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Inhalation Toxicology
International Forum for Respiratory Research
Volume 27, 2015 - Issue 11
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Research Article

Health effects of soy-biodiesel emissions: bioassay-directed fractionation for mutagenicity

Esra MutluNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA, ;Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, NC, USA,
,
Sarah H. WarrenNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA,
,
Peggy P. MatthewsNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA,
,
Judith E. SchmidNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA,
,
Ingeborg M. KooterDepartment of Applied Environmental Chemistry, TNO, Utrecht, The Netherlands, and
,
William P. LinakNational Risk Management Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA
,
M. Ian GilmourNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA,
&
David M. DeMariniNational Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA, Correspondence[email protected]
 show all
Pages 597-612 | Received 04 Jun 2015, Accepted 02 Sep 2015, Published online: 30 Oct 2015

References

  • Bünger J, Krahl J, Schröder O, et al. (2012). Potential hazards associated with combustion of bio-derived versus petroleum-derived diesel fuel. Crit Rev Toxicol 42:732–50
  • DeMarini DM, Brooks LR, Warren SH, et al.(2004). Bioassay-directed fractionation and Salmonella mutagenicity of automobile and forklift diesel exhaust particles. Environ Health Perspect 112:814–19
  • International Agency for Research on Cancer, IARC. Monographs on the Evaluation of Carcinogenic Risks to Humans. (2014). Diesel and gasoline engine exhausts and some nitroarenes. Monogr Eval Carcinog Risks Hum 105:1–704
  • Kooter IM, van Vugt MATM, Jedynska AD, et al. (2011). Toxicological characterization of diesel engine emissions using biodiesel and a closed soot filter. Atmos Environ 45:1574–80
  • Lewtas J, King LC, Williams K, et al. (1990). Bioassay-directed fractionation of 1-nitropyrene metabolites: generation of mutagrams by coupling reverse-phase HPLC with microsuspension mutagenicity assays. Mutagenesis 5:481–9
  • Madden MC. (2015). Overview of biodiesel studies. Inhal Toxicol 27:511–14
  • Mutlu E, Nash DG, King C, et al. (2015a). Generation, characterization, and comparison of diesel engine emissions from petroleum and soybean biodiesel fuels and the application for inhalation exposure studies. Inhal Toxicol 27:515–32
  • Mutlu E, Warren SH, Matthews PP, et al. (2013). Bioassay-directed fractionation and sub-fractionation for mutagenicity and chemical analysis of diesel exhaust particles. Environ Mol Mutagen 54:719–36
  • Mutlu E, Warren SH, Matthews PP, et al. (2015b). Health effects of soy-biodiesel emissions: mutagenicity-emission factors. Inhal Toxicol 27:585–96
  • Swanson KJ, Madden MC, Ghio AJ. (2007). Biodiesel exhaust: the need for health effects research. Environ Health Perspect 115:496–99
  • Turrio-Baldassarri L, Battistelli CL, Conti L, et al. (2004). Emission comparison of urban bus engine fueled with diesel oil and “biodiesel” blend. Sci Total Environ 327:147–62
  • Yan J, Wang L, Fu PP, et al. (2004). Photomutagenicity of 16 polycyclic aromatic hydrocarbons from the US EPA priority pollutant list. Mutat Res 557:99–108

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