Dietary Quercetin, Immune Functions and Colonic Carcinogenesis in Rats

References

• Brown J. P. A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds. Mutation Res. 1980; 75: 243–277
   PubMed Web of Science ®Google Scholar
• Hertog M. G., Hollman P. C., Katan M. B., Kromhout D. Intake of ptentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr. Cancer 1993; 20: 21–29
   PubMed Web of Science ®Google Scholar
• Hertog M. G. L., Hollman P. C. H., Katan M. B. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J. Agric. Food Chem. 1992; 40: 2379–2383
   Web of Science ®Google Scholar
• Bjeldans L. F., Chang G. W. Mutagenic activity of quercetin and related compounds. Science 1977; 197: 577–578
   PubMed Web of Science ®Google Scholar
• Pamukcu A. M., Yalciner S., Hatcher J. F., Bryan G. T. Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum). Cancer Res. 1980; 40: 3468–3472
   PubMed Web of Science ®Google Scholar
• Dunnick J. K., Hailey J. Toxicity and carcinogenicity studies of quercetin a natural component of foods. Fund. Applied Toxicol. 1992; 19: 423–431
   PubMedGoogle Scholar
• Akagi K., Hirose M., Hoshiya T., Mizoguchi Y., Ito N., Shirai T. Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model. Cancer Lett. 1995; 94: 113–121
   PubMed Web of Science ®Google Scholar
• Pereira M A, Grubbs C. J., Barnes L. H., Li H., Olson G. R., Eto I., Juliana M., Whitaker L. M., Kelloff G. J., Steele V. E., Lubet R. A. Effects of phytochemicals, curcumin and quercetin, upon azoxymethane- induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats. Carcinogenesis 1996; 17: 1305–1311
   PubMed Web of Science ®Google Scholar
• Kato R., Nakadate T., Yamamoto S., Sugimura T. Inhibition of 12-0-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipooxygenase inhibition. Carcinogenesis 1983; 4: 1301–1305
   PubMed Web of Science ®Google Scholar
• Khan W. A., Wang Z. Y., Athar M., Bickers D. R., Mukhtar H. Inhibition of the skin tumorigenicity of (±)-7β, 8α-dihydroxy-9α,10α-epoxy-7, 8,9,10-tetrahydrobenzo[a]pyrene by tannic acid, green tea polyphenols and quercetin in Sencar mice. Cancer Lett. 1988; 42: 7–12
   PubMed Web of Science ®Google Scholar
• Balasubramanian S., Govindasamy S. Inhibitory effect of dietary flavonol quercetin on 7,12-dimethyl-benz[a]anthracene-induced hamster buccal pouch carcinogenesis. Carcinogenesis 1996; 17: 877–879
   PubMed Web of Science ®Google Scholar
• Elangovan V., Sekar N., Govindasamy S. Chemopreventive potential of dietary bioflavonoids against 20-methycholanthrene-induced tumorigenesis. Cancer Letters 1994; 87: 107–113
   PubMed Web of Science ®Google Scholar
• Verma A. K., Johnson J. A., Gould M. N., Tanner M. A. Inhibition of 7,12-dimethlbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin. Cancer Res. 1988; 48: 5754–5758
   PubMed Web of Science ®Google Scholar
• Deschner E. E., Ruperto J., Wong G., Newmark H. L. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991; 12: 1193–1196
   PubMed Web of Science ®Google Scholar
• Haas A., Heller I., Presek P. Detection of a tyrosine kinase in human sera and blood cells by pp60src antiserum. Biochem. Biophys. Res. Comm. 1986; 135: 426–434
   PubMed Web of Science ®Google Scholar
• Maxwell S. A., Arlinghaus R. B. Serine kinase activity associated with Moloney murine sarcoma virus-124-encoded p37mos. Virology 1985; 143: 321–333
   PubMed Web of Science ®Google Scholar
• Formica J. V., Regelson W. Review of the biology of quercetin and related bioflavonoids. Fd. Chem Toxic. 1995; 33: 1061–1080
   PubMed Web of Science ®Google Scholar
• Lee S. J., Choi J. H., Son K. H., Chang H. W., Kang S. S., Kim H. P. Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring bioflavonoids. Life Sci. 1995; 57: 51–558
   Web of Science ®Google Scholar
• Larocca L. M., Teofili L., Sica S., Piantelli M., Maggiano N., Leone F., Ranelletti F. O. Quercetin inhibits the growth of leukemic progenitors and induces the expression of transforming growth factor-pi in these cells. Blood 1995; 85: 3654–3661
   PubMed Web of Science ®Google Scholar
• Sahu S. C., Washington M. C. Quercetin-induced lipid peroxidation and DNA damage in isolated rat-liver nuclei. Cancer Lett 1991; 58: 75–79
   PubMed Web of Science ®Google Scholar
• Sahu S. C., Washington M. C. Effect of ascorbic acid and curcumin on quercetin-induced nuclear DNA damage, lipid peraxidation and protein degradation. Cancer Lett. 1992; 63: 237–241
   PubMed Web of Science ®Google Scholar
• Middleton E., Kandaswami C. Plant flavonoid modulation of immune and inflammaory cell functions, Human Nutrition-A comprehensive Treatise. Nutrition and Immunology, D. M. Klurfeld. Plenum Press, New York 1993; Vol.8: 239–266
   Google Scholar
• Leung K. H., Ip M. M. Regulation of rat natural killing. II. Inhibition of cytolysis and activation by inhibitors of lipxygenase: Possible role of leukotrienes. Cellular Immunol. 1986; 100: 474–484
   PubMed Web of Science ®Google Scholar
• Steele T., Brahmi Z. Phosphatidylinositol metabolism accompanies early activation events in tumor target cell-stimulated human natural killer cells. Cellular Immunol. 1988; 112: 402–413
   PubMed Web of Science ®Google Scholar
• Exon J. H., Koller L. D., Talcott P A, O'Reilly C. A., Henningsen G. M. Immunotoxicity testing: an economical multiple-assay approach. Fund. Appl. Toxicol. 1986; 7: 387–397
   PubMedGoogle Scholar
• Exon J. H., Mather G. G., Bussiere J. L. Immunotoxicity testing in the rat: an improved multiple assay model. Int. J. Immunopharmacol. 1990; 126: 699–701
   Web of Science ®Google Scholar
• Yamada K., Yoshitake K., Sato M., Ahnen D. H. Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium of the rat. Gastroenterol. 1992; 103: 160–167
   PubMed Web of Science ®Google Scholar
• Foley J., Ton T., Maronpot R., Butterworth B., Goldsworthy T. L. Comparison of proliferating cell nuclear antigen to tritiated thymidine as a marker of proliferating hepatocytes in rats. Environ. Health Perspect. 1993; 101: 199–206
   PubMed Web of Science ®Google Scholar
• Bird R. P. Further investigation of the effect of cholic acid on the induction, growth characteristics and stability of aberrant crypt foci in the rat colon. Cancer Lett. 1995; 88: 210–209
   Web of Science ®Google Scholar
• Ikeda Y., Kawakami K., Sato I., Tajima S., Ito K., Nose T. Effect of cianidanol (KB-53) on the activity of mouse cytotoxic-T-lymphocytes. J. Pharm. Dyn. 1984; 7: 15–20
   PubMedGoogle Scholar
• Veckenstedt A., Guttner J., Beladi I. Synergistic action of quercetin and murine alpha/beta interferon in the treatment of Mengo virus infection in mice. Antiviral Res. 1987; 7: 169–178
   PubMed Web of Science ®Google Scholar
• Yoshimoto T., Furukawa M., Yamamoto S., Horie T., Watanabe-Kohno S. Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase. Biochem. Biophys. Res. Comm. 1983; 116: 612–618
   PubMed Web of Science ®Google Scholar
• Koshihara Y., Neichi T., Murota S., Lao A., Fujimoto Y., Tatsuno T. Selective inhibition of 5-lipoxygenase by natural compounds. FEBS 1983; 158: 41–44
   PubMed Web of Science ®Google Scholar
• Par A., Kiraly T., Magyarlaki T., Kerekes E., Paal M., Javor T. Immunomodualtory effects of cyanidanol in chronic active hepatitis. Int. J. Immunotherapy 1985; 1: 27–33
   Web of Science ®Google Scholar
• Manach C., Morand C., Texier O., Favier M.-L., Agullo G., Demigne C., Regerat F., Remesy C. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J. Nutr 1995; 125: 1911–1922
   PubMed Web of Science ®Google Scholar
• Hollman P., Gaag M., Mengelers M., van Trijp J., de Vries J., Katan M. Absorption and disposition kinetics of the dietary antioxidant quercetin in man. Free Radical Biol. Med. 1996; 21: 703–707
   PubMed Web of Science ®Google Scholar
• Galvez J., Crespo M., Jimenez J., Suarez A., Zarzuelo A. Antidiarrhoeic activity of quercitrin in mice and rats. J. Pharm. Pharmacol. 1993; 45: 157–159
   PubMed Web of Science ®Google Scholar
• Akagi K., Hirose M., Hoshiya T., Mizoguchi Y., Ito N., Shirai T. Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogeneis model. Cancer Lett. 1995; 94: 113–121
   PubMed Web of Science ®Google Scholar
• Wargovich M., Eng V., Newmark H. Inhibition by plant phenols of benzo[a]pyrene-induced nuclear aberrations in mammalian intestinal cells: a rapid in vivo assessment method. Fd. Chem. Toxic 1985; 23: 47–49
   PubMed Web of Science ®Google Scholar