1,213
Views
64
CrossRef citations to date
0
Altmetric
Laboratory Studies

Repeated administration of bone marrow-derived mesenchymal stem cells improved the protective effects on a remnant kidney model

, , , , , , , , & show all
Pages 840-848 | Received 12 Feb 2010, Accepted 11 May 2010, Published online: 21 Jul 2010

REFERENCES

  • Pittenger MF, Mackay AM, Beck SC, Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143–147.
  • Dominici M, Le Blank K, Mueller I, Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315–317.
  • Morigi M, Introna M, Imberti B, Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells. 2008;26:2075–2082.
  • Qian H, Yang H, Xu W, Bone marrow mesenchymal stem cells ameliorate rat acute renal failure by differentiation into renal tubular epithelial-like cells. Int J Mol Med. 2008;22:325–332.
  • Choi S, Park M, Kim J, Hwang S, Park S, Lee Y. The role of mesenchymal stem cells in the functional improvement of chronic renal failure. Stem Cells Dev. 2009;18:521–529.
  • Morigi M, Imberti B, Zoja C, Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol. 2004;15:1759–1804.
  • Tögel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol. 2005;289:F31–F42.
  • Ninichuk V, Gross O, Segerer S, Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Kidney Int. 2007;70:121–129.
  • Alexandre CS, Volpini RA, Shimizu MH, Lineage-negative bone marrow cells protect against chronic renal failure. Stem Cells. 2009;27:682–692.
  • Herrera MB, Bussolati B, Bruno S, Fonsato V, Romanazzi GM, Camussi G. Mesenchymal stem cells contribute to the renal repair of acute tubular epithelial injury. Int J Mol Med. 2004;14:1035–1041.
  • Striker GE, Mannik M, Tung MY. Role of marrow-derived monocytes and mesangial cells in removal of immune complexes from renal glomeruli. J Exp Med. 1979;149:127–136.
  • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005;105:1815–1822.
  • Inoue S, Popp FC, Koehl GE, Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant model. Transplantation. 2006;81:1589–1595.
  • Striker GE, Striker LJ. Glomerular cell culture. Lab Invest. 1986;53:181–191.
  • Podjarny E, Bernheim J, Hasdan G, Additive renoprotective effect of candesartan and tetrahydrobiopterin in rats after 5/6 nephrectomy. Nephrol Dial Transplant. 2007;22:1864–1872.
  • Fujihara CK, Antunes GR, Mattar AL, Malheiros DM, Vieira JM Jr, Zatz R. Chronic inhibition of nuclear factor-kappa B attenuates renal injury in the 5/6 renal ablation model. Am J Physiol Renal Physiol. 2006;292:F92–F99.
  • Jeong KH, Lee TW, Ihm CG, Lee SH, Moon JY, Lim SJ. Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats. Am J Nephrol. 2009;29:274–282.
  • Rossi P, Dolci S, Albanesi C, Grimaldi P, Geremia R. Direct evidence that the mouse sex-determining gene Sry is expressed in the somatic cells of male fetal gonads and in the germ cell line in the adult testis. Mol Reprod Dev. 1993;34:369–373.
  • Caldas HC, Fernandes IM, Gerbi F, Effect of whole bone marrow cell infusion in the progression of experimental chronic renal failure. Transplant Proc. 2008;40:853–855.
  • Hishikawa K, Fujita T. Stem cells and kidney disease. Hypertens Res. 2006;29:745–749.
  • Kunter U, Rong S, Djuric Z, Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. J Am Soc Nephrol. 2006;17:2202–2212.
  • Ostendorf T, Kunter U, Eitner F, VEGF-β mediates glomerular endothelial repair. J Clin Invest. 1999;104:913–923.
  • Schrijvers BF, Flyvbjerg A, Tilton RG, Rasch R, Lameire NH, De Vriese AS. Pathophysiological role of vascular endothelial growth factor in the remnant kidney. Nephron Exp Nephrol. 2005;101:e9–e15.
  • Coimbra TM, Carvalho J, Fattori A, Da Silva CG, Lachat JJ. Transforming growth factor-beta production during the development of renal fibrosis in rats with subtotal renal ablation. Int J Exp Pathol. 1996;77:167–173.
  • Hamar P, Peti-Peterdi J, Rázga Z, Kovács G, Heemann U, Rosivall L. Coinhibition of immune and renin-angiotensin systems reduces the pace of glomerulosclerosis in the rat remnant kidney. J Am Soc Nephrol. 1999;10:S234–S238.
  • Choi JJ, Yoo SA, Park SJ, Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice. Clin Exp Immunol. 2008;153:269–276.
  • Du YY, Zhou SH, Zhou T, Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction. Cytotherapy. 2008;10:469–478.
  • Crop MJ, Baan CC, Korevaar SS, Donor-derived mesenchymal stem cells suppress alloreactivity of kidney transplant patients. Transplantation. 2009;87:896–906.
  • Cavaglieri RC, Martini D, Sogayar MC, Noronha IL. Mesenchymal stem cells delivered at the subcapsule of the kidney ameliorate renal disease in the rat remnant kidney model. Transplant Proc. 2009;41:947–951.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.