Aluminum Exacerbates Cyclosporin Induced Nephrotoxicity in Rats

References

• Wish J B. Immunologic effects of cyclosporin. TransplantProc 1987; 7(suppl 2)15–18
   Google Scholar
• Buurman W A, Ruers T JM, Daemen I A, et al. Cyclosporin A inhibits IL-2 driven proliferation of human alloactivated T-cells. J Immunol 1987; 136: 4035–4039
   Google Scholar
• Borel J F. Cyclosporin: Historical perspectives. Transplant Proc 1983; 15(suppl 1)2219–2229
   Google Scholar
• Berg K J, Forre O, Bjerkhoel F, et al. Side effects of cyclosporin A treatment in patients with rheumatoid arthritis. Kidney Int 1986; 29: 1180–1187
   PubMed Web of Science ®Google Scholar
• Bueding E, Hawkins J, Chu J W. Antischistosomal effects of cyclosporin A. Agents Actions 1981; 11: 380–383
   PubMedGoogle Scholar
• Thommen-Scott K. Antimalarial adivity of cylorporin A. Agents Actions 1981; 11: 770–773
   Google Scholar
• Calne R Y, White D JG, Thiru S, et al. Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet 1978; 2: 1323–1327
   PubMed Web of Science ®Google Scholar
• Mihatsch M J, Ryffel B, Gudat F, Thiel G. Cyclosporin nephropathy. Renal Pathology, with Clinical and Functional Correlations, 2nd Edn, C G Tischer, B M Brenner. Lippincolt, Philadelphia, PA 1994
   Google Scholar
• Termeer A, Hoitsnia A J, Koene R AP. Severe nephrotoxicity caused by the combined use of gentamicin and cyclosporin in renal allograft recipients. Transplantation 1986; 42: 220–221
   PubMed Web of Science ®Google Scholar
• Whiting P H, Burke M D, Thomson A W. Drug interactions with cyclosporin: Implications from animal studies. Transplant Proc 1986; 18(suppl 5)56–70
   PubMed Web of Science ®Google Scholar
• Cockburn I. Cyclosporin A: Clinical evaluation of drug interactions. Transplant Proc 1986; 18(suppl 5)50–55
   Google Scholar
• Dieperink H, Kemp E, Leyssac P P, et al. Ketoconazole and cyclosporin A: Combined effects on rat renal function and on serum and tissue cyclosporin A concentration. Clin Nephrol 1986; 25(suppl 1)S137–S143
   Google Scholar
• Lione A. Aluminum in food. NutrRev 1984; 42: 31
   Google Scholar
• Trapp J A, Cannon J B. Aluminum pots as a source of dietary aluminum. N Engl J Med 1981; 304: 172
   PubMedGoogle Scholar
• Levick S E. Dementia from aluminum pots. N Engl J Med 1980; 303: 164
   Google Scholar
• Jackson M C, Huang P M. Aluminum of acid soils in the food chain and senelity. Sci Total Environ 1983; 28: 269–276
   PubMed Web of Science ®Google Scholar
• Kovalchik M T, Kaehny W D, Hegg A P, Jackson J T, Alfrey A C. Aluminum kinetics during hemodialysis. J Lab Clin Med 1978; 92: 712–720
   PubMed Web of Science ®Google Scholar
• Mayor G H, Keiser J A, Makdani D, Ku P K. Aluminum absorption and distribution: effect of parathyroid hormone. Science 1977; 197: 1187–1189
   PubMed Web of Science ®Google Scholar
• Attman P. Aluminum toxicity in dialysis patients: no evidence for a threshold serum aluminum concentration. Nephrol Dial Tranplant 1993, suppl 1: 25–34
   Google Scholar
• Friga V, Linos A, Linos D A. Is aluminum toxicity responsible for uremic puritis in chronic hemodialysis patients?. Nephron 1997; 75: 48–53
   Google Scholar
• Buege J A, Aust S D. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302–310
   PubMedGoogle Scholar
• Drapper H H, Squires E J, Mahmoodi H, Wu J, Agarwal S, Hadley M. A comparative evaluation of thiobarbituric acid mahods for the determination of malondialdehyde in biological materials. Free Radic Biol Med 1993; 15: 353–363
   Google Scholar
• English J, Evan A, Houghton D C, Bennett W M. Cyclosporin induced acute renal dysfunction in the rat. Evidence of arteriolar vasoconstriction with preservation of tubular function. Transplantation 1987; 44: 135–141
   PubMed Web of Science ®Google Scholar
• Blair J T, Thomson A W, Whiting P H, Davidson R. JL, Simpson J G. Toxicity of the immune suppressant cyclosporin A in the rat. J Pathol 1982; 138: 163–178
   PubMed Web of Science ®Google Scholar
• Ryffel B, Mihatsch M J. Cyclosporin nephrotoxicity. Toxicol Pathol 1986; 14: 73–82
   PubMedGoogle Scholar
• Mason J. The pathophysiology of sandimmune (cyclosporin) in man and animals. Pediatr Nephrol 1990; 4: 554–574
   PubMed Web of Science ®Google Scholar
• White D J, Thimmerman W, Davies H S, Nagao T, Kasahara K, Plumb A. Properties of cyclosporin A induced graft acceptance. Transplant Proc 1981; 13: 379–382
   Google Scholar
• Bertani I, Perico N, Abbate M, Battaglia C, Remuzzi G. Renal injury induced by long-term administration of cyclosporin A to rats. Am J Pathol 1987; 127: 569–579
   PubMed Web of Science ®Google Scholar
• Mihatsch M J, Ryffel B, Hermle M, Brunner F P, Thiel G. Morphology of cyclosporin nephrotoxicity in the rat. Clin Nephrol 1986; 25(suppl 1)S2–S8
   Google Scholar
• Fulton B, Jeffrey E H. The temporal relationship between hepatic GSH loss, heme oxygenase induction and cythrome P450 loss following intraperitoneal aluminum administration to mice. Toxicol Appl Pharmacol 1994; 127: 291–297
   PubMed Web of Science ®Google Scholar
• Bidlack W R, Brown R C, Meskin M S, Lee T C, Klein G L. Effect of aluminum on the hepatic mixed fundion oxidase and drug metabolism. Drug-Nutr Interact 1987; 5: 33–42
   PubMedGoogle Scholar
• Jeffrey E H, Jansen H T, Dellinger J A. In vivo interadion of aluminum with hepatic cytochrome 450 and metallothionein. Fundam Appl Toxicol 1987; 8: 541–548
   Google Scholar
• Cunningham C, Whiting P H, Burke M D, Wheatley D N, Simpson J G. Increasing the hepatic metabolism of cyclosporin abolishes nephrotoxicity. Transplant Proc 1983; 25: 2712–2715
   Google Scholar
• Whiting P H, Thomson A W, Simpson J G. Cyclosporin Toxicity, metabolism and drug interaction. Implications from animal studies. Tronsplant Proc 1985; 17(suppl 1)134–144
   Google Scholar
• Freeman D J, Luapacis A, Keown P A, Stiller C R, Carruthers S G. Evaluations of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites. Br J Clin Pharmacol 1984; 18: 887–893
   PubMed Web of Science ®Google Scholar
• Hopps V, Galione A, Biondi F, Vaccaro F, Sorrentio M C, Verti P, Leone F. Rifampicin reduces nephrotoxicity of cyclosporin A in rats: Studies on renal enzyne excretion. Transplant Proc 1988; 20(suppl 2)557–560
   Google Scholar
• Walker R J, Lazzaro V A, Duggin G G, Horvath J S, Tiller D J. Evidence that alterations in renal metabolism and lipid peroxidation may contribute to cyclosporin nephrotoxicity. Transplantation 1990; 50: 487–492
   PubMed Web of Science ®Google Scholar
• Suleymanlar G, Suleymanlar T, Shapiro J I, Chan L. Possible role of lipid peroxidation in cyclosporin nephrotoxialy in rats. Tranplant Proc 1994; 26: 2888–2889
   PubMed Web of Science ®Google Scholar
• Wang C, Salahudeen A K, McClain M, Whitehead J. Lipid peroxidation accompanies cyclosporin nephrotoxicity: Effects of vitamin E. Kidney Int 1995; 47: 927–934
   PubMed Web of Science ®Google Scholar
• De Lema G P, Arribas-Gomez I, Ruiz-Gines J A, et al. Reactive oxygen species mediate the effects of cyclosporin A on human cultured mesangial cells. Transplant Proc 1997; 29: 1241–1243
   Google Scholar
• Chainy G BN, Sahoo A, Swain C. Effect of aluminum on lipid peroxidation of cerebral hemisphere of chick. Bull Environ Contam Toxicol 1993; 50: 85–91
   Google Scholar
• Anderson R, Van Rensburg C EJ, Myer M S. α-Tocopherol prevents cyclosporin A-mediated activation of phospholipase A2 and inhibition of Na+, K+-Adenosine Triphosphatase activity in cultured hamster renal tubular cells. Toxicol Appl Pharmacol 1994; 125: 176–183
   PubMedGoogle Scholar
• Lin L L, Lin A Y, Knopf J L. Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid. Proc Natl Acad Sci USA 1992; 89: 6147–6151
   PubMed Web of Science ®Google Scholar
• Teraoka S, Takahashi K, Tanabe K, et al. Improvement in renal blood flow and kidney function by modulation of prostaglandin metabolism m cyclosporin treated animals. Transplant Proc 1989; 21: 937–940
   Google Scholar
• Voss B L, Hamilton K K, Samara E NS, McKee P A. Cyclosporin suppression of endothelial prostacyclin generation. Transplantation 1988; 45: 793–796
   PubMed Web of Science ®Google Scholar
• Churchill P C, Rossi N F, Ellis V R, Churchill M C, McDonald F D. Cyclosporin A inhibits prostaglandin E2 release and has no effect on renin secretion from renal cortical slices. Life Sci 1990; 47: 1579–1586
   Google Scholar
• Smeesters C, Chaland P, Giroux L, et al. Prevention of acute cyclosporin A nephrotoxicity by a thromboxane synthetase inhibitor. Tranplant Proc 1988; 20(suppl 2)663–669
   Google Scholar
• Petric R, Freeman D, Wallace C, McDonald J, Stiller C, Keown P. Modulation of experimental cyclosporin nephrotoxicity by inhibition of thromboxane synthesis. Transplantation 1990; 50: 558–563
   Google Scholar
• Perico N, Bosco E, Rossini M, et al. Acute cyclosporin A nephrotoxicity in rats: which role for reninangiotensin system and glomerular prostaglandin?. Clin Nephrol 1986; 25: S83–S88
   Google Scholar
• Lee D BN. Cyclosporin andthemin-angiotemm axis. Kidney Int 1997; 52: 248–260
   Google Scholar
• Mason J, Muller-Schweinitzer E, Dupont M, et al. Cyclosporin and the renin-angiotensin system. Kidney Int 1991; 39(suppl 32)S28–S32
   Google Scholar
• Fuse I, Taie H. Stimulations of arachidonate release and inositol-1,4,5-triphosphate formation are mediated by distinct G-proteins in human platelets. Biochem Biophys Res Comm 1987; 146: 659–665
   Google Scholar
• Chugh S N, Singhal H R, Mehta L, Chugh K, Shankar V, Malhotra K C. Plasma renin activity in shock due to aluminum phosphide poisoning. J Assoc Physcians India 1990; 38: 398–399
   PubMedGoogle Scholar
• Suleymanlar G, Suleymanlar I, Shapiro J, Chan L. Efficacy of vaapamil m prevention of cyclosporin nephrotoxicity m the rat. Transplant Proc 1994; 26: 2896–2898
   Google Scholar
• Ruggenenti P, Perico N, Mosconi L, et al. Calcium channel blockers protect transplant patients & om cyclosporin-induced daily renal hypoperfusion. Kidney Int 1993; 43: 706–711
   PubMed Web of Science ®Google Scholar
• Julka D, Gill K D. Altered calcium homeostasis: a possible mechanism of aluminum-induced neurotoxicity. Biochim Biophys Acta 1996; 1315: 47–54
   PubMed Web of Science ®Google Scholar
• Trapp G A. Interaction of aluminum with cofactors, enzymes and other proteins. Kidney Int 1986; 29: S12–S16
   Google Scholar
• Prabhu S D, Salama G. The heavy metal ions Ag+ and Hg2+ trigger calcium release from cardiac sarcoplasmic reticulum. Arch Biochem Biophys 1990; 277: 47–55
   PubMed Web of Science ®Google Scholar
• Babizhayev M A. The biphasic effect of calcium on lipid peroxidation. Arch Biochem Biophys 1988; 266: 445–451
   Google Scholar