Intra-renal and urinary mRNA expression of podocyte-associated molecules for the estimation of glomerular podocyte loss

REFERENCES

• Cooper L. USRDS annual data report. Nephrol News Issues. 2001;15:31–38.
   Google Scholar
• Dagogo-Jack S. Primary prevention of type-2 diabetes in developing countries. J Natl Med Assoc. 2006;98:415–419.
   PubMed Web of Science ®Google Scholar
• Marshall SM. The podocyte: A major player in the development of diabetic nephropathy? Horm Metab Res. 2005;37:9–16.
   PubMedGoogle Scholar
• White KE, Bilous RW, Diabiopsies study G. Structural alterations to the podocyte are related to proteinuria in type 2 diabetic patients. Nephrol Dial Transplant. 2004;19:1437–1440.
   PubMed Web of Science ®Google Scholar
• White KE, Bilous RW, Marshall SM, Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes. 2002;51:3083–3089.
   PubMed Web of Science ®Google Scholar
• Macconi D, Bonomelli M, Benigni A, Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury. Am J Pathol. 2006;168:42–54.
   PubMed Web of Science ®Google Scholar
• Kriz W, Lemley KV. The role of the podocyte in glomerulosclerosis. Curr Opin Nephrol Hypertens. 1999;8:489–497.
   PubMedGoogle Scholar
• Pagtalunan ME, Miller PL, Jumping-Eagle S, Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest. 1997;99:342–348.
   PubMed Web of Science ®Google Scholar
• Shirato I, Hishiki T, Tomino Y. Podocyte loss and progression of diabetic nephropathy. Contrib Nephrol. 2001;134:69–73.
   Google Scholar
• Dalla Vestra M, Masiero A, Roiter AM, Saller A, Crepaldi G, Fioretto P. Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes. Diabetes. 2003;52:1031–1035.
   PubMed Web of Science ®Google Scholar
• Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol. 2002;13:3005–3015.
   PubMed Web of Science ®Google Scholar
• Petermann AT, Pippin J, Krofft R, Viable podocytes detach in experimental diabetic nephropathy: Potential mechanism underlying glomerulosclerosis. Nephron Exp Nephrol. 2004;98:e114–e123.
   PubMedGoogle Scholar
• Petermann AT, Krofft R, Blonski M, Podocytes that detach in experimental membranous nephropathy are viable [see comment]. Kidney Int. 2003;64:1222–1231.
   PubMed Web of Science ®Google Scholar
• Vogelmann SU, Nelson WJ, Myers BD, Lemley KV. Urinary excretion of viable podocytes in health and renal disease. Am J Physiol Renal Physiol. 2003;285:F40–F48.
   PubMed Web of Science ®Google Scholar
• Camici M. Urinary detection of podocyte injury. Biomed Pharmacother. 2007;61:245–249.
   PubMed Web of Science ®Google Scholar
• Hara M, Yanagihara T, Itoh M, Matsuno M, Kihara I. Immunohistochemical and urinary markers of podocyte injury. Pediatr Nephrol. 1998;12:43–48.
   Google Scholar
• Patari A, Forsblom C, Havana M, Taipale H, Groop PH, Holthofer H. Nephrinuria in diabetic nephropathy of type 1 diabetes. Diabetes. 2003;52:2969–2974.
   PubMed Web of Science ®Google Scholar
• Yu D, Petermann A, Kunter U, Rong S, Shankland SJ, Floege J. Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol. 2005;16:1733–1741.
   PubMed Web of Science ®Google Scholar
• Wang G, Lai F-M, Lai K-B, Chow K-M, Li K-TP, Szeto C-C. Messenger RNA expression of podocyte-associated molecules in the urinary sediment of patients with diabetic nephropathy. Nephron Clin Pract. 2007;106:c169–c179.
   PubMedGoogle Scholar
• Szeto CC, Lai KB, Chow KM, Messenger RNA expression of glomerular podocyte markers in the urinary sediment of acquired proteinuric diseases. Clin Chim Acta. 2005;361:182–190.
   PubMed Web of Science ®Google Scholar
• Wirta O, Helin H, Mustonen J, Kuittinen E, Savela T, Pasternack A. Renal findings and glomerular pathology in diabetic subjects. Nephron. 2000;84:236–242.
   Google Scholar
• Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group [see comment]. Ann Intern Med. 1999;130:461–470.
   PubMed Web of Science ®Google Scholar
• Weibel ER. Stereological Methods. Practical Methods for Biological Morphometry. Vol 1. London: Academic Press, Inc; 1979:40–116.
   Google Scholar
• Barisoni L, Kriz W, Mundel P, D'Agati V. The dysregulated podocyte phenotype: A novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol. 1999;10:51–61.
   PubMed Web of Science ®Google Scholar
• Najafian B, Basgen JM, Mauer M. Estimating mean glomerular volume using two arbitrary parallel sections. J Am Soc Nephrol. 2002;13:2697–2705.
   Google Scholar
• Bruneval P, Bariety J, Belair MF, Mandet C, Heudes D, Nicoletti A. Mesangial expansion associated with glomerular endothelial cell activation and macrophage recruitment is developing in hyperlipidaemic apoE null mice. Nephrol Dial Transplant. 2002;17:2099–2107.
   PubMed Web of Science ®Google Scholar
• Li B, Hartono C, Ding R, Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med. 2001;344:947–954.
   PubMed Web of Science ®Google Scholar
• Szeto CC, Chan RW, Lai KB, Messenger RNA expression of target genes in the urinary sediment of patients with chronic kidney diseases. Nephrol Dial Transplant. 2005;20:105–113.
   PubMed Web of Science ®Google Scholar
• Biosystems FCCA. Guide to Performing Relative Quantitation of Gene Expression Using Real-Time Quantitative PCR. 2004.
   Google Scholar
• Biosystems FCCA. Amplification Efficiency of TaqMan® Gene Expression Assays. 2006.
   Google Scholar
• Basgen JM, Nicholas SB, Mauer M, Rozen S. Nyengaard JR. Comparison of methods for counting cells in the mouse glomerulus. Nephron Exp Nephrol. 2006;103:e139–e148.
   Google Scholar
• White KE, Bilous RW. Estimation of podocyte number: A comparison of methods. Kidney Int. 2004;66:663–667.
   Google Scholar
• Siu B, Saha J, Smoyer WE, Sullivan KA, Brosius FC3rd. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: Prevention by lipoic acid treatment. BMC Nephrol. 2006;7:6.
   PubMedGoogle Scholar
• Sanden SK, Wiggins JE, Goyal M, Riggs LK, Wiggins RC. Evaluation of a thick and thin section method for estimation of podocyte number, glomerular volume, and glomerular volume per podocyte in rat kidney with Wilms’ Tumor-1 protein used as a podocyte nuclear marker. J Am Soc Nephrol. 2003;14:2484–2493.
   PubMed Web of Science ®Google Scholar
• Langham RG, Kelly DJ, Cox AJ, Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: Effects of angiotensin converting enzyme inhibition. Diabetologia. 2002;45:1572–1576.
   PubMed Web of Science ®Google Scholar
• Susztak K, Raff AC, Schiffer M, Böttinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes. 2006;55:225–233.
   PubMed Web of Science ®Google Scholar
• Kretzler M. Role of podocytes in focal sclerosis: Defining the point of no return [comment]. J Am Soc Nephrol. 2005;16:2830–2832.
   Google Scholar