5
Views
8
CrossRef citations to date
0
Altmetric
Original Article

The 65 KD Heat Shock Protein: A Key Molecule Mediating the Development of Autoimmune Arthritis?

&
Pages 83-88 | Received 13 Jun 1990, Accepted 12 Sep 1990, Published online: 07 Jul 2009

References

  • Lindquist S. The heat-shock response. Ann Rev Biochem 1986; 55: 1151–91
  • Duboris P. Heat-shock proteins and immunity. Res Immunol 1989; 140: 653–59
  • Young R A, Elliott T L. Stress proteins, infection, and immune surveillance. Cell 1989; 59: 5–8
  • Hurst N P. Stress (heat shock) proteins and rheumatic disease, new advance or just another band wagon. Rheum Int 1990; 9: 271–76
  • Winrow V, McLean L, Morris C J, Black D R. The heat shock protein response and its role in inflammatory disease. Ann Rheum Dis 1990; 49: 128–32
  • Kaufmann S HE. Heat Shock Protein and the Immune Response. Immunol Today 1990; 11: 129–36
  • Vanbuskirk A, Crump L C, Margoliash E, Pierce S K. A peptide binding protein having a role in antigen mesentation is a member of the HSP7O heat shock family. J Exp Med 1989; 170: 1799–1809
  • Jindal S, Dudani C B, Singh B, Harley R S, Gupta R S. Primary structure of a human mitochondrial protein homologous to the bacteria and plant chaperonins and to the 65-kilodalton mycobacterial antigen. Mol Cell Biol 1989; 9: 2279–83
  • Gaston J SH, Life P F, Bailey L C, Bacon P A. In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients. J Immunol 1989; 143: 02494–2500
  • Van Eden W, Thole J ER, Van der Zee R, Noordzij A, Van Embden J DA, Hensen E J, Cohen I R. Cloning of the myco bacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 1988; 331: 171–73
  • Elias D, Markovits D, Reshef T, van der Zee R, Cohen I R. Induction and therapy of autoimmune diabetes in the non- obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. Proc Natl Acad Sci USA 1990; 87: 1576–80
  • Yang X -D, Gasser J, Riniker B, Feige U. Treatment of adjuvant arthritis in rats: vaccination potential of a synthetic nonapeptide from the 65 kDa heat shock protein of mycobacteria. J Autoimmunol 1990 1989; 3: 11–23
  • Yang X -D, Gasser J, Feige U. Prevention of adjuvant arthritis in rats by a nonapeptide from a mycobacterial heat-shock protein. Clin Exp Immunol 1990; 81: 189–94
  • Yang X -D, Gasser J, Feige U. Epitope-specific intervention in adjuvant arthritis: the role of a nonapeptide of the 65 kilodalton mycobacterial heat shock protein, Submitted
  • Stoerk H D, Bielinksi T C, Budzilovich T. Chronic polyarthritis in rats injected with spleen in ajduvants. (abstract). Am J Pathol 1954; 30: 616
  • Pearson C M. Development of arthritis, periarthrtis and periostitis in rats given adjuvants. Proc Soc Exp Biol Med 1956; 91: 95–101
  • Pearson C M. Experimental models in rheumatoid disease. Arthritis Rheum 1964; 7: 80–86
  • Van Eden W, Holoshitz J, Cohen I R. Antigenic mimicry between mycobactena and cartilage proteoglycans: the model of adjuvant arthritis. Concepts Immunopathol 1987; 4: 144–70
  • Kohashi O, Pearson C M, Beck F WJ, Narita T, Kotani S. Arthritogenicity in rats of cell walls from several streptococci, staphylococci and other bacteria. Proc Soc Exp Biol Med 1976; 27: 311–19
  • Chang Y -H, Pearson C M, Chedid L. Adjuvant polyarthritis. V. Induction by n-acetylmuramyl-L-alany-D-isoglutamine the smallest peptide subunit of bacterial peptidoglycan. J Exp Med 1981; 153: 1021–26
  • Pearson C M, Wood F D. Mycobacteria wax D subfractions in induction of adjuvant induced arthritis. Int Arch Allergy 1963; 35: 456–62
  • Chang Y -H, Pearson C H, Abe C. Adjuvant polyarthritis IV. induction by a synthetic adjuvant: immunologic, histopathologic, and other studies. Arthritis Rheum 1980; 23: 62–71
  • Whitehouse M W, Orr K J, Beck F WJ, Pearson C M. Freund's adjuvants: relationship of arthritogenicity and adjuvanticity in rats to vehicle composition. Immunology 1974; 27: 311–30
  • Barnes P F, Mehra V, Hirschfield G R, Fong S -J, Abou-Zeid C, Rook G AW, Hunter S W, Brennan P J, Modlin R L. Characterization of T cell antigens associated with the cell wall protein-peptidoglycan complex of Mycobacterium ruberculosis. J Immunol 1989; 143: 2656–62
  • Berry H, Willoughby D A, Giroud J P. Evidence of an endogenous antigen in the adjuvant arthritic rats. J Path 1973; 111: 229–38
  • Koga T, Wand-Wuerttenberger A, DeBruyn J, Munk M E, Schoel B, Kaufmann S HE. T cells against a bacterial heat shock protein recognize stressed macrophages. Science 1989; 245: 1112–15
  • Karlsson-Parra A, Soderstrom K, Ivanyi F J, Kiessling R, Klareskog L. Presence of Human 65 kD Heat Sock Protein in Inflamed Joints and Subcutaneous Nodules of RA Patients. Scand J Immunol 1990; 31: 283–88
  • Klareskog L. What can we learn about rheumatoid arthritis from animal models. Spring Sem Immunopathol 1989; 11: 315–33
  • Munk M E, Schoel B, Modrow S, Karr R W, Young R A, Kaufmann S HE. T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein. J Immunol 1989; 143: 2844–49
  • Young D B, Ivanyi J, Cox J H, Lamb J R. The 65kDa antigen of mycobacteria- a common bacterial protein. Immunol Today 1987; 8: 215–19
  • Shoenfeld Y, Isenberg D A. Mycobacteria and autoimmunity. Immunol Today 1988; 9: 178–82
  • Tourisu M, Miyahara T, Shinohara N, Ohsato K, Sonozaki H A. A new side-effect of BCG immunotherapy; BCG-induced arthritis in man. Cancer Immunol Immunother 1978; 5: 77–83
  • Zwillich S H, Lipsky P E. Molecular mimicry in the pathogenesis of rheumatic diseases. Rheumatic Disease Clinics of North America 1987; 13: 339–52
  • McCusker C T, Singal D P. Molecular Relationships between the class II HLA antigens and susceptibility to rheumatoid arthritis. J Rheum 1988; 15: 1050–53
  • Van Eden W. Heat-shock proteins in autoimmane arthritis: a critical contribution based on the adjuvant arthritis model. APMIS 1990; 98: 383–94
  • van Eden W, Hogervorst E JM, van der Zee R, van Embden J DA, Cohen I R. A cartilage-mimicking T-cell epitope on a 65K mycobacterial heat-shock protein: adjuvant arthritis as a model for human rheumatoid arthritis. Current Topics Microbiol Immunol 1989; 145: 27–43
  • Gaston J SH, Life P F, Jenner P J, Colston M J, Bacon P A. Recognition of a mycobacteria-specific epitope in the 65-kD heat-shock protein by synovial fluid-derived T cell clones. J Exp Med 1990; 171: 831–41
  • Billingham M EJ, Carney S, Butter R, Colston M J. A mycobacterial 65-kDa heat shock protein induces antigen-specific supression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 1990; 171: 339–44
  • Van Den Broek M F, Hogervorst E JM, Bruggen M CJ, Van Eden W, Van der Zee R, Van Den Berg W B. Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein. J Exp Med 1989; 170: 449–66
  • Swanborg R H. Antigen-induced inhibition of experimental allergic encephalomyelitis. III. Localization of an inhibitory site distinct from the major encephalitogenic determinant of myelin basic protein. J Immunol 1975; 114: 191–94
  • Higgins P J, Weiner H O. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments. J Immunol 1988; 140: 440–45
  • Cohen I R, Atlan H. Network regulation of autoimmunity: an automaton model. J Autoimmunity 1989; 2: 613–25
  • Vandenbark A A, Hashim G A, Celnik B, Galang A, Li X, Heber-Katz L, Offner H. Determinants of human basic myelin protein that induce encephalitogenic T cells in Lewis rats. J Immunol 1989; 143: 3512–16
  • Cohen I R. T cell vaccination and suppression of autoimmune disease. Progress in Immunology VII, F. Melchers, et al. Springer-Verlag, Berlin 1989; 867–74

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.