424
Views
4
CrossRef citations to date
0
Altmetric
Brief Report

Isoenzyme A and Urinary N-Acetyl-β-D-Glucosaminidase Activity in Normal Pregnancy

, &
Pages 650-653 | Received 28 Mar 2011, Accepted 26 Apr 2011, Published online: 10 Jun 2011

REFERENCES

  • Prince RG. Urinary enzymes, nephrotoxicity and renal diseases. Toxicology. 1982;23:99–134.
  • Han WK, Bonventre JW. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care. 2004;10:476–482.
  • Han WK, Waikar SS, Johnson A, . Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int. 2008;73(7):863–869.
  • Hayashi M, Ueda Y, Hoshimoto K, . Changes in urinary excretion of six biochemical parameters in normotensive pregnancy and preeclampsia. Am J Kidney Dis. 2002;39:392–400.
  • Skálová S. The diagnostic role of urinary N-acetyl-beta-d-glucosaminidase (NAG) activity in the detection of renal tubular impairment. Acta Medica (Hradec Kralove). 2005;48(2):75–80.
  • D’Amico G, Bazzi C. Urinary protein and enzyme excretion as markers of tubular damage. Curr Opin Nephrol Hypertens. 2003;12:639–643.
  • Dance N, Price RG, Robinson D, . β-Galactosidase, β-glucosaminidase and N-acetyl-β-glucosaminidase in human kidney. Clin Chim Acta. 1969;24:189–197.
  • Pugh D, Walker PG. The localization of N-acetyl-β-d-glucosaminidase in tissues. J Histochem Cytochem. 1961;9:242–250.
  • Cheung CK, Lao T, Swaminathan R. Urinary excretion of some proteins and enzymes during normal pregnancy. Clin Chem. 1989;35:1978–1980.
  • Strigini F, Melis GB, Gasperini M, . Urinary excretion of N-acetyl-β-d-glucosaminidase and alanine aminopeptidase during pregnancy. Int J Gynaecol Obstet. 1989;28:9–12.
  • Skra J, Perusicova J, Sperl M, . N-Acetyl-β-glucosaminidase and albuminuria in normal and diabetic pregnancies. Clin Chim Acta. 1989;182:281–287.
  • Hultberg B, Isaksson A, Krutzen E, . Urinary excretion of N-acetyl-β-d-glucosaminidase in normal and complicated pregnancy. J Clin Chem Clin Biochem. 1989;27:487–489.
  • Yoshida M, Furiya K, Takakuwa Y. Urinary excretion of N-acetyl-β-d-glucosaminidase during normal pregnancy. Clin Chim Acta. 1995;235:113–115.
  • Hayashi M, Tomobe K, Hirabayashi H, Hoshimoto K, Ohkura T, Inaba N. Increased excretion of N-acetyl-β-d-glucosaminidase and β2-microglobulin in gestational week 30. Am J Med Sci. 2001;321:168–172.
  • Jacob M, Balasubramaniam N. Excretion of urinary enzymes in normal pregnancy. Clin Biochem. 2006;39:754–757.
  • Ellis BG, Tucker SM, Thompson AE, Price RG. Presence of serum and tissue forms of N-acetyl-beta-glucosaminidase in urine from patients with renal disease. Clin Chim Acta. 1975;64:195–202.
  • Orlacchio A, Maffei C, Emiliani C, Rambotti P, Davis S. A distinct β-hexosaminidase isoenzymes separated from human leukemic lymphocytes and myelocytes. Biochem Biophys Res Commun. 1984;122:966–973.
  • Neufeld EF. Natural history and inherited disorders of a lysosomal enzyme β-hexosaminidase. J Biol Chem. 1989;264:10927–10930.
  • Price RG. Measurement of N-acetyl-beta-glucosaminidase and its isoenzymes in urine: Methods and clinical applications. Eur J Clin Chem Clin Biochem. 1992;30:693–695.
  • Pérez LF, Tutor JC. Assay of serum/plasma β-N-acetylhexosaminidase isoenzymes by heat inactivation using a continuous spectrophotometric method adapted to a centrifugal analyzer. Eur J Clin Chem Clin Biochem. 1977;35:445–452.
  • Numata Y, Morita A, Kosugi Y, Shibata K, Takeuchi N, Uchida K. New sandwich ELISA for human urinary N-acetyl-beta-d-glucosaminidase isoenzyme B as a useful clinical test. Clin Chem. 1997;43:569–574.
  • Morita A, Numata Y, Kosugi Y, Noto A, Takeuchi N, Uchida K. Stabilities of N-acetyl-β-d-glucosaminidase (NAG) isoenzymes in urine: Advantage of NAG isoenzyme B measurement in clinical application. Clin Chim Acta. 1998;278:35–43.
  • Tassi C, Angelini A, Beccari T, Capodicasa E. Fluorimetric determination of activity and isoenzyme composition of N-acetyl-β-d-glucosaminidase in seminal plasma of fertile men and infertile patients with secretory azoospermia. Clin Chem Lab Med. 2006;44:843–847.
  • Kytzia HJ, Sandhoff K. Evidence of two different active sites on β-hexosaminidase A. J Biol Chem. 1985;260:7568–7572.
  • Tassi C, Beccari T, Casini A, Orlacchio A. β-N-Acetylhexosaminidase in the urine, kidney and serum of bromobenzene-intoxicated mice. Clin Chim Acta. 1992;206:231–239.
  • Costanzi E, Beccari T, Francisci D, Orlacchio A, Tassi C. Lysosomal hydrolases in serum from human immunodeficiency virus-infected patients. Clin Chim Acta. 1996;255:231–239.
  • Tassi C, Abbritti G, Mancuso F, Morucci P, Feligoni L, Muzi G. Activity and isoenzyme profile of N-acetyl-β-d-glucosaminidase in urine from workers exposed to cadmium. Clin Chim Acta. 2000;299:55–64.
  • Paigen K, Peterson J. Coordinacy of lysosomal enzyme excretion in human urine. J Clin Invest. 1978;61:751–762.
  • Gibey R, Dupond JL, Peltier H, Iehl-Robert M, Henry JC. An early and specific indicator of aminoglycoside nephrotoxicity: Isoenzyme B of urinary N-acetyl-beta-d-glucosaminidase (NAG). Pathol Biol (Paris). 1986;34:342–345.
  • Beccari T, Emiliani C, Hosseini R, Orlacchio A, Stirling JL. Intermediate forms of human β-N-acetylglucosaminidase lack activity towards 4-methylumbelliferyl-β-acetylglucosamine-6-sulphate. Biochem J. 1987;244:801–804.
  • Henry RH. Creatinine in Clinical Chemistry. Principles and Techniques. New York: Harper and Row (Hoeber Medical Division); 1964:292–299.
  • Baylis C, Davison JM. Renal physiology in normal pregnancy. In: Feehally J, Floege J, Johnson RJ, eds. Comprehensive Clinical Nephrology. 3rd ed., Philadelphia, PA: Mosby Elsevier, Inc.; 2007:475–481.
  • Karamanchi SA, Epstein FH. Renal complication in pregnancy. In: Feehally J, Floege J, Johnson RJ, eds. Comprehensive Clinical Nephrology. 3rd ed., Philadelphia, PA: Mosby Elsevier, Inc.; 2007:483–493.
  • Cheung CK, Lao T, Swaminathan R. Urinary excretion of some proteins and enzymes during normal pregnancy. Clin Chem. 1989;35(9):1978–1980.
  • Rogers MS, Arumanayagam M, Fug H, Lau TK. Diurnal variation in excretion of N-acetyl-beta-d-glucosaminidase during pregnancy: Implication for the prediction of pre-eclampsia. Gynecol Obstet Invest. 1999;47:9–12.
  • Bondiou MT, Bourbouze R, Bernard M, Percheron F, Perez-Gonzales N, Cabezas JA. Inhibition of A and B N-acetyl-β-d-glucosaminidase urinary isoenzymes by urea. Clin Chim Acta. 1985;149:67–73.
  • Wellwood M, Price RG, Ellis BG, Thompson AE. A note on the practical aspects of the assay of N-acetyl-β-glucosaminidase. Clin Chim Acta. 1976;69:85–91.
  • Brown MA. Urinary tract dilatation in pregnancy. Am J Obstet Gynecol. 1990;164:641–643.
  • Brown M, Gallery EDM. Volume homeostasis in normal pregnancy and preeclampsia. Physiology and clinical implication. Clin Obstet Gynecol. 1994;8:287–310.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.