Nitric Oxide: Biological Mediator, Modulator and Effector

References

• Hooper A B. Ammonia oxidation and energy transduction in the nitrifying bacteria. Microbial Chemoautotrophy, W R Strogl, O H Tuovinen. Ohio State University Press, Columbus 1984; 133–67
   Google Scholar
• Mitchell H H, Schonle H A, Grindly H S. The origin of the nitrates in the urine. J Biol Chem 1916; 24: 461–90
   Google Scholar
• Green L C, de Luzuriaga K R, Wagner D A, et al. Nitrate biosynthesis in man. Proc Natl Acad Sci USA 1981; 78: 7764–8
   PubMed Web of Science ®Google Scholar
• Stuehr D J, Marietta M A. Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 1985; 82: 7738–42
   PubMed Web of Science ®Google Scholar
• Hibbs J B, Jr, Taintor R R, Vavrin Z. Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. Science 1987; 235: 473–6
   PubMed Web of Science ®Google Scholar
• Furchgott R F, Zawadzki J V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373–6
   PubMed Web of Science ®Google Scholar
• Furchgott R F. Studies on relaxation of rabbit aorta by sodium nitrite: the basis for the proposal that the acid-activatable inhibitory factor from bovine retractor penis is inorganic nitrite and that endothelium-derived relaxing factor is nitric oxide. Vasodilatation: Vascular Smooth Muscle, Peptides, Autonomic Nerves, and Endothelium, P M Vanhoutte. Raven Press, New York 1988; 401–14
   Google Scholar
• Ignarro L J, Buga G M, Wood K S, Byrns R E, Chaudhri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987; 84: 9625–9
   Google Scholar
• Palmer R MJ, Ferrige A G, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524–6
   PubMed Web of Science ®Google Scholar
• Palmer R MJ, Ashton D S, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333: 664–6
   PubMed Web of Science ®Google Scholar
• Radomski M W, Palmer R MJ, Moncada S. The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochem Biophys Res Commun 1987; 148: 1482–9
   PubMed Web of Science ®Google Scholar
• Radomski M W, Palmer R MJ, Moncada S. Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets. Br J Pharmacol 1987; 92: 181–7
   PubMed Web of Science ®Google Scholar
• Radomski M W, Palmer R MJ, Moncada S. An L-arginine: nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 1990; 87: 5193–7
   PubMed Web of Science ®Google Scholar
• Myers P R, Minor R L, Jr, Guerra R, Jr, Bates J N, Harrison D G. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitroso-cysteine than nitric oxide. Nature 1990; 345: 161–3
   PubMed Web of Science ®Google Scholar
• Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6: 3051–64
   PubMed Web of Science ®Google Scholar
• Pufahl R A, Marietta M A. Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis. Biochem Biophys Res Commun 1993; 193: 963–70
   Google Scholar
• Bredt D S, Hwang P H, Glatt C, et al. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 1991; 351: 714–8
   PubMed Web of Science ®Google Scholar
• Marsden P A, Schappert K T, Chen H S, et al. Molecular cloning and characterization of human endothelial nitric oxide synthase. FEBS Lett 1992; 307: 287–93
   PubMed Web of Science ®Google Scholar
• Nunokawa Y, Ishida N, Tanaka S. Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem Biophys Res Commun 1993; 191: 89–94
   PubMed Web of Science ®Google Scholar
• Muruganandam A, Mutus B. Isolation of nitric oxide synthase from human platelets. Biochim Biophys Acta 1994; 1200: 1–6
   PubMed Web of Science ®Google Scholar
• Tayeh M A, Marietta M A. Macrophage oxidation of L-arginine to nitric oxide, nitrite and nitrate. Tetrahydrobiopterin is required as a cofactor. J Biol Chem 1989; 264: 19654–8
   PubMed Web of Science ®Google Scholar
• Stuehr D J, Kwon N S, Nathan C F. FAD and GSH participate in macrophage synthesis of nitric oxide. Biochem Biophys Res Commun 1990; 168: 558–65
   PubMed Web of Science ®Google Scholar
• Palmer R MJ, Moncada S. A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. Biochem Biophys Res Commun 1989; 158: 348–52
   PubMed Web of Science ®Google Scholar
• Knowles R G, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994; 298: 249–58
   PubMed Web of Science ®Google Scholar
• Radomski M W, Palmer R MJ, Moncada S. Glucocorticoids inhibit the expression of an inducible but not the constitutive nitric oxide synthase in vascular endothelial cells. Proc Natl Acad Sci USA 1990; 87: 10043–7
   PubMed Web of Science ®Google Scholar
• Rees D D, Cellek S, Palmer R MJ, Moncada S. Dexa-methasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone. Biochem Biophys Res Commun 1990; 173: 541–7
   PubMed Web of Science ®Google Scholar
• di Rosa M, Radomski M, Camuccio R, Moncada S. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochem Biophys Res Commun 1990; 172: 1246–52
   PubMed Web of Science ®Google Scholar
• Furchgott R F, Vanhoutte P M. Endothelium-derived relaxing and contracting factors. FASEB J 1989; 3: 2007–18
   PubMed Web of Science ®Google Scholar
• Ignarro L J. Signal transduction mechanisms involving nitric oxide. Biochem Pharmacol 1991; 41: 485–90
   PubMed Web of Science ®Google Scholar
• Schmidt H HHW, Lohmann W U. The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. Biochim Biophys Acta 1993; 1178: 153–75
   PubMed Web of Science ®Google Scholar
• Hibbs J R, Jr, Taintor R R, Vavrin Z, . Synthesis of nitric oxide from a terminal guanidino nitrogen atom of L-arginine: a molecular mechanism regulating cellular proliferation that targets intracellular iron. Nitric Oxide from L-arginine: a Bio-regulatory System, S Moncada, E A Higgs, et al. Elsevier, Amsterdam 1990; 189–224
   Google Scholar
• Lepoivre M, Fieschi F, Coves J, Thelander L, Fontecave M. Inactivation of ribonucleotide reductase by nitric oxide. Biochem Biophys Res Commun 1991; 179: 442–8
   PubMed Web of Science ®Google Scholar
• Wink D A, Kasprzak K S, Maragos C M, et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 1991; 254: 1001–3
   PubMed Web of Science ®Google Scholar
• Stamler J S, Simon D I, Osborne J A, et al. S-nitrosylation of proteins with nitric oxide: Synthesis and characterization of biologically active compounds. Proc Natl Acad Sci USA 1992; 89: 444–8
   PubMed Web of Science ®Google Scholar
• Gryglewski R J, Palmer R MJ, Moncada S. Superoxide ion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986; 320: 454–6
   PubMed Web of Science ®Google Scholar
• Beckman J, Tsai J H. Reactions and diffusion of nitric oxide and peroxynitrite. Biochemist 1994; 16: 8–10
   Google Scholar
• Rubanyi G M, Romero J C, Vanhoutte P M. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986; 250: H1145–9
   PubMed Web of Science ®Google Scholar
• Rees D D, Palmer R MJ, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 1989; 86: 3375–8
   PubMed Web of Science ®Google Scholar
• Valiance P, Collier J, Moncada S. Nitric oxide synthesised from L-arginine mediates endothelium-dependent dilatation in human veins. Cardiovasc Res 1989; 23: 1053–7
   Google Scholar
• Radomski M W, Moncada S. Regulation of vascular homeostasis by nitric oxide. Thromb Haemost 1993; 70: 36–41
   PubMed Web of Science ®Google Scholar
• Kubes P, Suzuki M, Granger D N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88: 4651–5
   PubMed Web of Science ®Google Scholar
• Moilanen E, Vuorinen P, Metsä-Ketelä T, Vapaatalo H. Inhibition by nitric oxide donors of human polymorphonuclear leukocyte functions. Br J Pharmacol 1993; 109: 852–8
   PubMed Web of Science ®Google Scholar
• Amezcua J L, Palmer R MJ, de Souza B M, Moncada S. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit. Br J Pharmacol 1989; 97: 1119–24
   PubMed Web of Science ®Google Scholar
• Schulz R, Smith J A, Lewis M J, Moncada S. Nitric oxide synthase in cultured endocardial cells of the pig. Br J Pharmacol 1991; 104: 21–4
   PubMed Web of Science ®Google Scholar
• de Belder A J, Radomski M W, Why H JF, et al. Nitric oxide synthase activities in human myocardium. Lancet 1993; 341: 84–5
   PubMed Web of Science ®Google Scholar
• Balligand J L, Kelly R A, Marsden P A, Smith T W, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signalling system. Proc Natl Acad Sci USA 1993; 90: 347–51
   PubMed Web of Science ®Google Scholar
• Gustafsson L E, Leone A M, Persson M G, Wiklund N P, Moncada S. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. Biochem Biophys Res Commun 1991; 181: 852–7
   PubMed Web of Science ®Google Scholar
• Ward J K, Belvisi M G, Fox A J, et al. Modulation of cholinergic neural bronchoconstriction by endogenous nitric oxide and vasoactive intestinal peptide in human airways in vitro. J Clin Invest 1993; 92: 736–42
   PubMed Web of Science ®Google Scholar
• Tollins J P, Palmer R MJ, Moncada S, Raij L. Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses. Am J Physiol 1990; 258: H655–62
   Google Scholar
• Wilcox C S, Welch W J, Murad F, et al. Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci USA 1992; 89: 11993–7
   PubMed Web of Science ®Google Scholar
• Andersson K E, Persson K. The L-arginine/nitric oxide pathway and non-cholinergic relaxation of the lower urinary tract. Gen Pharmacol 1993; 24: 833–9
   PubMedGoogle Scholar
• Ignarro L J, Bush P A, Buga G M, et al. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle. Biochem Biophys Res Commun 1990; 170: 843–50
   PubMed Web of Science ®Google Scholar
• Bult H, Boeckxstaens G E, Pelckmans P A, et al. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature 1990; 345: 346–7
   PubMed Web of Science ®Google Scholar
• Wiklund N P, Leone A M, Gustafsson L E, Moncada S. Release of nitric oxide evoked by nerve stimulation in guinea-pig intestine. Neuroscience 1993; 53: 607–11
   Google Scholar
• Calignano A, Whittle B JR, di Rosa M, Moncada S. Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo. Eur J Pharmacol 1992; 229: 273–6
   PubMed Web of Science ®Google Scholar
• Hutcheson I R, Whittle B JR, Boughton-Smith N K. Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat. Br J Pharmacol 1990; 101: 815–20
   PubMed Web of Science ®Google Scholar
• Garthwaite J, Charles S L, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988; 336: 385–8
   PubMed Web of Science ®Google Scholar
• Knowles R G, Palacios M, Palmer R MJ, Moncada S. Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc Natl Acad Sci USA 1989; 86: 5159–62
   PubMed Web of Science ®Google Scholar
• Dawson T M, Dawson V L, Snyder S H. A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann Neurol 1992; 32: 297–311
   PubMed Web of Science ®Google Scholar
• Garthwaite J. Nitric oxide signalling in the nervous system. Semin Neurosci 1993; 5: 171–80
   Google Scholar
• Shuman E M, Madison D V. The intercellular messenger nitric oxide is required for long-term potentiation. Science 1991; 254: 1503–6
   Google Scholar
• Shibuki K, Okada D. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature 1991; 349: 326–8
   PubMed Web of Science ®Google Scholar
• Moore P K, Oluyomi A O, Babbedge R C, Wallace P, Hart S L. L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse. Br J Pharmacol 1991; 102: 198–202
   PubMed Web of Science ®Google Scholar
• Kolesnikov Y A, Pick C G, Pasternak G W. NG-nitro-L-arginine prevents morphine tolerance. Eur J Pharmacol 1992; 221: 399–400
   PubMed Web of Science ®Google Scholar
• Duarte I DG, Lorenzetti B B, Ferreira S H. Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Eur J Pharmacol 1990; 186: 289–93
   PubMed Web of Science ®Google Scholar
• Palacios M, Knowles R G, Palmer R MJ, Moncada S. Nitric oxide from L-arginine stimulates the soluble gunaylate cyclase in adrenal glands. Biochem Biophys Res Commun 1989; 165: 802–9
   PubMed Web of Science ®Google Scholar
• Bredt D S, Hwang P M, Snyder S H. Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 1990; 347: 768–70
   PubMed Web of Science ®Google Scholar
• Karanth S, Lyson K, McCann S M. Role of nitric oxide in interleukin 2-induced corticotropin-releasing factor release from incubated hypothalami. Proc Natl Acad Sci USA 1993; 90: 3383–7
   PubMed Web of Science ®Google Scholar
• Schmidt H HHW, Warner T D, Ishii K, Sheng H, Murad F. Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides. Science 1992; 255: 721–3
   PubMed Web of Science ®Google Scholar
• Ischiropoulos H, Zhu L, Beckman J S. Peroxynitrite formation from macrophage-derived nitric oxide. Arch Biochem Biophys 1992; 298: 446–51
   PubMed Web of Science ®Google Scholar
• Weiner C P, Martinez E, Chestnut D H, Ghodsi A. Effect of pregnancy on uterine and carotid artery response to norepinephrine, epinephrine, and phemylephrine in vessels with documented functional endothelium. Am J Obstet Gynecol 1989; 161: 1605–10
   PubMed Web of Science ®Google Scholar
• Weiner C P, Knowles R G, Moncada S. Induction of nitric oxide synthases early in pregnancy. Am J Obstet Gynecol 1994; 171: 838–43
   PubMed Web of Science ®Google Scholar
• Scott-Burden T, Vanhoutte P M. Regulation of vascular smooth muscle cell proliferation: role of endothelium-derived relaxing factor (nitric oxide). J Vase Biol 1991; 3: 445–6
   Google Scholar
• Verbeuren T J, Jordaens F H, Zonnekeyn L L, et al. Effect of hypercholesterolemia on vascular reactivity in rabbits. Circ Res 1986; 58: 552–64
   PubMed Web of Science ®Google Scholar
• Lüscher T F, Tanner F C, Tschudi M R, Noll G. Endothelial dysfunction in coronary artery disease. Annu Rev Med 1993; 44: 395–418
   PubMed Web of Science ®Google Scholar
• Cooke J P, Singer A H, Tsao P, et al. Antiatherogenic effects of L-arginine in the hypercholestorolaemic rabbit. J Clin Invest 1992; 90: 1168–72
   PubMed Web of Science ®Google Scholar
• Calver A, Collier J, Moncada S, Vallance P. Effect of local, intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal. J Hypertens 1992; 10: 1025–31
   PubMed Web of Science ®Google Scholar
• Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992; 339: 572–5
   PubMed Web of Science ®Google Scholar
• Cadwgan T M, Benjamin N. Evidence for altered platelet nitric oxide synthesis in essential hypertension. J Hypertens 1993; 11: 417–20
   PubMed Web of Science ®Google Scholar
• Sarrel P M, Lindsay D C, Poole-Wilson P A, Collins P. Hypothesis: inhibition of endothelium-derived relaxing factor by haemoglobin in the pathogenesis of preeciampsia. Lancet 1990; 336: 1030–2
   PubMedGoogle Scholar
• de Belder A J, Radomski M W. Nitric oxide in the clinical arena. J Hypertens 1994; 12: 617–24
   Google Scholar
• Kilboum R G, Belloni P. Endothelial cell production of nitrogen oxides in response to interferon g in combination with tumor necrosis factor, interleukin-1, or endotoxin. J Natl Cancer Inst 1990; 82: 772–6
   PubMed Web of Science ®Google Scholar
• Schulz R, Nava E, Moncada S. Induction and potential biological relevance of a Ca2+-independent nitric oxide synthase in the myocardium. Br J Pharmacol 1992; 105: 575–80
   PubMed Web of Science ®Google Scholar
• Schulz R, Panas D L, Catena R, et al. The role of nitric oxide in cardiac depression induced by interleukin-1 β and tumour necrosis factor α. Br J Pharmacol 1995; 114: 27–34
   PubMed Web of Science ®Google Scholar
• Corbett J A, Kwon G, Turk J, McDaniel M L. II-1 β induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry 1993; 32: 13767–70
   PubMed Web of Science ®Google Scholar
• Middleton J J, Shorthouse M, Hunter J O. Increased nitric oxide synthesis in ulcerative colitis. Lancet 1993; 341: 465–6
   PubMed Web of Science ®Google Scholar
• Boughton-Smith N K, Evans S M, Hawkey C J, et al. Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet 1993; 342: 338–40
   PubMed Web of Science ®Google Scholar
• Stadler J, Stefanovic-Racic M, Billiar T R, et al. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991; 147: 3915–20
   PubMed Web of Science ®Google Scholar
• Palmer R MJ, Hickery M S, Charles I G, Moncada S, Bayllss M T. Induction of nitric oxide synthase in human chondrocytes. Biochem Biophys Res Commun 1993; 193: 398–405
   PubMed Web of Science ®Google Scholar
• Cattell V, Cook T, Moncada S. Glomeruli synthesize nitrite in experimental nephrotoxic nephritis. Kidney Int 1990; 38: 1056–60
   PubMed Web of Science ®Google Scholar
• Aoki N, Johnson G, III, Lefer A M. Beneficial effects of two forms of NO administration in feline splanchnic artery occlusion shock. Am J Physiol 1990; 258: G275–81
   Google Scholar
• Yamamoto S, Golanov E V, Berger S B, Reis D J. Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J Cereb Blood Flow Metabol 1992; 12: 717–26
   PubMedGoogle Scholar
• Lefer D J, Nakanishi K, Vinten-Johansen J. Endothelial and myocardial cell protection by a cysteine-containing nitric oxide donor after myocardial ischemia and reperfusion. J Cardiovasc Pharmacol 1993; 22(Suppl. 7)S34–43
   Google Scholar
• Patel V C, Yellon D M, Nelld G H, Woolfson R G. Inhibition of nitric oxide limits infarct size in the in situ rabbit heart. Biochem Biophys Res Commun 1993; 194: 234–8
   PubMedGoogle Scholar
• White C R, Brock T A, Chang L Y, et al. Superoxide and peroxynitrite in atherosclerosis. Proc Natl Acad Sci USA 1994; 91: 1044–8
   PubMed Web of Science ®Google Scholar
• Moro M A, Darley-Usmar V M, Goodwin D A, et al. Paradoxical fate and biological action of peroxynitrite on human platelets. Proc Natl Acad Sci USA 1994; 91: 6702–6
   PubMed Web of Science ®Google Scholar
• Villa L M, Salas E, Darley-Usmar V M, Radomski M W, Moncada S. Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc Natl Acad Sci USA 1994; 91: 12383–7
   PubMed Web of Science ®Google Scholar
• Wright C E, Rees D D, Moncada S. Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc Res 1992; 26: 48–57
   PubMed Web of Science ®Google Scholar
• Kilbourn R G, Gross S S, Jubran A, et al. NG-monometyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide. Proc Natl Acad Sci USA 1990; 87: 3629–32
   PubMed Web of Science ®Google Scholar
• Petros A, Lamb G, Leone A, et al. Effects of a nitric oxide synthase inhibitor in humans with spetic shock. Cardiovasc Res 1994; 28: 34–9
   PubMed Web of Science ®Google Scholar
• Berkels R, Klaus W, Boiler M, Rosen R. The calcium modulator nifedipine exerts its antiaggregatory property via a nitric oxide mediated process. Thromb Haemost 1994; 72: 309–12
   PubMed Web of Science ®Google Scholar
• Clozel M, Kuhn H, Hefti F, Baumgartner H R. Effects of angiotensin-converting enzyme inhibitors on endothelial function in hypertension. Biology of Nitric Oxide. 1. Physiological and Clinical Aspects, S Moncada, M A Marietta, J B Hibbs, Jr, E A Higgs. Portland Press, London 1992; 186–7
   Google Scholar
• Rossaint R, Falke K J, Lopez F, et al. Inhaled nitric oxide in adult respiratory distress syndrome. N Engl J Med 1993; 328: 399–405
   PubMed Web of Science ®Google Scholar
• Frostell C, Frataccl M D, Wain J C, Jones R, Zapol W M. A selective pulmonary vasodilator reversing pulmonary vasoconstriction. Circulation 1991; 83: 2038–46
   PubMed Web of Science ®Google Scholar
• Radomski M W. Platelet regulation—another dimension for NO and nitrates. Schwarz Pharma Scientific Forum. Schwarz Pharma, Köln 1994; Vol 7
   Google Scholar
• de Belder A J, Mac Aillster R, Radomski M W, Moncada S, Vallance P J. Effects of S-nitrosoglutathione in the forearm circulation. Evidence for selective inhibition of platelet activation. Cardiovasc Res 1994; 28: 691–4
   PubMed Web of Science ®Google Scholar
• Koshland D E, Jr. The molecule of the year. Science 1992; 258: 1861
   PubMed Web of Science ®Google Scholar
• Feelisch M, Stamler J. Methods in Nitric Oxide (NO) Research. John Wiley and Sons, Chichester 1995
   Google Scholar
• Gryglewski R J, Palmer R MJ, Moncada S. Bioassay of prostacyclin and endothelium-derived relaxing factor (EDRF) from porcine aortic endothelial cells. Br J Pharmacol 1986; 87: 685–94
   PubMed Web of Science ®Google Scholar
• Feelisch M, Noack E A. Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase. Eur J Pharmacol 1987; 139: 19–30
   PubMed Web of Science ®Google Scholar
• Arroyo C, Kohno M. Difficulties encountered in the detection of nitric oxide (NO) by spin trapping techniques. A cautionary note. Free Radic Res Commun 1991; 14: 145–55
   PubMed Web of Science ®Google Scholar
• Knowles R G, Merrett M, Salter M, Moncada S. Differential induction of brain, lung, and liver nitric oxide synthase by endotoxin in the rat. Biochem J 1990; 270: 833–6
   PubMed Web of Science ®Google Scholar
• Springall D R, Riveros-Moreno V, Buttery L, et al. Immunological detection of nitric oxide synthase(s) in human tissues using heterologous antibodies suggesting different isoforms. Histochemistry 1992; 98: 259–66
   PubMedGoogle Scholar
• Jenkins D C, Charles I G, Baylis S, et al. Human colonic adenocarcionoma cell lines show a diverse pattern of nitric oxide synthase gene expression. Br J Cancer 1994; 70: 847–8
   PubMed Web of Science ®Google Scholar
• Malinski T, Taha Z. Nitric oxide release from a single cell measured in situ by a porphyrinic-based microsensor. Nature 1992; 358: 676–7
   PubMed Web of Science ®Google Scholar
• Taha Z, Kiechle F, Malinski T. Oxidation of nitric oxide by oxygen in biological systems monitored by porphyrinic sensor. Biochem Biophys Res Commun 1992; 188: 734–9
   Google Scholar
• Malinski T, Radomski M W, Taha Z, Moncada S. Direct electrochemical measurement of nitric oxide released from human platelets. Biochem Biophys Res Commun 1993; 194: 960–5
   PubMed Web of Science ®Google Scholar
• Malinski T, Bailey F, Taha Z, Kapturczak M, Kiechle F, Radomski M W. In vivo determination of nitric oxide by a porphyrinic microsensor. Endothelium 1993, Suppl 1: 55
   Google Scholar
• Thomsen L L, Lawtin F G, Knowles R G, et al. Nitric oxide synthase activity in human gynecological cancer. Cancer Res 1994; 54: 1352–4
   PubMed Web of Science ®Google Scholar
• Radomski M W, Jenkins D C, Holmes L, Moncada S. Human colorectal adenocarcinoma cells: differential nitric oxide synthase determines their ability to aggregate platelets. Cancer Res 1991; 51: 6073–8
   PubMed Web of Science ®Google Scholar
• Dong Z, Staroselsky A H, Qi X, Xie K, Fiedler I J. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. Cancer Res 1994; 54: 789–93
   PubMed Web of Science ®Google Scholar