Effects of Prolonged Administration of the 19-NOR-Testosterone Derivatives Norethindrone and Norgestrel to Female NZB/W Mice: Comparison with Medroxyprogesterone and Ethinyl Estradiol

References

• Dubois E L. The clinical picture of systemic lupus erythema- tosus. Lupus Erythematosus, E L Dubois. University of California Press, Los Angeles 1974; 232–42
   Google Scholar
• Zurier R B. Systemic lupus erythematosus and pregnancy. Systemic Lupus Erythematosus, R G Lahita. John Wiley and Sons, New York 1987; 541–54
   Google Scholar
• Chapel T A, Burns R E. Oral contraceptives and exacerbation of lupus erythematosus. Am J Obsret Gynecol 1971; 110: 366–9
   PubMed Web of Science ®Google Scholar
• Jungers P, Dougados M, Pelissier C, Kuttenn F, Tron F, Lesavre P, et al. Influence of oral contraceptive therapy on the activity of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 618–23
   PubMed Web of Science ®Google Scholar
• Mintz G, Gutierrez G, Deleze M, Rodriguez E. Contraception with progestagens in systemic lupus erythematosus. Contraception 1984; 30: 29–38
   PubMed Web of Science ®Google Scholar
• Howie J B, Helyer B J. The immunology and pathology of NZB mice. Adv Immunol 1968; 9: 215–66
   PubMedGoogle Scholar
• Steinberg A D, Pincus T, Talal N. DNA-binding assay for detection of anti-DNA antibodies in NZB/NZW F1 mice. J Immunol 1969; 102: 788–790
   PubMed Web of Science ®Google Scholar
• Roubinian J R, Talal N, Greenspan J S, Goodman J R, Siiteri P K. Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med 1978; 147: 1568–83
   PubMed Web of Science ®Google Scholar
• Roubinian J, Talal N, Siiteri P K, Sadakian J A. Sex hormone modulation of autoimmunity in NZB/NZW mice. Arthritis Rheum 1979; 22: 1162–9
   PubMed Web of Science ®Google Scholar
• Verheul H AM, Schot L PC, Deckers G HJ, Schuurs A HWM. Effects of tibolone, lynestrenol, ethylestrenol, and desogestrel on autoimmune disorders in NZB/W mice. Clin Immunol Immunopathol 1986; 8: 198–208
   Google Scholar
• Keisler L W, Walker S E. Suppression of reproductive function in autoimmune NZB/W mice: Effective doses of four contraceptive steroids. Am J Reprod Immunol Microbiol 1987; 14: 115–21
   PubMedGoogle Scholar
• Smith A L, Bottomly K, Winograd D F. Altered splenic T cell function of BALB/cByJ mice infected with mouse hepatitis virus or Sendai virus. J Immunol 1987; 138: 3426–30
   PubMedGoogle Scholar
• Loew F M, Fox J G. Animal health surveillance and health delivery systems. The Mouse in Biomedical Research. Vol 3, H L Foster, J D Small, J G Fox. Academic Press, New York 1983; 69–82
   Google Scholar
• Talal N, Roubinian J R, Dauphinee M J, Jones L A, Siiteri P K (1981) Effects of sex hormones on spontaneous autoimmune disease in NZB/NZW hybrid mice. Advances in Immunopharmacology. Proceedings of the First International Conference on Immunopharmacology. 1981, J Hadden, L Chedid, P Mullen, F Spreafico. Pergamon Press, New York, 127–37
   Google Scholar
• Steinberg A D, Melez K A, Raveche E S, Reeves J P, Boegel W A, Smathers P A, et al. Approach to the study of sex hormones in autoimmunity. Arthritis Rheum 1979; 22: 1170–6
   PubMed Web of Science ®Google Scholar
• Siiteri P K, Jones L A, Roubinian J, Talal N. Sex steroids and the immune system - I. Sex difference in autoimmune disease in NZB/NZW hybrid mice. J Steroid Biochem 1980; 12: 425–32
   PubMedGoogle Scholar
• Walker S E, Bole G G. Augmented incidence of neoplasia in NZB/NZW mice treated with long-term cyclophosphamide. J Lab Clin Med 1973; 82: 619–33
   PubMedGoogle Scholar
• Walker S E, Bole G G. Influence of natural and synthetic estrogens on the course of autoimmune disease in the NZB/NZW mouse. Arthritis Rheum 1973; 16: 231–9
   PubMedGoogle Scholar
• Berden J HM, Hang L, McConahey P J, Dixon F J. Analysis of vascular lesions in murine SLE. J Immunol 1983; 130: 1699–1705
   PubMed Web of Science ®Google Scholar
• Walker S E, Kier A B, Siegfried E C, Harris B G, Schultz J S. Accelerated autoimmune disease and lymphoreticular neoplasms in F1 hybrid PN/NZB and NZB/PN mice. Clin Immunol Immunopathol 1986; 39: 81–92
   PubMedGoogle Scholar
• Collins R D, Cousar J B, Russell W G, Glick A D. Diagnosis of neoplasms of the immune system. Manual of Clinical Immunology. Second edition, N R Rose, H Friedman. Americal Society for Microbiology, Washington, DC 1980; 84–101
   Google Scholar
• Goldenberg G J, Paraskevas F, Israels L G. Lymphocyte and plasma cell neoplasms associated with autoimmune diseases. Semin Arthritis Rheum 1971; 1: 174–93
   PubMedGoogle Scholar
• Della Porta G, Chieco-Bianchi L, Pennelli N. Tumours of the haemopoietic system. Pathology of Tumours in Laboratory Animals. Tumours of the Mouse. Vol 2, V S Turusov. International Agency for Research on Cancer, Lyon 1979; 527–36, Publication no. 23
   Google Scholar
• Walker S E, Solsky M, Schnitzer B. Prolonged lifespans in female NZB/NZW mice treated with the experimental immunoregulatory drug frentizole. Arthritis Rheum 1982; 25: 1291–7
   PubMedGoogle Scholar
• Walker S E, Bole G G. Selective suppression of autoantibody responses in NZB/NZW mice treated with long-term cyclo phosphamide. Arthritis Rheum 1975; 18: 265–72
   PubMedGoogle Scholar
• Walker S E, Hewett J E. Responses to T-cell and B-cell mitogens in autoimmune Palmerston North and NZB/NZW mice. Clin Immunol Immunopathol 1984; 30: 469–78
   PubMedGoogle Scholar
• Walker S E, Gray R H, Fulton M, Wigley R D, Schnitzer B. Palmerston North Mice, a new animal model of systemic lupus erythematosus. J Lab Clin Med 1978; 92: 932–45
   PubMed Web of Science ®Google Scholar
• Snedecor G W, Cochran W G. Statistical Methoh Sixth edition. Iowa State University Press, Ames, IA 1967
   Google Scholar
• Walker S E, Anver M R. Accelerated appearance of neoplasms in female NZB/NZW mice treated with high-dose cyclophos phamide. Arthritis Rheum 1979; 22: 1338–43
   PubMedGoogle Scholar
• Melez K A, Boegel W A, Steinberg A D. Therapeutic studies in New Zealand mice. VII. Successful androgen treatment of NZB/NZW F1 females of different ages. Arthritis Rheum 1980; 23: 41–7
   PubMedGoogle Scholar
• Hulka J F, Lieberman M W. Effect of synthetic progestational agents on allograft rejection and circulating antibody production. Endocrinology 1965; 77: 897–901
   PubMedGoogle Scholar
• Vecchi A, Tagliabue A, Mantovani A, Anaclerio A, Barale C, Spreafico F. Steroid contraceptive agents and immunological reactivity in experimental animals. Biomedicine (Paris) 1976; 24: 231–7
   PubMedGoogle Scholar
• Rojo J M, Portoles M P, Portoles A. Immune responses and lymphocyte mitogenic activation in mice under oral contraceptive treatment. J Reprod lmmunol 1980; 2: 29–35
   Google Scholar
• Rojo J M, Portoles M P. Lymphoid-organ variations and blas- togenic responses of splenocytes in estrogen-progestogen treated virgin and multiparous mice. Int J Cls in Pharmacol Ther Toxocol 1982; 20: 139–41
   PubMedGoogle Scholar
• Verheul H AM, Stimson W H, Den Hollander F C, Schuurs A HWM. The effects of nandrolone, testosterone and their decanoate esters on murine lupus. Clin Exp Immunol 1981; 44: 11–7
   PubMedGoogle Scholar
• Murad F, Haynes R C, Jr. Estrogens and progestins. The pharmacological Basis of Therapeutics. Sixth edition, A G Gilman, L S Goodman, A Gilman. Macmillan Publishing Co, New York 1980; 736–44
   Google Scholar
• Pearce P T, Khalid B AK, Funder J W. Progesterone receptors in rat thymus. Endocrinology 1983; 113: 1287–91
   PubMedGoogle Scholar
• Fabris N, Piantanelli L, Muzzioli M. Differential effect of pregnancy or gestagens on humoral and cell-mediated immunity. Clin Exp Immunol 1977; 28: 306–14
   PubMedGoogle Scholar
• Marotti T, Sirotkovic M, Pavelic J, Gabrilovac J, Pavelic K. In vivo effect of progesterone and estrogen on thymus mass and T-cell functions in female mice. Horm Metah Res 1984; 16: 201–3
   PubMedGoogle Scholar
• Gupta C, Bullock L P, Bardin C W. Further studies on the androgenic, anti-androgenic, and synandrogenic actions of progestins. Endocrinology 1978; 102: 736–44
   PubMedGoogle Scholar
• Bullock L P, Bardin C W, Sherman M R. Androgenic. Antiandrogenic, and synandrogenic actions of progestins: Role of steric and allosteric interactions with androgen receptors. Endocrinology 1978; 103: 1768–82
   PubMedGoogle Scholar
• Gardner W U. Estrogens in carcinogenesis. Arch Pathol 1939; 27: 138–70
   Google Scholar
• Noble R L, Hochachka B C, King D. Spontaneous and es trogen-produced tumors in Nb rats and their behavior after transplantation. Cancer Res 1975; 35: 766–80
   PubMed Web of Science ®Google Scholar
• Tougard C, Tixier-Vidal A. Lactotropes and Gonadotropes. The Physiology qf Reproduction, E Knobil, J D Neill. Raven Press, New York 1988; 1305–33
   Google Scholar
• Buckley A R, Putnam C W, Russell D H. Prolactin as a mammalian mitogen and tumor promoter. Adv Enzyme Regul 1988; 37: 371–91
   Google Scholar
• Ly Y. Prolactin stimulates transcription of growth-related genes in Nb2 T lymphoma cells. Mol Cell Endocrinol 1990; 68: 21–8
   PubMedGoogle Scholar
• Selye H. On the toxicity of oestrogens with special reference to diethylstilboestrol. Canada Med Assoc J 1939; 41: 48–9
   PubMedGoogle Scholar
• Burrows H, Kennaway N M. On some effects produced by applying oestrin to the skin of mice. Am J Cancer 1934; 20: 48–57
   Google Scholar
• Melez K A, Reeves J P, Steinberg A D. Modification of murine lupus by sex hormones. Ann Immunol (Paris) 1978; 129C: 707–14
   Google Scholar