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Original Article

Deviation of the Allergic IgE to an IgG Response by Gene Immunotherapy

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Pages 271-289 | Received 29 Aug 1997, Published online: 10 Jul 2009

References

  • Ulmer J. B., Donnelly J. J., Parker S. E., Rhodes G. H., Feigner P. L., Dwarki V. J., Gromkowsk S. H., Deck R. R., DeWitt C. M., Friedman A. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745–49
  • Fynan E. F., Webster R. G., Fuller D. H., Haynes J. R., Santoro J. C., Robinson H. L. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Nail. Acad. Sci. USA 1993; 90: 11478–82
  • Wang B., Ugen K. E., Srikantan V., Agadjanyan M. G., Dang K., Refaeli Y., Sato A. I., Boyer J., Williams W. V., Weiner D. B. Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 1993; 90: 4156–60
  • McDonnell W. M., Squires H. R, Jr. DNA vaccines. N. Eng. J. Med. 1996; 334: 42–45
  • Donnelly J. J., Ulmer J. B., Liu M. A. Immunization with DNA. J. Immunol. Meth. 1994; 176: 145–52
  • Raz E., Carson D. A., Parker S. E., Parr T. B., Abai A. M., Aichinger G., Gromkowski S. H., Singh M., Lew D., Yankauckas M. Y. Intradermal gene immunization: The possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl. Acad. Sci. USA 1994; 91: 9519–23
  • Cox G. J., Zamb T., Babiuk L. A. Bovine herpesvirus 1: Immune response in mice and in cattle injected with plasmid DNA. J. Virol 1993; 67: 5664–68
  • Xiang Z., Ertl H. C. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 1995; 2: 129–35
  • Davis H. L., McCluskie M. J., Gerin J. L., Purcell R. H. DNA vaccine for hepatitis B: Evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proc. Natl. Acad. Sci. USA 1996; 93: 7213–18
  • Hoffman S. L., Doolan D. L., Sedegah M., Gramzinski R., Wang H., Gowda K., Hobart K., Margalith M., Norman J., Hedstrom R. C. Nucleic acid malaria vaccines. Current status and potential. Ann. N.Y. Acad. Sci. 1995; 772: 88–94
  • Tascon R. E., Coiston M. J., Ragno S., Stavropoulos E., Gregory D., Lowrie D. B. Vaccination against tuberculosis by DNA injection. Nature Medicine 1996; 2: 888–92
  • Geissler M., Geisen A., Tokushige K., Wands J. R. Enhancement of cellular and humoral immune response to hepatitis C virus protein using DNA based vaccines augmented with cytokine expressing plasmids. J. Immunol. 1997; 158: 1231–37
  • Condon C., Watkins S. C., Celiuzi C M., Thompson K., Falo L. D, Jr. DNA based immunization by in vivo transfection of dendritic cells. Nature Medicine 1996; 2: 1122–28
  • Watanabe A., Raz E., Kohsaka H., Tighe H., Baird S. M., Kipps T. J., Carson D. A. Induction of antibodies to a kappa V region by gene immunization. J. Immunol. 1993; 151: 2871–76
  • Syrengelas A. D., Chen T. T., Levy R. DNA immunization induces protective immunity against B-cell lymphoma. Nature Medicine 1996; 1: 1038–41
  • Geissler E. K., Wang J., Fechner J. H., Jr., Burlingham W. J., Knechtle S. J. Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. J. Immunol. 1994; 152: 413–21
  • Waisman A., Ruiz P. J., Hirschberg D. L., Gelman A., Oksenberg J. R., Brocke S., Mor F., Cohen I. R., Steinman L. Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nature Medicine 1996; 2: 899–905
  • Raz E., Tighe H., Sato Y., Roman M., Corr M. P., Swain S. L., Spiegelberg H. L., Carson D. A. Preferential induction of Th1 response by intradermal gene vaccination. Proc. Natl. Acad. Sci. USA 1996; 93: 5141–45
  • Hsu C. H., Chua K. Y., Tao M. H., Lai Y. L., Wu H. D., Huang S. K., Hsieh K. H. Immunoprophylaxis of allergen induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nature Medicine 1996; 2: 540–44
  • Steinman R. M. The dendritic cell system and its role in immunogenicity. Ann. Rev. Immunol. 1991; 9: 271–96
  • Streilein J. W. Dermal cells: Underappreciated components of skin associated lymphoid tissues (SALT). The Dermal Immune System, B. J. Nickoloff. CRC Press, Boca Raton, FL 1993; 25–38
  • Aragane Y., Riemann H., Bhardwaj R. S., Schwarz A., Sawada Y., Yamada H., Luger T. A., Kubin M., Trinchieri G., Schwarz T. IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J. Immunol. 1994; 153: 5366–72
  • Corr M., Lee D. J., Carson D. A., Tighe H. Gene vaccination with naked plasmid DNA: Mechanism of CTL priming. J. Exp. Med. 1996; 184: 1555–60
  • Manickan E., Rouse R. J., Yu Z., Wire W. S., Rouse B. T. Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes. J. Immunol. 1995; 155: 259–65
  • Slater J. E., Zhang Y. J., Arthur-Smith A. A DNA vaccine inhibits IgE response to the latex allergen Hev b 5 in mice (abst.). J. Allergy Clin. Immunol. 1997; 99: S504
  • Lee D. J., Tighe H., Roman M., Carson D. A., Spiegelberg H. L., Raz E. Inhibition of IgE antibody formation by plasmid DNA immunization is mediated by both CD4+ and CD8+ T cells. Int. Arch. Allergy Immunol. 1997; 113: 227–30
  • Corry D. B., Folkesson H. G., Warnock M. L., Erie D. J., Matthay M. A., Wiener-Kronish J. P., Locksley R. M. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 1996; 183: 109–17
  • Broide D., Orozco E. M., Roman M., Carson D. A., Raz E. Intradermal gene vaccination down-regulate both arms of the allergic response (abst.). J. Allergy Clin. Immunol. 1997; 99: S129
  • Yamamoto S., Yamamoto T., Shimada S., Kuramoto E., Yano O., Kataoka T., Tokunaga T. DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth. Microbiol. Immunol 1992; 36: 983–97
  • Yamamoto T., Yamamoto S., Kataoka T., Komuro K., Kohase M., Tokunaga T. Synthetic oligonucleotides with certain palindromes stimulate interferon production of human peripheral blood lymphocytes in vitro. Japan J. Cancer Res. 1994; 85: 775–79
  • Messina J. P., Gilkeson G. S., Pisetsky D. S. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J. Immunol. 1991; 147: 1759–64
  • Pisetsky S. D. The immunologic properties of DNA. J. Immunol. 1996; 156: 421–23
  • Pisetsky S. D. DNA and the immune system. Ann. Int Med. 1997; 126: 169–71
  • Krieg A. M., Yi A. K., Matson S., Waldschmidt T. J., Bishop G. A., Teasdale R., Koretzky G. A., Klinman D. M. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374: 546–49
  • Klinman D. M., Yi A. K., Beaucage S. L., Conove J., Krieg A. M. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc. Natl. Acad. Sci. USA 1996; 93: 2879–83
  • Cowdery J. S., Chace J. H., Yi A. K., Krieg A. M. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J. Immunol. 1996; 156: 4570–75
  • Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M. D., Silverman G. J., Lotz M., Carson D. A., Raz E. Immunostimulatory DNA sequences necessary for effective intradennal gene immunization. Science 1996; 273: 352–54
  • Roman M., Martin-Orozco E., Goodman J., Nguyen M. D., Sato Y., Ronaghy A., Kornbluth R. S., Richman D. D., Carson D. A., Raz E. Immunostimulatory DNA sequences function as Th1 inducing adjuvants. Nature Medicine 1997; 3: 849–54
  • Brinkmann V., Geiger T., Alkan S., Heusser C. H. Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells. J. Exp. Med. 1993; 178: 1655–63
  • Yaegashi Y., Nielsen P., Sing A., Galanos C., Freudenberg M. A. Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice. J. Exp. Med. 1995; 181: 953–60
  • Trinchieri G. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Ann. Rev. Immunol. 1995; 13: 251–76
  • Okamura H., Tsutsi H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 1995; 378: 88–91
  • Freund J., Casals J., Hosmer E. P. Sensitization and antibody formation after injection of tubercle bacilli and parafin oil. Proc. Soc. Exp. Biol. Med. 1937; 37: 509–13
  • Kimura Y., Sonehara K., Kuramoto E., Makino T., Yamamoto S., Yamamoto T., Kataoka T., Tokunaga T. Binding of oligoguanylate to scavenger receptors is required for oligonucleotides to augment NK cell activity and induce IFN. J. Biochem. 1994; 116: 991–94
  • Raz E., Carson D. A., Rhodes G., Abai A. M., Tsai Y. J., Wheeler C J., Feigner P., Baird S. M. Cationic lipids inhibit intradermal genetic vaccination. Vaccine 1994; 94: 71–75
  • Raz E., Roman M., Orozco E. M., Carson E. M. Immunostimulatory (ISS) sequences are a Th1 promoting adjuvant (abst). J. Allergy Clin. Immunol. 1997; 99: S365
  • Bradley L. M., Dalton O. K., Croft M. A. Direct role for IFN-gamma in regulation of Th1 cell development. J. Immunol. 1996; 157: 1350–58
  • Broide D., Schwartz J., Tighe H., Gifford T., Nguyen M. D., Malek S., VanUden J., Martin-Orozco E., Gelfand E. W., Raz E. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 1998; 161: 7054–62
  • Horner A. A., Ronaghy A., Cheng P. M., Nguygen M. D., Cho H. J., Broide D., Raz E. Immunostimulatory DNA is a potent mucosal adjuvant. Cell. Immunol. 1998; 190: 77–82

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