Publication Cover
Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 40, 2011 - Issue 6
306
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Expression of Th17 and Treg Lymphocyte Subsets in Hypertrophied Adenoids of Children and its Clinical Significance

, , , &
Pages 657-666 | Published online: 04 May 2011

REFERENCES

  • Aujla, S. J., Chan, Y. R., Zheng, M., Fei, M., Askew, D. J., Pociask, D. A., Reinhart, T. A., McAllister, F., Edeal, J., Gaus, K., . (2008). IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14: 275–281.
  • Bauer, I., Hassmann-Poznanska, E., Wysocka, J., Kasprzycka, E., Ratomski, K. (2008). Adenoid as a source of lymphocytes in the surface secretions of nasopharynx. Int. J. Pediatr. Otorhinolaryngol. 72:321–326.
  • Ben-Yaakov, A., Maly, B., Abu-Ita, R., Elidan, J., Gross, M. (2010). Identification and immunolocalization of the innate immune receptor CD14 in hypertrophic adenoids and tonsils. Immunol Invest. Posted online on November 10.
  • Bluestone CD (1992). Current indications for tonsillectomy and adenoidectomy. Ann. Otol. Rhinol. Laryngol. Suppl. 155:58–64.
  • Brenchley, J. M., Paiardini, M., Knox, K. S., Asher, A. I., Cervasi, B., Asher, T. E., Scheinberg, P., Price, D. A., Hage, C. A., Kholi, L. M., . (2008). Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112:2826–2835.
  • Brodsky, L., Koch, R. J. (1993). Bacteriology and immunology of normal and diseased adenoids in children. Arch. Otolaryngol. Head Neck Surg. 119:821–829.
  • Cheng, X., Yu, X., Ding, Y. J., Fu, Q. Q., Xie, J. J., Tang, T. T., Yao, R., Chen, Y., Liao, Y. H. (2008). The Th17/Treg imbalance in patients with acute coronary syndrome. Clin. Immunol. 127:89–97.
  • Eastaff-Leung, N., Mabarrack, N., Barbour, A., Cummins, A., Barry, S. (2010). Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease. J. Clin. Immunol. 30:80–89.
  • Eyerich, K., Foerster, S., Rombold, S., Seidl, H. P., Behrendt, H., Hofmann, H., Ring, J., Traidl-Hoffmann, C. (2008). Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22. J. Invest. Dermatol. 128:2640–2645.
  • Favre, D., Lederer, S., Kanwar, B., Ma, Z. M., Proll, S., Kasakow, Z., Mold, J., Swainson, L., Barbour, J. D., Baskin, C. R., . (2009). Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog. 5: e1000295.
  • Franco, R. A., Rosenfeld, R. M., Rao, M. (2000). Quality of life for children with obstructive sleep apnea. Otolaryngol. Head Neck Surg. 123:9–16.
  • Huang, W., Na, L., Fidel, P. L., Schwarzenberger, P. (2004). Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J. Infect. Dis. 190:624–631.
  • Ishigame, H., Kakuta, S., Nagai, T., Kadoki, M., Nambu, A., Komiyama, Y., Fujikado, N., Tanahashi, Y., Akitsu, A., Kotaki, H., . (2009). Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30:108–119.
  • Jia, S., Li, C., Wang, G., Yang, J., Zu, Y. (2010). The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease. Clin. Exp. Immunol. 162:131–137.
  • Koenen, H. J., Smeets, R. L., Vink, P. M., van Rijssen, E., Boots, A. M., Joosten, I. (2008). Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 112:2340–2352.
  • Lagging, E., Papatziamos, G., Hallden, G., Hemlin, C., Harfast, B., van Hage-Hamsten, M. (1998). T-cell subsets in adenoids and peripheral blood related to age, otitis media with effusion and allergy. Apmis 106:354–360.
  • Langier, S., Sade, K., Kivity, S. (2010). Regulatory T cells: the suppressor arm of the immune system. Autoimmun. Rev. 10:112–115.
  • Louten, J., Boniface, K., de Waal Malefyt, R. (2009). Development and function of TH17 cells in health and disease. J. Allergy Clin. Immunol. 123:1004–1011.
  • Ma, J., Yu, J., Tao, X., Cai, L., Wang, J., Zheng, S. G. (2010). The imbalance between regulatory and IL-17-secreting CD4+ T cells in lupus patients. Clin. Rheumatol. 29:1251–1258.
  • Mattila, P. S., Tarkkanen, J. (1996). B- and T-lymphocyte subpopulations in the adenoids of children with otitis media. APMIS 104:698–704.
  • Olivito, B., Simonini, G., Ciullini, S., Moriondo, M., Betti, L., Gambineri, E., Cantarini, L., De Martino, M., Azzari, C., Cimaz, R. (2009). Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritis. J. Rheumatol. 36:2017–2024.
  • Papatziamos, G., van der Ploeg, I., Hemlin, C., Patwardhan, A., Scheynius, A. (1999). Increased occurrence of IgE+ and FcepsilonRI+ cells in adenoids from atopic children. Allergy 54:916–925.
  • Papatziamos, G., van Hage-Hamsten, M., Halden, G., Lundahl, J., Hemlin, C. (2003). Increased levels of IL-2 and IL-4 in stimulated adenoidal lymphocytes of atopic children. Int. Arch. Allergy Immunol. 132:329–335.
  • Rong, G., Zhou, Y., Xiong, Y., Zhou, L., Geng, H., Jiang, T., Zhu, Y., Lu, H., Zhang, S., Wang, P., . (2009). Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: The serum cytokine profile and peripheral cell population. Clin. Exp. Immunol. 156:217–225.
  • Rosenfeld, R. M., Green, R. P. (1990). Tonsillectomy and adenoidectomy: changing trends. Ann. Otol. Rhinol. Laryngol. 99:187–191.
  • Sakaguchi, S., Miyara, M., Costantino, C. M., Hafler, D. A. (2010). FOXP3+ regulatory T cells in the human immune system. Nat. Rev. Immunol. 10:490–500.
  • Shao, X. S., Yang, X. Q., Zhao, X. D., Li, Q., Xie, Y. Y., Wang, X. G., Wang, M., Zhang, W. (2009). The prevalence of Th17 cells and FOXP3 regulate T cells (Treg) in children with primary nephrotic syndrome. Pediatr. Nephrol. 24:1683–1690.
  • Shi, Y., Wang, H., Su, Z., Chen, J., Xue, Y., Wang, S., Xue, Y., He, Z., Yang, H., Zhou, C., . (2010). Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto’s thyroiditis. Scand. J. Immunol. 72:250–255.
  • Shin, S. Y., Choi, S. J., Hur, G. Y., Lee, K. H., Kim, S. W., Cho, J. S., Park, H. S. (2009). Local production of total IgE and specific antibodies to the house dust mite in adenoid tissue. Pediatr. Allergy Immunol. 20:134–141.
  • Smith, S. L., Pereira, K. D. (2007). Tonsillectomy in children: indications, diagnosis and complications. ORL J. Otorhinolaryngol. Relat. Spec. 69:336–339.
  • Voo, K. S., Wang, Y. H., Santori, F. R., Boggiano, C., Wang, Y. H., Arima, K., Bover, L., Hanabuchi, S., Khalili, J., Marinova, E., . (2009). Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc. Natl. Acad. Sci. USA 106:4793–4798.
  • Wysocka, J., Hassmann, E., Kasprzycka, E., Musiatowicz, M., Lipska, A. (2002). Lymphocyte subpopulations in hypertrophied adenoid in children with otitis media with effusion. Rocz. Akad. Med. Bialymst. 47:105–112.
  • Wysocka, J., Hassmann, E., Lipska, A., Musiatowicz, M. (2003). Naive and memory T cells in hypertrophied adenoids in children according to age. Int. J. Pediatr. Otorhinolaryngol. 67:237–241.
  • Zelazowska-Rutkowska, B., Wysocka, J., Skotnicka, B. (2010). Chosen factors of T and B cell apoptosis in hypertrophic adenoid in children with otitis media with effusion. Int. J. Pediatr. Otorhinolaryngol. 74:698–700.
  • Zhang, J., Hua, G., Zhang, X., Tong, R., Du, X., Li, Z. (2010). Regulatory T cells/T-helper cell 17 functional imbalance in uraemic patients on maintenance haemodialysis: a pivotal link between microinflammation and adverse cardiovascular events. Nephrology (Carlton) 15:33–41.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.