Effects on airways of short-term exposure to two kinds of wood smoke in a chamber study of healthy humans

References

• Allen RW, Carlsten C, Karlen B, Leckie S, Eeden S, Vedal S, Wong I, Brauer M. 2011. An Air Filter Intervention Study of Endothelial Function among Healthy Adults in a Woodsmoke-impacted Community. Am J Respir Crit Care Med 183:1222–1230.
   PubMed Web of Science ®Google Scholar
• Amann M, Bertok I, Cofala J, Gyarfas F, Heyes C, Klimont Z, Schöpp W and Winiwarter W. 2005. Baseline Scenarios for the Clean Air for Europe (Cafe) Programme: Final Report, Laxenburg, Austria.
   Google Scholar
• Andersson L, Lundberg PA, Barregard L. 2007. Methodological aspects on measurement of Clara cell protein in urine as a biomarker for airway toxicity, compared with serum levels. J Appl Toxicol 27:60–66.
   PubMed Web of Science ®Google Scholar
• Ats/Ers. 2005. Ats/Ers Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005. Am J Respir Crit Care Med, 171:912–930.
   PubMed Web of Science ®Google Scholar
• Bae S, Pan XC, Kim SY, Park K, Kim YH, Kim H, Hong YC. 2010. Exposures to particulate matter and polycyclic aromatic hydrocarbons and oxidative stress in schoolchildren. Environ Health Perspect 118:579–583.
   PubMed Web of Science ®Google Scholar
• Barraza-Villarreal A, Sunyer J, Hernandez-Cadena L, Escamilla-Nuñez MC, Sienra-Monge JJ, Ramírez-Aguilar M, Cortez-Lugo M, Holguin F, Diaz-Sánchez D, Olin AC, Romieu I. 2008. Air pollution, airway inflammation, and lung function in a cohort study of Mexico City schoolchildren. Environ Health Perspect 116:832–838.
   PubMed Web of Science ®Google Scholar
• Barregard L, Sällsten G, Andersson L, Almstrand AC, Gustafson P, Andersson M, Olin AC. 2008. Experimental exposure to wood smoke: Effects on airway inflammation and oxidative stress. Occup Environ Med 65:319–324.
   PubMed Web of Science ®Google Scholar
• Barregard L, Sällsten G, Gustafson P, Andersson L, Johansson L, Basu S, Stigendal L. 2006. Experimental exposure to wood-smoke particles in healthy humans: Effects on markers of inflammation, coagulation, and lipid peroxidation. Inhal Toxicol 18:845–853.
   PubMed Web of Science ®Google Scholar
• Berhane K, Zhang Y, Linn WS, Rappaport EB, Bastain TM, Salam MT, Islam T, Lurmann F, Gilliland FD. 2011. The effect of ambient air pollution on exhaled nitric oxide in the Children’s Health Study. Eur Respir J 37:1029–1036.
   PubMed Web of Science ®Google Scholar
• Bernard A, Carbonnelle S, Nickmilder M, de Burbure C. 2005. Non-invasive biomarkers of pulmonary damage and inflammation: Application to children exposed to ozone and trichloramine. Toxicol Appl Pharmacol 206:185–190.
   PubMed Web of Science ®Google Scholar
• Bernard A, Hermans C, Van Houte G. 1997. Transient increase of serum Clara cell protein (CC16) after exposure to smoke. Occup Environ Med 54:63–65.
   PubMed Web of Science ®Google Scholar
• Bernard AM, Roels HA, Buchet JP, Lauwerys RR. 1994. Serum Clara cell protein: An indicator of bronchial cell dysfunction caused by tobacco smoking. Environ Res 66:96–104.
   PubMed Web of Science ®Google Scholar
• Blomberg A, Mudway I, Svensson M, Hagenbjörk-Gustafsson A, Thomasson L, Helleday R, Dumont X, Forsberg B, Nordberg G, Bernard A. 2003. Clara cell protein as a biomarker for ozone-induced lung injury in humans. Eur Respir J 22:883–888.
   PubMed Web of Science ®Google Scholar
• Boman BC, Forsberg AB, Järvholm BG. 2003. Adverse health effects from ambient air pollution in relation to residential wood combustion in modern society. Scand J Work Environ Health 29:251–260.
   PubMed Web of Science ®Google Scholar
• Borg GAV. 1982. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 14:377–381.
   PubMed Web of Science ®Google Scholar
• Broeckaert F, Arsalane K, Hermans C, Bergamaschi E, Brustolin A, Mutti A, Bernard A. 2000a. Serum clara cell protein: A sensitive biomarker of increased lung epithelium permeability caused by ambient ozone. Environ Health Perspect 108:533–537.
   PubMed Web of Science ®Google Scholar
• Broeckaert F, Clippe A, Knoops B, Hermans C, Bernard A. 2000b. Clara cell secretory protein (CC16): Features as a peripheral lung biomarker. Ann N Y Acad Sci 923:68–77.
   PubMed Web of Science ®Google Scholar
• Brook RD. 2008. Cardiovascular effects of air pollution. Clin Sci 115:175–187.
   PubMed Web of Science ®Google Scholar
• Brook RD, Franklin B, Cascio W, Hong Y, Howard G, Lipsett M, Luepker R, Mittleman M, Samet J, Smith SC Jr, Tager I; Expert Panel on Population and Prevention Science of the American Heart Association. 2004. Air pollution and cardiovascular disease: A statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation 109:2655–2671.
   PubMed Web of Science ®Google Scholar
• Brook RD, Rajagopalan S, Pope CA 3rd, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, Peters A, Siscovick D, Smith SC Jr, Whitsel L, Kaufman JD; American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism. 2010. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation 121:2331–2378.
   PubMed Web of Science ®Google Scholar
• Bräuner EV, Mortensen J, Møller P, Bernard A, Vinzents P, Wåhlin P, Glasius M, Loft S. 2009. Effects of ambient air particulate exposure on blood-gas barrier permeability and lung function. Inhal Toxicol 21:38–47.
   PubMed Web of Science ®Google Scholar
• Danielsen PH, Loft S, Jacobsen NR, Jensen KA, Autrup H, Ravanat JL, Wallin H, Møller P. 2010. Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter. Toxicol Sci 118:574–585.
   PubMed Web of Science ®Google Scholar
• Danielsen PH, Møller P, Jensen KA, Sharma AK, Wallin H, Bossi R, Autrup H, Mølhave L, Ravanat JL, Briedé JJ, de Kok TM, Loft S. 2011. Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines. Chem Res Toxicol 24:168–184.
   PubMed Web of Science ®Google Scholar
• Delfino RJ, Staimer N, Gillen D, Tjoa T, Sioutas C, Fung K, George SC, Kleinman MT. 2006. Personal and ambient air pollution is associated with increased exhaled nitric oxide in children with asthma. Environ Health Perspect 114:1736–1743.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Tran CL. 2002. Inflammation caused by particles and fibers. Inhal Toxicol 14:5–27.
   PubMed Web of Science ®Google Scholar
• Egeghy PP, Hauf-Cabalo L, Gibson R, Rappaport SM. 2003. Benzene and naphthalene in air and breath as indicators of exposure to jet fuel. Occup Environ Med 60:969–976.
   PubMed Web of Science ®Google Scholar
• Ellingsen DG, Ulvestad B, Andersson L, Barregard L. 2010. Pneumoproteins and inflammatory biomarkers in asphalt pavers. Biomarkers 15:498–507.
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Soukup JM, Case M, Dailey LA, Richards J, Berntsen J, Devlin RB, Stone S, Rappold A. 2011. Exposure to wood smoke particles produces inflammation in healthy volunteers. Occup Environ Med. DOI: 10.1136/oem.2011.065276.
   PubMed Web of Science ®Google Scholar
• Hedberg E, Kristensson A, Ohlsson M, Johansson C, Johansson P-Å Swietlicki, E, Vesely V, Wideqvist U, Westerholm R. 2002. Chemical and physical characterization of emissions from birch wood combustion in a wood stove. Atmospher Environ 36:4823–4837.
   Web of Science ®Google Scholar
• Helleday R, Segerstedt B, Forsberg B, Mudway I, Nordberg G, Bernard A, Blomberg A. 2006. Exploring the time dependence of serum clara cell protein as a biomarker of pulmonary injury in humans. Chest 130:672–675.
   PubMed Web of Science ®Google Scholar
• Hermans C, Aly O, Nyberg BI, Peterson C, Bernard A. 1998. Determinants of Clara cell protein (CC16) concentration in serum: A reassessment with two different immunoassays. Clin Chim Acta 272:101–110.
   PubMed Web of Science ®Google Scholar
• Hermans C, Bernard A. 1999. Lung epithelium-specific proteins: Characteristics and potential applications as markers. Am J Respir Crit Care Med 159:646–678.
   PubMed Web of Science ®Google Scholar
• Hermans C, Knoops B, Wiedig M, Arsalane K, Toubeau G, Falmagne P, Bernard A. 1999. Clara cell protein as a marker of Clara cell damage and bronchoalveolar blood barrier permeability. Eur Respir J 13:1014–1021.
   PubMed Web of Science ®Google Scholar
• Hoegh SV, Sorensen GL, Tornoe I, Lottenburger T, Ytting H, Nielsen HJ, Junker P, Holmskov U. 2010. Long-term stability and circadian variation in circulating levels of surfactant protein D. Immunobiology 215:314–320.
   PubMed Web of Science ®Google Scholar
• Hornung RW, Reed LD. 1990. Estimation of average concentration in the presence of non-detectable values. Appl Occup Environ Hyg 5:48–51.
   Google Scholar
• Hueglin C, Gaegauf C, Künzel S, Burtscher H. 1997. Characterization of Wood Combustion Particles:  Morphology, Mobility, and Photoelectric Activity. Environ Sci Tech 31:3439–3447.
   Web of Science ®Google Scholar
• Isik B, Isik RS, Akyildiz L, Topçu F. 2005. Does biomass exposure affect serum MDA levels in women? Inhal Toxicol 17:695–697.
   PubMed Web of Science ®Google Scholar
• Jacquemin B, Lanki T, Yli-Tuomi T, Vallius M, Hoek G, Heinrich J, Timonen K, Pekkanen J. 2009. Source category-specific PM2.5 and urinary levels of Clara cell protein CC16. The ULTRA study. Inhal Toxicol 21:1068–1076.
   PubMed Web of Science ®Google Scholar
• Jansen KL, Larson TV, Koenig JQ, Mar TF, Fields C, Stewart J, Lippmann M. 2005. Associations between health effects and particulate matter and black carbon in subjects with respiratory disease. Environ Health Perspect 113:1741–1746.
   PubMed Web of Science ®Google Scholar
• Johannesson S, Bergemalm-Rynell K, Strandberg B, Sallsten G. 2009. Indoor concentrations of fine particles and particle-bound Pahs in Gothenburg, Sweden. Journal of Physics: Conference Series, 151, 012006.
   Google Scholar
• Jorres RA. 2000. Modelling the production of nitric oxide within the human airways. Eur Respir J 16:555–560.
   PubMed Web of Science ®Google Scholar
• Kliucininkas L, Martuzevicius D, Krugly E, Prasauskas T, Kauneliene V, Molnar P, Strandberg B. 2011. Indoor and outdoor concentrations of fine particles, particle-bound PAHs and volatile organic compounds in Kaunas, Lithuania. J Environ Monit 13:182–191.
   PubMed Web of Science ®Google Scholar
• Kocbach-Bolling Ata Sallsten, G, Braun A, Westerholm R, Boman J, Dahlmann Hj Selstedt, M, Cassee F, Sandstorm T, Schwatze Pe Herseth, Ji., Manuscript. Wood smoke particles from different combustion phases induce similar pro-inflammatory effects in co-cultures.
   Google Scholar
• Kocbach Bølling A, Pagels J, Yttri KE, Barregard L, Sallsten G, Schwarze PE, Boman C. 2009. Health effects of residential wood smoke particles: The importance of combustion conditions and physicochemical particle properties. Part Fibre Toxicol 6:29.
   PubMed Web of Science ®Google Scholar
• Langrish JP, Lundbäck M, Barath S, Söderberg S, Mills NL, Newby DE, Sandström T, Blomberg A. 2010. Exposure to nitrogen dioxide is not associated with vascular dysfunction in man. Inhal Toxicol 22:192–198.
   PubMed Web of Science ®Google Scholar
• Levin BL. 1988. State mandates for mental health, alcohol, and substance abuse benefits: Implications for HMOs. GHAA J 9:48–69.
   PubMedGoogle Scholar
• Mar TF, Jansen K, Shepherd K, Lumley T, Larson TV, Koenig JQ. 2005. Exhaled nitric oxide in children with asthma and short-term PM2.5 exposure in Seattle. Environ Health Perspect 113:1791–1794.
   PubMed Web of Science ®Google Scholar
• Mcdonald JD, Zielinska B, Fujita EM, Sagebiel JC, Chow JC, Watson JG. 2000. Fine Particle and Gaseous Emission Rates from Residential Wood Combustion. Environ Sci Tech 34:2080–2091.
   Web of Science ®Google Scholar
• Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, Sandström T, Blomberg A, Newby DE. 2009. Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med 6:36–44.
   PubMedGoogle Scholar
• Molnar P, Gustafson P, Johannesson S, Boman J, Barregard L, Sallsten G. 2005. Domestic wood burning and Pm2.5 trace elements: Personal exposures, indoor and outdoor levels. Atmospher Environ 39:2643–2653.
   Web of Science ®Google Scholar
• Naeher LP, Brauer M, Lipsett M, Zelikoff JT, Simpson CD, Koenig JQ, Smith KR. 2007. Woodsmoke health effects: A review. Inhal Toxicol 19:67–106.
   PubMed Web of Science ®Google Scholar
• Olin AC, Aldenbratt A, Ekman A, Ljungkvist G, Jungersten L, Alving K, Torén K. 2001a. Increased nitric oxide in exhaled air after intake of a nitrate-rich meal. Respir Med 95:153–158.
   PubMed Web of Science ®Google Scholar
• Olin AC, Stenfors N, Torén K, Blomberg A, Helleday R, Ledin MC, Ljungkvist G, Ekman A, Sandström T. 2001b. Nitric oxide (NO) in exhaled air after experimental ozone exposure in humans. Respir Med 95:491–495.
   PubMed Web of Science ®Google Scholar
• Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdörster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang LS, Utell MJ. 2004. Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhal Toxicol 16 Suppl 1:59–72.
   PubMed Web of Science ®Google Scholar
• Pope CA 3rd, Dockery DW. 2006. Health effects of fine particulate air pollution: Lines that connect. J Air Waste Manag Assoc 56:709–742.
   PubMed Web of Science ®Google Scholar
• Riddervold IS, Bønløkke JH, Mølhave L, Massling A, Jensen B, Grønborg TK, Bossi R, Forchhammer L, Kjærgaard SK, Sigsgaard T. 2011. Wood smoke in a controlled exposure experiment with human volunteers. Inhal Toxicol 23:277–288.
   PubMed Web of Science ®Google Scholar
• Riddervold Skogstad I. 2011. Acute Health effects of wood smoke exposure. PhD Thesis, Aarhus University.
   Google Scholar
• Romieu I, Barraza-Villarreal A, Escamilla-Nuñez C, Almstrand AC, Diaz-Sanchez D, Sly PD, Olin AC. 2008. Exhaled breath malondialdehyde as a marker of effect of exposure to air pollution in children with asthma. J Allergy Clin Immunol 121:903–9.e6.
   PubMed Web of Science ®Google Scholar
• Rothman KJ. 1990. No adjustments are needed for multiple comparisons. Epidemiology 1:43–46.
   PubMedGoogle Scholar
• Sallsten G, Gustafson P, Johansson L, Johannesson S, Molnár P, Strandberg B, Tullin C, Barregard L. 2006. Experimental wood smoke exposure in humans. Inhal Toxicol 18:855–864.
   PubMed Web of Science ®Google Scholar
• Schwarze PE, Ovrevik J, Låg M, Refsnes M, Nafstad P, Hetland RB, Dybing E. 2006. Particulate matter properties and health effects: Consistency of epidemiological and toxicological studies. Hum Exp Toxicol 25:559–579.
   PubMed Web of Science ®Google Scholar
• Sehlstedt M, Dove R, Boman C, Pagels J, Swietlicki E, Löndahl J, Westerholm R, Bosson J, Barath S, Behndig AF, Pourazar J, Sandström T, Mudway IS, Blomberg A. 2010. Antioxidant airway responses following experimental exposure to wood smoke in man. Part Fibre Toxicol 7:21.
   PubMed Web of Science ®Google Scholar
• Shijubo N, Itoh Y, Yamaguchi T, Shibuya Y, Morita Y, Hirasawa M, Okutani R, Kawai T, Abe S. 1997. Serum and BAL Clara cell 10 kDa protein (CC10) levels and CC10-positive bronchiolar cells are decreased in smokers. Eur Respir J 10:1108–1114.
   PubMed Web of Science ®Google Scholar
• Sørensen M, Daneshvar B, Hansen M, Dragsted LO, Hertel O, Knudsen L, Loft S. 2003. Personal PM2.5 exposure and markers of oxidative stress in blood. Environ Health Perspect 111:161–166.
   PubMed Web of Science ®Google Scholar
• Steerenberg PA, Snelder JB, Fischer PH, Vos JG, van Loveren H, van Amsterdam JG. 1999. Increased exhaled nitric oxide on days with high outdoor air pollution is of endogenous origin. Eur Respir J 13:334–337.
   PubMed Web of Science ®Google Scholar
• Strandberg B, Sunesson Al Olsson, K, Levin Jo Ljungqvist, G, Sundgren M, Sallsten G, Barregard L. 2005. Evaluation of two types of diffusive samplers and adsorbents for measuring 1,3-butadiene and benzene in air. Atmospher Environ 39:4101–4110.
   Web of Science ®Google Scholar
• Swiston JR, Davidson W, Attridge S, Li GT, Brauer M, van Eeden SF. 2008. Wood smoke exposure induces a pulmonary and systemic inflammatory response in firefighters. Eur Respir J 32:129–138.
   PubMed Web of Science ®Google Scholar
• Timonen KL, Hoek G, Heinrich J, Bernard A, Brunekreef B, de Hartog J, Hämeri K, Ibald-Mulli A, Mirme A, Peters A, Tiittanen P, Kreyling WG, Pekkanen J. 2004. Daily variation in fine and ultrafine particulate air pollution and urinary concentrations of lung Clara cell protein CC16. Occup Environ Med 61:908–914.
   PubMed Web of Science ®Google Scholar
• Traynor GW, Apte MG, Carruthers AR, Dillworth JF, Grimsrud DT, Gundel LA. 1987. Indoor air pollution due to emissions from wood-burning stoves. Environ Sci Technol 21:691–697.
   PubMed Web of Science ®Google Scholar
• Weimer S, Alfarra Mr Schreiber, D, Mohr M, Prévôt Ash Baltensperger, U. 2008. Organic aerosol mass spectral signatures from wood-burning emissions: Influence of burning conditions and wood type. J Geophys Res 113: D10304.
   Web of Science ®Google Scholar