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Research Article

Clinical and pathological manifestations of cardiovascular disease in rat models: the influence of acute ozone exposure

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Pages 26-38 | Received 09 Apr 2014, Accepted 07 Aug 2014, Published online: 15 Dec 2015

References

  • Ariyoshi K, Maruyama T, Odashiro K, et al. (2010). Impaired erythrocyte filterability of spontaneously hypertensive rats: investigation by nickel filtration technique. Circ J 74:129–36
  • Bauer AK, Travis EL, Malhotra SS, et al. (2010). Identification of novel susceptibility genes in ozone-induced inflammation in mice. Eur Respir J 36:428–37
  • Bhalla DK, Gupta SK. (2000). Lung injury, inflammation, and inflammatory stimuli in rats exposed to ozone. J Toxicol Environ Health A 59:211–28
  • Bhaskaran K, Hajat S, Haines A, et al. (2009). Effects of air pollution on the incidence of myocardial infarction. Heart 95:1746–59
  • Brunner F, Wolkart G, Pfeiffer S, et al. (2000). Vascular dysfunction and myocardial contractility in the JCR:LA-corpulent rat. Cardiovasc Res 47:150–8
  • Budinger GR, Mutlu GM. (2011). Update in environmental and occupational medicine 2010. Am J Respir Crit Care Med 183:1614–19
  • Carneado J, Alvarez de Sotomayor M, Perez-Guerrero C, et al. (2002). Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect. J Hypertens 20:429–37
  • Cassee FR, Boere AJ, Bos J, et al. (2002). Effects of diesel exhaust enriched concentrated PM2.5 in ozone preexposed or monocrotaline-treated rats. Inhal Toxicol 14:721–43
  • Cassee FR, Boere AJ, Fokkens PH, et al. (2005). Inhalation of concentrated particulate matter produces pulmonary inflammation and systemic biological effects in compromised rats. J Toxicol Environ Health A 68:773–96
  • Chang LY, Huang Y, Stockstill BL, et al. (1992). Epithelial injury and interstitial fibrosis in the proximal alveolar regions of rats chronically exposed to a simulated pattern of urban ambient ozone. Toxicol Appl Pharmacol 115:241–52
  • Chen LL, Tager IB, Peden DB, et al. (2004). Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects. Chest 125:2328–35
  • Danesh J, Lewington S, Thompson SG, et al. (2005). Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA 294:1799–809
  • de Keijzer MH, Provoost AP, Molenaar JC. (1989). Proteinuria is an early marker in the development of progressive renal failure in hypertensive fawn-hooded rats. J Hypertens 7:525–8
  • Dormans JA, van Bree L, Boere AJ, et al. (1999). Interspecies differences in time course of pulmonary toxicity following repeated exposure to ozone. Inhal Toxicol 11:309–29
  • Dye JA, Ledbetter AD, Schladweiler MC, et al. (2015). Whole body plethysmography reveals differential ventilatory responses to ozone in rat models of cardiovascular disease. Inhal Toxicol 27 (S1):14–15
  • Eisenberg S, Rachmilewitz D. (1973). Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of the whole lipoprotein. Biochim Biophys Acta 326:378–90
  • Ernst E, Resch KL. (1993). Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature. Ann Intern Med 118:956–63
  • Ernst E, Weihmayr T, Schmid M, et al. (1986). Cardiovascular risk factors and hemorheology. Physical fitness, stress and obesity. Atherosclerosis 59:263–9
  • Ghio AJ, Hall A, Bassett MA, et al. (2003). Exposure to concentrated ambient air particles alters hematologic indices in humans. Inhal Toxicol 15:1465–78
  • Gomibuchi H, Okazaki M, Iwai S, et al. (2007). Development of hyperfibrinogenemia in spontaneously hypertensive and hyperlipidemic rats: a potentially useful animal model as a complication of hypertension and hyperlipidemia. Exp Anim 56:1–10
  • Hazari MS, Haykal-Coates N, Winsett DW, et al. (2009). A single exposure to particulate or gaseous air pollution increases the risk of aconitine-induced cardiac arrhythmia in hypertensive rats. Toxicol Sci 112:532–42
  • Herring N, Lee CW, Sunderland N, et al. (2011). Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat. J Mol Cell Cardiol 50:99–106
  • Hollingsworth JW, Kleeberger SR, Foster WM. (2007). Ozone and pulmonary innate immunity. Proc Am Thorac Soc 4:240–6
  • Iritani N, Fukuda E, Nara Y, Yamori Y. (1977). Lipid metabolism in spontaneously hypertensive rats (SHR). Atherosclerosis 28:217–22
  • Jerrett M, Burnett RT, Pope CA III, et al. (2009). Long-term ozone exposure and mortality. N Engl J Med 360:1085–95
  • Kannel WB. (1997). Influence of fibrinogen on cardiovascular disease. Drugs 54:32–40
  • Kelly FJ, Fussell JC. (2011). Air pollution and airway disease. Clin Exp Allergy 41:1059–71
  • Kittel B, Ruehl-Fehlert C, Morawietz G, et al. (2004). Revised guides for organ sampling and trimming in rats and mice--Part 2. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol 55:413–31
  • Kodavanti UP, Costa DL, Bromberg PA. (1998). Rodent models of cardiopulmonary disease: their potential applicability in studies of air pollutant susceptibility. Environ Health Perspect 106:111–30
  • Kodavanti UP, Moyer CF, Ledbetter AD, et al. (2003). Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat. Toxicol Sci 71:237–45
  • Kodavanti UP, Russell JC, Costa DL. (2015a). Rat models of cardiometabolic diseases: baseline clinical chemistries, and rationale for their use in examining air pollution health effects. Inhal Toxicol 27 (S1):2–13
  • Kodavanti UP, Schladweiler MC, Ledbetter AD, et al. (2000). The spontaneously hypertensive rat as a model of human cardiovascular disease: evidence of exacerbated cardiopulmonary injury and oxidative stress from inhaled emission particulate matter. Toxicol Appl Pharmacol 164:250–63
  • Kodavanti UP, Schladweiler MC, Ledbetter AD, et al. (2002). Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats. J Toxicol Environ Health A 65:1545–69
  • Kodavanti UP, Thomas R, Ledbetter AD, et al. (2011). Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles. Environ Health Perspect 119:312–18
  • Kodavanti UP, Ledbetter AD, Thomas RF, et al. (2015b). Variability in ozone-induced pulmonary injury and inflammation in healthy and cardiovascular compromised rat models. Inhal Toxicol 27 (S1):39–53
  • Koenig W, Ernst E. (1992). The possible role of hemorheology in atherothrombogenesis. Atherosclerosis 94:93–107
  • McNamee CJ, Kappagoda CT, Kunjara R, Russell JC. (1994). Defective endothelium-dependent relaxation in the JCR:LA-corpulent rat. Circ Res 74:1126–32
  • Minhas KM, Saraiva RM, Schuleri KH, et al. (2006). Xanthine oxidoreductase inhibition causes reverse remodeling in rats with dilated cardiomyopathy. Circ Res 98:271–9
  • Monti J, Fischer J, Paskas S, et al. (2008). Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nat Genet 40:529–37
  • Morawietz G, Ruehl-Fehlert C, Kittel B, et al. (2004). Revised guides for organ sampling and trimming in rats and mice--Part 3. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol 55:433–49
  • Mustafic H, Jabre P, Caussin C, et al. (2012). Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA 307:713–21
  • Nyska A, Murphy E, Foley JF, et al. (2005). Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine. Toxicol Sci 83:388–96
  • Ochodnicky P, Henning RH, Buikema HJ, et al. (2010). Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat. Am J Physiol Renal Physiol 298:F625–33
  • Oschry Y, Eisenberg S. (1982). Rat plasma lipoproteins: re-evaluation of a lipoprotein system in an animal devoid of cholesteryl ester transfer activity. J Lipid Res 23:1099–106
  • Provoost AP. (1994). Spontaneous glomerulosclerosis: insights from the fawn-hooded rat. Kidney Int Suppl 45:S2–5
  • Reimer RA, Russell JC. (2008). Glucose tolerance, lipids, and GLP-1 secretion in JCR:LA-cp rats fed a high protein fiber diet. Obesity (Silver Spring) 16:40–6
  • Ruehl-Fehlert C, Kittel B, Morawietz G, et al. (2003). Revised guides for organ sampling and trimming in rats and mice--part 1. Exp Toxicol Pathol 55:91–106
  • Russell JC, Amy RM. (1986). Plasma lipids and other factors in the LA/N corpulent rat in the presence of chronic exercise and food restriction. Can J Physiol Pharmacol 64:750–6
  • Russell JC, Kelly SE, Vine DF, Proctor SD. (2009). Irbesartan-mediated reduction of renal and cardiac damage in insulin resistant JCR:LA-cp rats. Br J Pharmacol 158:1588–96
  • Russell JC, Proctor SD. (2006). Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis. Cardiovasc Pathol 15:318–30
  • Shackelford C, Long G, Wolf J, et al. (2002). Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies. Toxicol Pathol 30:93–6
  • Shannahan JH, Nyska A, Cesta M, et al. (2012a). Subchronic pulmonary pathology, iron overload, and transcriptional activity after Libby amphibole exposure in rat models of cardiovascular disease. Environ Health Perspect 120:85–91
  • Shannahan JH, Schladweiler MC, Richards JH, et al. (2010). Pulmonary oxidative stress, inflammation, and dysregulated iron homeostasis in rat models of cardiovascular disease. J Toxicol Environ Health A 73:641–56
  • Shannahan JH, Schladweiler MC, Thomas RF, et al. (2012b). Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. J Toxicol Environ Health A 75:213–31
  • Simons JL, Provoost AP, Anderson S, et al. (1993). Pathogenesis of glomerular injury in the fawn-hooded rat: early glomerular capillary hypertension predicts glomerular sclerosis. J Am Soc Nephrol 3:1775–82
  • Srebot V, Gianicolo EA, Rainaldi G, et al. (2009). Ozone and cardiovascular injury. Cardiovasc Ultrasound 7:1--8
  • Stafoggia M, Forastiere F, Faustini A, et al. (2010). Susceptibility factors to ozone-related mortality: a population-based case-crossover analysis. Am J Respir Crit Care Med 182:376–84
  • Steinvil A, Kordova-Biezuner L, Shapira I, et al. (2008). Short-term exposure to air pollution and inflammation-sensitive biomarkers. Environ Res 106:51–61
  • Tofovic SP, Jackson EK. (2003). Rat models of the metabolic syndrome. Methods Mol Med 86:29–46
  • van Bree L, Dormans JA, Boere AJ, Rombout PJ. (2001). Time study on development and repair of lung injury following ozone exposure in rats. Inhal Toxicol 13:703–18
  • van Dokkum RP, Sun CW, Provoost AP, et al. (1999). Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. Am J Physiol 276:R855–63
  • Vine DF, Takechi R, Russell JC, Proctor SD. (2007). Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome. Atherosclerosis 190:282–90
  • Wallenborn JG, Schladweiler MC, Nyska A, et al. (2007). Cardiopulmonary responses of Wistar Kyoto, spontaneously hypertensive, and stroke-prone spontaneously hypertensive rats to particulate matter (PM) exposure. J Toxicol Environ Health A 70:1912–22
  • Watkinson WP, Campen MJ, Nolan JP, Costa DL. (2001). Cardiovascular and systemic responses to inhaled pollutants in rodents: effects of ozone and particulate matter. Environ Health Perspect 109:539–46
  • Windler E, Chao YS, Havel RJ. (1980). Determinants of hepatic uptake of triglyceride-rich lipoproteins and their remnants in the rat. J Biol Chem 255:5475–80
  • Young GS, Fox MA, Trush M, et al. (2012). Differential exposure to hazardous air pollution in the United States: a multilevel analysis of urbanization and neighborhood socioeconomic deprivation. Int J Environ Res Public Health 9:2204–25

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