Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 7, 1995 - Issue 1
33
Views
36
CrossRef citations to date
0
Altmetric
Research Article

Toxicological Evidence for Health Effects from Inhaled Particulate Pollution: Does it Support the Human Experience?

Pages 99-109 | Published online: 27 Sep 2008

References

  • Amdur M. O. Sulfuric acid: The animals tried to tell us. Appl. Ind. Hyg. 1989; 4: 189–197
  • Amdur M. O., Chen L. C. Furnace-generated acid aerosols: Speciation and pulmonary effects. Environ. Health Perspect 1989; 79: 147–150
  • Balmes J R. The role of ozone exposure in the epidemiology of asthma. Environ. Health Perspect 1993; 101(suppl. 4)219–224
  • Chen L. C., Wu C. Y., Qu Q. S., Schlesinger R. B. Presented at Colloquium on Particulate Air Pollution and Human Mortality and Morbidity. Irvine, CA, 24–25 January, 1994, Number concentration and mass concentration as determinants of biological response to inhaled irritant particles
  • Chen L. C., Lam H. F., Kim E. I., Cuty I., Amdur M. O. Pulmonary effects of ultrafine coal fly ash inhaled by guinea pigs. J. Toxicol. Environ. Health 1990; 29: 169–184
  • Dockery D. W., Pope C. A., III, Xu X., Spengler J. D., Ware J. H., Fay M. E., Ferris B. C., Jr., Speizer F. E. An association between air pollution and mortality in six U.S. cities. N. Engl. J. Med. 1993; 329: 1753–1759
  • Ehrlich R. Interaction between environmental pollutants and respiratory infections, E. P. C.D. E. Hli Gardner, J. A. Graham. U.S. EPA, Park, NC 1979; 145–163, Proc. Symp. Experimental Models for Pulmonary Research. EPA-600/9–79–022. Research Triangle
  • El-Fawal H. A. N., Schlesinger R. B. Nonspecific airway hyperresponsiveness induced by inhalation exposure to sulfuric acid aerosol: An in vitro assessment. Toxicol. Appl. Pharmacol. 1994; 125: 70–76
  • Ferin J., Oberdörster C., Penney D. P. Pulmonary retention of ultrafine and fine particles in rats. Am. J. Respir. Cell Mol. Biol. 1992; 6: 535–542
  • Cearhart J. M., Schlesinger R. B. Sulfuric acid-induced changes in the physiology and structure of the tracheobronchial airways. Environ. Health Perspect 1989; 79: 127–137
  • Goyer R. A. Toxic effects of metals. Toxicology, C. D. Klaassen, M. O. Amdur, J. Doull. Macmillan, New York 1986; 582–635
  • Hill A. B. The environment and disease: Association or causation. Proc. R. Soc. Med. 1965; 58: 295–300
  • Kimmel T. A., Chen L. C., Bosland M. C., Nadziejko C. Effect of acid droplet size on morphologic changes in the rat lung following acute exposure to O3 and/or H2 SO4 aerosol. Toxicologist 1994; 14, in Press
  • Kleinman M. T., Bhalla D. K., Mautz W. I., Phalen R. F. (1994) Presented at Colloquium on Particulate Air Pollution and Human Mortality and Morbidity. Irvine, CA, 24–25 January, 1994, Cellular and immunologic injury with PM-10 inhalation
  • Klingenberg H., Winneke H. Studies on health effects of automotive exhaust emissions. How dangerous are diesel emissions. Sci. Total Environ. 1990; 93: 95–105
  • Lippmann M., Gearhar J. M., Schlesinger R. B. Basis for a particle size-selective TLV for sulfuric acid aerosols. Appl. Ind. Hyg. 1987; 2: 188–199
  • Mauderly J. L. Diesel exhaust. Environmental toxicants: Human exposures and their health effects, M. Lippmann. Van Nostrand Reinhold, New York 1992; 119–162
  • McGovern T. J., Schlesinger R. B., El-Fawal H. A. N. Effect of repeated in vivo ozone and/or sulfuric acid exposures on in vitro airway hyperresponsiveness and B-adrenergic modulation of macrophage function. Toxicologist 1993; 13: 49
  • Nemery B. Metal toxicity and the respiratory tract. Eur. Respir. J. 1990; 3: 202–219
  • Oberdorster G. Lung clearance of inhaled insoluble and soluble particles. J. Aerosol Sci. 1988; 1: 289–330
  • Oberdörster C., Gelein R., Corson N., Mercer P. Presented at Colloquium on Particulate Air Pollution and Human Mortality and Morbidity. Irvine, CA, 24–25 January, 1994, Association of particulate air pollution and acute mortality: Involvement of ultrafine particles?
  • Ostro B. The association of air pollution and mortality: Examining the case for inference. Arch. Environ. Health. 1993; 48: 336–342
  • Pope C. A., III, Dockery D. W., Spengler J. D., Raizenne M. E. Respiratory health and PM-10 pollution. A time series analysis. Am. Rev. Respir. Dis. 1991; 144: 668–674
  • Sackner M. A., Dougherty R. D., Chapman C. A. Effect of inorganic nitrate and sulfate salts on cardiopulmonary function. Am. Rev. Respir. Dis. 1976; 113(suppl)89
  • Saldiva P. H., King M., Delmonte V. L., Macchione M., Parada M. A., Daliberto M. L., Sakae R. S., Criado P. M., Silveira P. L., Zin W. A. Respiratory alterations due to urban air pollution: An experimental study in rats. Environ. Res. 1992; 57: 19–33
  • Scheepers P. T. J., Bos R. P. Combustion of diesel fuel from a toxicological perspective. II. Toxicity. Int. Arch. Occup. Environ. Health 1992; 64: 163–177
  • Schlesinger R. B. Factors affecting the response of lung clearance systems to acid aerosols: Role of exposure concentration, exposure duration and relative acidity. Environ. Health Perspect 1989; 79: 121–126
  • Schlesinger R. B. The interaction of inhaled toxicants with respiratory tract clearance mechanisms. Crit. Rev. Toxicol. 1990; 20: 257–286
  • Schlesinger R. B. Nitrogen oxides. Environmental toxicants: Human exposures and their health effects, M. Lippmann. Van Nostrand Reinhold, New York 1992; 412–453
  • Schlesinger R. B., Zelikoff J. T., Chen L. C., Kinney P. L. Assessment of toxicologic interactions resulting from acute inhalation exposure to sulfuric acid and ozone mixtures. Toxicol. Appl. Pharmacol. 1992; 115: 183–190
  • Schwartz J. Particulate air pollution and chronic respiratory disease. Environ. Res. 1993; 62: 7–13
  • Schwartz J. What are people dying of on high air pollution days?. Environ. Res. 1994; 64: 26–35
  • Sherwin R. P., Richters V. Influence of community air pollution on the lungs of mice. Part I: Hyperplasia and hypertrophy of type 2 cells, and increase in alveolar wall area. Inhal. Toxicol. 1991; 3: 37–47
  • Spengler J. D., Keeler G. J., Koutrakis P., Ryan P. B., Raizenne M., Franklin C. A. Exposures to acidic aerosols. Environ. Health Perspect 1989; 79: 43–51
  • U.S. Environmental Protection Agency. U. S. EPA, Washington 1989, An Acid Aerosols Issue Paper. EPA/600/8–88/005F
  • Zelikoff J. T., Sclilesinger R. B. Modulation of pulmonary immune defense mechanisms by sulfuric acid: Effects on macrophage-derived tumor necrosis factor and superoxide. Toxicology 1992; 76: 271–281
  • Lelikoff J. T., Sisco M. P., Yang A., Cohen M. D., Schlesinger R. B. Immunotoxicity of sulfuric acid aerosol: Effects on pulmonary macrophage effector and functional activities critical for maintaining host resistance against infectious diseases. Toxicology 1994, in Press

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.