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Original Article

Some Anti-thyroperoxidase Antibodies Positive Sera Give a pANCA Pattern on Ethanol-fixed Human Neutrophils: Cross-Reactivity or False Positives?

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Pages 117-122 | Received 15 Jul 1996, Accepted 15 Jul 1996, Published online: 07 Jul 2009

References

  • Davies D. J., Moran J. E., Nial J. F., Ryan G. B. Segmental necrotizing glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology. Br. Med. J. 1982; 285: 606
  • Falk R. J., Jennette J. C. Anti-neutrophil cytoplasmic antibodies with specificity for myeloperoxidase in patients with sistemic vasculitis and idiophatic necrotizing and crescentic glomerulonephritis. N. Engl. J. Med. 1988; 318: 1651–1657
  • Goldschmeding R., ten Bokkel Huinink D., Faber N., Tetteroo P. A. T., Vroom T. M., Hack C. E., van dem Borne A. E. G.K. Identification of the “ANCA antigen” as a novel myeloid Iysosomal serine protease. APMIS 1989; 97: 46
  • Kao R. G., Wehner N. C., Skubitz K. M., Gray B. H., Hoidal J. R. Proteinase 3: a distinct human polymorphonuclear leucocyte proteinase that produces enphysema in hamsters. J. Clin. Invest. 1988; 82: 1963–1973
  • Goldschmeding R., Cohen, Tervaert J. W., Gans R. O., Dolman K. M., van der Ende M. E., Kuzinga M. C., Kallemberg C. G., van dem Borne A. E. Different immunological specificities and disease associations of cANCA and pANCA. Neth. J. Med. 1990; 36: 114–116
  • Halbwachs-Mecarelli L., Nusbaum P., Noel L. H., Reumaux D., Erlinger S., Grunfeld J. P., Lesaure P. Antineutrophil cytoplasmic antibodies (ANCA) directed against cathepsin G in ulcerative colitis, Crohn's disease and primary sclerosing cholangitis. Clin. Exp. Immunol. 1992; 90: 79–84
  • Nassberger L., Ljungh A., Schumacher G., Kollberg B. β-glucuronidase antibodies in ulcerative colitis. Lancet 1992; 340: 314–375
  • Dolmann K. M., Damsma I., Tool A. T. J., Sonnenberg A, van dem Borne A. E., Goldschmeding R. A novel specificity of anticytoplasmic autoantihodies directed against eosinophil peroxidase. Clin. Exp. Immunol. 1993; 92: 58–64
  • Savage C. O. S., Lockwood C. M. Antineutrophil antibodies in vasculitis. Adn. Nephrol. 1990; 19: 73–92
  • Jennette J. C., Falk R. J. Diagnostic classification of antineutrophil cytoplasmic autoantibody associated vasculitides. Am. J. Kidney Dis. 1991; 18: 184–187
  • Hoffmann G. S., Kerr G. S., Leavitt R. Y., Hallahan C. W., Lebouics R. S., Travis W. D., Rottem M., Fauci A. S. Wegener's granulomatosis: an analysis of 158 patients. Ann. Intern. Med. 1992; 116: 488–498
  • Roitt L. M., Ling N. R., Doniach B., Couchman K. G. The cytoplasmic auto-antigen of the human thyroid. Immunological and biochemical characteristics. Immunolgy 1964; 7: 315–393
  • Hamada N., Portmann L., De Groot L. J. Characterization and isolation of thyroid microsomal antigen. J. Clin. Invest. 1987; 19: 819–825
  • Mariotti S., Anelli S., Ruf J., et al. Comparison of serum thyroid microsomal and thyroid peroxidase autoantibodies in thyroid diseases. J. Clin. Endocrinol. Metab. 1987; 65: 981–993
  • Kimura S., Ikeda-Saito M. Human myeloperoxidase and thyroid peroxidase, two enzymes with separate and distinct physiological functions are evolutionary related members of same gene family. Proteins 1988; 3: 113–120
  • Haapala A. M., Soppi E., Hyoty H., Mustonen J., Pasternack A. Cross-reactivity between antibodies to thyroid microsomal antigens and myeloperoxidase. Lancet 1991; 337: 803
  • Wiik A. Delineation of a standard procedure for indirect immunofluorescence detection of ANCA. Acta. Pathol. Microbiol. Immunol. Scand. 1989; 91: 12–13
  • Nauseef W. M., Root R. K., Malech H. L. Biochemical and immunologic analysis of hereditary myeloperoxidase deficiency. J. Clin. Invest. 1983; 71: 1297–1307
  • Parry M. F., Root R. K., Metcalf J. A., Delaney K. K., Kaplow L. S., Richard W. J. Myeloperoxidase deficiency. Prevalence and clinical significance. Ann. Intern. Med. 1981; 95: 293–301
  • Salmon S. E., Cline M. J., Schultz J., Lehrer R. L. Myeloperoxidase deficiency. Immunologic study of a genetic leukocyte defect. N. Engl. J. Med. 1970; 282: 250–253
  • Falk R. J., Becker R., Terrell R., Jennette J. C. Anti-myeloperoxidase autoantibodies react with native but not denatured myeloperoxidase. Clin. Exp. Immunol. 1992; 89: 274–278
  • Nauseef W. M. Aberrant restriction endonuclease digests of DNA from subjects with hereditary myeloperoxidase deficiency. Blood 1989; 73: 290–295
  • Chang L., Savige J. Studies to demonstrate inhibition of functional activity of neutrophil lysosomal enzymes with ANCA. Adv. Exp. Med. Biol. 1993; 336: 97–100
  • Mayet W. J., Meyer zum Buschenfelde K. H. Antibodies to proteinase 3 increase adhesion of neutrophils to human endothelial cells. Clin. Exp. Immunol. 1993; 94: 440

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