N Engl J Med. 1994;331:545–6; author reply 547–8.
   PubMed Web of Science ®Google Scholar
• Makela S, Kokkonen L, Ala-Houhala I, Groundstroem K, Harmoinen A, Huhtala H, . More than half of the patients with acute Puumala hantavirus infection have abnormal cardiac findings. Scand J Infect Dis. 2009;41:57–62.
   PubMed Web of Science ®Google Scholar
• Zaki SR, Greer PW, Coffield LM, Goldsmith CS, Nolte KB, Foucar K, . Hantavirus pulmonary syndrome. Pathogenesis of an emerging infectious disease. Am J Pathol. 1995; 146:552–79.
   PubMed Web of Science ®Google Scholar
• Kanerva M, Mustonen J, Vaheri A. Pathogenesis of puumala and other hantavirus infections. Rev Med Virol. 1998; 82:67–86.
   Google Scholar
• Paakkala A, Mustonen J, Viander M, Huhtala H, Pasternack A. Complement activation in nephropathia epidemica caused by Puumala hantavirus. Clin Nephrol. 2000; 536:424–31.
   Google Scholar
• Walport MJ. Complement. First of two parts. N Engl J Med. 2001;344:1058–66.
   PubMed Web of Science ®Google Scholar
• Podack ER, Muller-Eberhard HJ. Isolation of human S-protein, an inhibitor of the membrane attack complex of complement. J Biol Chem. 1979;254:9808–14.
   PubMed Web of Science ®Google Scholar
• Vapalahti O, Lundkvist A, Kallio-Kokko H, Paukku K, Julkunen I, Lankinen H, . Antigenic properties and diagnostic potential of puumala virus nucleocapsid protein expressed in insect cells. J Clin Microbiol. 1996;341:119–25.
   Google Scholar
• Temonen M, Vapalahti O, Holthofer H, Brummer-Korvenkontio M, Vaheri A, Lankinen H. Susceptibility of human cells to Puumala virus infection. J Gen Virol. 1993; 74(Pt 3):515–8.
   PubMedGoogle Scholar
• Terajima M, Hayasaka D, Maeda K, Ennis FA. Immunopathogenesis of hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome: Do CD8+ T cells trigger capillary leakage in viral hemorrhagic fevers? Immunol Lett. 2007;113:117–20.
   PubMed Web of Science ®Google Scholar
• Linderholm M, Ahlm C, Settergren B, Waage A, Tarnvik A. Elevated plasma levels of tumor necrosis factor (TNF)-alpha, soluble TNF receptors, interleukin (IL)-6, and IL-10 in patients with hemorrhagic fever with renal syndrome. J Infect Dis. 1996;173:38–43.
   PubMed Web of Science ®Google Scholar
• Tsukada H, Ying X, Fu C, Ishikawa S, McKeown-Longo P, Albelda S, . Ligation of endothelial alpha v beta 3 integrin increases capillary hydraulic conductivity of rat lung. Circ Res. 1995;77:651–9.
   PubMed Web of Science ®Google Scholar
• Ishikawa S, Tsukada H, Bhattacharya J. Soluble complex of complement increases hydraulic conductivity in single microvessels of rat lung. J Clin Invest. 1993;91:103–9.
   PubMed Web of Science ®Google Scholar
• Bossi F, Fischetti F, Pellis V, Bulla R, Ferrero E, Mollnes TE, . Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex. J Immunol. 2004; 173:6921–7.
   PubMed Web of Science ®Google Scholar
• Langlois PF, Gawryl MS. Accentuated formation of the terminal C5b-9 complement complex in patient plasma precedes development of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138:368–75.
   PubMed Web of Science ®Google Scholar
• Colins JD, Burwell D, Furmanski S, Lorber P, Steckel RJ. Minimal detectable pleural effusions. A roentgen pathology model. Radiology. 1972;105:51–3.
   PubMed Web of Science ®Google Scholar
• Basu A, Chaturvedi UC. Vascular endothelium: the battlefield of dengue viruses. FEMS Immunol Med Microbiol. 2008;53:287–99.
   PubMedGoogle Scholar
• Avirutnan P, Punyadee N, Noisakran S, Komoltri C, Thiemmeca S, Auethavornanan K, . Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J Infect Dis. 2006;193:1078–88.
   PubMed Web of Science ®Google Scholar
• Nascimento EJ, Silva AM, Cordeiro MT, Brito CA, Gil LH, Braga-Neto U, . Alternative complement pathway deregulation is correlated with dengue severity. PLoS One. 2009; 48:e6782.
   Google Scholar
• Monsalvo AC, Batalle JP, Lopez MF, Krause JC, Klemenc J, Hernandez JZ, . Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med. 2011;17:195–9.
   PubMed Web of Science ®Google Scholar
• Makela S, Mustonen J, Ala-Houhala I, Hurme M, Koivisto AM, Vaheri A, . Urinary excretion of interleukin-6 correlates with proteinuria in acute Puumala hantavirus-induced nephritis. Am J Kidney Dis. 2004;43:809–16.
   PubMed Web of Science ®Google Scholar
• Katz Y, Revel M, Strunk RC. Interleukin 6 stimulates synthesis of complement proteins factor B and C3 in human skin fibroblasts. Eur J Immunol. 1989;19:983–8.
   PubMed Web of Science ®Google Scholar
• Morgan BP. Regulation of the complement membrane attack pathway. Crit Rev Immunol. 1999;19:173–98.
   PubMed Web of Science ®Google Scholar
• Weigelt JA, Chenoweth DE, Borman KR, Norcross JF. Complement and the severity of pulmonary failure. J Trauma. 1988;28:1013–9.
   PubMedGoogle Scholar
• Blanchong CA, Zhou B, Rupert KL, Chung EK, Jones KN, Sotos JF, . Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease. J Exp Med. 2000;191: 2183–96.
   PubMed Web of Science ®Google Scholar