References
- Ambros V. (2003). MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell, 113, 673–6
- Becker KG. (1999). Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways? Diabetes, 48, 1353–8
- Becker KG. (2004). The common variants/multiple disease hypothesis of common complex genetic disorders. Med Hypotheses, 62, 309–17
- Castanotto D, Rossi JJ. (2009). The promises and pitfalls of RNA-interference-based therapeutics. Nature, 457, 426–33
- Chassin C, Kocur M, Pott J, et al. (2010). miR-146a mediates protective innate immune tolerance in the neonate intestine. Cell Host Microbe, 8, 358–68
- Chatzikyriakidou A, Voulgari PV, Georgiou I, Drosos AA. (2010). A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility. Joint Bone Spine, 77, 411–3
- Curtale G, Citarella F, Carissimi C, et al. (2010). An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Blood, 115, 265–73
- Davis MP, Abreu-Goodger C, van Dongen S, et al. (2012). Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines. PLoS One, 7, e41762 . doi: 10.1371/journal.pone.0041762.
- Duan R, Pak C, Jin P. (2007). Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet, 16, 1124–31
- Fenoglio C, Cantoni C, De Riz M, et al. (2011). Expression and genetic analysis of miRNAs involved in CD4+ cell activation in patients with multiple sclerosis. Neurosci Lett, 504, 9–12
- Han J, Lee Y, Yeom KH, et al. (2006). Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell, 125, 887–901
- Hashemi M, Eskandari-Nasab E, Zakeri Z, et al. (2012). Association of pre-miRNA-146a rs2910164 and premiRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis. Mol Med Rep . doi:10.3892/mmr.2012.1176
- Hou J, Wang P, Lin L, et al. (2009). MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J Immunol, 183, 2150–8
- Jazdzewski K, Liyanarachchi S, Swierniak M, et al. (2009). Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proc Natl Acad Sci USA, 106, 1502–5
- Jazdzewski K, Murray EL, Franssila K, et al. (2008). Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci USA, 105, 7269–74
- Jimenez-Morales S, Gamboa-Becerra R, Baca V, et al. (2012). MiR-146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients. Tissue Antigens, 80, 317–21
- Krek A, Grun D, Poy MN, et al. (2005). Combinatorial microRNA target predictions. Nat Genet, 37, 495–500
- Labbaye C, Spinello I, Quaranta MT, et al. (2008). A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis. Nat Cell Biol, 10, 788–801
- Li Y, Vandenboom TG, 2nd, Wang Z, et al. (2010). miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res, 70, 1486–95
- Lin SL, Chiang A, Chang D, Ying SY. (2008). Loss of mir-146a function in hormone-refractory prostate cancer. RNA, 14, 417–24
- Lofgren SE, Frostegard J, Truedsson L, et al. (2012). Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene. Genes Immun, 13, 268–74
- Lu LF, Boldin MP, Chaudhry A, et al. (2010). Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell, 142, 914–29
- Luo X, Yang W, Ye DQ, et al. (2011). A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet, 7, e1002128 . doi: 10.1371/journal.pgen.1002128
- Marrack P, Kappler J, Kotzin BL. (2001). Autoimmune disease: why and where it occurs. Nat Med, 7, 899–905
- Park S, Kang S, Min KH, et al. (2013). Age-associated changes in microRNA expression in bone marrow derived dendritic cells. Immunol Invest, 42, 179–90
- Pauley KM, Cha S, Chan EK. (2009). MicroRNA in autoimmunity and autoimmune diseases. J Autoimmun, 32, 189–94
- Pauley KM, Satoh M, Chan AL, et al. (2008). Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther, 10, R101 . doi: 10.1186/ar2493
- Qian L, Gao DW, Wang GS, et al. (2012). Relationship between the single nucleotide polymorphisims in pre-miR-146a rs2910164 and expression of miR-146a in rheumatoid arthritis. Chin J Microbiol Immunol, 32, 253--7
- Rusca N, Monticelli S. (2011). MiR-146a in immunity and disease. Mol Biol Int, 2011, 437301 . doi: 10.4061/2011/437301
- Sakoguchi A, Jinnin M, Makino T, et al. (2013). The miR-146a rs2910164 C/G polymorphism is associated with telangiectasia in systemic sclerosis. Clin Exp Dermatol, 38, 99–100
- Saunders MA, Liang H, Li WH. (2007). Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci USA, 104, 3300–5
- Schmidt CW. (2011). Questions persist: environmental factors in autoimmune disease. Environ Health Perspect, 119, A249–53
- Sonkoly E, Wei T, Janson PC, et al. (2007). MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One, 2, e610
- Suzuki A, Yamada R, Chang X, et al. (2003). Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet, 34, 395–402
- Taganov KD, Boldin MP, Chang KJ, Baltimore D. (2006). NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA, 103, 12481–6
- Vyse TJ, Todd JA. (1996). Genetic analysis of autoimmune disease. Cell, 85, 311–8
- Xu B, Feng NH, Li PC, et al. (2010). A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo. Prostate, 70, 467–72
- Yang B, Zhang JL, Shi YY, et al. (2011). Association study of single nucleotide polymorphisms in pre-miRNA and rheumatoid arthritis in a Han Chinese population. Mol Biol Rep, 38, 4913–9
- Zhang H, Pu J, Wang X, et al. (2013). IRAK1 rs3027898 C/A polymorphism is associated with risk of rheumatoid arthritis. Rheumatol Int, 33, 369–75
- Zhang J, Yang B, Ying B, et al. (2011). Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus. Mol Biol Rep, 38, 1463–8
- Zhou Q, Hou S, Liang L, et al. (2012). MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome. Ann Rheum Dis [Epub ahead of print]