Advanced search
Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 6, 1994 - Issue 4
Submit an article Journal homepage
5
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Increased Incidence of DNA Double-Strand Breaks in Lung and Liver of Rats After Exposure to Crocidolite Asbestos Fibers

B. Marczynski Research Institute of Occupational Medicine, University of Bochum, Bochum, Germany
,
T. Kerenyi Research Institute of Occupational Medicine, University of Bochum, Bochum, Germany; Department of Pathology, Hospital of the Medical University, Robert-Karoly krt. 44, Budapest, Hungary
,
A. B. Czuppon Research Institute of Occupational Medicine, University of Bochum, Bochum, Germany
,
W. Marek Research Institute of Occupational Medicine, University of Bochum, Bochum, Germany
&
X. Baur Research Institute of Occupational Medicine, University of Bochum, Bochum, Germany
Pages 395-406 | Received 29 Nov 1993, Accepted 01 Feb 1994, Published online: 27 Sep 2008

References

  • Adachi S., Kawamura K., Yoshida S., Takemoto K. Oxidative damage on DNA induced by asbestos and man-made fibers in vitro. Int. Arch. Occup. Environ. Health 1992; 63: 553–557
  • Appel J. D., Fasy T. M., Kohtz D. S., Kohtz J. D., Johnson E. M. Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. Proc. Natl. Acad. Sci. USA 1988; 85: 7670–7674
  • Babu K. A., Nigam S. K., Lakkad B. C, et al. Effect of chrysotile asbestos (AP-1) on sister chro-matid exchanges in Chinese hamster ovary cells. Environ. Res. 1981; 24: 325–329
  • Brown C. M., Cowie H., Davis J. M.C., Donaldson K. In vitro assays for detecting carcinogenic mineral fibers: A comparison of two assays and the role of fiber size. Carcinogenesis 1986; 7: 1971–1974
  • Craighead J. E., Akley N. J., Gould L. B., Libbus B. L. Characteristics of tumors and tumor cells from experimental asbestos-induced mesothelioma in rats. Am. J. Pathol. 1987; 129: 448–462
  • Gardiner K., Laas W., Patterson D. Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis. Somat. Cell Mol. Genet. 1986; 12: 185–195
  • Ghio A. J., Zhang J., Piantadosi C. A. Generation of hydroxyl radical by crocidolite asbestos is proportional to surface [Fe*]. Arch. Biochem. Biophys. 1992; 298: 646–650
  • Hesterberg T. W., Barrett J. C. Dependence of asbestos- and mineral dust-induced transformation of mammalian cells in culture on fiber dimension. Cancer Res. 1984; 44: 2170–2180
  • Jaurand M. C, Kheuang L., Magne L., Bignon J. Chromosomal changes induced by chrysotile or benzo-3,4-pyrene in rat pleural mesothelial cells. Mutat. Res. 1986; 169: 141–148
  • Kamp D. W., Graceffa P., Pryor W. A., Weitzman S. A. The role of free radicals in asbestos-induced diseases. Free Radical Biol. Med. 1992; 12: 293–315
  • Kasai H., Nashimura S. DNA damage induced by asbestos in the presence of hydrogen peroxide. Gann 1984; 75: 841–844
  • Kerenyi T., Voss B., Möller K.-M. Asbestos-induced well-differentiated papillary mesothel-proliferation of the pleura in rats. Eur. Respir. J. 1992; 5: 381s, Suppl. 15
  • Libbus B. L., Illenye S. A., Craighead J. E. Induction of DNA strand breaks in cultured rat embryo cells by crocidolite asbestos as assessed by nick translation. Cancer Res. 1989; 49: 5713–5718
  • Lund L. G., Aust A. E. Iron mobilization from asbestos by chelators and ascorbic acid. Arch. Biochem. Biophys. 1990; 278: 60–64
  • Lund L. G., Aust A. E. Mobilization of iron from crocidolite asbestos by certain chelators in enhanced crocidolite-dependent oxygen consumption. Arch. Biochem. Biophys. 1991; 287: 91–96
  • Lund L. G., Aust A. E. Iron mobilization from crocidolite asbestos greatly enhances crocidolite-dependent formation of DNA single-strand breaks in ØX174 RFI DNA. Carcinogenesis 1992; 13: 637–642
  • Peto J., Seidman H., Selikoff I. J. Mesothelioma mortality in asbestos workers: Implications for models of carcinogenesis and risk assessment. Br. J. Cancer 1982; 45: 124–135
  • Price-Jones M. J., Gubbings G., Chamberlain M. The genetic effects of crocidolite asbestos: Comparison of chromosome abnormalities and sister-chromatid exchanges. Mutat. Res. 1980; 79: 331–336
  • Rickwood D., Birnie G. D. Preparation, characterization and fractionation of chromatin. Subnuclear components, preparation and fractionation, G. D. Birnie. Butterworth, London 1976; 129–180
  • Rom W. N., Livingston G. K., Casey K. R., et al. Sister chromatid exchange frequency in asbestos workers. JNCI 1983; 70: 45–48
  • Sincock A. M., Seabright M. Induction of chromosome changes in Chinese hamster cells by exposure to asbestos fibers. Nature 1975; 275: 56–58
  • Valerio F., de Ferrari M., Ottaggio L., Repetto E., Santi L. Chromosomal aberrations induced by chrysotile and crocidolite in human lymphocytes in vitro. Mutat. Res. 1983; 122: 397–402
  • Zalma R., Guingard J., Pezerat H., Jaurand M.-C. Formation of oxy radicals by oxygen reduction arising from the surface activity of asbestos. Can. J. Chem. 1988; 65: 2338–2341

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.