Prediction of Marginal Mass Required for Successful Islet Transplantation

REFERENCES

• Frank A, Deng S, Huang X, . Transplantation for type I diabetes: comparison of vascularized whole-organ pancreas with isolated pancreatic islets. Ann Surg. 2004;240:631–640.
   PubMed Web of Science ®Google Scholar
• Hering BJ, Kandaswamy R, Ansite JD, . Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes. JAMA. 2005;293:830–835.
   PubMed Web of Science ®Google Scholar
• Shapiro AM, Ricordi C, Hering BJ, . International trial of the Edmonton protocol for islet transplantation. New Engl J Med. 2006;355:1318–1330.
   PubMed Web of Science ®Google Scholar
• Hering BJ. Achieving and maintaining insulin independence in human islet transplant recipients. Transplantation. 2005;79:1296–1297.
   PubMed Web of Science ®Google Scholar
• Rickels MR, Schutta MH, Markmann JF, . beta-Cell function following human islet transplantation for type 1 diabetes. Diabetes. 2005;54:100–106.
   PubMed Web of Science ®Google Scholar
• Korsgren O, Nilsson B, Berne C, . Current status of clinical islet transplantation. Transplantation. 2005;79:1289–1293.
   PubMed Web of Science ®Google Scholar
• Weber DJ, McFarland RD, Irony I. Selected Food and Drug Administration review issues for regulation of allogeneic islets of Langerhans as somatic cell therapy. Transplantation. 2002;74:1816–1820.
   PubMed Web of Science ®Google Scholar
• Knazek RA. The human pancreatic islet cell resource consortium. Diabetes Technol Ther. 2002;4:551–552.
   PubMedGoogle Scholar
• Eckhoff DE, Eckstein C, Smyth CA, . Enhanced isolated pancreatic islet recovery and functionality in rats by 17 beta-estradiol treatment of brain death donors. Surgery. 2004;136:336–345.
   PubMed Web of Science ®Google Scholar
• Contreras JL, Eckstein C, Smyth CA, . Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. Diabetes. 2003;52:2935–2942.
   PubMed Web of Science ®Google Scholar
• Bretzel RG, Alejandro R, Hering BJ, . Clinical islet transplantation: guidelines for islet quality control. Transplant Proc. 1994;26:388–392.
   PubMed Web of Science ®Google Scholar
• Paraskevas S, Aikin R, Maysinger D, . Activation and expression of ERK, JNK, and p38 MAP-kinases in isolated islets of Langerhans: implications for cultured islet survival. FEBS Lett. 1999;455:203–208.
   PubMed Web of Science ®Google Scholar
• Paraskevas S, Maysinger D, Wang R, . Cell loss in isolated human islets occurs by apoptosis. Pancreas. 2000;20:270–276.
   PubMed Web of Science ®Google Scholar
• Papas KK, Hering BJ, Guenther L, . Pancreas oxygenation is limited during preservation with the two-layer method. Transplant Proc. 2005;37:3501–3504.
   PubMed Web of Science ®Google Scholar
• Papas KK, Colton CK, Qipo A, . Islet quality assay based on oxygen consumption rate and DNA measurements predicts graft function in mice. Cell Transplant. 2003;12:176.
   Web of Science ®Google Scholar
• Goto M, Holgersson J, Kumagai-Braesch M, . The ADP/ATP ratio: a novel predictive assay for quality assessment of isolated pancreatic islets. Am J Transplant. 2006;6:2483–2487.
   PubMed Web of Science ®Google Scholar
• Fraker C, Timmins MR, Guarino RD, . The use of the BD oxygen biosensor system to assess isolated human islets of Langerhans: oxygen consumption as a potential measure of islet potency. Cell Transplant. 2006;15:745–758.
   Google Scholar
• Ichii H, Inverardi L, Pileggi A, . A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant. 2005;5:1635–1645.
   PubMed Web of Science ®Google Scholar
• Armann B, Hanson MS, Hatch E, . Quantification of basal and stimulated ROS levels as predictors of islet potency and function. Am J Transplant. 2007;7:38–47.
   PubMed Web of Science ®Google Scholar
• Papas KK, Colton CK, Nelson RA, . Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice. Am J Transplant. 2007;7:707–713.
   Google Scholar
• Sweet IR, Gilbert M, Jensen R, . Glucose stimulation of cytochrome C reduction and oxygen consumption as assessment of human islet quality. Transplantation. 2005;80:1003–1011.
   PubMed Web of Science ®Google Scholar
• Fernandez LA, Hatch EW, Armann B, . Validation of large particle flow cytometry for the analysis and sorting of intact pancreatic islets. Transplantation. 2005;80:729–737.
   PubMed Web of Science ®Google Scholar
• Pisania A. Development of quantitative methods for quality assessment of islets of Langerhans. Ph.D. thesis, 2007, Massachusetts Institute of Technology, Cambridge, MA.
   Google Scholar
• Emamaullee JA, Stanton L, Schur C, . Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation. Diabetes. 2007;56:1289–1298.
   PubMed Web of Science ®Google Scholar
• Berman DM, Cabrera O, Kenyon NM, . Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model. Transplantation. 2007;84:308–315.
   PubMed Web of Science ®Google Scholar
• Lacy PE, Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes. 1967;16:35–39.
   PubMed Web of Science ®Google Scholar
• Papas KK, Pisania A, Wu H, . A stirred microchamber for oxygen consumption rate measurements with pancreatic islets. Biotechnol Bioeng. 2007;98:1071–1082.
   PubMed Web of Science ®Google Scholar
• Ghobrial RR, Boublik M, Winn HJ, . In vivo use of monoclonal antibodies against murine T cell antigens. Clin Immunol Immunopathol. 1989;52:486–506.
   PubMedGoogle Scholar
• Dialynas DP, Quan ZS, Wall KA, . Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J Immunol. 1983;131:2445–2451.
   PubMed Web of Science ®Google Scholar
• Colton CK, Papas KK, Pisania, A, Rappel MJ, Powers DE, O'Neil JJ, Omer A, Weir G, and Bonner-Weir S. Characterization of Islet Preparations, In “Cell Transplantation from Laboratory to Clinic” Craig Halberstadt and Dwaine F. Emerich, editors, Elsevier, Inc., New York, 2006, Chapter 6, pages 85–133.
   Google Scholar
• Suzuki K, Bonner-Weir S, Trivedi N, . Function and survival of macroencapsulated syngeneic islets transplanted into streptozocin-diabetic mice. Transplantation. 1998;66: 21–28.
   PubMed Web of Science ®Google Scholar
• Weir GC, Bonner-Weir S. Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes. 2004;53:S16–S21.
   PubMed Web of Science ®Google Scholar