References
- Schlondorff D. The glomerular mesangial cell: an expanding role for a specialized pericyte. FASEB J. 1987;1:272–281
- Jiao S, Meng F, Zhang J, Yang X, Zheng X, Wang L. STAT1 mediates cellular senescence induced by angiotensin II and H2O2 in human glomerular mesangial cells. Mol Cell Biochem. 2012;365:9–17
- Aihara K, Ikeda Y, Yagi S, Akaike M, Matsumoto T. Transforming growth factor-beta1 as a common target molecule for development of cardiovascular diseases, renal insufficiency and metabolic syndrome. Cardiol Res Pract. 2011;2011:175381 9 pp. doi: 10.4061/2011/175381.
- Desmouliere A, Darby IA, Gabbiani G. Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest. 2003;83:1689–1707
- Schnaper HW, Jandeska S, Runyan CE, et al. TGF-beta signal transduction in chronic kidney disease. Front Biosci. 2009;14:2448–2465
- Lopez-Novoa JM, Rodriguez-Pena AB, Ortiz A, Martinez-Salgado C, Lopez Hernandez FJ. Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications. J Transl Med. 2011;9:13. 24 pp
- Hayashida T, Poncelet AC, Hubchak SC, Schnaper HW. TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression. Kidney Int. 1999;56:1710–1720
- Dorado F, Velasco S, Esparis-Ogando A, et al. The mitogen-activated protein kinase Erk5 mediates human mesangial cell activation. Nephrol Dial Transplant. 2008;23:3403–3411
- Kimura K, Iwano M. Molecular mechanisms of tissue fibrosis. Nihon Rinsho Meneki Gakkai Kaishi. 2009;32:160–167
- Lee DH, Wolstein JM, Pudasaini B, Plotkin M. INK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2012;302:F183–F191
- Verzola D, Gandolfo MT, Gaetani G, et al. Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy. Am J Physiol Renal Physiol. 2008;295:F1563–F1573
- Koppelstaetter C, Schratzberger G, Perco P, et al. Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation. Aging Cell. 2008;7:491–497
- Braun H, Schmidt BM, Raiss M, et al. Cellular senescence limits regenerative capacity and allograft survival. J Am Soc Nephrol. 2012;23:1467–1473
- Sis B, Tasanarong A, Khoshjou F, Dadras F, Solez K, Halloran PF. Accelerated expression of senescence associated cell cycle inhibitor p16INK4A in kidneys with glomerular disease. Kidney Int. 2007;71:218–226
- Sterzel RB, Schulze-Lohoff E, Marx M. Cytokines and mesangial cells. Kidney Int Suppl. 1993;39:S26–S31
- Das F, Ghosh-Choudhury N, Kasinath BS, Choudhury GG. TGFbeta enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy. FEBS Lett. 2010;584:4268–4272
- Stephenson LA, Haney LB, Hussaini IM, Karns LR, Glass WF 2nd. Regulation of smooth muscle alpha-actin expression and hypertrophy in cultured mesangial cells. Kidney Int. 1998;54:1175–1187
- Bariety J, Hill GS, Mandet C, et al. Glomerular epithelial-mesenchymal transdifferentiation in pauci-immune crescentic glomerulonephritis. Nephrol Dial Transplant. 2003;18:1777–1784
- Bedi S, Vidyasagar A, Djamali A. Epithelial-to-mesenchymal transition and chronic allograft tubulointerstitial fibrosis. Transplant Rev (Orlando). 2008;22:1–5
- Piera-Velazquez S, Li Z, Jimenez SA. Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders. Am J Pathol. 2011;179:1074–1080
- Li J, Bertram JF. Review: Endothelial-myofibroblast transition, a new player in diabetic renal fibrosis. Nephrology (Carlton). 2010;15:507–512
- Li J, Qu X, Bertram JF. Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol. 2009;175:1380–1388