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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 41, 2012 - Issue 8
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Research Article

The Tie2 Receptor Antagonist Angiopoietin-2 in Systemic Lupus Erythematosus: Its Correlation with Various Disease Activity Parameters

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Pages 864-875 | Published online: 18 Sep 2012

REFERENCES

  • Aird, W.C. (2005). Spatial and temporal dynamics of the endothelium. J. Thromb Haemost. 3:392–406.
  • Belmont, H.M., Abramson, S.B., Lie, J.T. (1996). Pathology and pathogenesis of vascular injury in systemic lupus erythematosus. Interactions of inflammatory cells and activated endothelium. Arthritis Rheum. 39:9–22.
  • Bogdanovic, E., Nguyen, V.P., Dumont, D.J. (2006). Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization. J. Cell Sci. 119: 3551–3560.
  • Bonfanti, R., Furie, B.C., Furie, B., Wagner, D.D. (1989). PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells. Blood 73: 1109–1112.
  • Brkovic, A., Pelletier, M., Girard, D., Sirois, M.G. (2007). Angiopoietin chemotactic activities on neutrophils are regulated by PI-3K activation. J. Leukoc. Biol. 81:1093–1101.
  • Chen, M., Geng, J.G. (2006). P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis. Arch. Immunol. Ther. Exp. (Warsz); 54:75–84.
  • Davis, B., Dei, C.A., Long, D.A., (2007). Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J. Am. Soc. Nephrol. 18:2320–2329.
  • El-Banawy, H.S., Gaber, E.W., Maharem, D.A., Matrawy, K.A. (2011). Angiopoietin-2, endothelial dysfunction and renal involvement in patients with systemic lupus erythematosus. J. Nephrol. 23:1. doi: 10.5301/jn.5000030. [Epub ahead of print]
  • Fiedler, U., Augustin, H.G. (2006). Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol. 27:552–558.
  • Fiedler, U., Reiss, Y., Scharpfenecker, M., (2006). Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat. Med. 12:235–239.
  • Gladman, D., Dafna, D., Dominique, I., Murray, B.U. (2002). Systemic Lupus Erythematosus Disease Activity Index 2000. J. Rheumatol. 29:288–291.
  • Gladman, D., Klippel, J., Liang, M., (1999). Guidelines for referral and management of SLE in adults. Arthritis Rheum. 42(9):1785.
  • Harfouche, R., Gratton, J.P., Yancopoulos, G.D., Noseda, M., Karsan, A., Hussain, S.N. (2003). Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases. FASEB J. 17:1523–1525.
  • Harfouche, R., Hussain, S.N. (2006). Signaling and regulation of endothelial cell survival by angiopoietin-2. Am. J. Physiol. Heart Circ. Physiol. 291: H1635–H1645.
  • Jones, N., Iljin, K., Dumont, D.J., Alitalo, K. (2001). Tie receptors: New modulators of angiogenic and lymphangiogenic responses. Nat. Rev. Mol. Cell Biol. 2:257–267.
  • Kumpers, P., David, S., Haubitz, M., Hellpap, J., Horn, R., Brocker, V., Schiffer, M., Haller, H., Witte, T. (2009). The Tie2 receptor antagonist angiopoietin 2 facilitates vascular inflammation in systemic lupus erythematosus. Ann. Rheum. Dis. 68:1638–1643.
  • Lemieux, C., Maliba, R., Favier, J., Theoret, J.F., Merhi, Y., Sirois, M.G. (2005). Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses. Blood 105:1523–1530.
  • Lorant, D.E., Patel, K.D., McIntyre, T.M., McEver, R.P., Prescott, S.M., Zimmerman, G.A. (1991). Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: A juxtacrine system for adhesion and activation of neutrophils. J. Cell Biol. 115:223–234.
  • Lukasz, A., Hellpap, J., Horn, R., Kielstein, J., David, S., Haller, H., Kumpers, P. (2008). Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays. Crit. Care 12:R94.
  • Lu, Y.H., Deng, A.G., Li, N., (2006). Changes in angiopoietin expression in glomeruli involved in glomerulosclerosis in rats with daunorubicin-induced nephrosis. Acta Pharmacol Sin. 27:579–587.
  • Maisonpierre, P.C., Suri, C., Jones, P.F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T.H., Papadopoulos, N., Daly, T.J., Davis, S., Sato, T.N., Yancopoulos, G.D. (1997). Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277:55–60.
  • Maliba, R., Lapointe, S., Neagoe, P.E., Brkovic, A., Sirois, M.G. (2006). Angiopoietins-1 and -2 are both capable of mediating endothelial PAF synthesis: intracellular signaling pathways. Cell. Signal. 18:1947–1957.
  • Orfanos, J., Kotanidou, M., Glynos, H., (2007).: Angiopoietin-2 is increased in severe sepsis: Correlation with inflammatory mediators Crit. Care Med. 35(1):1699–1700.
  • Peter, C. (2000). Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6: 389–395.
  • Petri, M. (2005). Review of classification criteria for systemic lupus erythematosus. Rheum Dis Clin. North Am. 31(2):245–254.
  • Rollin, S., Lemieux, C., Maliba, R., Favier, J., Villeneuve, L.R., Allen, B.G., Soker, S., Bazan, N.G., Merhi, Y., Sirois, M.G. (2004). VEGF mediated endothelial P-selectin translocation: Role of VEGF receptors and endogenous PAF synthesis. Blood 103:3789–3797.
  • Roviezzo, F., Tsigkos, S., Kotanidou, A., Bucci, M., Brancaleone, V., Cirino, G., Papapetropoulos, A. (2005). Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage. J. Pharmacol. Exp. Ther. 314:738–744.
  • Thurston, G., Suri, C., Smith, K., McClain, J., Sato, T.N., Yancopoulos, G.D., McDonald, D.M. (1999). Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286:2511–2514.
  • Parikh, S.M., Mammoto, T., Schultz, A., (2006). Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. PLOS Med. 3:e46.
  • Pigott, R., Power, C. (1993). Human soluble P-Selectin/CD62P Immunoassay in the Adhesion Molecule Facts Book. Academic Press; 2 edition (September 5, 2000). p. 132.

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