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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 40, 2011 - Issue 6
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Research Article

Efficacy of Recombinant Human Mannose Binding Lectin Alone and in Combination with Itraconazole Against Murine Candida albicans vaginitis

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Pages 553-568 | Published online: 21 Apr 2011

REFERENCES

  • Babula, O., Lazdane, G., Kroica, J., Ledger, W. J., Witkin, S. S. (2003). Relation between recurrent vulvovaginal candidiasis, vaginal concentrations of mannose-binding lectin, and a mannose-binding lectin gene polymorphism in Latvian women. Clin. Infect. Dis. 37: 733–737.
  • Brouwer, N., Dolman, K. M., van Houdt, M., Sta, M., Roos, D., Kuijpers, T. W. (2008). Mannose-Binding Lectin (MBL) facilitates opsonophagocytosis of yeasts but not of bacteria despite MBL binding. J. Immunol. 180:4124–4132.
  • Brummer, E., Stevens, D. A. (2010). Collectins and fungal pathogens: role of surfactant proteins and mannose binding lectin in host resistance. Med. Mycol. 48:16–28.
  • Calderon, L., Williams, R., Martinez, M., Clemons, K. V., Stevens, D. A. (2003). Genetic susceptibility to vaginal candidiasis. Med. Mycol. 41:143–147.
  • Capilla, J., Clemons, K. V., Stevens, D. A. (2007). Animal models: an important tool in mycology. Med. Mycol. 45:657–684.
  • Christiansen, O. B., Kilpatrick, D. C., Souter, V., Varming, K., Thiel, S., Jensenius, J. C. (1999). Mannan-binding lectin deficiency is associated with unexplained recurrent miscarriage. Scand. J. Immunol. 49:193–196.
  • Clemons, K. V., Gonzalez, G. M., Singh, G., Imai, J., Espiritu, M., Parmar, R., Stevens, D. A. (2006). Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs. Antimicrob. Agents Chemother. 50:2650–2657.
  • Clemons, K. V., Spearow, J. L., Parmar, R., Espiritu, M., Stevens, D. A. (2004). Genetic susceptibility of mice to Candida albicans vaginitis correlates with host estrogen sensitivity. Infect. Immun. 72:4878–4880.
  • Donders, G. G., Babula, O., Bellen, G., Linhares, I. M., Witkin, S. S. (2008). Mannose-binding lectin gene polymorphism and resistance to therapy in women with recurrent vulvovaginal candidiasis. B.J.O.G. 115:1225–1231.
  • Eisen, D. P., Minchinton, R. M. (2003). Impact of mannose-binding lectin on susceptibility to infectious diseases. Clin. Infect. Dis. 37:1496–1505.
  • Frakking, F. N., Brouwer, N., van de Wetering, M. D., Budde, I. K., Strengers, P. F., Huitema, A. D., Laursen, I., Houen, G., Caron, H. N., Dolman, K. M., Kuijpers, T. W. (2009). Safety and pharmacokinetics of plasma-derived mannose-binding lectin (MBL) substitution in children with chemotherapy-induced neutropaenia. Eur. J. Cancer 45:505–512.
  • Ip, W. K., Lau, Y. L. (2004). Role of mannose-binding lectin in the innate defense against Candida albicans: enhancement of complement activation, but lack of opsonic function, in phagocytosis by human dendritic cells. J. Infect. Dis. 190:632–640.
  • Jensenius, J. C., Jensen, P. H., McGuire, K., Larsen, J. L., Thiel, S. (2003). Recombinant mannan-binding lectin (MBL) for therapy. Biochem. Soc. Transact. 31:763–767.
  • Lee, S. J., Gonzalez-Aseguinolaza, G., Nussenzweig, M. C. (2002). Disseminated candidiasis and hepatic malarial infection in mannose-binding-lectin-A-deficient mice. Mol. Cell. Biol. 22:8199–8203.
  • Lee, S. J., Zheng, N. Y., Clavijo, M., Nussenzweig, M. C. (2003). Normal host defense during systemic candidiasis in mannose receptor-deficient mice. Infect. Immun. 71:437–445.
  • Lillegard, J. B., Sim, R. B., Thorkildson, P., Gates, M. A., Kozel, T. R. (2006). Recognition of Candida albicans by mannan-binding lectin in vitro and in vivo. J. Infect. Dis. 193:1589–1597.
  • Liu, F., Liao, Q., Liu, Z. (2006). Mannose-binding lectin and vulvovaginal candidiasis. Int. J. Gynaecol. Obstet. 92:43–47.
  • Liu, H., Jensen, L., Hansen, S., Petersen, S. V., Takahashi, K., Ezekowitz, A. B., Hansen, F. D., Jensenius, J. C., Thiel, S. (2001). Characterization and quantification of mouse mannan-binding lectins (MBL-A and MBL-C) and study of acute phase responses. Scand. J. Immunol. 53:489–497.
  • Pellis, V., De Seta, F., Crovella, S., Bossi, F., Bulla, R., Guaschino, S., Radillo, O., Garred, P., Tedesco, F. (2005). Mannose binding lectin and C3 act as recognition molecules for infectious agents in the vagina. Clin. Exp. Immunol. 139:120–126.
  • Petersen, K. H. Matthiesen, F., Agger, T., Kongerslev, L., Thiel, S., Cornelissen, K., Axelsen, M. (2006). Phase I safety, tolerability, and pharmacokinetic study of recombinant human mannan-binding lectin. J. Clin. Immunol. 26: 564–575.
  • Petersen, S. V., Thiel, S., Jensen, L., Vorup-Jensen, T., Koch, C., Jensenius, J. C. (2000). Control of the classical and the MBL pathway of complement activation. Mol. Immunol. 37:803–811.
  • Shi, L., Takahashi, K., Dundee, J., Shahroor-Karni, S., Thiel, S., Jensenius, J. C., Gad, F., Hamblin, M. R., Sastry, K. N., Ezekowitz, R. A. (2004). Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J. Exp. Med. 199: 1379–1390.
  • Stevens, D. A., Brummer, E., Clemons, K. V. (2006). Interferon-gamma as an antifungal. J. Infect. Dis. 194(Suppl 1): S33–37.
  • Stevens, D. A., Calderon, L., Martinez, M., Clemons, K. V., Wilson, S. J., Selitrennikoff, C. P. (2002). Zeamatin, clotrimazole and nikkomycin Z in therapy of a Candida vaginitis model. J. Antimicrob. Chemother. 50: 361–364.
  • Sugar, A. M., Brummer, E., Stevens, D. A. (1983). Murine pulmonary macrophages: evaluation of lung lavage fluids, miniaturized monolayers, and candidacidal activity. Am. Rev. Respir. Dis. 127: 110–112.
  • Thiel, S., Frederiksen, P. D., Jensenius, J. C. (2006). Clinical manifestations of mannan-binding lectin deficiency. Mol. Immunol. 43: 86–96.

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