Immunotoxicity of zearalenone in Balb/c mice in a high subchronic dosing study counteracted by Raphanus sativus extract

References

• Fink-Gremmels, J. Mycotoxins: their implications for human and animal health. Vet. Q. 1999, 21, 115–120.
   PubMed Web of Science ®Google Scholar
• The Commission of the European Communities. Commission recommendation of 17 August 2006: on the presence of deoxynivalenol, zearalenone, ochratoxin A, T-2 and HT-2 and fumonisin in products intended for animal feeding. Off. J. European Union 2006, L229, 7–9.
   Google Scholar
• Abbès, S., Ouanes, Z., ben Salah-Abbès, J., Houas, Z., Oueslati, R., Bacha, H., Othman, O. The protective effect of hydrated sodium calcium aluminosilicate against haematological, biochemical and pathological changes induced by Zearalenone in mice. Toxicon 2006, 47, 567–574.
   PubMed Web of Science ®Google Scholar
• Abbès, S., Salah-Abbès, J.B., Ouanes, Z., Houas, Z., Othman, O., Bacha, H., Abdel-Wahhab, M.A., Oueslati, R. Preventive role of phyllosilicate clay on the Immunological and Biochemical toxicity of zearalenone in Balb/c mice. Int. Immunopharmacol. 2006, 6, 1251–1258.
   PubMed Web of Science ®Google Scholar
• Ben Salah-Abbès J., Abbès, S., Ouanes, Z., Houas, Z., Abdel-Wahhab, M.A., Bacha, H., Oueslati, R. Tunisian radish extract (Raphanus sativus) ameliorates the antioxidant status and mediates the oxidative stress of Zeralenone in Balb/c mice. J. Appl. Toxicol. 2008a, 28, 6–14.
   PubMed Web of Science ®Google Scholar
• Bondy, G.S., Pestka, J.J. Immunomodulation by fungal toxins. J. Toxicol. Environ. Health. B. Crit. Rev. 2000, 3, 109–143.
   PubMed Web of Science ®Google Scholar
• Marin, M.L., Murtha, J., Dong, W., Pestka, J.J. Effects of mycotoxins on cytokine production and proliferation in EL-4 thymoma cells. J. Toxicol. Environ. Health 1996, 48, 379–396.
   PubMed Web of Science ®Google Scholar
• Newman, D.J., Cragg, G.M., Snader, K.M. Natural products as sources of new drugs over the period 1981-2002. J. Nat. Prod. 2003, 66, 1022–1037.
   PubMed Web of Science ®Google Scholar
• Lee, K.H. Current developments in the discovery and design of new drug candidates from plant natural product leads. J. Nat. Prod. 2004, 67, 273–283.
   PubMed Web of Science ®Google Scholar
• Kapoor, L.D. Handbook of Ayurvedic medicinal plants. 1990;Boca Raton CRC Press.
   Google Scholar
• Steinkellner, H., Rabot, S., Freywald, C., Nobis, E., Scharf, G., Chabicovsky, M., Knasmüller, S., Kassie, F. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutat. Res. 2001, 480–481, 285–297.
   Google Scholar
• Posner, G.H., Cho, C.G., Green, J.V., Zhang, Y., Talalay, P. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes. J. Med. Chem. 1994, 37, 170–176.
   PubMed Web of Science ®Google Scholar
• Ben Salah-Abbès, J., Abbès, S, Mossad, A. Abdel-Wahhab, Ridha Oueslati. In vitro free-radical scavenging, antiplorifilative and anti-zearalenone cytotoxicity effects of 4-(Methylthio)-3-butenyl isothiocyanate from (Tunisian) Raphanus sativus. In press Journal of Pharmacy and pharmacology 2009d.
   Google Scholar
• Mithen, R.F., Dekker, M., Verkerk, R., Rabot, S., Johnson, I.T. The nutritional significance, biosynthesis and bioavailability of glucosinolates in human foods. J. Sci. Fd. Agric. 2000, 80, 967–984.
   Web of Science ®Google Scholar
• Manson, M.M., Ball, H.W., Barrett, M.C., Clark, H.L., Judah, D.J., Williamson, G., Neal, G.E. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism. Carcinogenesis 1997, 18, 1729–1738.
   PubMed Web of Science ®Google Scholar
• Ben Salah-Abbès J., Abbès, S., Ouanes, Z., Abdel-Wahhab, M.A., Bacha, H., Oueslati, R. Isothiocyanate from the Tunisian radish (Raphanus sativus) prevents genotoxicity of Zearalenone in vivo and in vitro. Mutat. Res. 2009, 677, 59–65.
   PubMed Web of Science ®Google Scholar
• Cuénod, A. Flore de la Tunisie: cryptogames vasculaires, gymnospermes et monocotylédones. Office de l’expérimentation de la vulgarisation agricoles de Tunisie, (1954) p 233–248. 2ème édition Elfarabi Press, Tunis.
   Google Scholar
• Wang, L., Burhenne, K., Kristensen, B.K., Rasmussen, S.K. Purification and cloning of a Chinese red radish peroxidase that metabolise pelargonidin and forms a gene family in Brassicaceae. Gene 2004, 343, 323–335.
   PubMed Web of Science ®Google Scholar
• Ben Salah-Abbès J, Abbès, S, Houas, Z, Abdel-Wahhab, M.A., Oueslati R. Zearalenone induces immunotoxicity in mice: possible protective effects of Radish Extract (Raphanus Sativus). J. Pharma. Pharmacol. 2008b, 60, 1–10.
   Google Scholar
• Ben Salah-Abbès J., Abbès, S., Abdel-Wahhab, M.A., Oueslati, R. Raphanus sativus extract protects against Zearalenone induced reproductive toxicity, oxidative stress and mutagenic alterations in male Balb/c mice. Toxicon 2009, 53, 525–533.
   PubMed Web of Science ®Google Scholar
• Salah-Abbès, J.B., Abbès, S., Haous, Z., Oueslati, R. Raphanus sativus extract prevents and ameliorates zearalenone-induced peroxidative hepatic damage in Balb/c mice. J. Pharm. Pharmacol. 2009, 61, 1545–1554.
   PubMed Web of Science ®Google Scholar
• Howell, M.V., Taylor, P.W. Determination of aflatoxins, ochratoxin a, and zearalenone in mixed feeds, with detection by thin layer chromatography or high performance liquid chromatography. J. Assoc. Off. Anal. Chem. 1981, 64, 1356–1363.
   PubMedGoogle Scholar
• Manolescu, N, Barza, A, Caprarin, H, Sinchievici, B. Ghid de Hematologie a animalelor in crestere intensiva. 2nd ed. Ed. Ceres, 1978;Bucharest, Romania.
   Google Scholar
• NTP. Carcinogenicity bioassay of zearalenone in F344/N rats and F6C3F1 mice. National Toxicology Program Technical Reports Series 235. National Toxicology Program. Research Triangle Park, NC, 1982;USA.
   Google Scholar
• Pfohl-Leszkowicz, A., Chekir-Ghedira, L., Bacha, H. Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues. Carcinogenesis 1995, 16, 2315–2320.
   PubMed Web of Science ®Google Scholar
• Ahamed, S., Foster, J.S., Bukovsky, A., Wimalasena, J. Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Mol. Carcinog. 2001, 30, 88–98.
   PubMed Web of Science ®Google Scholar
• Yu, Z., Zhang, L., Wu, D., Liu, F. Anti-apoptotic action of zeara-lenone in MCF-7 cells. Ecotoxicol. Environ. Saf. 2005, 62, 441–446.
   PubMed Web of Science ®Google Scholar
• FAO Worldwide regulations for mycotoxins in food and feed in 2003. FAO Food and Nutrition paper No. 81. Food and Agriculture Organization of the United Nations, Rome, 2004;Italy.
   Google Scholar
• Ghali, R, Hmaissia-khlifa, K, Ghorbel, H, Maaroufi, K, Hedili, A. Incidence of aflatoxins, ochratoxin A and zearalenone in tunisian foods. Food Control 2008, 19, 921–924.
   Web of Science ®Google Scholar
• Zourgui, L., Golli, E.E., Bouaziz, C., Bacha, H., Hassen, W. Cactus (Opuntia ficus-indica) cladodes prevent oxidative damage induced by the mycotoxin zearalenone in Balb/C mice. Food Chem. Toxicol. 2008, 46, 1817–1824.
   PubMed Web of Science ®Google Scholar
• Conková, E., Laciaková, A., Pástorová, B., Seidel, H., Kovác, G. The effect of zearalenone on some enzymatic parameters in rabbits. Toxicol. Lett. 2001, 121, 145–149.
   PubMed Web of Science ®Google Scholar
• Kaneko, J.J. Clinical Chemistry of Domestic animals, (4th Ed.), Academic Press, San Diego, 1989;CA.
   Google Scholar
• Harvey, R.B., Phillips, T.D., Ellis, J.A., Kubena, L.F., Huff, W.E., Petersen, H.D. Effects on aflatoxin M1 residues in milk by addition of hydrated sodium calcium aluminosilicate to aflatoxin-contaminated diets of dairy cows. Am. J. Vet. Res. 1991, 52, 1556–1559.
   PubMed Web of Science ®Google Scholar
• Fernández, A., Verde, M.T., Gomez, J., Gascon, M., Ramos, J.J. Changes in the prothrombin time, haematology and serum proteins during experimental aflatoxicosis in hens and broiler chickens. Res. Vet. Sci. 1995, 58, 119–122.
   PubMed Web of Science ®Google Scholar
• Joens, L.A., Pier, A.C., Cutlip, R.C. Effects of aflatoxin consumption on the clinical course of swine dysentery. Am. J. Vet. Res. 1981, 42, 1170–1172.
   PubMed Web of Science ®Google Scholar
• Harvey, RB, Kubena, LF, Elissade, MH, Corrier, DE, Phillips, TD. Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine J. Vet. Diagn. Invest. 1995, 7, 374–379.
   PubMed Web of Science ®Google Scholar
• de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C.G., de Vries, J.E. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 1991, 174, 1209–1220.
   PubMed Web of Science ®Google Scholar
• Moon, E.Y., Rhee, D.K., Pyo, S. In vitro suppressive effect of aflatoxin B1 on murine peritoneal macrophage functions. Toxicology 1999, 133, 171–179.
   PubMed Web of Science ®Google Scholar
• Abbès, S., Ben Salah-Abbès J., Hetta, M.M., Ibrahim, M., Abdel-Wahhab, M.A., Bacha, H., Oueslati, R. Efficacy of Tunisian montmorillonite for in vitro aflatoxin binding and in vivo amelioration of physiological alterations Appl. Clay. Science. 2008, 42, 151–157.
   Web of Science ®Google Scholar
• Guerra, J.A., Molina, M.F., Abad, M.J., Villar, A.M., Paulina, B. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum. Int. Immunopharmacol. 2006, 6, 1723–1728.
   PubMed Web of Science ®Google Scholar