Distinct role of T helper Type 17 immune response for Graves' hyperthyroidism in mice with different genetic backgrounds

References

• Rees Smith B, McLachlan SM, Furmaniak J. Autoantibodies to the thyrotropin receptor. Endocr Rev. 1988; 9:106–121.
   PubMed Web of Science ®Google Scholar
• Rapoport B, Chazenbalk GD, Jaume JC, McLachlan SM. The thyrotropin (TSH) receptor: Interaction with TSH and autoantibodies. Endocr Rev. 1998; 19:673–716.
   PubMed Web of Science ®Google Scholar
• Weetman AP, Yateman ME, Ealey PA, Black CM, Reimer CB, Williams RCJr, Shine B, Marshall NJ. Thyroid-stimulating antibody activity between different immunoglobulin G subclasses. J Clin Invest. 1990; 86:723–727.
   PubMed Web of Science ®Google Scholar
• Latrofa F, Chazenbalk GD, Pichurin P, Chen CR, McLachlan SM, Rapoport B. Affinity-enrichment of thyrotropin receptor autoantibodies from Graves' patients and normal individuals provides insight into their properties and possible origin from natural antibodies. J Clin Endocrinol Metab. 2004; 89:4734–4745.
   PubMed Web of Science ®Google Scholar
• McLachlan SM, Nagayama Y, Rapoport B. Insight into Graves' hyperthyroidism from animal models. Endocr Rev. 2003; 26:800–832.
   Web of Science ®Google Scholar
• Nagayama Y, Mizuguchi H, Hayakawa T, Niwa M, McLachlan SM, Rapoport B. Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine. J Immunol. 2003; 170:3522–3527.
   PubMed Web of Science ®Google Scholar
• Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005; 6:1123–1132.
   PubMed Web of Science ®Google Scholar
• Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005; 6:1133–1141.
   PubMed Web of Science ®Google Scholar
• Horie I, Abiru N, Nagayama Y, Saitoh O, Ichikawa T, Iwakura Y, Eguchi K. T helper type 17 immune response plays an indispensable role for development of experimental autoimmune thyroiditis in NOD-H2h4 mice. Endocrinology. 2009; 150:5135–5142.
   PubMed Web of Science ®Google Scholar
• Figueroa-Vega N, Alfonso-Perez M, Benedicto I, Sanchez-Madrid F, Gonzalez-Amaro R, Marazuela M. Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis. J Clin Endocrinol Metab. 2010; 95:953–962.
   PubMed Web of Science ®Google Scholar
• Nagayama Y, Kita-Furuyama M, Nakao K, Ando T, Mizuguchi H, Hayakawa T, Eguchi K, Niwa M. A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing thyrotropin receptor. J Immunol. 2002; 168:2789–2794.
   PubMed Web of Science ®Google Scholar
• Chen CR, Pichurin P, Nagayama Y, Latrofa F, Rapoport B, McLachlan SM. The thyrotropin receptor autoantigen in Graves' disease is the culprit as well as the victim. J Clin Invest. 2003; 111:1897–1904.
   PubMed Web of Science ®Google Scholar
• Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I, Sekikawa K, Asano M, Iwakura Y. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity. 2002; 17:375–387.
   PubMed Web of Science ®Google Scholar
• Mizutori Y, Saitoh O, Eguchi K, Nagayama Y. Adenovirus coding the thyrotropin receptor A subunit improves the efficacy of dendritic cell-based mouse model of Graves' hyperthyroidism. J Autoimmun. 1996; 26:32–36.
   Google Scholar
• Chazenbalk GD, Kakinuma A, Jaume JC, McLachlan SM, Rapoport B. Evidence for negative cooperativity among human thyrotropin receptors overexpressed in mammalian cells. Endocrinology. 1996; 137:4586–4591.
   PubMed Web of Science ®Google Scholar
• Saitoh O, Abiru N, Nakahara M, Nagayama Y. CD8+CD122+ T cells, a newly identified regulatory T cells, negatively regulate Graves' disease in a murine model. Endocrinology. 2007; 148:6040–6046.
   PubMed Web of Science ®Google Scholar
• McLachlan SM, Braley-Mullen H, Chen C-R, Aliesky H, Pichurin PN, Rapoport B. Dissociation between iodide-induced thyroiditis and antibody-mediated hyperthyroidism in NOD.H-2h4 mice. Endocrinology. 2005; 146:294–300.
   PubMed Web of Science ®Google Scholar
• Ito R, Kita M, Shin-Ya M, Kishida T, Urano A, Takada R, Sakagami J, Imanishi J, Iwakura Y, Okanoue T, Yoshikawa T, Kataoka K, Mazda O. Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice. Biochem Biophys Res Commun. 2008; 377:12–16.
   PubMed Web of Science ®Google Scholar
• Ogawa A, Andoh A, Araki Y, Bamba T, Fujiyama Y. Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice. Clin Immunol. 2004; 110:55–62.
   PubMed Web of Science ®Google Scholar
• Melgar S, Karlsson A, Michaëlsson E. Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: Correlation between symptoms and inflammation. Am J Physiol Gastrointest Liver Physiol. 2005; 288:1328–1338.
   PubMed Web of Science ®Google Scholar
• Amadi-Obi A, Yu CR, Liu X, Mahdi RM, Clarke GL, Nussenblatt RB, Gery I, Lee YS, Egwuagu CE. TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nat Med. 2007; 13:711–718.
   PubMed Web of Science ®Google Scholar
• Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Ohsugi Y, Mamura M, Goto D, Ito S, Tsutsumi A, Kishimoto T, Simada T. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphatase isomerase. Arthritis Rheum. 2008; 58:754–763.
   PubMed Web of Science ®Google Scholar
• Nagayama Y, Saitoh O, McLachlan SM, Rapoport B, Kano H, Kumazawa Y. TSH receptor-adenovirus-induced Graves' hyperthyroidism is attenuated in both interferon-gamma and interleukin-4 knockout mice; implications for the Th1/Th2 paradigm. Clin Exp Immunol. 2004; 138:417–422.
   PubMed Web of Science ®Google Scholar
• Komiyama Y, Nakae S, Matsuki T, Nambu A, Ishigame H, Kakuta S, Sudo K, Iwakura Y. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol. 2006; 177:566–573.
   PubMed Web of Science ®Google Scholar
• O'Conner WJr, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol. 2009; 10:603–609.
   PubMed Web of Science ®Google Scholar
• Luger D, Silver PB, Tang J, Cua D, Chen Z, Iwakura Y, Bowman EP, Sgambellone NM, Chan CC, Caspi RR. Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category. J Exp Med. 2008; 205:799–810.
   PubMed Web of Science ®Google Scholar
• Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan C-C, Gery I. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J Immunol. 2008; 180:7414–7422.
   PubMed Web of Science ®Google Scholar
• Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med. 2008; 205:1535–1541.
   PubMed Web of Science ®Google Scholar
• Martin-Orozco N, Chung Y, Chang SH, Wang YH, Dong C. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur J Immunol. 2009; 39:216–224.
   PubMed Web of Science ®Google Scholar
• Bending D, De La Peña H, Veldhoen M, Phillips JM, Uyttenhove C, Stockinger B, Cooke A. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest. 2009; 119:565–572.
   PubMedGoogle Scholar