References
- Farris AB, Colvin RB. Renal interstitial fibrosis: Mechanisms and evaluation. Curr Opin Nephrol Hypertens. 2012;21:289–300
- Zeisberg M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol. 2010;21:1819–1834
- Boor P, Ostendorf T, Floege J. Renal fibrosis: Novel insights into mechanisms and therapeutic targets. Nat Rev Nephrol. 2010;6:643–656
- Walter P, Ron D. The unfolded protein response: From stress pathway to homeostatic regulation. Science. 2011;334:1081–1086
- Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007;8:519–529
- Chiang CK, Hsu SP, Wu CT, et al. Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol Med. 2011;17:1295–1305
- Tanjore H, Lawson WE, Blackwell TS. Endoplasmic reticulum stress as a pro-fibrotic stimulus. Biochim Biophys Acta. 2013;1832:940–947
- Inagi R, Ishimoto Y, Nangaku M. Proteostasis in endoplasmic reticulum – New mechanisms in kidney disease. Nat Rev Nephrol. 2014;10:369–378
- Hon CC, Chow YC, Zeng FY, Leung FC. Genetic authentication of ginseng and other traditional Chinese medicine. Acta Pharmacol Sin. 2003;24:841–846
- Qi LW, Wang CZ, Yuan CS. Ginsenosides from American ginseng: Chemical and pharmacological diversity. Phytochemistry. 2011;72:689–699
- Wei HJ, Yang HH, Chen CH, et al. Gelatin microspheres encapsulated with a nonpeptide angiogenic agent, ginsenoside Rg1, for intramyocardial injection in a rat model with infarcted myocardium. J Control Release. 2007;120:27–34
- Geng J, Peng W, Huang Y, Fan H, Li S. Ginsenoside-Rg1 from Panax notoginseng prevents hepatic fibrosis induced by thioacetamide in rats. Eur J Pharmacol. 2010;634:162–169
- Ma FY, Tesch GH, Ozols E, Xie M, Schneider MD, Nikolic-Paterson DJ. TGF-β1-activated kinase-1 regulates inflammation and fibrosis in the obstructed kidney. Am J Physiol Renal Physiol. 2011;300:F1410–F1421
- Xie XS, Liu HC, Wang FP, et al. Ginsenoside Rg1 modulation on thrombospondin-1 and vascular endothelial growth factor expression in early renal fibrogenesis in unilateral obstruction. Phytother Res. 2010;24:1581–1587
- Remuzzi G, Zoja C, Gagliardini E, Corna D, Abbate M, Benigni A. Combining an antiproteinuric approach with mycophenolate mofetil fully suppresses progressive nephropathy of experimental animals. J Am Soc Nephrol. 1999;10:1542–1549
- Mizuguchi Y, Miyajima A, Kosaka T, Asano T, Asano T, Hayakawa M. Atorvastatin ameliorates renal tissue damage in unilateral ureteral obstruction. J Urol. 2004;172:2456–2459
- Kitamura M. The unfolded protein response triggered by environmental factors. Semin Immunopathol. 2013;35:259–275
- Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: Cell life and death decisions. J Clin Invest. 2005;115:2656–2664
- Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol. 2011;13:184–190
- Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep. 2006;7:880–885
- Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol. 2000;150:887–894
- Fang L, Xie D, Wu X, Cao H, Su W, Yang J. Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells. PLoS One. 2013;8:e72344
- Johnson A, DiPietro LA. Apoptosis and angiogenesis: An evolving mechanism for fibrosis. FASEB J. 2013;27:3893–3901
- Inagi R. Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury. Nephron Exp Nephrol. 2009;112:e1–e9
- Inagi R. Endoplasmic reticulum stress as a progression factor for kidney injury. Curr Opin Pharmacol. 2010;10:156–165
- Yeh CH, Chiang HS, Lai TY, Chien CT. Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat. Neurourol Urodyn. 2011;30:472–479
- Xie XS, Yang M, Liu HC, et al. Influence of ginsenoside Rg1, a panaxatriol saponin from Panax notoginseng, on renal fibrosis in rats with unilateral ureteral obstruction. J Zhejiang Univ Sci B. 2008;9:885–894