Vitamin D status is associated with bone mineral density and functional exercise capacity in patients with chronic obstructive pulmonary disease

References

• Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, . Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176:532–55.
   PubMed Web of Science ®Google Scholar
• Barnes PJ, Celli BR. Systemic manifestations and comorbidities of COPD. Eur Respir J. 2009;33:1165–85.
   PubMed Web of Science ®Google Scholar
• Graat-Verboom L, Wouters EF, Smeenk FW, van den Borne BE, Lunde R, Spruit MA. Current status of research on osteoporosis in COPD: a systematic review. Eur Respir J. 2009;34:209–18.
   PubMed Web of Science ®Google Scholar
• Seymour JM, Spruit MA, Hopkinson NS, Natanek SA, Man WD, Jackson A, . The prevalence of quadriceps weakness in COPD and the relationship with disease severity. Eur Respir J. 2010;36:81–8.
   PubMed Web of Science ®Google Scholar
• Bossenbroek L, de Greef MH, Wempe JB, Krijnen WP, Ten Hacken NH. Daily physical activity in patients with chronic obstructive pulmonary disease: a systematic review. COPD. 2011;8:306–19.
   PubMedGoogle Scholar
• WHO Scientific Group on the Prevention and Management of Osteoporosis. Prevention and management of osteoporosis; report of a WHO scientific group. 2003. http://whqlibdoc.who.int/trs/WHO_TRS_921.pdf
   Google Scholar
• Lehouck A, Boonen S, Decramer M, Janssens W. COPD, bone metabolism, and osteoporosis. Chest. 2011;139:648–57.
   PubMed Web of Science ®Google Scholar
• Vieth R. The role of vitamin D in the prevention of osteoporosis. Ann Med. 2005;37:278–85.
   PubMed Web of Science ®Google Scholar
• Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ. 2003;326:469.
   PubMed Web of Science ®Google Scholar
• Schols AM, Broekhuizen R, Weling-Scheepers CA, Wouters EF. Body composition and mortality in chronic obstructive pulmonary disease. Am J Clin Nutr. 2005;82:53–9.
   PubMed Web of Science ®Google Scholar
• Rabinovich RA, Vilaro J. Structural and functional changes of peripheral muscles in chronic obstructive pulmonary disease patients. Curr Opin Pulm Med. 2010;16:123–33.
   PubMed Web of Science ®Google Scholar
• Dirks-Naylor AJ, Lennon-Edwards S. The effects of vitamin D on skeletal muscle function and cellular signaling. J Steroid Biochem Mol Biol. 2011;125:159–68.
   PubMed Web of Science ®Google Scholar
• Costa EM, Blau HM, Feldman D. 1,25-dihydroxyvitamin D3 receptors and hormonal responses in cloned human skeletal muscle cells. Endocrinology. 1986;119:2214–20.
   PubMed Web of Science ®Google Scholar
• Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, . Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ. 2009;339:b3692.
   PubMed Web of Science ®Google Scholar
• Janssens W, Lehouck A, Carremans C, Bouillon R, Mathieu C, Decramer M. Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med. 2009;179:630–6.
   PubMed Web of Science ®Google Scholar
• Janssens W, Bouillon R, Claes B, Carremans C, Lehouck A, Buysschaert I, . Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax. 2010;65: 215–20.
   PubMed Web of Science ®Google Scholar
• Forli L, Halse J, Haug E, Bjortuft O, Vatn M, Kofstad J, . Vitamin D deficiency, bone mineral density and weight in patients with advanced pulmonary disease. J Intern Med. 2004;256:56–62.
   PubMed Web of Science ®Google Scholar
• Forli L, Bjortuft O, Boe J. Vitamin D status in relation to nutritional depletion and muscle function in patients with advanced pulmonary disease. Exp Lung Res. 2009;35:524–38.
   PubMed Web of Science ®Google Scholar
• Hopkinson NS, Li KW, Kehoe A, Humphries SE, Roughton M, Moxham J, . Vitamin D receptor genotypes influence quadriceps strength in chronic obstructive pulmonary disease. Am J Clin Nutr. 2008;87:385–90.
   PubMed Web of Science ®Google Scholar
• Kuchuk NO, Pluijm SM, van Schoor NM, Looman CW, Smit JH, Lips P. Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons. J Clin Endocrinol Metab. 2009;94:1244–50.
   PubMed Web of Science ®Google Scholar
• Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266–81.
   PubMed Web of Science ®Google Scholar
• Franco CB, Paz-Filho G, Gomes PE, Nascimento VB, Kulak CA, Boguszewski CL, . Chronic obstructive pulmonary disease is associated with osteoporosis and low levels of vitamin D. Osteoporos Int. 2009;20:1881–7.
   PubMed Web of Science ®Google Scholar
• Graat-Verboom L, Spruit MA, van den Borne BE, Smeenk FW, Martens EJ, Lunde R, . Correlates of osteoporosis in chronic obstructive pulmonary disease: an underestimated systemic component. Respir Med. 2009;103:1143–51.
   PubMed Web of Science ®Google Scholar
• Spruit MA, Watkins ML, Edwards LD, Vestbo J, Calverley PM, Pinto-Plata V, . Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort. Respir Med. 2010;104:849–57.
   PubMed Web of Science ®Google Scholar
• van Dam RM, Snijder MB, Dekker JM, Stehouwer CD, Bouter LM, Heine RJ, . Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study. Am J Clin Nutr. 2007;85:755–61.
   PubMed Web of Science ®Google Scholar
• Black PN, Scragg R. Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination survey. Chest. 2005;128:3792–8.
   PubMed Web of Science ®Google Scholar
• Zosky GR, Berry LJ, Elliot JG, James AL, Gorman S, Hart PH. Vitamin D deficiency causes deficits in lung function and alters lung structure. Am J Respir Crit Care Med. 2011;183:1336–43.
   PubMed Web of Science ®Google Scholar
• Herr C, Greulich T, Koczulla RA, Meyer S, Zakharkina T, Branscheidt M, . The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer. Respir Res. 2011;12:31.
   PubMed Web of Science ®Google Scholar
• Graat-Verboom L, van den Borne BE, Smeenk FW, Spruit MA, Wouters EF. Osteoporosis in COPD outpatients based on bone mineral density and vertebral fractures. J Bone Miner Res. 2011;26:561–8.
   PubMed Web of Science ®Google Scholar
• Ringbaek T, Martinez G, Durakovic A, Thogersen J, Midjord AK, Jensen JE, . Vitamin D status in patients with chronic obstructive pulmonary disease who participate in pulmonary rehabilitation. J Cardiopulm Rehabil Prev. 2011;31:261–7.
   PubMed Web of Science ®Google Scholar
• Marantes I, Achenbach SJ, Atkinson EJ, Khosla S, Melton LJ, III, Amin S. Is vitamin D a determinant of muscle mass and strength? J Bone Miner Res. 2011.
   PubMed Web of Science ®Google Scholar
• Ceglia L, Chiu GR, Harris SS, Araujo AB. Serum 25-hydroxyvitamin D concentration and physical function in adult men. Clin Endocrinol (Oxf). 2011;74:370–6.
   PubMed Web of Science ®Google Scholar
• Houston DK, Cesari M, Ferrucci L, Cherubini A, Maggio D, Bartali B, . Association between vitamin D status and physical performance: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2007;62:440–6.
   PubMed Web of Science ®Google Scholar
• Gerdhem P, Ringsberg KA, Obrant KJ, Akesson K. Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporos Int. 2005;16:1425–31.
   PubMed Web of Science ®Google Scholar
• Stockton KA, Mengersen K, Paratz JD, Kandiah D, Bennell KL. Effect of vitamin D supplementation on muscle strength: a systematic review and meta-analysis. Osteoporos Int. 2011;22:859–71.
   PubMed Web of Science ®Google Scholar