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Annals of Medicine Volume 29, 1997 - Issue 2
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Editorial

Do We Need Adjuvant Treatment for Rectal Cancer?

Rune Sjödahl Department of Surgery, University Hospital, Linköping, Sweden
Pages 91-93 | Published online: 30 Oct 2013

References

  • Swedish Rectal Cancer Trial. Preoperative radiotherapy improves survival in resectable rectal carcinoma final report from a nationwide Swedish trial. N Engl J Med (In press).
  • Gerard A, Buyse M, Nordlinger B, et al. Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organisa­tion for Research and Treatment of Cancer (EORTC). Ann Surg 88; 208: 606–14.
  • Cedermark B, Johansson H, Rutqvist L-E, Wilking N, The Stockholm Colorectal Cancer Study Group. The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma. A prospective randomized trial. Cancer 95; 75: 2269-75.
  • Swedish Rectal Cancer Trial. Initial report from a Swedish multicenter study examining the role of preoperative irradi­ation in the treatment of patients with resectable rectal carcinoma. Br J Surg 93; 80: 1333-6.
  • Holm T, Singnomklau T, Rutqvist L-E, Cedermark B. Adjuvant preoperative radiotherapy in patients with rectal carcinoma. Adverse effects during long term follow-up of two randomized trials. Cancer 96; 78: 968–76.
  • Moertel CG, Fleming TR, MacDonald JS, et al. Fluoro-uracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med 95; 122:321–6.
  • NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA 90; 264: 1444-50.
  • IMPACT (International Multicentre Pooled Analysis of Colon Cancer Trials) Investigators. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 95; 345: 939–44.
  • Krook JE, Moertel CG, Gunderson LL, et al. Effective surgical adjuvant therapy for high risk rectal carcinoma. N Engl J Med 91 ; 324: 709–15.
  • Riethmiiller G, Schneider-Gadicke E, Schlimok G, et al. for The German Cancer Aid 17-1A Study Group. Randomized trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. Lancet 94; 343: 1177-83.
  • Mac-Farlane JK, Ryall RDH, Heald RJ. Mesorectal excision for rectal cancer. Lancet 93; 341: 457–60.
  • Adam I J, Mohamdee MO, Martin IG, et al. Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 94; 344: 707–11.
  • Enker WE, Thaler HT, Cranor ML, Polyak T. Total meso­rectal excision in the operative treatment of rectal cancer. J Am Coll Surg 95; 181: 335–46.
  • Arbman G, Nilsson E, Hallbõõk O, Sjõdahl R. Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 96; 83: 375–9.

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