3
Views
1
CrossRef citations to date
0
Altmetric
Original Article

The Bgl II Rflp Associated with Type 1 Diabetes in Dr3-Positive Subjects is Not Due to a Dqa1 Promoter Region Polymorphism

, , , , , & show all
Pages 123-125 | Received 13 Aug 1993, Published online: 07 Jul 2009

References

  • Cavan DA, Jacobs KH, Penny MA, Kelly MA, Mijovic C, Jenkins D. Both DQA1 and DQB1 genes are implicated in HLA-associated protection from Type 1 (insulin-dependent) diabetes in a British Caucasian population. Diabetologia 1993; 36: 252–257
  • Cavan DA, Jenkins D, Penny M, Jacobs KH, Mijovic C, Fletcher J. DR7 haplotype analysis supports DQw2 as a susceptibility allele for Type I (insulin-dependent) diabetes mellitus. Diabetes 1991; 40: 141 A, Suppl 1
  • Nishimito H, Kikutani H, Yamamura K, Kishimoto T. Prevention of autoimmune insulitis by expression of I-E molecules in NOD mice. Nature 1987; 328: 432–434
  • Kimura A, Sazasuki T. Polymorphism in the 5' flanking region of the HLA-DQA1 gene and its relation to the DR-DQ haplotype. Proceedings of the Eleventh International Histocompatibility Workshop and Conference., K Tsuji, M Aizawa, T Sasazuki. Oxford Scientific Publications, Oxford 1992; 382–385
  • Andersen CL, Beaty JS, Nettles JW, Seyfried CE, Nepom GT. Nepom BS Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes. J. Exp. Med. 1991; 173: 181–192
  • Carrier C, Mollen N, Ginsberg-Fellner F, Rothman WC, Rubinstein P. A BglII fragment labels a subset of B8, DR3 haplotypes uniquely associated with insulin-dependent diabetes mellitus. Human Immunology 1989; 26: 344–352
  • Ombra MN, del Pozzo G, Perfetto C, MafFei A, Guardiola J. Effect of the A1R-1 locus on the activation of an enhancerless HLA-DQA1 promoter. Immunogenetics 1990; 31: 368–376
  • Wolf E, Spencer KM, Cudworth AG. The genetic susceptibility to Type 1 (insulin-dependent) diabetes: analysis of the HLA-DR association. Diabetologia 1983; 24: 224–230
  • Rubinstein P. HLA and IDDM: facts and speculations on the disease gene and its mode of inheritance. Human Immunol 1991; 30: 270–277

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.