Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 25, 2013 - Issue 3
148
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Baseline airway inflammation may be a determinant of the response to ozone exposure in asthmatic patients

, , , , , , , & show all
Pages 127-133 | Received 22 Aug 2012, Accepted 31 Dec 2012, Published online: 19 Feb 2013

References

  • Aris RM, Tager I, Christian D, et al. (1995). Methacholine responsiveness is not associated with O3-induced decreases in FEV1. Chest 107:621–8
  • Bacci E, Cianchetti S, Carnevali S, et al. (2002). Induced sputum is a reproducible method to assess airway inflammation in asthma. Mediators Inflamm 11:293–8
  • Balmes JR. (2011). How does diesel exhaust impact asthma? Thorax 66:4–6
  • Balmes JR, Chen LL, Scannell C, et al. (1996). Ozone-induced decrements in FEV1 and FVC do not correlate with measures of inflammation. Am J Respir Crit Care Med 153:904–9
  • Basha MA, Gross KB, Gwizdala CJ, et al. (1994). Bronchoalveolar lavage neutrophilia in asthmatic and healthy volunteers after controlled exposure to ozone and filtered purified air. Chest 106:1757–65
  • Behndig AF, Larsson N, Brown JL, et al. (2011). Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma. Thorax 66:12–8
  • Bergamaschi E, De Palma G, Mozzoni P, et al. (2001). Polymorphism of quinone-metabolizing enzymes and susceptibility to ozone-induce acute effect. Am J Resp Crit Care Med 163:1426–31
  • Bernstein JA, Alexis N, Barnes C, et al. (2004). Health effects of air pollution. J Allergy Clin Immunol 114:1116–23
  • Blomberg A, Mudway IS, Nordenhall C, et al. (1999). Ozone-induced lung function decrements do not correlate with early airway inflammatory or antioxidant responses. Eur Respir J 13:1418–28
  • Chen C, Arjomandi M, Tager IB, et al. (2007). Effects of antioxidant enzyme polymorphisms on ozone-induced lung function changes. Eur Respir J 30:677–83
  • Chinn S. (1991). Statistics in respiratory medicine: 2. Repeatability and method comparison. Thorax 46:432–4
  • David GL, Romieu I, Sienra-Monge JJ, et al. (2003). Nicotinamide adenine dinucleotide (phosphate) reduced quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma. Am J Respir Crit Care Med 168:1199–204
  • Frampton MW, Morrow PE, Torres A, et al. (1997). Ozone responsiveness in smokers and nonsmokers. Am J Respir Crit Care Med 155:116–21
  • Global Initiative for Asthma, National Institute of Health, National Heart Lung and Blood Institute. (2010). Global strategy for asthma management and prevention. NHLBI/WHO workshop report no. 02-3659. Available from: http://www.ginasthma.org/guideline-report-2010.html [last accessed 30 Jan 2013].
  • Hernandez ML, Lay JC, Harris B, et al. (2010). Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone. J Allergy Clin Immunol 126:537–44
  • Holz O, Jörres RA, Timm P, et al. (1999). Ozone-induced airway inflammatory changes differ between individuals and are reproducible. Am J Respir Crit Care Med 159:776–84
  • Holz O, Khalilieh S, Ludwig-Sengpiel A, et al. (2010). SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects. Eur Respir J 35:564–70
  • Jorres RA, Holz O, Zachgo W, et al. (2000). The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies. Am J Respir Crit Care Med 161:1855–61
  • Khatri SB, Holguin FC, Ryan PB, et al. (2009). Association of ambient ozone exposure with airway inflammation and allergy in adults with asthma. J Asthma 46:777–85
  • Kelly FJ, Fussell JC. (2011). Air pollution and airway disease. Clin Exp Allergy. 41:1059–71
  • Kim CS, Alexis NE, Rappold AG, et al. (2011). Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours. Am J Respir Crit Care Med 183:1215–21
  • Koren HS, Devlin RB, Graham DE, et al. (1989). Ozone induced inflammation in the lower airways of human subjects. Am Rev Resp Dis 139:407–15
  • Liu L, oon R, Chen L, et al. (2009). Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect 117:668–74
  • McConnell R, Berhane K, Gilliand F, et al. (2002). Asthma in exercising children exposed to ozone: a cohort study. Lancet 359:386–91
  • McDonnell WF, Muller KE, Bromberg PA, Shy CM. (1993). Predictors of individual differences in acute response to ozone exposure. Am Rev Respir Dis 147:818–25
  • McDonnell WF, Stewart PW, Andreoni S, et al. (1997). Prediction of ozone-induced FEV1 changes. Effects of concentration, duration and ventilation. Am J Respir Crit Care Med 156:715–22
  • Miller MR, Hankinson J, Brusasco V, et al. (2010). Standardisation of lung function testing: the authors' replies to readers' comments. Eur Respir J. 36:1496–8
  • Mudway IS, Stenfors N, Blomberg A, et al. (2001). Differences in basal airway antioxidant concentrations are not predictive of individual responsiveness to ozone: a comparison of healthy and mild asthmatic subjects. Free Radic Biol Med 15:962–74
  • Nightingale JA, Rogers DF, Chung KF, Barnes PJ. (2000). No effect of inhaled budesonide on the response to inhaled ozone in normal subjects. Am J Respir Crit Care Med 161:479–86
  • Paggiaro PL, Dente FL, Morelli MC, et al. (1994). Postallergen inhaled budesonide reduces late asthmatic response and inhibits the associated increase of airway responsiveness to methacholine in asthmatics. Am J Respir Crit Care Med 149:1447–51
  • Peden DB. (2001). Air pollution in asthma: effect of pollutants on airway inflammation. Ann Allergy Asthma Immunol 87:12–17
  • Scannell C, Chen L, Aris BM, et al. (1996). Greater ozone-induced inflammatory responses in subjects with asthma. Am J Respir Crit Care Med 54:24–9
  • Stenfors N, Pourazar J, Blomberg A, et al. (2002). Effect of ozone on bronchial mucosal inflammation in asthmatic and healthy subjects. Respir Med 96:352–8
  • Vagaggini B, Bartoli ML, Cianchetti S, et al. (2010). Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone. Respir Res 19:11–15
  • Vagaggini B, Carnevali S, Macchioni P, et al. (1999). Airway inflammatory response to ozone in subjects with different asthma severity. Eur Respir J 13:274–80
  • Vagaggini B, Cianchetti S, Bartoli M, et al. (2007). Prednisone blunts airway neutrophilic inflammatory response due to ozone exposure in asthmatic subjects. Respiration 74:61–8
  • Vagaggini B, Taccola M, Conti I, et al. (2001). Budesonide reduces neutrophilic but not functional airway response to ozone in mild asthmatics. Am J Respir Crit Care Med 164:2172–6
  • van Rensen ELJ, Straathof KCM, Veselic-Charvat MA, et al. (1999). Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma. Thorax 54:403–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.