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Inhalation Toxicology
International Forum for Respiratory Research
Volume 26, 2014 - Issue 5
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Research Article

Assessment of the risk of respiratory sensitization from fragrance allergens released by air fresheners

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Pages 310-318 | Received 25 Nov 2013, Accepted 23 Jan 2014, Published online: 18 Mar 2014

References

  • Arts JHE, De Jong WH, Van Triel JJ, et al. (2008). The respiratory local lymph node assay as a tool to study respiratory sensitizers. Toxicol Sci 106:423–34
  • Arts JHE, Kuper CF. (2007). Animal models to test respiratory allergy of low molecular weight chemicals: a guidance. Methods 41:61–71
  • Arts JHE, Kuper CF, Spoor SM, Bloksma N. (1998). Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals. Toxicol Appl Pharmacol 152:66–76
  • Basketter DA, Kimber I. (2011). Assessing the potency of respiratory allergens: uncertainties and challenges. Regul Toxicol Pharmacol 61:365–72
  • Baur X, Schneider EM, Wieners D, Czuppon AB. (1999). Occupational asthma to perfume. Allergy 54:1334–5
  • Bernstein JA. (1996). Overview of diisocyanate occupational asthma. Toxicology 111:181–9
  • Beuc. (2005). The European Consumers Organisation. Emission of chemicals by air fresheners – tests on 74 consumer products sold in Europe
  • Bremmer HJ, Prud homme de Lodder LCH, van Engelen JGM. (2006). Cosmetics Fact Sheet. To assess the risks for the consumer. Updated version for ConsExpo 4. RIVM report 320104001. Available from: http://www.rivm.nl/bibliotheek/rapporten/320104001.pdf. [Last accessed: 19 Feb 2014]
  • Christensson JB, Johansson S, Hagvall L, et al. (2008). Limonene hydroperoxide analogues differ in allergenic activity. Contact Dermatitis 59:344–52
  • De Jong WH, Arts JH, De Klerk A, et al. (2009). Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure. Toxicology 261:103–11
  • Delmaar JE. (2011). Emission of chemical substances from solid matrices: a method for consumer exposure assessment. RIVM report 320104011. Available from: http://www.rivm.nl/dsresource?objectid=rivmp:24644&type=org&disposition=inline. [Last accessed: 19 Feb 2014]
  • Delmaar JE, Bremmer HJ. (2009). The ConsExpo spray model – modelling and experimental validation of the inhalation exposure of consumers to aerosols from spray cans and trigger sprays RIVM report 320104005. Available from: http://www.rivm.nl/dsresource?objectid=rivmp:13100&type=org&disposition=inline
  • Farraj AK, Harkema JR, Kaminski NE. (2004). Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice. Toxicol Sci 79:315–25
  • Garssen J, Nijkamp FP, Van Der Vliet H, Van Loveren H. (1991). T-cell-mediated induction of airway hyperreactivity in mice. Am Rev Respir Dis 144:931–8
  • Gerberick GF, Ryan CA, Kern PS, et al. (2005). Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 16:157–202
  • Heederik D, Henneberger PK, Redlich CA. (2012). Primary prevention: exposure reduction, skin exposure and respiratory protection. Eur Respir Rev 21:112–24
  • Henjakovic M, Martin C, Hoymann HG, et al. (2008). Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies. Toxicol Sci 106:444–53
  • Karlberg AT, Shao LP, Nilsson U, et al. (1994). Hydroperoxides in oxidized d-limonene identified as potent contact allergens. Arch Dermatol Res 286:97–103
  • Kimber I, Agius R, Basketter DA, et al. (2007). Chemical respiratory allergy: opportunities for hazard identification and characterisation. The report and recommendations of ECVAM workshop 60. Altern Lab Anim 35:243–65
  • Kimber I, Basketter DA, Gerberick GF, et al. (2011). Chemical allergy: translating biology into hazard characterization. Toxicol Sci 120:S238–68
  • Masuck I, Hutzler C, Jann O, Luch A. (2011). Inhalation exposure of children to fragrances present in scented toys. Indoor Air 21:501–11
  • Park MVDZ, Delmaar JE, Van Engelen JGM. (2006). Comparison of consumer exposure modelling tools. Inventory of possible improvements of ConsExpo RIVM report 320104006
  • Pronk A, Preller L, Raulf-Heimsoth M, et al. (2007). Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates. Am J Respir Crit Care Med 176:1090–7
  • Pronk A, Tielemans E, Skarping G, et al. (2006). Inhalation exposure to isocyanates of car body repair shop workers and industrial spray painters. Ann Occup Hyg 50:1–14
  • Quirce S, Fernández-Nieto M, Pozo VD, et al. (2008). Occupational asthma and rhinitis caused by eugenol in a hairdresser. Allergy 63:137–8
  • Redlich CA. (2010). Skin exposure and asthma: is there a connection? Proc Am Thorac Soc 7:134–7
  • SCCS (Scientific Committee on Consumer Safety). Opinion on fragrance allergens in cosmetic products, 26–27 June 2012. Available from: http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_102.pdf. [Last accessed: 19 Feb 2014]
  • Schnuch A, Uter W, Geier J, Gefeller O. (2002). Epidemiology of contact allergy: an estimation of morbidity employing the clinical epidemiology and drug-utilization research (CE-DUR) approach. Contact Dermatitis 47:32–9
  • Schnuch A, Uter W, Geier J, et al. (2007). Sensitization to 26 fragrances to be labelled according to current European regulation. Results of the IVDK and review of the literature. Contact Dermatitis 57:1–10
  • Skold M, Borje A, Harambasic E, Karlberg AT. (2004). Contact allergens formed on air exposure of linalool. Identification and quantification of primary and secondary oxidation products and the effect on skin sensitization. Chem Res Toxicol 17:1697–705
  • Slob W. (2002). Dose-response modeling of continuous endpoints. Toxicol Sci 66:298–312
  • Uter W, Geier J, Frosch P, Schnuch A. (2010). Contact allergy to fragrances: current patch test results (2005–2008) from the Information Network of Departments of Dermatology. Contact Dermatitis 63:254–61
  • Van Och FM, Slob W, De Jong WH, et al. (2000). A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins. Toxicology 146:49–59
  • Van Triel JJ, Arts JHE, Muijser H, Kuper CF. (2010). Allergic inflammation in the upper respiratory tract of the rat upon repeated inhalation exposure to the contact allergen dinitrochlorobenzene (DNCB). Toxicology 269:73–80
  • Van Triel JJ, Van Bree BWJ, Roberts DW, et al. (2011). The respiratory allergen glutaraldehyde in the local lymph node assay: sensitization by skin exposure, but not by inhalation. Toxicology 279:115–22
  • Vandebriel RJ, De Jong WH, Spiekstra SW, et al. (2000). Assessment of preferential T-Helper 1 or T-Helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for Interferon-gamma and Interleukin-4. Toxicol Appl Pharmacol 162:77–85
  • Vandenplas O. (2011). Occupational asthma: etiologies and risk factors. Allergy Asthma Immunol Res 3:157–67
  • Vanoirbeek JAJ, Mandervelt C, Cunningham AR, et al. (2003). Validity of methods to predict the respiratory sensitizing potential of chemicals: a study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma. Toxicol Sci 76:338–46
  • Vanoirbeek JAJ, Tarkowski M, Vanhooren HM, et al. (2006). Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer. J Allergy Clin Immunol 117:1090–7

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