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Immunopharmacology and Immunotoxicology Volume 15, 1993 - Issue 5
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Research Article

Inmjnostimjlant Activity of A Novel Lipopeptide and Its Protective Action Against Leishmnia Donovani

A. Puri Division of Biochemistry, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
S. Y. Rizvi Division of Biopolymers, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
W. Haq Division of Biopolymers, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
P. Y Guru Division of Parasitology, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
B. Kundu Division of Biopolymers, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
R. P. Saxena Division of Biochemistry, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
R. Shukla Division of Pharmacology, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
,
K. B. Mathur Division of Biopolymers, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
&
K. C. Saxena Division of Biochemistry, Central Drug Research Institute, Post Box No. 173, Lucknow, 226 001, INDIA
 show all
Pages 539-556 | Published online: 28 Sep 2008

References

  • Migliore-Samour D., Bouchaudon J., Floch F., Zerial A., Nimet L., Werner G. H., Jolles P. A short lipo-peptide representative of a new family of inrmunological adjuvants devoid of sugar. Life Sci. 1980; 26: 883
  • Migliore-Samour D., Bouchaudon J., Floch F., Zerial A., Nimet L., Werner G. H., Jolles P. Inrnunostimulating and adjuvant properties of a short lipopeptide. C.R. Hebd Seances Acad. Sci. Ser. D. 1979; 289(5)473
  • Werner G. H., Floch F., Bouchaudon J., Zerial A., Migliore-Samour, Jolles P. Low molecular weight synthetic lipo-peptides: a new class of irrmunopotentiating substances. Dev. Inmunol. 1982; 17: 645, (Current Concepts Hum. Inmunol. Cancer Inmunomodulation)
  • Herrmi K., Takano H., Okada S., Nakaguchi U., Kitauro Y., Hashimoto M. Total synthesis of FK-156 isolated from a streptomyces as an itimunostimulating peptide. J. American Chem. Soc 1981; 103: 7026
  • Kitaura Y., Nakaguchi O., Takeno H., Okada S., Yonishi S., Hernni K., Morisenoh H., Mine Y., Hashimoto M. N -(γY -D-Glutamyl)-meso-2(L),21 (D)-diaminopimelic acid as the minimal prerequisite structure of FK-156: Its acyl derivatives with potent irrmunostimulating activity. J. Med. Chem. 1982; 25: 335
  • Floch F., Bouchaudon J., Fizames C., Zerial A., Dutrue-Rosset G., Werner G. H. Lauroyl tetrapeptide (RP-40639) and related lipopeptides: A novel class of synthetic irnnuno-modulating agents. Drug of Future 1984; 9: 763
  • Izumi S., Nakahara K., Gotoch T., Hashimoto S., Kino T., Okumura M., Aoki H., Imanaka H. Antitumor effects of novel imnunoactive peptides, LFK-156 and its synthetic derivatives. J. Antibiotics 1983; 36: 556
  • Kotani S., Kinoshita F., Morisaki I., Shimono T., Okunaga T., Takada H., Tsujimoto M., Watanabe Y., Kato K., Shiba T., Kusurroto S., Okada S. Itimunoadjuvant activities of synthetic 6–0-acyl-N-acetylmuramyl-L-alanyl-D-isoglu-tamine with special reference to the effect of its administration with liposomes. Biken J. 1977; 20: 95
  • Jerne N. K., Nordin A. A. Plaque formation in agar by single antibody producing cell. Science 1963; 140: 405
  • Saiki I., Tanio Y., Waki Yama M., Uemiya M., Kabayashi S., Fukuda T., Yukamasa H., Yamamura Y., Azuma I. Adjuvant activity of Quinonyl-N-acetyl muramyl dipeptides in mice and guinea pigs. Infect. Inmun. 1981; 31: 114
  • Saxena K. C., Puri Anju., Sumati Saxena R., Saxena R. P.J. Macrophage migration as an index of imnune status. Inmunol. Invest. 1991; 20: 431
  • Leijh P. C.J., Vanden Barselaar M. T., Van Furth R. J. Kinetics of phagocytosis and intracellular killing of Candida albicans by human granulocytes and monocytes. Infect. Inmun. 1977; 17: 313
  • Chedid L. A., Parant M. A., Audibert F. M., Riveau G. J., Parant F. J., Lederer E., Choay J. P., Lefrancier P. L. Biological activity of a new synthetic muramyl peptide adjuvant devoid of pyrogenicity. Infect. Inmun. 1982; 35: 417
  • Stauber L. A. Host resistance to the Khartoum strain of Leishmania donovani. Rice Institute Pam. 1958; 45: 80

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