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Sperm Protein17 is an Oncofetal Antigen: A Lesson From a Murine Model

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Pages 367-374 | Accepted 01 Apr 2014, Published online: 08 May 2014

REFERENCES

  • Richardson RT, Yamasaki N, O'Rand MG. Sequence of a rabbit sperm zona pellucida binding protein and localization during the acrosome reaction. Dev Biol 1994;165:688–701.
  • Chiriva-Internati M, Gagliano N, Donetti E, Sperm protein 17 is expressed in the sperm fibrous sheath. J Transl Med 2009;7:61.
  • Fenderson BA, Toshimori K, Muller CH, Identification of a protein in the fibrous sheath of the sperm flagellum. Biol Reprod 1988;38:345–357.
  • Eddy EM, Toshimori K, O'Brien DA. Fibrous sheath of mammalian spermatozoa. Microsc Res Tech 2003;61:103–115.
  • Eddy EM. The scaffold role of the fibrous sheath. Soc Reprod Fertil Suppl 2007;65:45–62.
  • Fawcett DW. The mammalian spermatozoon. Dev Biol 1975;44:394–436.
  • Lindemann CB, Orlando A, Kanous KS. The flagellar beat of rat sperm is organized by the interaction of two functionally distinct populations of dynein bridges with a stable central axonemal partition. J Cell Sci 1992;102:249–260.
  • Vijayaraghavan S, Liberty GA, Mohan J, Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein. Mol Endocrinol 1999;13:705–717.
  • Mandal A, Naaby-Hansen S, Wolkowicz MJ, FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa. Biol Reprod 1999;61:1184–1197.
  • Fulcher KD, Mori C, Welch JE, Characterization of Fsc1 cDNA for a mouse sperm fibrous sheath component. Biol Reprod 1995;52:41–49.
  • Fujita A, Nakamura K, Kato T, Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella. J Cell Sci 2000;113:103–112.
  • Nakamura K, Fujita A, Murata T, Rhophilin, a small GTPase Rho-binding protein, is abundantly expressed in the mouse testis and localized in the principal piece of the sperm tail. FEBS Lett 1999;445:9–13.
  • Dong G, Loukinova E, Smith CW, Genes differentially expressed with malignant transformation and metastatic tumor progression of murine squamous cell carcinoma. J Cell Biochem Suppl. 1997;28–29:90–100.
  • Chiriva-Internati M, Wang Z, Salati E, Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma. Blood 2002;100:961–965.
  • Straughn JM, Jr., Shaw DR, Guerrero A, Expression of sperm protein 17 (Sp17) in ovarian cancer. Int J Cancer: Journal international du cancer. 2004;108:805–811.
  • Chiriva-Internati M, Grizzi F, Weidanz JA, A NOD/SCID tumor model for human ovarian cancer that allows tracking of tumor progression through the biomarker Sp17. J Immunol Methods 2007;321:86–93.
  • Chiriva-Internati M, Wang Z, Salati E, Tumor vaccine for ovarian carcinoma targeting sperm protein 17. Cancer 2002;94:2447–2453.
  • Chiriva-Internati M, Yu Y, Mirandola L, Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer. PLoS One 2010;5:0010471.
  • Chiriva-Internati M. Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond. Int Rev Immunol 2011;30:138–149.
  • Chiriva-Internati M, Mirandola L, Kast WM, Understanding the cross-talk between ovarian tumors and immune cells: mechanisms for effective immunotherapies. Int Rev Immunol 2011;30:71–86.
  • Gupta G, Sharma R, Chattopadhyay TK, Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer. Int J Cancer Journal international du cancer. 2007;120:1739–1747.
  • Li FQ, Liu Q, Han YL, Sperm protein 17 is highly expressed in endometrial and cervical cancers. BMC Cancer 2010;10:429.
  • Bumm K, Grizzi F, Franceschini B, Sperm protein 17expression defines 2 subsets of primary esthesioneuroblastoma. Hum Pathol 2005;36:1289–1293.
  • Grizzi F, Gaetani P, Franceschini B, Sperm protein 17 is expressed in human nervous system tumours. BMC Cancer 2006;6:23.
  • De Jong A, Buchli R, Robbins D. Characterization of sperm protein 17 in human somatic and neoplastic tissue. Cancer Lett 2002;186(2):201–209.
  • Li FQ, Han YL, Liu Q, Overexpression of human sperm protein 17 increases migration and decreases the chemosensitivity of human epithelial ovarian cancer cells. BMC Cancer 2009;9:323.
  • Lacy HM, Sanderson RD. Sperm protein 17 is expressed on normal and malignant lymphocytes and promotes heparan sulfate-mediated cell–cell adhesion. Blood 2001;98:2160–2165.
  • Zendman AJ, Ruiter DJ, Van Muijen GN. Cancer/testis-associated genes: identification, expression profile, and putative function. J Cell Physiol 2003;194:272–288.
  • Scanlan MJ, Simpson AJ, Old LJ. The cancer/testis genes: review, standardization, and commentary. Cancer Immun 2004;4:1.
  • Simpson AJ, Caballero OL, Jungbluth A, Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer 2005:615–625.
  • Chang TC, Yang Y, Yasue H, The expansion of the PRAME gene family in Eutheria. PLoS One 2011;6:0016867.
  • Gurchot C. The trophoblast theory of cancer (John Beard, 1857–1924) revisited. Oncology 1975;31:310–333.
  • Moss RW. The life and times of John Beard, DSc (1858–1924). Integr Cancer Ther 2008;7:229–251.
  • Burleigh AR. Of germ cells, trophoblasts, and cancer stem cells. Integr Cancer Ther 2008;7:276–281.
  • Moss RW. An annotated bibliography of works by John Beard: Integr Cancer Ther 2008;7(4):317–321.
  • Simpson AJ, Caballero OL, Jungbluth A, Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer 2005;5:615–625.
  • Kalejs M, Erenpreisa J. Cancer/testis antigens and gametogenesis: a review and “brain-storming” session. Cancer Cell Int 2005;5:4.
  • Scanlan MJ, Simpson AJ, Old LJ. The cancer/testis genes: review, standardization, and commentary. Cancer Immun 2004;4:1.
  • Old LJ. Cancer/testis (CT) antigens—a new link between gametogenesis and cancer. Cancer Immun 2001;1:1.
  • Wen Y, Richardson RT, Widgren EE, O'Rand MG. Characterization of Sp17: a ubiquitous three domain protein that binds heparin. Biochem J 2001;357:25–31.
  • Newell AE, Fiedler SE, Ruan JM, Protein kinase A RII-like (R2D2) proteins exhibit differential localization and AKAP interaction. Cell Motil Cytoskeleton 2008;65:539–552.
  • Wheatley DN, Feilen EM, Yin Z, Wheatley SP. Primary cilia in cultured mammalian cells: detection with an antibody against detyrosinated alpha-tubulin (ID5) and by electron microscopy. J Submicrosc Cytol Pathol 1994;26:91–102.
  • Wissam AAA, Shao TL, Surya MN. Primary cilia: highly sophisticated biological sensors. Sensors 2009;9(9):7003–7020.
  • Mahjoub MR. The importance of a single primary cilium. Organogenesis 2013;9:61–69.
  • McMahon AP, Ingham PW, Tabin CJ. Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol 2003;53:1–114.
  • Banizs B, Pike MM, Millican CL, Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus. Development 2005;132:5329–5339.
  • Park TJ, Haigo SL, Wallingford JB. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet 2006;38:303–311.
  • Nozawa YI, Lin C, Chuang PT. Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction. Curr Opin Genet Dev 2013;23:429–437.
  • Milenkovic L, Goodrich LV, Higgins KM, Scott MP. Mouse patched1 controls body size determination and limb patterning. Development 1999;126:4431–4440.
  • Huangfu D, Liu A, Rakeman AS, Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 2003;426:83–87.
  • Briscoe J, Therond PP. The mechanisms of Hedgehog signalling and its roles in development and disease. Nat Rev Mol Cell Biol 2013;14:416–429.
  • Tasouri E, Tucker KL. Primary cilia and organogenesis: is hedgehog the only sculptor? Cell Tissue Res 2011;345:21–40.
  • Grizzi F, Chiriva-Internati M, Franceschini B, Sperm protein 17 is expressed in human somatic ciliated epithelia. J Histochem Cytochem: official journal of the Histochemistry Society. 2004;52:549–554.
  • Barzi M, Berenguer J, Menendez A, Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base. J Cell Sci 2010;123:62–69.
  • Lea IA, Widgren EE, O'Rand MG. Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella. Reprod Biol Endocrinol 2004;2:57.
  • Newlon MG, Roy M, Morikis D, A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. The EMBO J 2001;20:1651–1662.
  • Mistry BV, Zhao Y, Chang TC, Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse. PLoS One 2013;8:2.
  • Behnam B, Modarressi MH, Conti V, Expression of Tsga10 sperm tail protein in embryogenesis and neural development: from cilium to cell division. Biochem Biophys Res Commun. United States 2006;344:1102–1110.
  • Karhadkar SS, Bova GS, Abdallah N, Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature 2004;431:707–712.
  • Athar M, Tang X, Lee JL, Hedgehog signalling in skin development and cancer. Exp Dermatol 2006;15:667–677.
  • Bhattacharya R, Kwon J, Ali B, Role of hedgehog signaling in ovarian cancer. Clin Cancer Res 2008;14:7659–7666.
  • Morris JP 4th, Wang SC, Hebrok M. KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nat Rev Cancer 2010;10:683–695.
  • Sanders BG, Kline K. Fetal-tumor membrane associated antigens: genetic and immunological implications. Trans Am Microsc Soc 1975;94:470–479.

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