740
Views
2
CrossRef citations to date
0
Altmetric
Research Article

A meta-analysis on the relationship of eNOS 4b/a polymorphism and diabetic nephropathy susceptibility

, , , , , , & show all
Pages 1520-1535 | Received 05 May 2014, Accepted 04 Aug 2014, Published online: 08 Oct 2014

References

  • Ritz E, Rychlík I, Locatelli F, Halimi S. End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions. Am J Kidney Dis. 1999;34(5):795–808
  • Newman DJ, Mattock MB, Dawnay ABS, et al. Systematic review on urine albumin testing for early detection of diabetic complications. Health Technol Assess. 2005;9(30):iii–vi, xiii–163
  • Shpichinetsky V, Raz I, Friedlander Y, et al. The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients. J Nutr. 2000;130(10):2493–2497
  • Zintzaras E, Uhlig K, Koukoulis GN, Papathanasiou AA, Stefanidis I. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: A meta-analysis. J Hum Genet. 2007; 52(11):881–890
  • Nakagawa T. Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: An explanation for the paradoxical effects of VEGF in renal disease. Am J Physiol Renal Physiol. 2007;292(6):F1665–F1672
  • Palm F, Teerlink T, Hansell P. Nitric oxide and kidney oxygenation. Curr Opin Nephrol Hypertens. 2009;18(1):68–73
  • Noiri E, Satoh H, Taguchi J-I, et al. Association of eNOS Glu298Asp polymorphism with end-stage renal disease. Hypertension. 2002;40(4):535–540
  • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med. 1993;329(27):2002–2012
  • Star RA. Intrarenal localization of nitric oxide synthase isoforms and soluble guanylyl cyclase. Clin Exp Pharmacol Physiol. 1997;24(8):607–610
  • Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J. 1994;298(Pt 2):249–258
  • Alderton W, Cooper C, Knowles R. Nitric oxide synthases: Structure, function and inhibition. Biochem J. 2001;357:593–615
  • Augeri AL, Tsongalis GJ, Van Heest JL, Maresh CM, Thompson PD, Pescatello LS. The endothelial nitric oxide synthase -786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure. Atherosclerosis. 2009;204(2):e28–e34
  • Wolff B, Braun C, Schlter C, et al. Endothelial nitric oxide synthase Glu298→Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample. Clin Sci. 2005;109:475–481
  • Sinici I, Atalar E, Kepez A, et al. Intron 4 VNTR polymorphism of eNOS gene is protective for cardiac syndrome X. J Investig Med. 2010;58(1):23–27
  • Rahimi Z, Shahvaisi-Zadeh F, Sadeghei S, Vessal M, Yavari N. eNOS 4a/b polymorphism and its interaction with eNOS G894T variants in type 2 diabetes mellitus: Modifying the risk of diabetic nephropathy. Dis Markers. 2013;34(6):437–443
  • Santos KG, Crispim D, Canani LH, Ferrugem PT, Gross JL, Roisenberg I. Association of eNOS gene polymorphisms with renal disease in Caucasians with type 2 diabetes. Diabetes Res Clin Pract. 2011;91(3):353–362
  • Ezzidi I, Mtiraoui N, Mohamed MB, Mahjoub T, Kacem M, Almawi WY. Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T>C gene variants with diabetic nephropathy. J Diabetes Complications. 2008;22(5):331–338
  • Neugebauer S, Baba T, Watanabe T. Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes. Diabetes. 2000;49(3):500–503
  • Definition, W. H. O. Part 1: Diagnosis and Classification of Diabetes Mellitus. Definition, Diagnosis and Classification of Diabetes Mellzitus and its Complications. Geneva: World Health Organization, Department of Noncommunicable Disease Surveillance; 1999
  • Xue J, Chen LZ, Xue L, Zhou Q. Meta-analysis of risk factors for childhood cerebral palsy during pregnancy. CJCP. 2013;15(7):535–540
  • Deeks JJ, Dinnes J, D’Amico R, et al. Evaluating non-randomised intervention studies. Health Technol Assess. 2003;7(27):1–173
  • Wells G, Shea B, O’Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. 2010. Available at: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. Accessed July 2014
  • Yang YL, Liu L, Wang Y, et al. The prevalence of depression and anxiety among Chinese adults with cancer: A systematic review and meta-analysis. BMC Cancer. 2013;13:393
  • University of Thessaly, School of Medicine Laboratory of Biomathematics. Revealing the Mode of Inheritance in Genetic Association Studies. Available at: http://www.doc88.com/p-579886058890.html. Accessed April 2014
  • Borenstein M, Hedges LV, Higgins JP, Rothstein HR. Part 3: Fixed-Effect Versus Random-Effects Models. Introduction to Meta-Analysis. Englewood: Wiley; 2011
  • Alderson P, Creen S, Higgins JPT. Cochrane Reviewer’s Handbook4.2.2 (update MSTVH2004). Cochrane Library. Issue 1. Chechester: Wiley; 2004
  • Garn SM. Human Races. Illinois: Thomas; 1971
  • Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–634
  • Wang SL. Study of the Susceptibility Genes of Type 2 Diabetic Nephropathy in Northern Chinese. Shandong: Shandong University; 2005
  • Miao L. Association of Nitric Oxide Synthase Gene Polymorphism with Diabetic Nephropathy in Type 2 Diabetic Patients. Shandong: Shandong University; 2003
  • Dong YH, Qu SP, Lü WS, et al. Gene polymorphism in chromosome 7q35 and susceptibility to diabetic nephropathy. Chin J Diabetes. 2005;21(1):47–50
  • Luo H, Ning YY. Association of polymorphism of endothelialnitricoxide synthase gene with diabetic nephropathy. Chin J Diabetes. 2003;11(5):317–320
  • Shestakova M, Vikulova O, Gorashko N, et al. The relationship between genetic and hemodynamic factors in diabetic nephropathy (DN): Case–control study in type 1 diabetes mellitus (T1DM). Diabetes Res Clin Pract. 2006;74(2):S41–S50
  • Li C, Dong Y, Lü W. [The association between polymorphism of endothelial nitric oxide synthase gene and diabetic nephropathy]. Zhonghua nei ke za zhi [Chin J Intern Med]. 2001;40(11):729–732
  • Rippin J, Patel A, Belyaev N, Gill G, Barnett A, Bain S. Nitric oxide synthase gene polymorphisms and diabetic nephropathy. Diabetologia. 2003;46(3):426–428
  • Mehrab-Mohseni M, Tabatabaei-Malazy O, Hasani-Ranjbar S, et al. Endothelial nitric oxide synthase VNTR (intron 4 a/b) polymorphism association with type 2 diabetes and its chronic complications. Diabetes Res Clin Pract. 2011;91(3):348–352
  • Shoukry A, Shalaby SM, Abdelazim S, et al. Endothelial nitric oxide synthase gene polymorphisms and the risk of diabetic nephropathy in type 2 diabetes mellitus. Genet Test Mol Biomarkers. 2012;16(6):574–579
  • Degen B, Schmidt S, Ritz E. A polymorphism in the gene for the endothelial nitric oxide synthase and diabetic nephropathy. Nephrol Dial Transplant. 2001;16(1):185–198
  • Shimizu T, Onuma T, Kawamori R, Makita Y, Tomino Y. Endothelial nitric oxide synthase gene and the development of diabetic nephropathy. Diabetes Res Clin Pract. 2002;58(3):179–185
  • Ahluwalia TS, Ahuja M, Rai TS, et al. Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians. Mol Cell Biochem. 2008;314(1–2):9–17
  • Ksiazek P, Wojewoda P, Muc K, Buraczynska M. Endothelial nitric oxide synthase gene intron 4 polymorphism in type 2 diabetes mellitus. Mol Diagn. 2003;7(2):119–123
  • Sun H-Y, Yang M, Liu S, Wang C, Zhang Q, Chen M. Study on the correlation of the polymorphisms of endothelial nitric oxide synthase gene with type 2 diabetes mellitus and diabetic nephropathy. Chin J Prev Contr Chron Non-Commun Dis. 2004;12(3):101–103
  • Möllsten A, Wessman M, Svensson M, et al. Glu298Asp and NOS4ab polymorphisms in diabetic nephropathy. Ann Med. 2006;38(7):522–528
  • Fujita H, Narita T, Meguro H, et al. Lack of association between an ecNOS gene polymorphism and diabetic nephropathy in type 2 diabetic patients with proliferative diabetic retinopathy. Horm Metab Res. 2000;32(2):80–83
  • Lin S, Qu HQ, Qiu MC. Study on the association between ecNOS4b/a polymorphism and diabetic nephropathy. Chin J Nephrol. 2002;18(4):258–261
  • Zhang M, Liu H, Yang HY, Wang YM, Song DP, Li H. Relationship of endothelial nitric oxide synthase (eNOS) 4a/b gene polymorphism with diabetic nephropathy. Chin J Diabetes. 2005;11(4):284–285
  • Ma JR. Study on the Relationship between the Endothelial Constitutive Nitric Oxide Synthase (ecNOS) Gene Polymorphism and the Development of Diabetic Vascular Complication in Type 2 Diabetic Patients. Tianjin: Tianjin Medical University; 2003
  • Guo XJ, Liu SJ. The association between endothelial nitric oxide synthase gene polymorphism and type 2 diabetic nephropathy. China Healthc Innovat. 2012;6(19):3–5
  • Xing Q, Su BL, Li CC, et al. Association between endothelial nitric oxide synthase gene polymorphism and type 2 diabetic nephropathy. Chin J Endocrinol Metab. 2004;20(5):435–437
  • Dong J, Zhao J, Lee K, Lir M, Chan S, Liao L. [Distribution of polymorphism in endothelial nitric oxide synthase gene in Singapore Chinese and its association with diabetic nephropathy]. Zhonghua yi xue za zhi. 2007;87(48):3415–3417
  • Turner R, Holman R, Cull C, et al. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352(9131):837–853
  • He Y, Fan Z, Zhang J, et al. Polymorphisms of eNOS gene are associated with diabetic nephropathy: A meta-analysis. Mutagenesis. 2011;26(2):339–349
  • Nakagawa T, Sato W, Glushakova O, et al. Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol. 2007;18(2):539–550
  • Masuda Y, Shimizu A, Mori T, et al. Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis. Am J Pathol. 2001;159(2):599–608
  • Ziche M, Morbidelli L, Choudhuri R, et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest. 1997;99(11):2625–2634
  • Brodsky SV, Gao S, Li H, Goligorsky MS. Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cells. Am J Physiol Heart Circ Physiol. 2002;283(5):H2130–H2139
  • Zheng X, Lou J, Yang W. Role of nitric oxide on diabetic nephropathy. Chinese J Nephrol. 1999;2:1–113
  • Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world—A growing challenge. N Eng J Med. 2007;356(3):213–215
  • Liu M. Susceptibility Genes, Environmental Risk Factors and their Interactions in the Development of Type 2 Diabetes Mellitus. Wuhan:Huazhong University of Science and Technology; 2006

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.