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Inhalation Toxicology
International Forum for Respiratory Research
Volume 24, 2012 - Issue 13
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Review Article

Clinical and paraclinical guidelines for management of sulfur mustard induced bronchiolitis obliterans; from bench to bedside

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Pages 900-906 | Received 08 Jun 2012, Accepted 27 Aug 2012, Published online: 05 Nov 2012

References

  • Aghanouri R, Ghanei M, Aslani J, Keivani-Amine H, Rastegar F, Karkhane A. 2004. Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard. Am J Physiol Lung Cell Mol Physiol 287:L1160–L1164.
  • Akira M, Toyokawa K, Inoue Y, Arai T. 2009. Quantitative CT in chronic obstructive pulmonary disease: inspiratory and expiratory assessment. AJR Am J Roentgenol 192:267–272.
  • Amiri S, Ghazanfari T, Yaraee R, Salimi H, Ebtekar M, Shams J, Ghasemi H, Pourfarzam S, Moin A, Sharifnia Z, Soroush MR, Faghihzadeh S, Hassan ZM. 2009. Serum levels of GM-CSF 20 years after sulfur mustard exposure: Sardasht-Iran Cohort Study. Int Immunopharmacol 9:1499–1503.
  • Attaran D, Lari SM, Khajehdaluee M, Ayatollahi H, Towhidi M, Asnaashari A, Marallu HG, Mazloomi M, Mood MB. 2009. Highly sensitive C-reactive protein levels in Iranian patients with pulmonary complication of sulfur mustard poisoning and its correlation with severity of airway diseases. Hum Exp Toxicol 28:739–745.
  • Bagheri MH, Hosseini SK, Mostafavi SH, Alavi SA. 2003. High-resolution CT in chronic pulmonary changes after mustard gas exposure. Acta Radiol 44:241–245.
  • Balali-Mood M, Hefazi M, Mahmoudi M, Jalali E, Attaran D, Maleki M, Razavi ME, Zare G, Tabatabaee A, Jaafari MR. 2005. Long-term complications of sulphur mustard poisoning in severely intoxicated Iranian veterans. Fundam Clin Pharmacol 19:713–721.
  • Balali-Mood M, Hefazi M. 2006. Comparison of early and late toxic effects of sulfur mustard in Iranian veterans. Basic Clin Pharmacol Toxicol 99:273–282.
  • Basseri B, Enayati P, Marchevsky A, Papadakis KA. 2010. Pulmonary manifestations of inflammatory bowel disease: case presentations and review. J Crohns Colitis 4:390–397.
  • Beheshti J, Mark EJ, Akbaei HM, Aslani J, Ghanei M. 2006. Mustard lung secrets: long term clinicopathological study following mustard gas exposure. Pathol Res Pract 202:739–744.
  • Bijani Kh, Moghadamnia AA. 2002. Long-term effects of chemical weapons on respiratory tract in Iraq-Iran war victims living in Babol (North of Iran). Ecotoxicol Environ Saf 53:422–424.
  • Car BD, Meloni F, Luisetti M, Semenzato G, Gialdroni-Grassi G, Walz A. 1994. Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis. Am J Respir Crit Care Med 149:655–659.
  • Chan A, Allen R. 2004. Bronchiolitis obliterans: an update. Curr Opin Pulm Med 10:133–141.
  • Colby TV. 1998. Bronchiolitis. Pathologic considerations. Am J Clin Pathol 109:101–109.
  • Danilko KV, Korytina GF, Akhmidishina LZ, Ianbaeva DG, Zagidullin ShZ, Victorova TV. 2007. [Association of cytokines genes (ILL, IL1RN, TNF, LTA, IL6, IL8, IL0) polymorphic markers with chronic obstructive pulmonary disease]. Mol Biol (Mosk) 41:26–36.
  • Dirksen A. 2008. Is CT a new research tool for COPD? Clin Respir J 2 Suppl 1:76–83.
  • Dompeling E, Jöbsis Q, Vandevijver NM, Wesseling G, Hendriks H. 2004. Chronic bronchiolitis in a 5-yr-old child after exposure to sulphur mustard gas. Eur Respir J 23:343–346.
  • Dosreis GA, Borges VM, Zin WA. 2004. The central role of Fas-ligand cell signaling in inflammatory lung diseases. J Cell Mol Med 8:285–293.
  • Egan JJ. 2004. Obliterative bronchiolitis after lung transplantation: a repetitive multiple injury airway disease. Am J Respir Crit Care Med 170:931–932.
  • El-Gamel A, Sim E, Hasleton P, Hutchinson J, Yonan N, Egan J, Campbell C, Rahman A, Sheldon S, Deiraniya A, Hutchinson IV. 1999. Transforming growth factor β (TGF-β) and obliterative bronchiolitis following pulmonary transplantation. J Heart Lung Transplant 18:828–837.
  • Emad A, Emad Y. 2007. Levels of cytokine in bronchoalveolar lavage (BAL) fluid in patients with pulmonary fibrosis due to sulfur mustard gas inhalation. J Interferon Cytokine Res 27:38–43.
  • Emad A, Rezaian GR. 1997. The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: analysis of 197 cases. Chest 112:734–738.
  • Emad A, Rezaian GR. 1999. Immunoglobulins and cellular constituents of the BAL fluid of patients with sulfur mustard gas-induced pulmonary fibrosis. Chest 115:1346–1351.
  • Essadki O, Grenier P. 1999. [Bronchiolitis: computed tomographic findings]. J Radiol 80:17–24.
  • Estenne M, Hertz MI. 2002. Bronchiolitis obliterans after human lung transplantation. Am J Respir Crit Care Med 166:440–444.
  • Estenne M, Maurer JR, Boehler A, Egan JJ, Frost A, Hertz M, Mallory GB, Snell GI, Yousem S. 2002. Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant 21:297–310.
  • Garg K, Lynch DA, Newell JD, King TE Jr. 1994. Proliferative and constrictive bronchiolitis: classification and radiologic features. AJR Am J Roentgenol 162:803–808.
  • Ghanei M, Akhlaghpoor S, Moahammad MM, Aslani J. 2004a. Tracheobronchial stenosis following sulfur mustard inhalation. Inhal Toxicol 16:845–849.
  • Ghanei M, Fathi H, Mohammad MM, Aslani J, Nematizadeh F. 2004b. Long-term respiratory disorders of claimers with subclinical exposure to chemical warfare agents. Inhal Toxicol 16:491–495.
  • Ghanei M, Mokhtari M, Mohammad MM, Aslani J. 2004c. Bronchiolitis obliterans following exposure to sulfur mustard: chest high resolution computed tomography. Eur J Radiol 52:164–169.
  • Ghanei M, Hosseini AR, Arabbaferani Z, Shahkarami E. 2005a. Evaluation of chronic cough in chemical chronic bronchitis patients. Environ Toxicol Pharmacol 20:6–10.
  • Ghanei M, Khalili AR, Arab MJ, Mojtahedzadeh M, Aslani J, Lessan-Pezeshki M, Panahi Y, Alaeddini F. 2005b. Diagnostic and therapeutic value of short-term corticosteroid therapy in exacerbation of mustard gas-induced chronic bronchitis. Basic Clin Pharmacol Toxicol 97:302–305.
  • Ghanei M, Akbari Moqadam F, Mohammad MM, Aslani J. 2006a. Tracheobronchomalacia and air trapping after mustard gas exposure. Am J Respir Crit Care Med 173:304–309.
  • Ghanei M, Khedmat H, Mardi F, Hosseini A. 2006b. Distal esophagitis in patients with mustard-gas induced chronic cough. Dis Esophagus 19:285–288.
  • Ghanei M, Amiri S, Akbari H, Kosari F, Khalili AR, Alaeddini F, Aslani J, Giardina C, Haines DD. 2007a. Correlation of sulfur mustard exposure and tobacco use with expression (immunoreactivity) of p53 protein in bronchial epithelium of Iranian “mustard lung” patients. Mil Med 172:70–74.
  • Ghanei M, Harandi AA. 2007b. Long term consequences from exposure to sulfur mustard: a review. Inhal Toxicol 19:451–456.
  • Ghanei M, Tazelaar HD, Harandi A, Peyman M, Hoseini Akbari HM, Aslani J. 2007c. Clinical differentiation between resistant asthma and chronic bronchiolitis: testing a practical approach. Iran J Allergy Asthma Immunol 6:207–214.
  • Ghanei M, Tazelaar HD, Chilosi M, Harandi AA, Peyman M, Akbari HM, Shamsaei H, Bahadori M, Aslani J, Mohammadi A. 2008. An international collaborative pathologic study of surgical lung biopsies from mustard gas-exposed patients. Respir Med 102:825–830.
  • Ghanei M, Harandi AA. 2011. Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard: a review. Inhal Toxicol 23:363–371.
  • Ghazanfari T, Sharifnia Z, Yaraee R, Pourfarzam S, Kariminia A, Mahlojirad M, Faghihzadeh S, Jalali-Nodoushan MR, Ardestani SK, Soroush MR, Amiri S, Hassan ZM, Ghavami S, Ghanei M. 2009. Serum soluble Fas ligand and nitric oxide in long-term pulmonary complications induced by sulfur mustard: Sardasht-Iran Cohort Study. Int Immunopharmacol 9:1489–1493.
  • Gosink BB, Friedman PJ, Liebow AA. 1973. Bronchiolitis obliterans. Roentgenologic-pathologic correlation. Am J Roentgenol Radium Ther Nucl Med 117:816–832.
  • Hassan ZM, Ebtekar M, Ghanei M, Taghikhani M, Noori Daloii MR, Ghazanfari T. 2006. Immunobiological consequences of sulfur mustard contamination. Iran J Allergy Asthma Immunol 5:101–108.
  • Hefazi M, Attaran D, Mahmoudi M, Balali-Mood M. 2005. Late respiratory complications of mustard gas poisoning in Iranian veterans. Inhal Toxicol 17:587–592.
  • Heng D, Sharples LD, McNeil K, Stewart S, Wreghitt T, Wallwork J. 1998. Bronchiolitis obliterans syndrome: incidence, natural history, prognosis, and risk factors. J Heart Lung Transplant 17:1255–1263.
  • Hwang JH, Kim TS, Lee KS, Choi YH, Han J, Chung MP, Kwon OJ, Rhee CH. 1997. Bronchiolitis in adults: pathology and imaging. J Comput Assist Tomogr 21:913–919.
  • Jafari M, Ghanei M. 2010. Evaluation of plasma, erythrocytes, and bronchoalveolar lavage fluid antioxidant defense system in sulfur mustard-injured patients. Clin Toxicol (Phila) 48:184–192.
  • Kaditis AG, Gondor M, Nixon PA, Webber S, Keenan RJ, Kaye R, Kurland G. 2000. Airway complications following pediatric lung and heart-lung transplantation. Am J Respir Crit Care Med 162:301–309.
  • Kang EY, Woo OH, Shin BK, Yong HS, Oh YW, Kim HK. 2009. Bronchiolitis: classification, computed tomographic and histopathologic features, and radiologic approach. J Comput Assist Tomogr 33:32–41.
  • Khateri S, Ghanei M, Keshavarz S, Soroush M, Haines D. 2003. Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent. J Occup Environ Med 45:1136–1143.
  • Law L, Zheng L, Orsida B, Levvey B, Oto T, Kotsimbos AT, Snell GI, Williams TJ. 2005. Early changes in basement membrane thickness in airway walls post-lung transplantation. J Heart Lung Transplant 24:1571–1576.
  • Lee TM, Lin MS, Chang NC. 2008. Usefulness of C-reactive protein and interleukin-6 as predictors of outcomes in patients with chronic obstructive pulmonary disease receiving pravastatin. Am J Cardiol 101:530–535.
  • Mehrani H, Ghanei M, Aslani J, Golmanesh L. 2009. Bronchoalveolar lavage fluid proteomic patterns of sulfur mustard-exposed patients. Proteomics Clin Appl 3:1191–1200.
  • Mirsadraee M, Attaran D, Boskabady MH, Towhidi M. 2005. Airway hyperresponsiveness to methacholine in chemical warfare victims. Respiration 72:523–528.
  • Mroz BJ, Sexauer WP, Meade A, Balsara G. 1997. Hemoptysis as the presenting symptom in bronchiolitis obliterans organizing pneumonia. Chest 111:1775–1778.
  • Müller NL, Miller RR. 1995. Diseases of the bronchioles: CT and histopathologic findings. Radiology 196:3–12.
  • Myers JL, Colby TV. 1993. Pathologic manifestations of bronchiolitis, constrictive bronchiolitis, cryptogenic organizing pneumonia, and diffuse panbronchiolitis. Clin Chest Med 14:611–622.
  • Myers PO, Gasche-Soccal PM, Robert JH, Pache JC, Bongiovanni M. 2009. Neuroendocrine proliferation after lung transplantation. J Heart Lung Transplant 28:406–408.
  • Nash EF, Volling C, Gutierrez CA, Tullis E, Coonar A, McRae K, Keshavjee S, Singer LG, Durie PR, Chaparro C. 2012. Outcomes of patients with cystic fibrosis undergoing lung transplantation with and without cystic fibrosis-associated liver cirrhosis. Clin Transplant 26:34–41.
  • Nocker RE, Schoonbrood DF, van de Graaf EA, Hack CE, Lutter R, Jansen HM, Out TA. 1996. Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol 109:183–191.
  • Pourfarzam S, Ghazanfari T, Yaraee R, Ghasemi H, Hassan ZM, Faghihzadeh S, Ardestani SK, Kariminia A, Fallahi F, Soroush MR, Merasizadeh J, Mahlojirad M, Naghizadeh MM, Ghanei M. 2009. Serum levels of IL-8 and IL-6 in the long term pulmonary complications induced by sulfur mustard: Sardasht-Iran Cohort Study. Int Immunopharmacol 9:1482–1488.
  • Ryu JH, Myers JL, Swensen SJ. 2003. Bronchiolar disorders. Am J Respir Crit Care Med 168:1277–1292.
  • Scott AI, Sharples LD, Stewart S. 2005. Bronchiolitis obliterans syndrome: risk factors and therapeutic strategies. Drugs 65:761–771.
  • Shohrati M, Shamspour N, Babaei F, Harandi AA, Mohsenifar A, Aslani J, Ghanei M. 2010. Evaluation of activity and phenotype of α1-antitrypsin in a civil population with respiratory complications following exposure to sulfur mustard 20 years ago. Biomarkers 15:47–51.
  • Skeens JL, Fuhrman CR, Yousem SA. 1989. Bronchiolitis obliterans in heart-lung transplantation patients: radiologic findings in 11 patients. AJR Am J Roentgenol 153:253–256.
  • Sohrabpour H. 1984. Clinical manifestations of chemical agents on Iranian combatants during Iran-Iraq conflict. Arch Belg Suppl:291–297.
  • Stanbrook MB, Kesten S. 1999. Bronchial hyperreactivity after lung transplantation predicts early bronchiolitis obliterans. Am J Respir Crit Care Med 160:2034–2039.
  • Stern EJ, Frank MS. 1994. Small-airway diseases of the lungs: findings at expiratory CT. AJR Am J Roentgenol 163:37–41.
  • Sweatman MC, Millar AB, Strickland B, Turner-Warwick M. 1990. Computed tomography in adult obliterative bronchiolitis. Clin Radiol 41:116–119.
  • Thomason JW, Rice TW, Milstone AP. 2003. Bronchiolitis obliterans in a survivor of a chemical weapons attack. JAMA 290:598–599.
  • Visscher DW, Myers JL. 2006. Bronchiolitis: the pathologist’s perspective. Proc Am Thorac Soc 3:41–47.
  • Webb WR, Stein MG, Finkbeiner WE, Im JG, Lynch D, Gamsu G. 1988. Normal and diseased isolated lungs: high-resolution CT. Radiology 166:81–87.
  • Wohl ME, Chernick V. 1978. State of the art: bronchiolitis. Am Rev Respir Dis 118:759–781.
  • Yaraee R, Ghazanfari T, Ebtekar M, Ardestani SK, Rezaei A, Kariminia A, Faghihzadeh S, Mostafaie A, Vaez-Mahdavi MR, Mahmoudi M, Naghizadeh MM, Soroush MR, Hassan ZM. 2009. Alterations in serum levels of inflammatory cytokines (TNF, IL-1α, IL-1β and IL-1Ra) 20 years after sulfur mustard exposure: Sardasht-Iran cohort study. Int Immunopharmacol 9:1466–1470.
  • Zarchi K, Akbar A, Naieni KH. 2004. Long-term pulmonary complications in combatants exposed to mustard gas: a historical cohort study. Int J Epidemiol 33:579–581.

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