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Laboratory Studies

Exercise-induced changes in renal URAT1 activity and expression in rats

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Pages 855-862 | Received 09 Mar 2010, Accepted 11 May 2010, Published online: 21 Jul 2010

REFERENCES

  • Oner G, Cirrik S. The nephrotoxicity risk in rats subjected to heavy muscle activity. J Sport Sci Med. 2009;8:481–488.
  • Cirrik S, Oner G. The effect of heavy muscle activity on renal cytoresistance in rats. Ren Fail. 2009;31:683–689.
  • Poortmans JR. Exercise and renal function. Sports Med. 1984;1:125–153.
  • Poortmans JR, Vanderstraeten J. Kidney function during exercise in healthy and diseased humans. An update. Sports Med. 1994;18:419–437.
  • Mittleman KD, Zambraski EJ. Exercise-induced proteinuria is attenuated by indomethacin. Med Sci Sports Exerc. 1992;24:1069–1074.
  • Poortmans JR, Vancalck B. Renal glomerular and tubular impairment during strenuous exercise in young women. Eur J Clin Invest. 1978;8:175–178.
  • Poortmans JR, Mathieu N, De Plaen P. Influence of running different distances on renal glomerular and tubular impairment in humans. Eur J Appl Physiol Occup Physiol. 1996;72: 522–527.
  • Balsom PD, Seger JY, Sjödin B, Ekblom B. Physiological responses to maximal intensity intermittent exercise. Eur J Appl Physiol Occup Physiol. 1992;65:144–149.
  • Stathis CG, Febbraio MA, Carey MF, Snow RJ. Influence of sprint training on human skeletal muscle purine nucleotide metabolism. J Appl Physiol. 1994;76:1802–1809.
  • Tullson PC, Bangsbo J, Hellsten Y, Richter EZ. IMP metabolism in human skeletal muscle after exhaustive exercise. J Appl Physiol. 1995;78:146–152.
  • Hediger MA, Johnson RJ, Miyazaki H, Endou H. Molecular physiology of urate transport. Physiology (Bethesda). 2005;20:125–133.
  • Capasso G, Jaeger P, Robertson WG, Unwin RJ. Uric acid and the kidney: Urate transport, stone disease and progressive renal failure. Curr Pharm. 2005;11:4153–4159.
  • Enomoto A, Endou H. Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease. Clin Exp Nephrol. 2005;9:195–205.
  • Gündüz F, Sentürk UK. The effect of reactive oxidant generation in acute exercise-induced proteinuria in trained and untrained rats. Eur J Appl Physiol. 2003;90(5–6):526–532.
  • Ji LL, Leichtweis S. Exercise and oxidative stress: Sources of free radicals and their impact on antioxidant systems. Age. 1997;20:91–106.
  • Banerjee AK, Mandal A, Chanda D, Chakraborti S. Oxidant, antioxidant and physical exercise. Mol Cell Biochem. 2003;253(1–2):307–312.
  • Choi HK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med. 2005;143:499–516.
  • Mazzali M, Hughes J, Kim YG, Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension. 2001;38:1101–1106.
  • Menè P, Punzo G. Uric acid: Bystander or culprit in hypertension and progressive renal disease? J Hypertens. 2008;26:2085–2092.
  • Koch M, De Keyser J. Uric acid in multiple sclerosis. Neurol Res. 2006;28:316–319.
  • Weisskopf MG, O'Reilly E, Chen H, Schwarzschild MA, Ascherio A. Plasma urate and risk of Parkinson's disease. Am J Epidemiol. 2007;166:561–567.
  • Hooper DC, Spitsin S, Kean RB, Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci U S A. 1998;95:675–680.
  • Kahn AM. Indirect coupling between sodium and urate transport in the proximal tubule. Kidney Int. 1989;36(3):378–384.
  • Reem GH, Vanamee P. Effect of sodium lactate on urate clearance in the dalmatian and in the mongrel. Am J Physiol. 1964;207:113–117.
  • Enomoto A, Kimura H, Chairoungdua A, Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature. 2002;417:447–452.
  • Rizwan AN, Burckhardt G. Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, physiological, and pathological roles. Pharm Res. 2007;24:450–470.
  • Sperling O. Hereditary renal hypouricemia. Mol Genet Metab. 2006;89:14–18.
  • Ohno M, Ka T, Inokuchi T, Effects of exercise and grape juice ingestion in combination on plasma concentrations of purine bases and uridine. Clin Chim Acta. 2008;388:167–172.
  • Nguyen MT, Awale S, Tezuka Y, Hypouricemic effects of acacetin and 4,5-o-dicaffeoylquinic acid methyl ester on serum uric acid levels in potassium oxonate-pretreated rats. Biol Pharm Bull. 2005;28:2231–2234.
  • Lowry OH, Rosenbrough NJ, Farr AL, Randell RJ. Protein measurement with folin-phenol reagent. J Biol Chem. 1951;193:265–275.
  • Newman DJ, Price CP. Renal function and nitrogen metabolites. In: Burtis CA, Ashwood ER, eds. Tietz Textbook of Clinical Chemistry. Philadelphia, PA: WB Saunders Company; 1999:1204–1270.
  • Gehrig JJ Jr., Jamison RL, Baylis C, Troy JL, Brenner BM, Jamison RL. Effect of intermittent feeding on renal hemodynamics in conscious rats. Am J Physiol. 1986;250:F566–F572.
  • Agarwal R. Rapid microplate method for PAH estimation. Am J Physiol Renal Physiol. 2002;283: F236–F241.
  • Srere PA. Citrate synthase. In: Lowenstein JM, ed. Methods in Enzymology. New York: Academic Press; 1969:3–5.
  • Vinay P, Gougoux A, Lemieux G. Isolation of a pure suspension of rat proximal tubules. Am J Physiol. 1981;241:F403–F411.
  • Poortmans JR, Labilloy D. The influence of work intensity on postexercise proteinuria. Eur J Appl Physiol Occup Physiol. 1988;57:260–263.
  • Middlekauff HR, Nitzsche EU, Nguyen AH, Hoh CK, Gibbs GG. Modulation of renal cortical blood flow during static exercise in humans. Circ Res. 1997;80:62–68.
  • Nakagawa T, Mazzali M, Kang DH, Hyperuricemia causes glomerular hypertrophy in the rat. Am J Nephrol. 2003;23:2–7.
  • Nakagawa T, Mazzali M, Kang DH, Sanchez-Lozada LG, Herrera-Acosta J, Johnson RJ. Uric acid-a uremic toxin?. Blood Purif. 2006;24:67–70.
  • Hosoyamada M, Ichida K, Enomoto A, Hosoya T, Endou H. Function and localization of urate transporter 1 in mouse kidney. J Am Soc Nephrol. 2004;15:261–268.
  • Han HJ, Lim MJ, Lee YJ, Lee JH, Yang IS, Taub M. Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kappaB. Am J Physiol Renal Physiol. 2007;292:F373–F381.

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