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Pediatric Hematology and Oncology Volume 31, 2014 - Issue 2
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LETTER TO THE EDITOR Acute Lymphoblastic Leukemias

Congenital Acute Lymphoblastic Leukemia Case with a Novel t(2:4:11) (p21:q21:q23) Translocation

Emmanuel HatzipantelisPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, Greece
, MD, PhD,
Zoe Dorothea PanaPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, GreeceCorrespondence[email protected]
, MD, MSc,
Theodotis PapageorgiouPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, Greece
, MD, PhD,
Maria HatzistilianouPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, Greece
, MD, PhD,
Anastasia AthanasiadouHematology Department and BMT Unit, General Hospital of Papanicolaou, Thessaloniki, Greece
, MD, PhD,
Kosmas Sarafidis1st Department of Neonatology of Aristotle University, Hippokration General Hospital, Thessaloniki, Greece
, MD, PhD,
Vasiliki TsotoulidouPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, Greece
, MD,
George PapaioannouHematology Department and BMT Unit, General Hospital of Papanicolaou, Thessaloniki, Greece
, MD &
Fani AthanassiadouPediatric Hematology Oncology Unit, 2nd Pediatric Department of Aristotle University, AHEPA General Hospital, Thessaloniki, Greece
, MD, PhD show all
Pages 178-180 | Received 19 Jul 2013, Accepted 25 Aug 2013, Published online: 25 Nov 2013

REFERENCES

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  • Pui CH, Behm FG, Downing JR, 11q23/MLL rearrangement confers a poor prognosis in infants with acute lymphoblastic leukemia. J Clin Oncol. 1994;12:909–915.
  • Tauchi H, Tomizawa D, Eguchi M, Clinical features and outcome of MLL gene rearranged acute lymphoblastic leukemia in infants with additional chromosomal abnormalities other than 11q23 translocation. Leukemia Res. 2008;32:1523–1529.
  • Kowarz E, Burmeister T, Lo Nigro L, Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4.MLL fusion allele. Leukemia. 2007;21:1232–1238.
  • Coenen EA, Raimondi SC, Harbott J, Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study. Blood. 2011;117:7102–7111.

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