PAX2 re-expression in renal tubular epithelial cells and correlation with renal interstitial fibrosis of rats with obstructive nephropathy

REFERENCES

• Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med. 2004;82(3):175–181.
   PubMed Web of Science ®Google Scholar
• Liu Y. Renal fibrosis: New insights into the pathogenesis and therapeutics. Kidney Int. 2006;69(2):213–217.
   PubMed Web of Science ®Google Scholar
• Bascands JL, Schanstra JP. Obstructive nephropathy: Insights from genetically engineered animals. Kidney Int. 2005 Sep;68(3):925–937.
   PubMed Web of Science ®Google Scholar
• Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M. PAX2 and Pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007;18(4):1121–1129.
   PubMed Web of Science ®Google Scholar
• Geng WM, Yi ZW, He XJ, Function of PAX2 in tubular epithelium transdifferentiation. J Clin Pediatr. 2007;25(4): 284–287.
   Google Scholar
• Cohen T, Loutochin O, Amin M, Capolicchio JP, Goodyer P, Jednak R. PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death. Am J Physiol Renal Physiol. 2007;292(4): F1267–F1273.
   Web of Science ®Google Scholar
• Taal MW, Zandi-Nejad K, Weening B, Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney. Kidney Int. 2000;58(4):1664–1676.
   PubMed Web of Science ®Google Scholar
• Mizuguchi Y, Miyajima A, Kosaka T, Asano T, Asano T, Hayakawa M. Atorvastatin ameliorates renal tissue damage in unilateral ureteral obstruction. J Urol. 2004;172(6 Pt 1):2456–2459.
   PubMed Web of Science ®Google Scholar
• Chen F. Genetic and developmental basis for urinary tract obstruction. Pediatr Nephrol. 2009;24(9):1621–1632.
   PubMed Web of Science ®Google Scholar
• Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M. Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol. 2008;130(1):141–155.
   PubMed Web of Science ®Google Scholar
• Kaneto H, Morrissey J, McCracken R, Reyes A, Klahr S. Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int. 1994; 45(6):1637–1647.
   PubMed Web of Science ®Google Scholar
• Rothenpieler UW, Dressler GR. Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development. Development. 1993;119(3):711–720.
   PubMed Web of Science ®Google Scholar
• Eccles MR, Wallis LJ, Fidler AE, Spurr NK, Goodfellow PJ, Reeve AE. Expression of the PAX2 gene in human fetal kidney and Wilms' tumor. Cell Growth Differ. 1992;3(5): 279–289.
   PubMedGoogle Scholar
• Grote D, Souabni A, Busslinger M, Bouchard M. Pax-2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development. 2006;133(1):53–61.
   PubMed Web of Science ®Google Scholar
• Torban E, Dziarmaga A, Iglesias D, PAX2 activates WNT4 expression during mammalian kidney development. J Biol Chem. 2006;281(18):12705–1212.
   PubMed Web of Science ®Google Scholar
• Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol. 2004;15(1):1–12.
   PubMed Web of Science ®Google Scholar
• Fukuzawa R, Eccles M, Ikeda M, Hata J. Embryonal hyperplasia of Bowman's capsular epithelium in patients with WT1 mutations. Pediatr Nephrol. 2003;18(1):9–13.
   PubMed Web of Science ®Google Scholar
• Letavernier E, Bruneval P, Mandet C, High sirolimus levels may induce focal segmental glomerulosclerosis de novo. Clin J Am Soc Nephrol. 2007;2(2):326–333.
   PubMed Web of Science ®Google Scholar
• Ohtaka A, Ootaka T, Sato H, Ito S. Phenotypic change of glomerular podocytes in primary focal segmental glomerlosclerosis: Developmental paradigm? Nephrol Dial Transplant. 2002;17(Suppl. 9):11–15.
   PubMedGoogle Scholar
• Wagner KD, Wagner N, Guo JK, An inducible mouse model for PAX2-dependent glomerular disease: Insights into a complex pathogenesis. Curr Biol. 2006;16(8):793–800.
   PubMed Web of Science ®Google Scholar
• Zhang HQ, Yi ZW, He XJ, Dang XQ, He QN, Mo SH. PAX2 expression in children with steroid-resistant primary nephrotic syndrome. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005;30(5):597–600.
   PubMedGoogle Scholar
• E1-Nahas AM. Plasticity of kidney cells: Role in kidney remodeling and scarring. Kidney Int. 2003;64(5):1553–1563.
   PubMed Web of Science ®Google Scholar
• Chevalier RL. Chronic partial ureteral obstruction and the developing kidney. Pediatr Radiol. 2008;38(Suppl. 1):S35–S40.
   Google Scholar
• Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol. 2008;214(2):199–210.
   PubMed Web of Science ®Google Scholar
• Li MX, Liu BC. Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis. Chin Med J (Engl). 2007;120(21):1925–1930.
   PubMed Web of Science ®Google Scholar
• Burns WC, Kantharidis P, Thomas MC. The role of tubular epithelial–mesenchymal transition in progressive kidney disease. Cells Tissues Organs. 2007;185(1–3):222–231.
   PubMed Web of Science ®Google Scholar
• Rastaldi MP. Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis. J Nephrol. 2006;19(4):407–412.
   PubMed Web of Science ®Google Scholar